(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of GAD1 mRNA CTD PMID:16797850 (-)-epigallocatechin 3-gallate increases expression EXP 6480464 epigallocatechin gallate results in increased expression of GAD1 protein CTD PMID:27659729 (R)-lipoic acid multiple interactions EXP 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of GAD1 mRNA CTD PMID:31068541 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of GAD1 mRNA, Nicotine results in increased expression of GAD1 protein CTD PMID:18312583 , PMID:28555334 (S)-nicotine decreases methylation EXP 6480464 Nicotine results in decreased methylation of GAD1 promoter CTD PMID:28555334 (S)-nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of GAD1 mRNA] CTD PMID:28555334 17beta-estradiol increases expression ISO RGD:730853 6480464 Estradiol results in increased expression of GAD1 mRNA CTD PMID:24758408 , PMID:31614463 17beta-estradiol multiple interactions ISO RGD:730853 6480464 EGF protein promotes the reaction [Estradiol results in increased expression of GAD1 mRNA] CTD PMID:24758408 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:730853 6480464 2 more ... CTD PMID:19095052 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:27291303 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GAD1 mRNA CTD PMID:12060831 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10615 6480464 Tetrachlorodibenzodioxin affects the expression of GAD1 mRNA CTD PMID:24680724 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:730853 6480464 Tetrachlorodibenzodioxin results in increased expression of GAD1 mRNA CTD PMID:20106945 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:730853 6480464 Tetrachlorodibenzodioxin results in decreased expression of GAD1 mRNA CTD PMID:21296121 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2-methyl-6-(phenylethynyl)pyridine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Levodopa promotes the reaction [Oxidopamine results in increased expression of GAD1 mRNA]] CTD PMID:19660528 3-Acetylpyridine increases expression EXP 6480464 3-acetylpyridine results in increased expression of GAD1 mRNA CTD PMID:8774452 3-Acetylpyridine multiple interactions EXP 6480464 Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA] more ... CTD PMID:8774452 3-mercaptopropanoic acid decreases activity EXP 6480464 3-Mercaptopropionic Acid results in decreased activity of GAD1 protein CTD PMID:4154755 3-mercaptopropanoic acid multiple interactions ISO RGD:730853 6480464 3-Mercaptopropionic Acid binds to and results in decreased activity of GAD1 protein CTD PMID:35151785 4,4'-sulfonyldiphenol decreases methylation ISO RGD:10615 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of GAD1 exon, bis(4-hydroxyphenyl)sulfone results in decreased methylation of GAD1 promoter CTD PMID:33297965 4,4'-sulfonyldiphenol decreases methylation ISO RGD:730853 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of GAD1 gene CTD PMID:31601247 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 Decitabine inhibits the reaction [bisphenol A results in decreased expression of GAD1 mRNA] CTD PMID:23791455 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of GAD1 mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of GAD1 mRNA CTD PMID:30047161 6-propyl-2-thiouracil multiple interactions EXP 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of GAD1 mRNA CTD PMID:31068541 acetic acid increases expression ISO RGD:730853 6480464 Acetic Acid results in increased expression of GAD1 mRNA CTD PMID:17065238 acrylamide decreases expression ISO RGD:730853 6480464 Acrylamide results in decreased expression of GAD1 mRNA CTD PMID:32763439 aldehydo-D-glucose multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 all-trans-retinoic acid decreases expression ISO RGD:730853 6480464 Tretinoin results in decreased expression of GAD1 mRNA CTD PMID:21934132 all-trans-retinoic acid increases expression ISO RGD:10615 6480464 Tretinoin results in increased expression of GAD1 mRNA, Tretinoin results in increased expression of GAD1 protein alternative form CTD PMID:11841568 , PMID:22466603 amitrole multiple interactions EXP 6480464 Amitrole promotes the reaction [Sodium Chloride, Dietary results in decreased expression of GAD1 protein] CTD PMID:25891026 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of GAD1 mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GAD1 mRNA CTD PMID:16483693 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of GAD1 mRNA, Amphetamine results in increased expression of GAD1 protein CTD PMID:14725721 , PMID:18312583 amphetamine affects expression ISO RGD:10615 6480464 Amphetamine affects the expression of GAD1 protein CTD PMID:19059431 amphetamine increases expression ISO RGD:10615 6480464 Amphetamine results in increased expression of GAD1 mRNA CTD PMID:23660488 amphetamine multiple interactions EXP 6480464 Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA], Propranolol inhibits the reaction [Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]] CTD PMID:8774452 apocynin multiple interactions ISO RGD:10615 6480464 acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein] CTD PMID:18063801 Aroclor 1254 multiple interactions EXP 6480464 [aroclor 1242 co-treated with aroclor 1248 co-treated with Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1260] results in decreased expression of GAD1 protein CTD PMID:17324953 belinostat increases expression ISO RGD:730853 6480464 belinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 belinostat multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 benzo[a]pyrene increases expression ISO RGD:730853 6480464 Benzo(a)pyrene results in increased expression of GAD1 mRNA CTD PMID:20106945 more ... benzo[a]pyrene increases methylation ISO RGD:730853 6480464 Benzo(a)pyrene results in increased methylation of GAD1 promoter CTD PMID:27901495 bis(2-chloroethyl) sulfide increases expression ISO RGD:10615 6480464 Mustard Gas results in increased expression of GAD1 mRNA CTD PMID:15674844 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:730853 6480464 Diethylhexyl Phthalate results in decreased expression of GAD1 mRNA CTD PMID:31163220 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of GAD1 mRNA CTD PMID:25181051 , PMID:26950200 bisphenol A decreases expression ISO RGD:10615 6480464 bisphenol A results in decreased expression of GAD1 mRNA CTD PMID:32156529 bisphenol A multiple interactions ISO RGD:730853 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GAD1 gene CTD PMID:31601247 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of H2AC7 mRNA CTD PMID:25181051 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GAD1 gene CTD PMID:28505145 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GAD1 mRNA CTD PMID:18180321 , PMID:23791455 bisphenol A multiple interactions EXP 6480464 decitabine inhibits the reaction [bisphenol A results in decreased expression of GAD1 mRNA] CTD PMID:23791455 butanal increases expression ISO RGD:730853 6480464 butyraldehyde results in increased expression of GAD1 mRNA CTD PMID:26079696 cadmium dichloride increases expression ISO RGD:730853 6480464 Cadmium Chloride results in increased expression of GAD1 mRNA CTD PMID:12160620 caffeine increases expression EXP 6480464 Caffeine results in increased expression of GAD1 mRNA, Caffeine results in increased expression of GAD1 protein CTD PMID:35917217 cannabidiol multiple interactions EXP 6480464 Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 carbamazepine affects expression ISO RGD:730853 6480464 Carbamazepine affects the expression of GAD1 mRNA CTD PMID:25979313 chaetocin multiple interactions EXP 6480464 chaetocin affects the reaction [Dronabinol affects the expression of GAD1 mRNA] CTD PMID:29022873 , PMID:29481316 chlorpromazine decreases methylation ISO RGD:10615 6480464 Chlorpromazine results in decreased methylation of GAD1 promoter CTD PMID:19110320 chlorpromazine multiple interactions ISO RGD:10615 6480464 Valproic Acid promotes the reaction [Chlorpromazine results in decreased methylation of GAD1 promoter] CTD PMID:19110320 chlorpyrifos increases expression ISO RGD:10615 6480464 Chlorpyrifos results in increased expression of GAD1 mRNA CTD PMID:36113784 chlorpyrifos affects binding ISO RGD:730853 6480464 Chlorpyrifos binds to [GAD1 protein binds to Pyridoxal Phosphate], Chlorpyrifos binds to GAD1 protein CTD PMID:35151785 cisplatin increases expression ISO RGD:730853 6480464 Cisplatin results in increased expression of GAD1 mRNA CTD PMID:27392435 cisplatin multiple interactions ISO RGD:730853 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of GAD1 mRNA CTD PMID:27392435 clenbuterol multiple interactions EXP 6480464 Clenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA] more ... CTD PMID:8774452 clozapine increases expression ISO RGD:730853 6480464 Clozapine results in increased expression of GAD1 mRNA CTD PMID:17942719 clozapine increases expression EXP 6480464 Clozapine results in increased expression of GAD1 mRNA CTD PMID:12887421 more ... clozapine decreases methylation ISO RGD:10615 6480464 Clozapine results in decreased methylation of GAD1 promoter CTD PMID:18757738 clozapine multiple interactions ISO RGD:10615 6480464 Clozapine promotes the reaction [KMT2A protein binds to GAD1 promoter], Valproic Acid promotes the reaction [Clozapine results in decreased methylation of GAD1 promoter] CTD PMID:17942719 , PMID:18757738 cobalt dichloride decreases expression ISO RGD:730853 6480464 cobaltous chloride results in decreased expression of GAD1 mRNA CTD PMID:22941251 cobalt dichloride decreases expression ISO RGD:10615 6480464 cobaltous chloride results in decreased expression of GAD1 protein CTD PMID:29107683 cocaine decreases expression ISO RGD:730853 6480464 Cocaine results in decreased expression of GAD1 mRNA CTD PMID:12629581 cocaine increases expression EXP 6480464 Cocaine results in increased expression of GAD1 protein CTD PMID:15295023 , PMID:18611417 corticosterone multiple interactions ISO RGD:10615 6480464 GAD1 affects the reaction [2 more ... CTD PMID:21219938 corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of GAD1 mRNA CTD PMID:32437893 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of GAD1 mRNA CTD PMID:26577399 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA] CTD PMID:23267840 cyclosporin A decreases expression ISO RGD:730853 6480464 Cyclosporine results in decreased expression of GAD1 mRNA CTD PMID:27989131 cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of GAD1 mRNA, cypermethrin results in decreased expression of GAD1 protein CTD PMID:26115703 cyproconazole decreases expression EXP 6480464 cyproconazole results in decreased expression of GAD1 mRNA CTD PMID:25182419 D-glucose multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of GAD1 mRNA, Dexamethasone results in increased expression of GAD1 protein CTD PMID:31518422 , PMID:32445661 dexamethasone multiple interactions EXP 6480464 BDNF protein inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA], Mifepristone inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA] CTD PMID:31518422 , PMID:32445661 dextran sulfate multiple interactions ISO RGD:10615 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GAD1 mRNA CTD PMID:29950665 diazepam decreases expression EXP 6480464 Diazepam results in decreased expression of GAD1 mRNA CTD PMID:15802192 diazinon affects binding ISO RGD:730853 6480464 Diazinon binds to [GAD1 protein binds to Pyridoxal Phosphate], Diazinon binds to GAD1 protein CTD PMID:35151785 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of GAD1 mRNA CTD PMID:15620428 dihydro-beta-erythroidine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of GAD1 mRNA] CTD PMID:28555334 diisopropyl fluorophosphate affects binding ISO RGD:730853 6480464 Isoflurophate binds to [GAD1 protein binds to Pyridoxal Phosphate], Isoflurophate binds to GAD1 protein CTD PMID:35151785 dimethyl sulfoxide increases expression ISO RGD:730853 6480464 Dimethyl Sulfoxide results in increased expression of GAD1 mRNA CTD PMID:17065238 dioxygen multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 dioxygen multiple interactions ISO RGD:10615 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] more ... CTD PMID:29107683 dioxygen decreases expression ISO RGD:10615 6480464 Oxygen deficiency results in decreased expression of GAD1 mRNA CTD PMID:29107683 dioxygen increases expression ISO RGD:730853 6480464 Oxygen deficiency results in increased expression of GAD1 mRNA CTD PMID:26516004 disodium selenite decreases expression ISO RGD:10615 6480464 Sodium Selenite results in decreased expression of GAD1 mRNA CTD PMID:23274088 dizocilpine maleate multiple interactions ISO RGD:10615 6480464 Dizocilpine Maleate inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] CTD PMID:29107683 dorsomorphin multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression ISO RGD:730853 6480464 Doxorubicin results in increased expression of GAD1 mRNA CTD PMID:17065238 entinostat multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 entinostat increases expression ISO RGD:730853 6480464 entinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 ethanol increases expression EXP 6480464 Ethanol results in increased expression of GAD1 mRNA CTD PMID:15729141 , PMID:32437893 ethanol multiple interactions ISO RGD:10615 6480464 Ethanol affects the expression of and affects the splicing of GAD1 mRNA CTD PMID:30319688 ethanol increases expression ISO RGD:10615 6480464 Ethanol results in increased expression of GAD1 protein CTD PMID:29044621 eticlopride(1+) increases expression EXP 6480464 eticlopride results in increased expression of GAD1 mRNA CTD PMID:15044549 fenamidone decreases expression ISO RGD:10615 6480464 fenamidone results in decreased expression of GAD1 mRNA CTD PMID:27029645 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of GAD1 mRNA CTD PMID:17033635 fluvoxamine multiple interactions EXP 6480464 [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein CTD PMID:15967061 folic acid decreases expression ISO RGD:10615 6480464 Folic Acid results in decreased expression of GAD1 protein CTD PMID:26547318 fonofos increases methylation ISO RGD:730853 6480464 Fonofos results in increased methylation of GAD1 promoter CTD PMID:22847954 fulvestrant multiple interactions ISO RGD:730853 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GAD1 gene CTD PMID:31601247 furan increases methylation EXP 6480464 furan results in increased methylation of GAD1 gene CTD PMID:22079235 furosemide decreases expression EXP 6480464 Furosemide results in decreased expression of GAD1 mRNA CTD PMID:14596865 gamma-aminobutyric acid increases chemical synthesis ISO RGD:730853 6480464 GAD1 protein results in increased chemical synthesis of gamma-Aminobutyric Acid CTD PMID:15571623 gamma-aminobutyric acid decreases expression EXP 6480464 gamma-Aminobutyric Acid results in decreased expression of GAD1 mRNA CTD PMID:26924987 genistein decreases expression EXP 6480464 Genistein results in decreased expression of GAD1 mRNA CTD PMID:21782745 glucose multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 glyphosate affects binding ISO RGD:730853 6480464 glyphosate binds to [GAD1 protein binds to Pyridoxal Phosphate], glyphosate binds to GAD1 protein CTD PMID:35151785 haloperidol multiple interactions EXP 6480464 [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein CTD PMID:15967061 haloperidol increases expression EXP 6480464 Haloperidol results in increased expression of GAD1 mRNA CTD PMID:12887421 more ... haloperidol decreases expression EXP 6480464 Haloperidol results in decreased expression of GAD1 mRNA, Haloperidol results in decreased expression of GAD1 protein CTD PMID:14519413 , PMID:19359144 hydrogen peroxide decreases response to substance ISO RGD:730853 6480464 GAD1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:15369822 hydrogen peroxide affects expression ISO RGD:730853 6480464 Hydrogen Peroxide affects the expression of GAD1 mRNA CTD PMID:20044591 kainic acid increases expression EXP 6480464 Kainic Acid results in increased expression of GAD1 mRNA CTD PMID:16797850 ketamine multiple interactions ISO RGD:10615 6480464 acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein] CTD PMID:18063801 ketamine increases expression ISO RGD:10615 6480464 Ketamine results in increased expression of GAD1 mRNA CTD PMID:23660488 ketamine decreases expression ISO RGD:10615 6480464 Ketamine results in decreased expression of GAD1 CTD PMID:18063801 ketoconazole decreases expression ISO RGD:10615 6480464 Ketoconazole results in decreased expression of GAD1 mRNA CTD PMID:31099283 L-glutamic acid multiple interactions ISO RGD:730853 6480464 [GAD1 protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Glutamic Acid CTD PMID:35151785 L-methionine decreases expression ISO RGD:10615 6480464 Methionine results in decreased expression of GAD1 more ... CTD PMID:15671176 more ... L-methionine multiple interactions ISO RGD:10615 6480464 Methionine promotes the reaction [MECP2 binds to GAD1 promoter], Valproic Acid inhibits the reaction [Methionine results in decreased expression of GAD1 protein] CTD PMID:16113080 , PMID:20442623 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of GAD1 protein CTD PMID:15149801 lead(0) affects expression ISO RGD:730853 6480464 Lead affects the expression of GAD1 mRNA CTD PMID:28903495 leflunomide increases expression ISO RGD:730853 6480464 leflunomide results in increased expression of GAD1 mRNA CTD PMID:28988120 lipoic acid multiple interactions EXP 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of GAD1 mRNA CTD PMID:31068541 malathion affects binding ISO RGD:730853 6480464 Malathion binds to [GAD1 protein binds to Pyridoxal Phosphate], Malathion binds to GAD1 protein CTD PMID:35151785 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of GAD1 mRNA CTD PMID:12106697 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein] CTD PMID:35085591 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of GAD1 mRNA CTD PMID:30047161 methotrexate affects response to substance ISO RGD:730853 6480464 GAD1 protein affects the susceptibility to Methotrexate CTD PMID:16217747 methotrexate decreases expression ISO RGD:730853 6480464 Methotrexate results in decreased expression of GAD1 mRNA CTD PMID:24449571 methylazoxymethanol decreases expression EXP 6480464 methylazoxymethanol results in decreased expression of GAD1 mRNA CTD PMID:23932495 methylmercury chloride decreases expression ISO RGD:10615 6480464 methylmercuric chloride results in decreased expression of GAD1 mRNA CTD PMID:21385734 methylmercury chloride multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 methylmercury chloride increases expression ISO RGD:730853 6480464 methylmercuric chloride results in increased expression of GAD1 mRNA CTD PMID:23179753 , PMID:26272509 mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA] CTD PMID:32445661 Mipafox affects binding ISO RGD:730853 6480464 mipafox binds to [GAD1 protein binds to Pyridoxal Phosphate], mipafox binds to GAD1 protein CTD PMID:35151785 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of GAD1 mRNA CTD PMID:19733649 monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of GAD1 protein CTD PMID:19733649 morphine increases expression EXP 6480464 Morphine results in increased expression of GAD1 mRNA CTD PMID:15673448 , PMID:18312583 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:10615 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] CTD PMID:29107683 N-ethylmaleimide decreases activity ISO RGD:730853 6480464 Ethylmaleimide results in decreased activity of GAD1 protein CTD PMID:15836621 nickel sulfate increases expression ISO RGD:730853 6480464 nickel sulfate results in increased expression of GAD1 mRNA CTD PMID:22714537 nicotine increases expression EXP 6480464 Nicotine results in increased expression of GAD1 mRNA, Nicotine results in increased expression of GAD1 protein CTD PMID:18312583 , PMID:28555334 nicotine decreases methylation EXP 6480464 Nicotine results in decreased methylation of GAD1 promoter CTD PMID:28555334 nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of GAD1 mRNA] CTD PMID:28555334 Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of GAD1 mRNA CTD PMID:15620428 O-methyleugenol increases expression ISO RGD:730853 6480464 methyleugenol results in increased expression of GAD1 mRNA CTD PMID:32234424 olanzapine decreases expression EXP 6480464 olanzapine results in decreased expression of GAD1 mRNA, olanzapine results in decreased expression of GAD1 protein CTD PMID:14519413 , PMID:19359144 oxidopamine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Levodopa promotes the reaction [Oxidopamine results in increased expression of GAD1 mRNA]] more ... CTD PMID:17241287 , PMID:19660528 oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of GAD1 mRNA CTD PMID:12077209 more ... panobinostat multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:730853 6480464 panobinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 paracetamol affects expression ISO RGD:10615 6480464 Acetaminophen affects the expression of GAD1 mRNA CTD PMID:17562736 paraoxon affects binding ISO RGD:730853 6480464 Paraoxon binds to [GAD1 protein binds to Pyridoxal Phosphate], Paraoxon binds to GAD1 protein CTD PMID:35151785 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of GAD1 mRNA CTD PMID:17493592 parathion increases methylation ISO RGD:730853 6480464 Parathion results in increased methylation of GAD1 promoter CTD PMID:22847954 pentanal increases expression ISO RGD:730853 6480464 pentanal results in increased expression of GAD1 mRNA CTD PMID:26079696 pentane-2,3-dione decreases expression EXP 6480464 2, 3-pentanedione results in decreased expression of GAD1 mRNA CTD PMID:25710175 perfluorooctanoic acid decreases expression ISO RGD:10615 6480464 perfluorooctanoic acid results in decreased expression of GAD1 mRNA CTD PMID:20118188 perfluorooctanoic acid increases expression ISO RGD:730853 6480464 perfluorooctanoic acid results in increased expression of GAD1 mRNA CTD PMID:23978341 phenylmercury acetate decreases expression ISO RGD:730853 6480464 Phenylmercuric Acetate results in decreased expression of GAD1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GAD1 mRNA CTD PMID:27188386 picrotoxin increases expression EXP 6480464 Picrotoxin results in increased expression of GAD1 mRNA CTD PMID:15170462 poly(I:C) multiple interactions EXP 6480464 Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 poly(I:C) decreases expression EXP 6480464 Poly I-C results in decreased expression of GAD1 protein CTD PMID:31202911 propanal increases expression ISO RGD:730853 6480464 propionaldehyde results in increased expression of GAD1 mRNA CTD PMID:26079696 propranolol multiple interactions EXP 6480464 Propranolol inhibits the reaction [Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]], Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]] CTD PMID:8774452 pyridoxal 5'-phosphate affects binding ISO RGD:730853 6480464 Chlorpyrifos binds to [GAD1 protein binds to Pyridoxal Phosphate] more ... CTD PMID:15686475 , PMID:35151785 pyridoxal 5'-phosphate multiple interactions ISO RGD:730853 6480464 [GAD1 protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Glutamic Acid CTD PMID:35151785 pyridoxal 5'-phosphate decreases activity EXP 6480464 Pyridoxal Phosphate results in decreased activity of GAD1 protein CTD PMID:7463050 pyridoxal 5'-phosphate increases activity ISO RGD:10615 6480464 Pyridoxal Phosphate results in increased activity of GAD1 protein CTD PMID:171340 quercetin increases expression ISO RGD:730853 6480464 Quercetin results in increased expression of GAD1 mRNA CTD PMID:21632981 raloxifene multiple interactions ISO RGD:730853 6480464 [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA CTD PMID:19059307 reserpine increases expression EXP 6480464 Reserpine results in increased expression of GAD1 mRNA CTD PMID:8774452 reserpine multiple interactions EXP 6480464 Clenbuterol inhibits the reaction [Reserpine results in increased expression of GAD1 mRNA] CTD PMID:8774452 sarin affects binding ISO RGD:730853 6480464 Sarin binds to [GAD1 protein binds to Pyridoxal Phosphate], Sarin binds to GAD1 protein CTD PMID:35151785 SB 431542 multiple interactions ISO RGD:730853 6480464 [FGF2 protein co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 , PMID:32733202 sodium arsenite increases expression ISO RGD:730853 6480464 sodium arsenite results in increased expression of GAD1 mRNA CTD PMID:22714537 , PMID:29301061 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GAD1 mRNA CTD PMID:20376865 Soman affects binding ISO RGD:730853 6480464 Soman binds to [GAD1 protein binds to Pyridoxal Phosphate], Soman binds to GAD1 protein CTD PMID:35151785 sotorasib multiple interactions ISO RGD:730853 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAD1 mRNA CTD PMID:36139627 streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein more ... CTD PMID:23267840 , PMID:35085591 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of GAD1 mRNA CTD PMID:23267840 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of GAD1 mRNA CTD PMID:30047161 sulpiride decreases methylation ISO RGD:10615 6480464 Sulpiride results in decreased methylation of GAD1 promoter CTD PMID:18757738 sulpiride multiple interactions ISO RGD:10615 6480464 Valproic Acid promotes the reaction [Sulpiride results in decreased methylation of GAD1 promoter] CTD PMID:18757738 tamoxifen multiple interactions ISO RGD:730853 6480464 [Tamoxifen co-treated with ESR2 protein] results in increased expression of GAD1 mRNA CTD PMID:19059307 terbufos increases methylation ISO RGD:730853 6480464 terbufos results in increased methylation of GAD1 promoter CTD PMID:22847954 testosterone increases expression EXP 6480464 Testosterone results in increased expression of GAD1 mRNA CTD PMID:21281643 titanium dioxide multiple interactions ISO RGD:10615 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GAD1 mRNA CTD PMID:29950665 toluene affects expression EXP 6480464 Toluene affects the expression of GAD1 mRNA CTD PMID:21827849 trametinib multiple interactions ISO RGD:730853 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAD1 mRNA CTD PMID:36139627 trichostatin A increases expression ISO RGD:730853 6480464 trichostatin A results in increased expression of GAD1 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of GAD1 mRNA CTD PMID:33078273 triptonide increases expression ISO RGD:10615 6480464 triptonide results in increased expression of GAD1 mRNA CTD PMID:33045310 valproic acid multiple interactions ISO RGD:10615 6480464 Valproic Acid inhibits the reaction [MECP2 binds to GAD1 promoter] more ... CTD PMID:16113080 more ... valproic acid decreases expression ISO RGD:730853 6480464 Valproic Acid results in decreased expression of GAD1 mRNA CTD PMID:34742744 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GAD1 mRNA CTD PMID:34779009 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of GAD1 mRNA, Valproic Acid results in decreased expression of GAD1 protein CTD PMID:30404997 , PMID:32428529 valproic acid decreases expression ISO RGD:10615 6480464 Valproic Acid results in decreased expression of GAD1 mRNA CTD PMID:24896083 valproic acid affects expression ISO RGD:730853 6480464 Valproic Acid affects the expression of GAD1 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:730853 6480464 Valproic Acid results in increased expression of GAD1 mRNA CTD PMID:23179753 more ... valproic acid decreases methylation ISO RGD:10615 6480464 Valproic Acid results in decreased methylation of GAD1 promoter CTD PMID:20716949 valproic acid increases expression ISO RGD:10615 6480464 Valproic Acid results in increased expression of GAD1 mRNA CTD PMID:15737665 vigabatrin increases expression EXP 6480464 Vigabatrin results in increased expression of GAD1 protein CTD PMID:11673025 vorinostat increases expression ISO RGD:730853 6480464 vorinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO RGD:730853 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 VX nerve agent affects binding ISO RGD:730853 6480464 VX binds to [GAD1 protein binds to Pyridoxal Phosphate], VX binds to GAD1 protein CTD PMID:35151785 zinc atom increases expression ISO RGD:730853 6480464 Zinc deficiency results in increased expression of GAD1 mRNA CTD PMID:18356318 zinc(0) increases expression ISO RGD:730853 6480464 Zinc deficiency results in increased expression of GAD1 mRNA CTD PMID:18356318