Gene: Anks6 (ankyrin repeat and sterile alpha motif domain containing 6) Rattus norvegicus
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Symbol: Anks6
Name: ankyrin repeat and sterile alpha motif domain containing 6
Description: ENCODES a protein that exhibits protein homodimerization activity; INVOLVED IN determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH polycystic kidney disease; autosomal dominant polycystic kidney disease (ortholog); Cardiovascular Abnormalities (ortholog); FOUND IN cytoplasm; INTERACTS WITH acrylamide; bisphenol A; copper atom
AGR Description: Exhibits protein homodimerization activity; predicted to be involved in determination of left/right symmetry and heart development; localizes to the cytoplasm; used to study polycystic kidney disease; orthologous to human ANKS6 (ankyrin repeat and sterile alpha motif domain containing 6).
Merged Description: Exhibits protein homodimerization activity; predicted to be involved in determination of left/right symmetry and heart development; localizes to the cytoplasm; used to study polycystic kidney disease; orthologous to human ANKS6 (ankyrin repeat and sterile alpha motif domain containing 6); INTERACTS WITH acrylamide; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ankyrin repeat and SAM domain-containing protein 6; LOC362515; MGC109646; Pkdr1; Pkdr1_mapped; polycystic kidney disease protein 1; polycystic kidney disease rat 1; polycystic kidney disease rat 1 (mapped); SAM domain-containing protein 6; samcystin; Samd6; sterile alpha motif domain containing 6; sterile alpha motif domain-containing protein 6
Orthologs:
Allele / Splice: Anks6PKD  
Genetic Models: SPRD-Anks6PKD/Rrrc SPRD-Anks6PKD/Fsn
Is Marker For: Strains:   SPRD-Anks6PKD/Fsn   SPRD-Anks6PKD/Rrrc  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0562,642,974 - 62,684,387 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0567,163,440 - 67,204,853 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,633,540 - 63,674,953 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1563,632,332 - 63,674,981 (-)NCBI
Celera559,865,938 - 59,907,349 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Anks6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3334
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.