CST3 (cystatin C) - Rat Genome Database

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Gene: CST3 (cystatin C) Sus scrofa
Analyze
Symbol: CST3
Name: cystatin C
RGD ID: 14157592
Description: ENCODES a protein that exhibits endopeptidase inhibitor activity (ortholog); peptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN apoptotic process (ortholog); brain development (ortholog); cell activation (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); acute myeloid leukemia (ortholog); age related macular degeneration 11 (ortholog); FOUND IN axon (ortholog); basement membrane (ortholog); cell projection (ortholog); INTERACTS WITH progesterone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cystatin-C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,470,855 - 30,474,590 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,471,056 - 30,474,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21734,560,206 - 34,563,637 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
progesterone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:20107207  


Genomics

Comparative Map Data
CST3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,470,855 - 30,474,590 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,471,056 - 30,474,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21734,560,206 - 34,563,637 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CST3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2023,626,706 - 23,638,473 (-)EnsemblGRCh38hg38GRCh38
GRCh382023,626,706 - 23,637,955 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372023,607,343 - 23,618,592 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362023,562,294 - 23,566,574 (-)NCBINCBI36hg18NCBI36
Build 342023,562,293 - 23,566,574NCBI
Celera2023,687,561 - 23,691,841 (-)NCBI
Cytogenetic Map20p11.21NCBI
HuRef2023,574,763 - 23,578,930 (-)NCBIHuRef
CHM1_12023,614,330 - 23,618,610 (-)NCBICHM1_1
Cst3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392148,713,642 - 148,717,432 (-)NCBIGRCm39mm39
GRCm39 Ensembl2148,713,642 - 148,717,612 (-)Ensembl
GRCm382148,871,722 - 148,875,512 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2148,871,722 - 148,875,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv372148,697,468 - 148,701,204 (-)NCBIGRCm37mm9NCBIm37
MGSCv362148,563,173 - 148,566,909 (-)NCBImm8
Celera2150,137,951 - 150,141,688 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.6NCBI
Cst3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23136,336,923 - 136,340,796 (-)NCBI
Rnor_6.0 Ensembl3143,219,686 - 143,223,615 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03143,219,671 - 143,223,544 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03149,628,692 - 149,632,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43137,650,903 - 137,654,776 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13137,556,481 - 137,560,243 (-)NCBI
Celera3135,178,032 - 135,181,905 (-)NCBICelera
Cytogenetic Map3q41NCBI
Cst3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541530,507,972 - 30,512,109 (-)NCBIChiLan1.0ChiLan1.0
CST3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12023,935,942 - 23,940,420 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2023,935,942 - 23,940,425 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02023,583,043 - 23,587,399 (-)NCBIMhudiblu_PPA_v0panPan3
LOC607874
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12349,562 - 53,618 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2381,423 - 85,399 (-)NCBI
ROS_Cfam_1.023292,507 - 296,492 (-)NCBI
UMICH_Zoey_3.123151,270 - 155,246 (-)NCBI
UNSW_CanFamBas_1.023233,470 - 237,470 (-)NCBI
UU_Cfam_GSD_1.023222,517 - 226,484 (-)NCBI
CST3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1252,834,497 - 52,838,785 (-)NCBI
ChlSab1.1 Ensembl252,832,181 - 52,838,865 (-)Ensembl
Vero_WHO_p1.0NW_02366605092,907,879 - 92,912,191 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000038762   ⟹   ENSSSCP00000053827
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1730,470,855 - 30,474,590 (-)Ensembl
RefSeq Acc Id: NM_001044602   ⟹   NP_001038067
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11730,471,056 - 30,474,486 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001038067 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABG48755 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001038067   ⟸   NM_001044602
- Peptide Label: precursor
- UniProtKB: Q0Z8R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000053827   ⟸   ENSSSCT00000038762
Protein Domains
Cystatin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037360 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070021771 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000053827 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070036411 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000038762 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070043272 UniProtKB/TrEMBL
InterPro Cystatin_dom UniProtKB/TrEMBL
  Prot_inh_cystat_CS UniProtKB/TrEMBL
KEGG Report ssc:733672 UniProtKB/TrEMBL
NCBI Gene CST3 ENTREZGENE
Pfam Cystatin UniProtKB/TrEMBL
PROSITE CYSTATIN UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
UniProt A0A4X1V498_PIG UniProtKB/TrEMBL
  Q0Z8R0 ENTREZGENE, UniProtKB/TrEMBL