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Strain: F344-Il2rgem2Kyo

Symbol: F344-Il2rgem2Kyo
Strain: F344-Il2rgem2
Substrain: Kyo
RGD ID: 9685748
Citation ID: RRID:RGD_9685748
Ontology ID: RS:0003850
Alleles: Il2rgem2Kyo
Also Known As: X-SCID; NBRP Rat No: 0586; F344-Il2rgem2Kyo; F344-Il2rg^[em2Kyo]
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: The severe combined immunodeficiency strain carries a zinc finger induced 1097-bp deletion mutation of Il2rg gene created in the F344/Stm embryos.
Coat Color: albino
Inbred Generations: N1F9
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-03-27)
Research Usage Immunology
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X66,395,330 - 66,399,026RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X71,165,378 - 71,169,078RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X72,017,856 - 72,021,516RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4X89,342,055 - 89,345,715RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations     Click to see Annotation Detail View


References - curated
# Reference Title Reference Citation
1. Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases. Mashimo T, etal., PLoS One. 2010 Jan 25;5(1):e8870.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information