Strain Report - Rat Genome Database

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Strain: SS-Tgfb1em3Mcwi

Symbol: SS-Tgfb1em3Mcwi
Strain: SS-Tgfb1em3
Substrain: Mcwi
RGD ID: 5131989
Citation ID: RRID:RGD_5131989
Ontology ID: RS:0002601
Alleles: Tgfb1em3Mcwi
Also Known As: SS-Tgfb1em3Mcwi; SS-Tgfb1^[em3Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CTGCTCCCACTCCCGTGGcttctAGTGCTGACGCCCGG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 22-bp frameshift deletion in exon 3.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2181,196,532 - 81,212,848RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0182,480,875 - 82,497,196RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0183,742,151 - 83,758,472RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4180,894,705 - 80,911,020RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Heterozygous knockout of transforming growth factor-ß1 protects Dahl S rats against high salt-induced renal injury. Chen CC, etal., Physiol Genomics. 2013 Feb 4;45(3):110-8. doi: 10.1152/physiolgenomics.00119.2012. Epub 2012 Dec 18.
2. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-26 SS-Tgfb1em3Mcwi    SS-Tgfb1em3Mcwi    Symbol updated 68687 APPROVED
2014-03-26 SS-Tgfb1em3Mcwi    SS-Tgfb1em3Mcwi    Symbol updated 68687 APPROVED
2014-03-26 SS-Tgfb1em3Mcwi    SS-Tgfb1em3Mcwi    Name updated 68913 APPROVED
2014-03-26 SS-Tgfb1em3Mcwi    SS-Tgfb1em3Mcwi    Name updated 68913 APPROVED
2013-08-13 SS-Tgfb1em3Mcwi    SS-Tgfb1em3Mcwi    Name updated 68913 APPROVED
2013-08-13 SS-Tgfb1em3Mcwi    SS-Tgfb1em3Mcwi    Name updated 68913 APPROVED