(+)-catechin decreases activity ISO RGD:1350018 6480464 Catechin results in decreased activity of UGT1A1 protein CTD PMID:35868516 (+)-taxifolin multiple interactions ISO RGD:1350018 6480464 AHR gene mutant form inhibits the reaction [taxifolin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 (+)-taxifolin increases expression ISO RGD:1350018 6480464 taxifolin results in increased expression of UGT1A1 mRNA CTD PMID:29584932 (1->4)-beta-D-glucan multiple interactions ISO RGD:11476 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UGT1A1 mRNA CTD PMID:36331819 (5Z,8Z,11Z,13E)-15-HETE increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 15-hydroxy-5 more ... CTD PMID:15231852 (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 (S)-naringenin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of naringenin CTD PMID:14557274 (S)-naringenin increases expression ISO RGD:11476 6480464 naringenin results in increased expression of UGT1A1 mRNA CTD PMID:31621310 (Z)-ligustilide increases expression ISO RGD:11476 6480464 ligustilide results in increased expression of UGT1A1 protein CTD PMID:23441843 (Z)-ligustilide increases expression ISO RGD:1350018 6480464 ligustilide results in increased expression of UGT1A1 mRNA CTD PMID:30243965 1,4-dioxane decreases expression ISO RGD:11476 6480464 1, 4-dioxane results in decreased expression of UGT1A1 mRNA CTD PMID:33693819 1-Hydroxypyrene increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 1-hydroxypyrene CTD PMID:15802387 1-naphthyl isothiocyanate decreases expression ISO RGD:11476 6480464 1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA, 1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein CTD PMID:32976922 1-naphthyl isothiocyanate multiple interactions EXP 6480464 ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA] more ... CTD PMID:32198087 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA, 1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein CTD PMID:32198087 1-naphthyl isothiocyanate increases expression ISO RGD:11476 6480464 1-Naphthylisothiocyanate results in increased expression of UGT1A1 protein CTD PMID:28549656 1-naphthyl isothiocyanate multiple interactions ISO RGD:11476 6480464 Chenodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA] more ... CTD PMID:32976922 17alpha-ethynylestradiol multiple interactions ISO RGD:1350018 6480464 chrysin promotes the reaction [UGT1A1 protein affects the glucuronidation of Ethinyl Estradiol] CTD PMID:10950852 17alpha-ethynylestradiol decreases expression ISO RGD:11476 6480464 Ethinyl Estradiol results in decreased expression of UGT1A1 mRNA CTD PMID:27818225 17alpha-ethynylestradiol increases glucuronidation EXP 6480464 UGT1A1 protein results in increased glucuronidation of Ethinyl Estradiol CTD PMID:15921999 17alpha-ethynylestradiol decreases glucuronidation ISO RGD:1350018 6480464 UGT1A1 gene mutant form results in decreased glucuronidation of Ethinyl Estradiol analog CTD PMID:17898154 17alpha-ethynylestradiol affects metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein affects the metabolism of Ethinyl Estradiol CTD PMID:15286053 17alpha-ethynylestradiol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Ethinyl Estradiol, UGT1A1 protein results in increased glucuronidation of Ethinyl Estradiol analog CTD PMID:12756209 , PMID:17898154 17beta-estradiol decreases activity ISO RGD:1350018 6480464 Estradiol results in decreased activity of UGT1A1 protein CTD PMID:15378558 17beta-estradiol increases glucuronidation EXP 6480464 UGT1A1 protein results in increased glucuronidation of Estradiol CTD PMID:31128210 17beta-estradiol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Estradiol, UGT1A1 protein results in increased glucuronidation of Estradiol analog CTD PMID:15117964 more ... 17beta-estradiol multiple interactions ISO RGD:1350018 6480464 [Cycloheximide co-treated with Estradiol] results in decreased expression of UGT1A1 mRNA more ... CTD PMID:15072547 more ... 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of UGT1A1 mRNA CTD PMID:22389237 , PMID:24777823 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of UGT1A1 mRNA CTD PMID:31119341 17beta-estradiol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] more ... CTD PMID:22389237 more ... 17beta-estradiol decreases expression ISO RGD:1350018 6480464 Estradiol results in decreased expression of UGT1A1 mRNA CTD PMID:15072547 , PMID:17982697 17beta-estradiol decreases glucuronidation ISO RGD:1350018 6480464 UGT1A1 gene mutant form results in decreased glucuronidation of Estradiol analog CTD PMID:17898154 17beta-estradiol 3-benzoate increases methylation EXP 6480464 estradiol 3-benzoate results in increased methylation of UGT1A1 promoter CTD PMID:27415467 2',4,4',6'-tetrahydroxychalcone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of naringenin chalcone CTD PMID:14557274 2',5'-Dihydroxychalcone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 2', 5'-dihydroxychalcone CTD PMID:14557274 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:11476 6480464 [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2 more ... CTD PMID:23756648 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:11476 6480464 2 more ... CTD PMID:17964624 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:20056577 , PMID:32679240 2,3,4,7,8-Pentachlorodibenzofuran increases expression ISO RGD:11476 6480464 2 more ... CTD PMID:24713691 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1350018 6480464 [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of UGT1A1 mRNA more ... CTD PMID:12566446 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:11476 6480464 Tetrachlorodibenzodioxin affects the expression of UGT1A1 mRNA CTD PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of UGT1A1 mRNA CTD PMID:16054898 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:11476 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA more ... CTD PMID:19144771 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:11476 6480464 [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of UGT1A1 mRNA more ... CTD PMID:16155002 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1350018 6480464 Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA, Tetrachlorodibenzodioxin results in increased expression of UGT1A1 protein CTD PMID:16155002 more ... 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO RGD:1350018 6480464 Tetrachlorodibenzodioxin results in increased activity of UGT1A1 protein CTD PMID:16155002 , PMID:16399344 2,3,7,8-tetrachlorodibenzodioxine increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Tetrachlorodibenzodioxin metabolite CTD PMID:15258113 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:11476 6480464 2 more ... CTD PMID:24713691 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of UGT1A1 mRNA CTD PMID:21346803 2,4,6-Triphenyl-1-hexene decreases expression ISO RGD:11476 6480464 2 more ... CTD PMID:18560529 2,4-Dihydroxychalcone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 2', 4'-dihydroxychalcone CTD PMID:14557274 2-hydroxy-17beta-estradiol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 2-hydroxyestradiol CTD PMID:14871858 , PMID:15117964 2-hydroxyestrone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 2-hydroxyestrone CTD PMID:15117964 2-methoxy-17beta-estradiol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 2-Methoxyestradiol CTD PMID:15117964 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of UGT1A1 mRNA CTD PMID:20650352 20-HETE increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 20-hydroxy-5 more ... CTD PMID:15231852 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:19692669 , PMID:20959002 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:11476 6480464 3 more ... CTD PMID:19144771 , PMID:26770886 3,3',5,5'-tetrabromobisphenol A affects expression EXP 6480464 tetrabromobisphenol A affects the expression of UGT1A1 mRNA CTD PMID:26988606 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of UGT1A1 mRNA CTD PMID:28300664 3,3',5-triiodo-L-thyronine decreases expression EXP 6480464 Triiodothyronine results in decreased expression of UGT1A1 mRNA CTD PMID:11299074 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 Vitamin A inhibits the reaction [Triiodothyronine results in decreased expression of UGT1A1 mRNA] CTD PMID:11299074 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine increases expression ISO RGD:1350018 6480464 3 more ... CTD PMID:23810796 3-Hydroxybenzo[a]pyrene increases glucuronidation EXP 6480464 UGT1A1 protein results in increased glucuronidation of 3-hydroxybenzo(a)pyrene CTD PMID:1435739 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases expression ISO RGD:1350018 6480464 2-amino-3-methylimidazo(4, 5-f)quinoline results in increased expression of UGT1A1 mRNA CTD PMID:31542801 3-methylcholanthrene increases expression ISO RGD:1350018 6480464 Methylcholanthrene results in increased expression of UGT1A1 mRNA CTD PMID:19118567 , PMID:33811995 3-methylcholanthrene multiple interactions ISO RGD:1350018 6480464 Oxygen deficiency inhibits the reaction [Methylcholanthrene results in increased expression of UGT1A1 mRNA] CTD PMID:33811995 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of UGT1A1 mRNA, Methylcholanthrene results in increased expression of UGT1A1 protein CTD PMID:1435739 , PMID:18203689 3-methylcholanthrene multiple interactions EXP 6480464 [Methylcholanthrene results in increased expression of UGT1A1 protein] which results in increased glucuronidation of 3 more ... CTD PMID:1435739 4,4'-sulfonyldiphenol increases expression ISO RGD:1350018 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of UGT1A1 CTD PMID:31207516 4,4'-sulfonyldiphenol affects methylation ISO RGD:11476 6480464 bis(4-hydroxyphenyl)sulfone affects the methylation of UGT1A1 gene CTD PMID:31683443 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 1-(4-hydroxyphenyl)-1, 2-diphenyl-1-butene CTD PMID:29285606 4-hydroxyestrone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 4-hydroxyestrone CTD PMID:15117964 4-hydroxyphenytoin multiple interactions ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of and results in decreased activity of hydroxyphenytoin CTD PMID:15855726 4-methylumbelliferone multiple interactions ISO RGD:1350018 6480464 [UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide more ... CTD PMID:15378558 more ... 4-methylumbelliferone increases metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein results in increased metabolism of Hymecromone CTD PMID:31812603 4-methylumbelliferone increases activity ISO RGD:1350018 6480464 Hymecromone results in increased activity of UGT1A1 protein CTD PMID:26875642 4-methylumbelliferone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Hymecromone CTD PMID:15378558 more ... 4-methylumbelliferone beta-D-glucuronide multiple interactions ISO RGD:1350018 6480464 [UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide more ... CTD PMID:31812603 , PMID:33290829 4-nitrophenol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 4-nitrophenol CTD PMID:15802387 5,7-dihydroxy-4'-methoxyflavone increases expression ISO RGD:11476 6480464 acacetin results in increased expression of UGT1A1 mRNA CTD PMID:31621310 5,7-dihydroxy-4'-methoxyflavone increases expression ISO RGD:1350018 6480464 acacetin results in increased expression of UGT1A1 mRNA CTD PMID:31621310 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1350018 6480464 HNF1A protein promotes the reaction [Decitabine results in increased expression of UGT1A1 mRNA] CTD PMID:23401472 5-aza-2'-deoxycytidine increases expression ISO RGD:1350018 6480464 Decitabine results in increased expression of UGT1A1 mRNA CTD PMID:23401472 5-fluorouracil multiple interactions ISO RGD:1350018 6480464 UGT1A1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with irinotecan] CTD PMID:18797458 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression ISO RGD:1350018 6480464 Omeprazole results in increased expression of UGT1A1 mRNA CTD PMID:19118567 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of UGT1A1 mRNA CTD PMID:19483382 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression EXP 6480464 Omeprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 5-methoxypsoralen multiple interactions EXP 6480464 5-methoxypsoralen promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] CTD PMID:17599282 5-methoxypsoralen multiple interactions ISO RGD:1350018 6480464 5-methoxypsoralen promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] CTD PMID:17599282 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of UGT1A1 mRNA CTD PMID:19483382 8-Epidiosbulbin E acetate decreases expression ISO RGD:11476 6480464 8-epidiosbulbin E acetate results in decreased expression of UGT1A1 mRNA CTD PMID:31626840 9-cis-retinoic acid increases expression EXP 6480464 Alitretinoin results in increased expression of UGT1A1 mRNA CTD PMID:14620509 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of UGT1A1 mRNA CTD PMID:31881176 acetylsalicylic acid increases response to substance EXP 6480464 UGT1A1 gene mutant form results in increased susceptibility to Aspirin, UGT1A1 protein mutant form results in increased susceptibility to Aspirin CTD PMID:3864191 , PMID:6776978 afimoxifene decreases expression ISO RGD:1350018 6480464 afimoxifene results in decreased expression of UGT1A1 mRNA CTD PMID:15072547 aflatoxin B1 increases activity EXP 6480464 Aflatoxin B1 results in increased activity of UGT1A1 protein CTD PMID:20015472 aflatoxin B1 decreases methylation ISO RGD:1350018 6480464 Aflatoxin B1 results in decreased methylation of UGT1A1 polyA tail CTD PMID:30157460 aflatoxin B1 increases expression ISO RGD:1350018 6480464 Aflatoxin B1 results in increased expression of UGT1A1 mRNA CTD PMID:29549414 , PMID:31542801 aflatoxin B1 multiple interactions EXP 6480464 Curcumin promotes the reaction [Aflatoxin B1 results in increased activity of UGT1A1 protein] CTD PMID:20015472 alizarin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of alizarin CTD PMID:14557274 all-trans-retinol multiple interactions EXP 6480464 Vitamin A inhibits the reaction [Triiodothyronine results in decreased expression of UGT1A1 mRNA] CTD PMID:11299074 alpha-tocotrienol increases expression ISO RGD:1350018 6480464 tocotrienol, alpha results in increased expression of UGT1A1 CTD PMID:15269186 amentoflavone decreases activity ISO RGD:1350018 6480464 amentoflavone results in decreased activity of UGT1A1 protein CTD PMID:29470958 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of UGT1A1 mRNA CTD PMID:18355885 , PMID:19483382 amitriptyline affects expression EXP 6480464 Amitriptyline affects the expression of UGT1A1 mRNA CTD PMID:18355885 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of UGT1A1 mRNA CTD PMID:16483693 androsterone multiple interactions ISO RGD:1350018 6480464 Androsterone inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 Anetholtrithion increases activity EXP 6480464 Anethole Trithione results in increased activity of UGT1A1 protein CTD PMID:8339252 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1350018 6480464 pyrazolanthrone inhibits the reaction [chrysin results in increased expression of UGT1A1 mRNA] CTD PMID:17256720 anthraflavic acid increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 2, 6-dihydroxyanthraquinone CTD PMID:12756209 , PMID:14557274 anthrarobin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of anthrarobin CTD PMID:14557274 apigenin increases expression ISO RGD:1350018 6480464 Apigenin results in increased expression of UGT1A1 mRNA CTD PMID:15090468 more ... apigenin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Apigenin CTD PMID:14557274 apigenin multiple interactions ISO RGD:1350018 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Apigenin results in increased expression of UGT1A1 mRNA], [sulforaphane co-treated with Apigenin] results in increased expression of UGT1A1 mRNA CTD PMID:15090468 arachidonic acid increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of UGT1A1 mRNA CTD PMID:23912714 Aroclor 1254 increases expression ISO RGD:1350018 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of UGT1A1 mRNA CTD PMID:16934159 , PMID:17851650 arsane increases expression ISO RGD:1350018 6480464 Arsenic results in increased expression of UGT1A1 mRNA CTD PMID:27060662 arsenic atom increases expression ISO RGD:1350018 6480464 Arsenic results in increased expression of UGT1A1 mRNA CTD PMID:27060662 atrazine multiple interactions ISO RGD:1350018 6480464 [Endosulfan co-treated with Atrazine] results in increased expression of UGT1A1 mRNA, [Endosulfan co-treated with Chlorpyrifos co-treated with Atrazine] results in increased expression of UGT1A1 mRNA CTD PMID:24343343 belinostat multiple interactions ISO RGD:1350018 6480464 belinostat inhibits the reaction [[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide], belinostat inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 belinostat increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of belinostat CTD PMID:23382909 belinostat decreases glucuronidation ISO RGD:1350018 6480464 UGT1A1 gene polymorphism results in decreased glucuronidation of belinostat CTD PMID:23382909 benzamidoxime multiple interactions ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of and results in decreased activity of benzamidoxime CTD PMID:15788365 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of UGT1A1 mRNA CTD PMID:19483382 benzo[a]pyrene multiple interactions ISO RGD:1350018 6480464 [Butyric Acid co-treated with Benzo(a)pyrene] results in increased expression of UGT1A1 mRNA more ... CTD PMID:12566446 more ... benzo[a]pyrene decreases expression ISO RGD:1350018 6480464 Benzo(a)pyrene results in decreased expression of UGT1A1 mRNA CTD PMID:32234424 benzo[a]pyrene increases expression ISO RGD:11476 6480464 Benzo(a)pyrene results in increased expression of UGT1A1 mRNA CTD PMID:20127859 , PMID:32417428 benzo[a]pyrene increases expression ISO RGD:1350018 6480464 Benzo(a)pyrene results in increased expression of UGT1A1 mRNA, Benzo(a)pyrene results in increased expression of UGT1A1 protein CTD PMID:20403331 more ... benzo[a]pyrene affects response to substance ISO RGD:1350018 6480464 UGT1A1 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:21507987 benzo[a]pyrene increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Benzo(a)pyrene CTD PMID:14557274 benzo[a]pyrene increases activity ISO RGD:1350018 6480464 Benzo(a)pyrene results in increased activity of UGT1A1 protein CTD PMID:17065433 bergomottin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of bergamottin analog CTD PMID:14557274 beta-naphthoflavone multiple interactions ISO RGD:1350018 6480464 beta-Naphthoflavone promotes the reaction [[AHR protein binds to UGT1A1 enhancer] which results in increased expression of UGT1A1 mRNA], beta-Naphthoflavone results in increased expression of and results in increased activity of UGT1A1 protein CTD PMID:12566446 beta-naphthoflavone increases expression ISO RGD:11476 6480464 beta-Naphthoflavone results in increased expression of UGT1A1 mRNA CTD PMID:19144771 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of UGT1A1 mRNA CTD PMID:19695238 , PMID:20607812 beta-naphthoflavone increases expression ISO RGD:1350018 6480464 beta-Naphthoflavone results in increased expression of UGT1A1 mRNA, beta-Naphthoflavone results in increased expression of UGT1A1 protein CTD PMID:16399344 more ... beta-naphthoflavone increases activity ISO RGD:1350018 6480464 beta-Naphthoflavone results in increased activity of UGT1A1 protein CTD PMID:16399344 beta-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 beta-tocotrienol increases expression ISO RGD:1350018 6480464 tocotrienol, beta results in increased expression of UGT1A1 CTD PMID:15269186 bilirubin IXalpha increases expression ISO RGD:1350018 6480464 Bilirubin results in increased expression of UGT1A1 mRNA CTD PMID:15382119 bilirubin IXalpha multiple interactions EXP 6480464 5-methoxypsoralen promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] more ... CTD PMID:17599282 bilirubin IXalpha increases glucuronidation EXP 6480464 UGT1A1 protein results in increased glucuronidation of Bilirubin CTD PMID:12153725 more ... bilirubin IXalpha increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Bilirubin, UGT1A1 results in increased glucuronidation of Bilirubin CTD PMID:15988124 more ... bilirubin IXalpha increases metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein results in increased metabolism of Bilirubin CTD PMID:23401472 , PMID:27060662 bilirubin IXalpha decreases glucuronidation ISO RGD:1350018 6480464 UGT1A1 gene mutant form results in decreased glucuronidation of Bilirubin CTD PMID:17898154 bilirubin IXalpha multiple interactions ISO RGD:1350018 6480464 5-methoxypsoralen promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] more ... CTD PMID:10950852 more ... bilirubin IXalpha decreases activity ISO RGD:1350018 6480464 Bilirubin results in decreased activity of UGT1A1 protein CTD PMID:15334623 biochanin A increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of biochanin A CTD PMID:14557274 biochanin A increases expression ISO RGD:1350018 6480464 biochanin A results in increased expression of UGT1A1 mRNA CTD PMID:31621310 biochanin A increases expression ISO RGD:11476 6480464 biochanin A results in increased expression of UGT1A1 mRNA CTD PMID:31621310 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:11476 6480464 [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2 more ... CTD PMID:23756648 bis(2-ethylhexyl) phthalate increases expression ISO RGD:11476 6480464 Diethylhexyl Phthalate results in increased expression of UGT1A1 mRNA CTD PMID:19144771 bisphenol A increases expression ISO RGD:1350018 6480464 bisphenol A results in increased expression of UGT1A1, bisphenol A results in increased expression of UGT1A1 mRNA CTD PMID:22214767 , PMID:31207516 bisphenol A decreases expression ISO RGD:11476 6480464 bisphenol A results in decreased expression of UGT1A1 mRNA CTD PMID:33221593 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of UGT1A1 mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO RGD:11476 6480464 [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of UGT1A1 mRNA more ... CTD PMID:23756648 , PMID:28123100 bisphenol A increases expression ISO RGD:11476 6480464 bisphenol A results in increased expression of UGT1A1 mRNA CTD PMID:21932408 bisphenol A increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of bisphenol A CTD PMID:18990428 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of UGT1A1 mRNA CTD PMID:26496021 bisphenol A decreases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein polymorphism results in decreased glucuronidation of bisphenol A CTD PMID:26999266 bisphenol A affects glucuronidation ISO RGD:1350018 6480464 UGT1A1 polymorphism affects the glucuronidation of bisphenol A CTD PMID:22154984 Bisphenol B increases expression ISO RGD:1350018 6480464 bisphenol B results in increased expression of UGT1A1 mRNA CTD PMID:22214767 bisphenol F increases expression ISO RGD:1350018 6480464 bisphenol F results in increased expression of UGT1A1 CTD PMID:31207516 Boldine increases expression EXP 6480464 boldine results in increased expression of UGT1A1 mRNA CTD PMID:25771127 Bropirimine increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of bropirimine CTD PMID:14555337 buprenorphine increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Buprenorphine CTD PMID:12756209 buta-1,3-diene increases expression ISO RGD:11476 6480464 1, 3-butadiene results in increased expression of UGT1A1 mRNA CTD PMID:29038090 butylated hydroxyanisole increases expression ISO RGD:1350018 6480464 Butylated Hydroxyanisole results in increased expression of UGT1A1 mRNA CTD PMID:18227147 butylated hydroxyanisole increases expression ISO RGD:11476 6480464 Butylated Hydroxyanisole results in increased expression of UGT1A1 mRNA CTD PMID:19144771 butyric acid multiple interactions ISO RGD:1350018 6480464 [Butyric Acid co-treated with Benzo(a)pyrene] results in increased expression of UGT1A1 mRNA more ... CTD PMID:30439556 , PMID:31621310 butyric acid increases expression ISO RGD:1350018 6480464 Butyric Acid results in increased expression of UGT1A1 mRNA CTD PMID:30439556 C.I. Natural Red 20 multiple interactions EXP 6480464 shikonin inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Estradiol] CTD PMID:31128210 C.I. Natural Red 20 multiple interactions ISO RGD:1350018 6480464 shikonin inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Estradiol] CTD PMID:31128210 cadmium dichloride increases expression ISO RGD:1350018 6480464 Cadmium Chloride analog results in increased expression of UGT1A1 mRNA CTD PMID:27060662 cadmium dichloride decreases expression ISO RGD:11476 6480464 Cadmium Chloride results in decreased expression of UGT1A1 mRNA CTD PMID:11958953 caffeine increases expression ISO RGD:1350018 6480464 Caffeine results in increased expression of UGT1A1 mRNA CTD PMID:18227147 calcitriol increases expression ISO RGD:1350018 6480464 Calcitriol results in increased expression of UGT1A1 mRNA CTD PMID:21592394 , PMID:27107558 calcitriol multiple interactions ISO RGD:1350018 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of UGT1A1 mRNA CTD PMID:21592394 calycosin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 7, 3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 cannabidiol increases expression ISO RGD:11476 6480464 Cannabidiol results in increased expression of UGT1A1 mRNA CTD PMID:31052254 capsaicin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 carbamazepine increases expression ISO RGD:1350018 6480464 Carbamazepine results in increased expression of UGT1A1 mRNA CTD PMID:27413119 carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of UGT1A1 mRNA CTD PMID:17381134 carbamazepine increases activity ISO RGD:1350018 6480464 Carbamazepine results in increased activity of UGT1A1 protein CTD PMID:27413119 carvedilol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of carvedilol CTD PMID:14744946 carvedilol affects metabolic processing ISO RGD:1350018 6480464 UGT1A1 gene polymorphism affects the metabolism of carvedilol CTD PMID:16849011 carvedilol affects glucuronidation ISO RGD:1350018 6480464 UGT1A1 gene polymorphism affects the glucuronidation of carvedilol CTD PMID:16849011 CGP 52608 multiple interactions ISO RGD:1350018 6480464 CGP 52608 promotes the reaction [RORA protein binds to UGT1A1 gene] CTD PMID:28238834 chalcones increases expression EXP 6480464 Chalcones analog results in increased expression of UGT1A1 protein CTD PMID:23963778 chenodeoxycholic acid increases expression ISO RGD:1350018 6480464 Chenodeoxycholic Acid results in increased expression of UGT1A1 mRNA CTD PMID:27174168 chenodeoxycholic acid multiple interactions ISO RGD:1350018 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of UGT1A1 mRNA CTD PMID:33819548 chenodeoxycholic acid multiple interactions ISO RGD:11476 6480464 Chenodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA], Chenodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein] CTD PMID:32976922 chlorogenic acid decreases activity ISO RGD:1350018 6480464 Chlorogenic Acid results in decreased activity of UGT1A1 protein CTD PMID:35868516 chlorpyrifos multiple interactions ISO RGD:1350018 6480464 [Endosulfan co-treated with Chlorpyrifos co-treated with Atrazine] results in increased expression of UGT1A1 mRNA, [Endosulfan co-treated with Chlorpyrifos] results in increased expression of UGT1A1 mRNA CTD PMID:24343343 chrysen-6-ol multiple interactions EXP 6480464 [Methylcholanthrene results in increased expression of UGT1A1 protein] which results in increased glucuronidation of 6-hydroxychrysene CTD PMID:1435739 chrysen-6-ol increases glucuronidation EXP 6480464 UGT1A1 protein results in increased glucuronidation of 6-hydroxychrysene CTD PMID:1435739 chrysin multiple interactions ISO RGD:1350018 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [chrysin results in increased expression of UGT1A1 mRNA] more ... CTD PMID:10950852 more ... chrysin multiple interactions EXP 6480464 chrysin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] CTD PMID:17599282 chrysin affects glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein affects the glucuronidation of chrysin CTD PMID:10950852 chrysin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of chrysin CTD PMID:14557274 chrysin increases expression ISO RGD:1350018 6480464 chrysin results in increased expression of UGT1A1 more ... CTD PMID:10950852 more ... ciprofibrate increases expression ISO RGD:11476 6480464 ciprofibrate results in increased expression of UGT1A1 mRNA CTD PMID:19144771 cis-caffeic acid decreases activity ISO RGD:1350018 6480464 caffeic acid results in decreased activity of UGT1A1 protein CTD PMID:35868516 cisplatin affects response to substance ISO RGD:1350018 6480464 UGT1A1 protein affects the susceptibility to Cisplatin CTD PMID:16217747 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of UGT1A1 mRNA, Cisplatin results in increased expression of UGT1A1 protein CTD PMID:18289764 , PMID:22023808 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of UGT1A1 mRNA, Clofibrate results in increased expression of UGT1A1 protein CTD PMID:12851107 more ... clofibrate affects expression EXP 6480464 Clofibrate affects the expression of UGT1A1 mRNA CTD PMID:19483382 clofibric acid increases expression ISO RGD:1350018 6480464 Clofibric Acid results in increased expression of UGT1A1 mRNA CTD PMID:15771232 Clofop increases expression ISO RGD:1350018 6480464 fenofibric acid results in increased expression of UGT1A1 mRNA CTD PMID:15771232 clomipramine affects expression EXP 6480464 Clomipramine affects the expression of UGT1A1 mRNA CTD PMID:18355885 clotrimazole affects expression ISO RGD:1350018 6480464 Clotrimazole affects the expression of UGT1A1 mRNA CTD PMID:15849716 clozapine increases expression ISO RGD:1350018 6480464 Clozapine results in increased expression of UGT1A1 mRNA CTD PMID:18227147 coumarins multiple interactions EXP 6480464 Coumarins analog promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] CTD PMID:17599282 coumarins multiple interactions ISO RGD:1350018 6480464 Coumarins analog promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] CTD PMID:17599282 coumestrol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Coumestrol CTD PMID:14557274 curcumin increases expression ISO RGD:1350018 6480464 Curcumin results in increased expression of UGT1A1 mRNA CTD PMID:16819192 curcumin multiple interactions EXP 6480464 Curcumin promotes the reaction [Aflatoxin B1 results in increased activity of UGT1A1 protein] CTD PMID:20015472 curcumin increases expression ISO RGD:11476 6480464 Curcumin analog results in increased expression of UGT1A1 mRNA, Curcumin analog results in increased expression of UGT1A1 protein CTD PMID:26991801 , PMID:29228771 curcumin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Curcumin CTD PMID:14557274 cycloheximide multiple interactions ISO RGD:1350018 6480464 [Cycloheximide co-treated with Estradiol] results in decreased expression of UGT1A1 mRNA CTD PMID:15072547 cycloheximide decreases expression ISO RGD:1350018 6480464 Cycloheximide results in decreased expression of UGT1A1 mRNA CTD PMID:15072547 cyclosporin A decreases expression ISO RGD:1350018 6480464 Cyclosporine results in decreased expression of UGT1A1 mRNA CTD PMID:32253466 cylindrospermopsin increases expression ISO RGD:1350018 6480464 cylindrospermopsin results in increased expression of UGT1A1 mRNA CTD PMID:23726867 cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of UGT1A1 mRNA CTD PMID:29038839 cyproconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of UGT1A1 mRNA, [cyproconazole co-treated with epoxiconazole] results in increased expression of UGT1A1 mRNA CTD PMID:29038839 daidzein increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of daidzein CTD PMID:14557274 daidzein increases activity ISO RGD:1350018 6480464 daidzein results in increased activity of UGT1A1 protein CTD PMID:16051636 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of UGT1A1 protein CTD PMID:32679240 delta-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 delta-tocotrienol increases expression ISO RGD:1350018 6480464 tocotrienol, delta results in increased expression of UGT1A1 CTD PMID:15269186 deoxycholic acid multiple interactions ISO RGD:1350018 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of UGT1A1 mRNA CTD PMID:33819548 dexamethasone increases expression ISO RGD:1350018 6480464 Dexamethasone results in increased expression of UGT1A1 mRNA, Dexamethasone results in increased expression of UGT1A1 protein CTD PMID:15557560 , PMID:15560369 dexamethasone increases expression ISO RGD:11476 6480464 Dexamethasone results in increased expression of UGT1A1 mRNA CTD PMID:21041162 , PMID:29222744 dexamethasone multiple interactions ISO RGD:11476 6480464 [Dexamethasone co-treated with Ibuprofen] results in increased expression of UGT1A1 mRNA more ... CTD PMID:16155002 , PMID:29222744 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of UGT1A1 mRNA CTD PMID:15102944 , PMID:20607812 dexamethasone decreases expression ISO RGD:11476 6480464 Dexamethasone results in decreased expression of UGT1A1 mRNA CTD PMID:19144771 diallyl disulfide increases activity EXP 6480464 diallyl disulfide results in increased activity of UGT1A1 protein CTD PMID:8339252 Diallyl sulfide increases expression EXP 6480464 allyl sulfide results in increased expression of UGT1A1 mRNA CTD PMID:19695238 diallyl trisulfide increases expression EXP 6480464 diallyl trisulfide results in increased expression of UGT1A1 mRNA CTD PMID:20650352 dibenzo[a,l]pyrene increases glycosylation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glycosylation of dibenzo(a, l)pyrene CTD PMID:21780761 diclofenac increases expression ISO RGD:1350018 6480464 Diclofenac results in increased expression of UGT1A1 mRNA CTD PMID:18227147 diclofenac multiple interactions ISO RGD:1350018 6480464 Diclofenac inhibits the reaction [[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide], Diclofenac inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 diclofenac decreases expression EXP 6480464 Diclofenac results in decreased expression of UGT1A1 mRNA CTD PMID:19022234 diclofenac decreases activity ISO RGD:1350018 6480464 Diclofenac results in decreased activity of UGT1A1 protein CTD PMID:15334623 , PMID:15593333 diethylstilbestrol multiple interactions ISO RGD:1350018 6480464 Androsterone inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Diethylstilbestrol], Phenylbutazone inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 diethylstilbestrol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Diethylstilbestrol CTD PMID:23126256 diflunisal decreases activity ISO RGD:1350018 6480464 Diflunisal results in decreased activity of UGT1A1 protein CTD PMID:15593333 dioxygen decreases expression ISO RGD:1350018 6480464 Oxygen deficiency results in decreased expression of UGT1A1 mRNA CTD PMID:19695866 dioxygen multiple interactions ISO RGD:1350018 6480464 [Acetaminophen co-treated with Oxygen deficiency] results in decreased expression of UGT1A1 mRNA more ... CTD PMID:33811995 dioxygen increases expression ISO RGD:1350018 6480464 Oxygen deficiency results in increased expression of UGT1A1 mRNA CTD PMID:33811995 dipyridamole multiple interactions ISO RGD:1350018 6480464 Dipyridamole inhibits the reaction [UGT1A1 protein results in increased glucuronidation of anhydroicaritin] CTD PMID:30237061 doxorubicin increases expression EXP 6480464 [Doxorubicin results in increased expression of NFE2L2 protein] which results in increased expression of UGT1A1 mRNA CTD PMID:24211725 doxorubicin multiple interactions EXP 6480464 [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in decreased expression of UGT1A1 mRNA] CTD PMID:26335259 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of UGT1A1 mRNA CTD PMID:26335259 emodin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Emodin CTD PMID:14557274 endosulfan increases expression ISO RGD:1350018 6480464 Endosulfan results in increased expression of UGT1A1 mRNA CTD PMID:24343343 endosulfan multiple interactions ISO RGD:1350018 6480464 [Endosulfan co-treated with Atrazine] results in increased expression of UGT1A1 mRNA more ... CTD PMID:24343343 entacapone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of entacapone CTD PMID:15802387 epoxiconazole multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of UGT1A1 mRNA, [cyproconazole co-treated with epoxiconazole] results in increased expression of UGT1A1 mRNA CTD PMID:29038839 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of UGT1A1 mRNA CTD PMID:29038839 equol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Equol CTD PMID:14557274 Erucin increases expression ISO RGD:1350018 6480464 erucin results in increased expression of UGT1A1 mRNA CTD PMID:15896333 Erucin multiple interactions ISO RGD:1350018 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of UGT1A1 mRNA], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of UGT1A1 mRNA] CTD PMID:15896333 Estragole multiple interactions ISO RGD:11476 6480464 [flumequine co-treated with estragole] results in decreased expression of UGT1A1 mRNA CTD PMID:31029721 estriol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Estriol, UGT1A1 protein results in increased glucuronidation of Estriol analog CTD PMID:15117964 estrone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Estrone, UGT1A1 protein results in increased glucuronidation of Estrone analog CTD PMID:15117964 , PMID:15472229 ethoxyquin increases expression ISO RGD:11476 6480464 Ethoxyquin results in increased expression of UGT1A1 mRNA CTD PMID:19144771 ethoxyquin increases expression EXP 6480464 Ethoxyquin results in increased expression of UGT1A1 mRNA CTD PMID:19695238 etoposide affects response to substance ISO RGD:1350018 6480464 UGT1A1 gene polymorphism affects the susceptibility to Etoposide CTD PMID:12969965 etoposide increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Etoposide CTD PMID:17151191 eugenol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Eugenol CTD PMID:14557274 ezetimibe increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Ezetimibe CTD PMID:14977865 farnesol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Farnesol CTD PMID:15320866 felbamate increases expression EXP 6480464 felbamate results in increased expression of UGT1A1 mRNA CTD PMID:17381134 fenofibrate increases expression ISO RGD:1350018 6480464 Fenofibrate results in increased expression of UGT1A1 mRNA CTD PMID:25572481 fenthion increases expression ISO RGD:11476 6480464 Fenthion results in increased expression of UGT1A1 mRNA CTD PMID:34813904 fipronil increases expression EXP 6480464 fipronil results in increased expression of UGT1A1 mRNA CTD PMID:22447239 , PMID:23962444 fipronil increases expression ISO RGD:11476 6480464 fipronil results in increased expression of UGT1A1 mRNA CTD PMID:23962444 fipronil-sulfone increases expression EXP 6480464 fipronil sulfone results in increased expression of UGT1A1 mRNA CTD PMID:22447239 fisetin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of fisetin CTD PMID:14557274 flavanone increases expression ISO RGD:11476 6480464 flavanone analog results in increased expression of UGT1A1 mRNA CTD PMID:31621310 flavonoids increases expression ISO RGD:1350018 6480464 Flavonoids results in increased expression of UGT1A1 mRNA, Flavonoids results in increased expression of UGT1A1 protein CTD PMID:15104253 flumequine decreases expression ISO RGD:11476 6480464 flumequine results in decreased expression of UGT1A1 mRNA CTD PMID:23681119 , PMID:31029721 flumequine multiple interactions ISO RGD:11476 6480464 [flumequine co-treated with estragole] results in decreased expression of UGT1A1 mRNA CTD PMID:31029721 flunitrazepam decreases activity ISO RGD:1350018 6480464 Flunitrazepam results in decreased activity of UGT1A1 protein CTD PMID:15334623 flurbiprofen increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Flurbiprofen CTD PMID:15843492 formononetin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of formononetin CTD PMID:14557274 fulvestrant increases expression ISO RGD:1350018 6480464 fulvestrant results in increased expression of UGT1A1 mRNA CTD PMID:15072547 furan increases methylation EXP 6480464 furan results in increased methylation of UGT1A1 gene CTD PMID:22079235 furosemide increases expression ISO RGD:1350018 6480464 Furosemide results in increased expression of UGT1A1 mRNA CTD PMID:18227147 fusidic acid multiple interactions ISO RGD:1350018 6480464 Fusidic Acid inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Estradiol] CTD PMID:27676153 galangin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of galangin CTD PMID:14557274 gamma-hexachlorocyclohexane increases activity EXP 6480464 Hexachlorocyclohexane results in increased activity of UGT1A1 protein CTD PMID:16641539 gamma-tocopherol increases expression ISO RGD:11476 6480464 gamma-Tocopherol results in increased expression of UGT1A1 mRNA CTD PMID:19115203 gamma-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 gemfibrozil increases expression ISO RGD:1350018 6480464 Gemfibrozil results in increased expression of UGT1A1 mRNA CTD PMID:15771232 genistein decreases activity ISO RGD:1350018 6480464 Genistein results in decreased activity of UGT1A1 protein CTD PMID:16051636 genistein multiple interactions ISO RGD:11476 6480464 Genistein inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA] CTD PMID:23333575 genistein decreases expression ISO RGD:1350018 6480464 Genistein results in decreased expression of UGT1A1 mRNA, Genistein results in decreased expression of UGT1A1 protein CTD PMID:18634814 genistein increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Genistein CTD PMID:14557274 , PMID:15988124 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of UGT1A1 mRNA CTD PMID:20849911 , PMID:22061828 Ginkgolide A increases expression ISO RGD:1350018 6480464 ginkgolide A results in increased expression of UGT1A1 mRNA CTD PMID:19034627 ginkgolide B increases expression ISO RGD:1350018 6480464 ginkgolide B results in increased expression of UGT1A1 mRNA CTD PMID:19034627 ginsenoside Rg1 multiple interactions EXP 6480464 ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA], ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein] CTD PMID:32198087 glabridin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of glabridin CTD PMID:25765239 glycochenodeoxycholic acid multiple interactions ISO RGD:1350018 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of UGT1A1 mRNA CTD PMID:33819548 glycocholic acid multiple interactions ISO RGD:1350018 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of UGT1A1 mRNA CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO RGD:1350018 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of UGT1A1 mRNA CTD PMID:33819548 gold atom decreases expression ISO RGD:1350018 6480464 Gold analog results in decreased expression of UGT1A1 mRNA CTD PMID:36057382 gold(0) decreases expression ISO RGD:1350018 6480464 Gold analog results in decreased expression of UGT1A1 mRNA CTD PMID:36057382 Grepafloxacin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of grepafloxacin CTD PMID:15769885 griseofulvin affects expression ISO RGD:11476 6480464 Griseofulvin affects the expression of UGT1A1 mRNA CTD PMID:12735108 hyperforin increases expression ISO RGD:1350018 6480464 hyperforin results in increased expression of UGT1A1 mRNA CTD PMID:24259679 ibuprofen increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Ibuprofen CTD PMID:15843492 ibuprofen multiple interactions ISO RGD:11476 6480464 [Dexamethasone co-treated with Ibuprofen] results in increased expression of UGT1A1 mRNA CTD PMID:29222744 ibuprofen increases expression ISO RGD:11476 6480464 Ibuprofen results in increased expression of UGT1A1 mRNA CTD PMID:29222744 imipramine affects expression EXP 6480464 Imipramine affects the expression of UGT1A1 mRNA CTD PMID:18355885 imperatorin multiple interactions EXP 6480464 imperatorin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] CTD PMID:17599282 imperatorin multiple interactions ISO RGD:1350018 6480464 imperatorin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin] CTD PMID:17599282 indometacin decreases activity ISO RGD:1350018 6480464 Indomethacin results in decreased activity of UGT1A1 protein CTD PMID:15593333 indometacin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Indomethacin CTD PMID:15843492 indoxyl sulfate increases expression ISO RGD:1350018 6480464 Indican results in increased expression of UGT1A1 mRNA CTD PMID:20000589 inulin multiple interactions ISO RGD:11476 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of UGT1A1 mRNA CTD PMID:36331819 irinotecan affects response to substance ISO RGD:1350018 6480464 UGT1A1 gene polymorphism affects the susceptibility to Irinotecan more ... CTD PMID:15517893 more ... irinotecan affects glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein mutant form affects the glucuronidation of Irinotecan CTD PMID:35930428 irinotecan multiple interactions ISO RGD:11476 6480464 MYD88 protein affects the reaction [Irinotecan results in decreased expression of UGT1A1 mRNA] more ... CTD PMID:35728726 irinotecan decreases expression ISO RGD:11476 6480464 Irinotecan results in decreased expression of UGT1A1 mRNA CTD PMID:35728726 irinotecan decreases activity ISO RGD:11476 6480464 Irinotecan results in decreased activity of UGT1A1 protein CTD PMID:35728726 irinotecan increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Irinotecan CTD PMID:15655543 more ... irinotecan decreases glucuronidation ISO RGD:1350018 6480464 UGT1A1 gene mutant form results in decreased glucuronidation of Irinotecan, UGT1A1 protein polymorphism results in decreased glucuronidation of Irinotecan CTD PMID:12960109 , PMID:17898154 irinotecan affects metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein affects the metabolism of Irinotecan CTD PMID:15523087 irinotecan increases metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein results in increased metabolism of Irinotecan CTD PMID:23401472 irinotecan increases glucuronidation EXP 6480464 UGT1A1 protein results in increased glucuronidation of Irinotecan CTD PMID:15833930 irinotecan multiple interactions ISO RGD:1350018 6480464 [Ketoconazole results in decreased activity of UGT1A1 protein] which results in decreased metabolism of Irinotecan more ... CTD PMID:15517893 more ... isoflavones multiple interactions ISO RGD:1350018 6480464 AHR protein affects the reaction [Isoflavones analog results in increased expression of UGT1A1 mRNA] CTD PMID:31621310 isoflavones increases expression ISO RGD:1350018 6480464 Isoflavones analog results in increased expression of UGT1A1 mRNA CTD PMID:31621310 isoflavones increases expression ISO RGD:11476 6480464 Isoflavones analog results in increased expression of UGT1A1 mRNA CTD PMID:31621310 isoliquiritigenin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of isoliquiritigenin CTD PMID:14557274 kaempferol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of kaempferol CTD PMID:14557274 kaempferol decreases activity ISO RGD:1350018 6480464 kaempferol results in decreased activity of UGT1A1 protein CTD PMID:35063619 kaempferol multiple interactions ISO RGD:11476 6480464 kaempferol inhibits the reaction [propacetamol results in decreased expression of UGT1A1 protein] CTD PMID:29574133 ketoconazole decreases activity ISO RGD:1350018 6480464 Ketoconazole results in decreased activity of UGT1A1 protein CTD PMID:22447115 ketoconazole affects expression EXP 6480464 Ketoconazole affects the expression of UGT1A1 mRNA CTD PMID:18355885 ketoconazole decreases expression ISO RGD:1350018 6480464 Ketoconazole results in decreased expression of UGT1A1 mRNA CTD PMID:16608920 ketoconazole multiple interactions ISO RGD:1350018 6480464 [Ketoconazole results in decreased activity of UGT1A1 protein] which results in decreased metabolism of irinotecan CTD PMID:22447115 ketoprofen decreases activity ISO RGD:1350018 6480464 Ketoprofen results in decreased activity of UGT1A1 protein CTD PMID:15593333 ketoprofen increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Ketoprofen CTD PMID:15843492 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of UGT1A1 mRNA CTD PMID:19483382 labetalol multiple interactions ISO RGD:1350018 6480464 [Uridine Diphosphate Glucuronic Acid co-treated with UGT1A1 protein] results in increased glucuronidation of Labetalol CTD PMID:18098064 lansoprazole increases expression EXP 6480464 Lansoprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 leflunomide increases expression ISO RGD:1350018 6480464 leflunomide results in increased expression of UGT1A1 mRNA CTD PMID:28988120 Licochalcone A multiple interactions ISO RGD:1350018 6480464 licochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT1A1 protein] CTD PMID:26875642 lithocholic acid multiple interactions ISO RGD:11476 6480464 1 more ... CTD PMID:19196849 lithocholic acid decreases expression ISO RGD:11476 6480464 Lithocholic Acid results in decreased expression of UGT1A1 mRNA CTD PMID:19196849 luteolin multiple interactions ISO RGD:1350018 6480464 Luteolin inhibits the reaction [Benzo(a)pyrene results in increased expression of UGT1A1 mRNA] CTD PMID:20403331 luteolin increases expression ISO RGD:1350018 6480464 Luteolin results in increased expression of UGT1A1 mRNA CTD PMID:29584932 LY294002 multiple interactions ISO RGD:1350018 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of UGT1A1 mRNA] CTD PMID:15896333 mangiferin increases expression ISO RGD:1350018 6480464 mangiferin results in increased expression of UGT1A1 mRNA CTD PMID:22815239 mangiferin decreases activity ISO RGD:1350018 6480464 mangiferin results in decreased activity of UGT1A1 protein CTD PMID:22815239 masoprocol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Masoprocol CTD PMID:14557274 Meclizine multiple interactions ISO RGD:11476 6480464 [Meclizine binds to and results in increased activity of NR1I3 protein] which results in increased expression of UGT1A1 mRNA CTD PMID:15272053 MeIQx increases expression ISO RGD:1350018 6480464 2-amino-3 more ... CTD PMID:22138251 , PMID:23810796 metazachlor increases expression EXP 6480464 metazachlor results in increased expression of UGT1A1 mRNA CTD PMID:31465819 methidathion increases expression ISO RGD:11476 6480464 methidathion results in increased expression of UGT1A1 mRNA CTD PMID:34813904 methotrexate increases expression ISO RGD:1350018 6480464 Methotrexate results in increased expression of UGT1A1 mRNA CTD PMID:20854796 methoxychlor increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Methoxychlor metabolite CTD PMID:15205390 MK 571 multiple interactions ISO RGD:1350018 6480464 verlukast inhibits the reaction [UGT1A1 protein results in increased glucuronidation of anhydroicaritin] CTD PMID:30237061 morin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of morin CTD PMID:14557274 morin decreases activity ISO RGD:1350018 6480464 morin results in decreased activity of UGT1A1 protein CTD PMID:35063619 morin multiple interactions ISO RGD:1350018 6480464 AHR gene mutant form inhibits the reaction [morin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 morphine increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Morphine CTD PMID:12920162 moxifloxacin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of moxifloxacin CTD PMID:15769885 Muraglitazar increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of muraglitazar CTD PMID:17898154 myricetin decreases activity ISO RGD:1350018 6480464 myricetin results in decreased activity of UGT1A1 protein CTD PMID:35063619 N-butyl-N-(4-hydroxybutyl)nitrosamine decreases expression ISO RGD:11476 6480464 Butylhydroxybutylnitrosamine results in decreased expression of UGT1A7 mRNA CTD PMID:15374950 N-butyl-N-(4-hydroxybutyl)nitrosamine multiple interactions ISO RGD:11476 6480464 oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A7 mRNA] CTD PMID:15374950 N-hydroxy-PhIP multiple interactions ISO RGD:1350018 6480464 UGT1A1 promoter polymorphism affects the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:15769885 , PMID:15986396 N-hydroxy-PhIP affects metabolic processing ISO RGD:1350018 6480464 UGT1A1 promoter polymorphism affects the metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4, 5-b)pyridine CTD PMID:15986396 N-hydroxy-PhIP increases metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4, 5-b)pyridine CTD PMID:15986396 N-hydroxy-PhIP increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4, 5-b)pyridine CTD PMID:11442279 , PMID:15310245 N-nitrosodiethylamine multiple interactions EXP 6480464 [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of UGT1A1 mRNA CTD PMID:18977376 naproxen decreases activity ISO RGD:1350018 6480464 Naproxen results in decreased activity of UGT1A1 protein CTD PMID:15593333 naproxen increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Naproxen CTD PMID:15843492 Niflumic acid decreases activity ISO RGD:1350018 6480464 Niflumic Acid results in decreased activity of UGT1A1 protein CTD PMID:15593333 nilotinib decreases activity ISO RGD:1350018 6480464 nilotinib results in decreased activity of UGT1A1 protein CTD PMID:26875642 Nor-9-carboxy-delta9-THC multiple interactions ISO RGD:1350018 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of UGT1A1 gene CTD PMID:30521419 notoginsenoside R1 multiple interactions ISO RGD:1350018 6480464 NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of UGT1A1 mRNA] CTD PMID:25472953 notoginsenoside R1 increases expression ISO RGD:11476 6480464 notoginsenoside R1 results in increased expression of UGT1A1 mRNA CTD PMID:25472953 notoginsenoside R1 increases expression ISO RGD:1350018 6480464 notoginsenoside R1 results in increased expression of UGT1A1 mRNA CTD PMID:25472953 obeticholic acid increases expression ISO RGD:1350018 6480464 obeticholic acid results in increased expression of UGT1A1 mRNA CTD PMID:27939613 obeticholic acid increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of obeticholic acid CTD PMID:31299240 ofloxacin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Ofloxacin CTD PMID:15769885 oltipraz increases expression ISO RGD:11476 6480464 oltipraz results in increased expression of UGT1A1 mRNA CTD PMID:19144771 oltipraz multiple interactions ISO RGD:11476 6480464 oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A7 mRNA] CTD PMID:15374950 omeprazole increases expression ISO RGD:1350018 6480464 Omeprazole results in increased expression of UGT1A1 mRNA CTD PMID:19118567 omeprazole increases expression EXP 6480464 Omeprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of UGT1A1 mRNA CTD PMID:19483382 opicapone decreases activity ISO RGD:1350018 6480464 opicapone results in decreased activity of UGT1A1 protein CTD PMID:35810997 ortho-Aminoazotoluene multiple interactions ISO RGD:11476 6480464 NR1I3 gene mutant form inhibits the reaction [o-Aminoazotoluene results in increased expression of UGT1A1 mRNA] CTD PMID:21672546 ortho-Aminoazotoluene increases expression ISO RGD:11476 6480464 o-Aminoazotoluene results in increased expression of UGT1A1 mRNA CTD PMID:21672546 osimertinib multiple interactions ISO RGD:1350018 6480464 osimertinib inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Hymecromone] CTD PMID:34044055 osimertinib decreases activity ISO RGD:1350018 6480464 osimertinib results in decreased activity of UGT1A1 protein CTD PMID:34044055 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of UGT1A1 mRNA CTD PMID:23439660 paclitaxel multiple interactions ISO RGD:11476 6480464 TLR4 protein mutant form inhibits the reaction [Paclitaxel results in increased expression of UGT1A1 mRNA], TLR4 protein mutant form inhibits the reaction [Paclitaxel results in increased expression of UGT1A1 protein] CTD PMID:28242239 paclitaxel increases expression ISO RGD:11476 6480464 Paclitaxel results in increased expression of UGT1A1 mRNA, Paclitaxel results in increased expression of UGT1A1 protein CTD PMID:28242239 pantoprazole increases expression EXP 6480464 pantoprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 paracetamol decreases expression ISO RGD:11476 6480464 Acetaminophen results in decreased expression of UGT1A1 mRNA CTD PMID:23333575 , PMID:26772156 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of UGT1A1 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:1350018 6480464 Acetaminophen results in increased expression of UGT1A1 mRNA CTD PMID:33811995 paracetamol multiple interactions ISO RGD:1350018 6480464 [Acetaminophen co-treated with Oxygen deficiency] results in decreased expression of UGT1A1 mRNA, Oxygen deficiency inhibits the reaction [Acetaminophen results in increased expression of UGT1A1 mRNA] CTD PMID:33811995 paracetamol decreases expression ISO RGD:1350018 6480464 Acetaminophen results in decreased expression of UGT1A1 mRNA CTD PMID:29067470 paracetamol increases response to substance EXP 6480464 UGT1A1 gene mutant form results in increased susceptibility to Acetaminophen CTD PMID:6776978 paracetamol affects expression ISO RGD:11476 6480464 Acetaminophen affects the expression of UGT1A1 mRNA CTD PMID:17562736 paracetamol decreases activity ISO RGD:1350018 6480464 Acetaminophen results in decreased activity of UGT1A1 protein CTD PMID:15593333 paracetamol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Acetaminophen CTD PMID:17898154 paracetamol multiple interactions ISO RGD:11476 6480464 Genistein inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA], hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA] CTD PMID:23333575 , PMID:26772156 parathion increases expression ISO RGD:1350018 6480464 Parathion results in increased expression of UGT1A1 mRNA CTD PMID:17982697 parathion increases expression ISO RGD:11476 6480464 Parathion results in increased expression of UGT1A1 mRNA CTD PMID:34813904 perfluorobutyric acid increases expression EXP 6480464 perfluorobutyric acid analog results in increased expression of UGT1A1 mRNA CTD PMID:21878386 perfluorodecanoic acid increases expression ISO RGD:11476 6480464 perfluorodecanoic acid results in increased expression of UGT1A1 mRNA CTD PMID:27344344 perfluorodecanoic acid increases expression ISO RGD:1350018 6480464 perfluorodecanoic acid results in increased expression of UGT1A1 mRNA CTD PMID:35337807 perfluorodecanoic acid multiple interactions ISO RGD:11476 6480464 PPARA protein affects the reaction [perfluorodecanoic acid results in increased expression of UGT1A1 mRNA] CTD PMID:27344344 perfluorododecanoic acid decreases expression ISO RGD:1350018 6480464 perfluorododecanoic acid results in decreased expression of UGT1A1 mRNA CTD PMID:35337807 perfluorohexanesulfonic acid increases expression ISO RGD:1350018 6480464 perfluorohexanesulfonic acid results in increased expression of UGT1A1 mRNA CTD PMID:35337807 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of UGT1A1 mRNA CTD PMID:19045937 perfluorooctane-1-sulfonic acid increases expression ISO RGD:11476 6480464 perfluorooctane sulfonic acid results in increased expression of UGT1A1 mRNA CTD PMID:32979393 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:11476 6480464 [Dietary Fats co-treated with perfluorooctane sulfonic acid] results in increased expression of UGT1A1 mRNA more ... CTD PMID:32979393 , PMID:36331819 perfluorooctane-1-sulfonic acid increases expression ISO RGD:1350018 6480464 perfluorooctane sulfonic acid results in increased expression of UGT1A1 mRNA CTD PMID:32253466 , PMID:35337807 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1350018 6480464 perfluorooctane sulfonic acid results in decreased expression of UGT1A1 mRNA CTD PMID:31809754 perfluorooctanoic acid decreases expression ISO RGD:1350018 6480464 perfluorooctanoic acid results in decreased expression of UGT1A1 mRNA CTD PMID:31809754 perfluorooctanoic acid increases expression ISO RGD:1350018 6480464 perfluorooctanoic acid results in increased expression of UGT1A1 mRNA CTD PMID:32253466 , PMID:35337807 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of UGT1A1 protein CTD PMID:34958885 phenacetin increases response to substance EXP 6480464 UGT1A1 gene mutant form results in increased susceptibility to Phenacetin CTD PMID:6776978 phenanthrene multiple interactions ISO RGD:11476 6480464 NR1I3 gene mutant form inhibits the reaction [phenanthrene results in increased expression of UGT1A1 mRNA] CTD PMID:31181217 phenanthrene increases expression ISO RGD:11476 6480464 phenanthrene results in increased expression of UGT1A1 mRNA CTD PMID:31181217 phenobarbital increases expression ISO RGD:1350018 6480464 Phenobarbital results in increased expression of UGT1A1 mRNA CTD PMID:19084549 phenobarbital increases expression ISO RGD:11476 6480464 Phenobarbital results in increased expression of UGT1A1 mRNA, Phenobarbital results in increased expression of UGT1A1 protein CTD PMID:15986414 more ... phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of UGT1A1 mRNA, Phenobarbital results in increased expression of UGT1A1 protein CTD PMID:17381134 more ... phenobarbital multiple interactions EXP 6480464 Phenobarbital results in increased expression of and results in increased activity of UGT1A1 protein CTD PMID:20932986 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of UGT1A1 mRNA CTD PMID:24090815 phenobarbital multiple interactions ISO RGD:11476 6480464 NR1I3 protein promotes the reaction [Phenobarbital inhibits the reaction [Lithocholic Acid results in decreased expression of UGT1A1 mRNA]] more ... CTD PMID:19196849 , PMID:20932986 phenylbutazone multiple interactions ISO RGD:1350018 6480464 Phenylbutazone inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 phenytoin affects expression ISO RGD:1350018 6480464 Phenytoin affects the expression of UGT1A1 mRNA CTD PMID:15849716 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of UGT1A1 mRNA CTD PMID:17381134 phenytoin increases activity ISO RGD:11476 6480464 Phenytoin results in increased activity of UGT1A1 protein CTD PMID:27413119 phenytoin multiple interactions ISO RGD:1350018 6480464 Phenytoin results in increased expression of and results in increased activity of UGT1A1 protein CTD PMID:27413119 phenytoin increases expression ISO RGD:1350018 6480464 Phenytoin results in increased expression of UGT1A1 mRNA, Phenytoin results in increased expression of UGT1A1 protein CTD PMID:10421657 , PMID:27413119 PhIP multiple interactions ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of and results in decreased activity of 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:15708579 , PMID:22138251 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of UGT1A1 mRNA CTD PMID:29877212 PhIP increases expression ISO RGD:1350018 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of UGT1A1 mRNA CTD PMID:22138251 more ... phloretin decreases activity ISO RGD:1350018 6480464 Phloretin results in decreased activity of UGT1A1 protein CTD PMID:35868516 phlorizin decreases activity ISO RGD:1350018 6480464 Phlorhizin results in decreased activity of UGT1A1 protein CTD PMID:35868516 Picroside ii multiple interactions ISO RGD:11476 6480464 picroside II inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA], picroside II inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein] CTD PMID:32976922 pioglitazone increases expression ISO RGD:1350018 6480464 Pioglitazone results in increased expression of UGT1A1 mRNA CTD PMID:31233785 pirinixic acid increases expression ISO RGD:1350018 6480464 pirinixic acid results in increased expression of UGT1A1 mRNA, pirinixic acid results in increased expression of UGT1A1 protein CTD PMID:17151188 pirinixic acid increases expression ISO RGD:11476 6480464 pirinixic acid results in increased expression of UGT1A1 mRNA CTD PMID:17151188 , PMID:23811191 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of UGT1A1 mRNA CTD PMID:19483382 plumbagin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of plumbagin CTD PMID:14557274 pregnenolone 16alpha-carbonitrile increases activity ISO RGD:1350018 6480464 Pregnenolone Carbonitrile results in increased activity of UGT1A1 protein CTD PMID:16155002 , PMID:27413119 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:11476 6480464 Pregnenolone Carbonitrile results in increased expression of UGT1A1 mRNA, Pregnenolone Carbonitrile results in increased expression of UGT1A7 mRNA CTD PMID:19144771 more ... pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of UGT1A1 mRNA CTD PMID:19162173 , PMID:22659317 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:11476 6480464 [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of UGT1A1 mRNA more ... CTD PMID:16155002 , PMID:22496397 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1350018 6480464 Pregnenolone Carbonitrile results in increased expression of UGT1A1 mRNA, Pregnenolone Carbonitrile results in increased expression of UGT1A1 protein CTD PMID:16155002 , PMID:27413119 prochloraz multiple interactions EXP 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of UGT1A1 mRNA CTD PMID:29038839 progesterone multiple interactions ISO RGD:1350018 6480464 [Progesterone co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA CTD PMID:18098064 progesterone multiple interactions EXP 6480464 [Progesterone co-treated with Estradiol] affects the expression of UGT1A1 mRNA CTD PMID:24777823 propacetamol decreases expression ISO RGD:11476 6480464 propacetamol results in decreased expression of UGT1A1 protein CTD PMID:29574133 propacetamol multiple interactions ISO RGD:11476 6480464 kaempferol inhibits the reaction [propacetamol results in decreased expression of UGT1A1 protein] CTD PMID:29574133 propiconazole increases expression EXP 6480464 propiconazole results in increased expression of UGT1A1 mRNA CTD PMID:19409404 , PMID:19423681 prostaglandin B1 increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of prostaglandin B1 CTD PMID:15231852 prostaglandin E2 increases chemical synthesis EXP 6480464 UGT1A1 protein mutant form results in increased chemical synthesis of Dinoprostone CTD PMID:3864191 prostaglandin F2alpha increases chemical synthesis EXP 6480464 UGT1A1 protein mutant form results in increased chemical synthesis of Dinoprost CTD PMID:3864191 pterostilbene increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of pterostilbene CTD PMID:23965644 pterostilbene multiple interactions ISO RGD:1350018 6480464 pterostilbene inhibits the reaction [[UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 pterostilbene decreases activity ISO RGD:1350018 6480464 pterostilbene results in decreased activity of UGT1A1 protein CTD PMID:31812603 puerarin increases metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein results in increased metabolism of puerarin CTD PMID:22648071 pyrene multiple interactions ISO RGD:11476 6480464 [AHR affects the susceptibility to pyrene] which affects the expression of UGT1A1 mRNA CTD PMID:17618724 quercetin multiple interactions ISO RGD:1350018 6480464 AHR gene mutant form inhibits the reaction [Quercetin results in increased expression of UGT1A1 mRNA], chrysin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Quercetin] CTD PMID:11442279 , PMID:29584932 quercetin decreases activity ISO RGD:1350018 6480464 Quercetin results in decreased activity of UGT1A1 protein CTD PMID:35063619 quercetin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Quercetin CTD PMID:11442279 , PMID:14557274 quercetin increases expression EXP 6480464 Quercetin results in increased expression of UGT1A1 mRNA CTD PMID:21565894 quercetin increases expression ISO RGD:1350018 6480464 Quercetin results in increased expression of UGT1A1 mRNA CTD PMID:12756216 , PMID:29584932 quercetin 3-O-beta-D-galactopyranoside multiple interactions ISO RGD:11476 6480464 hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA] CTD PMID:26772156 quercetin 3-O-beta-D-galactopyranoside increases expression ISO RGD:11476 6480464 hyperoside results in increased expression of UGT1A1 mRNA CTD PMID:26772156 quinizarin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of 1, 4-dihydroxyanthraquinone CTD PMID:14557274 rabeprazole increases expression EXP 6480464 Rabeprazole results in increased expression of UGT1A1 mRNA CTD PMID:25626140 resveratrol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of resveratrol CTD PMID:17991766 , PMID:23965644 resveratrol affects expression EXP 6480464 resveratrol affects the expression of UGT1A1 mRNA CTD PMID:15748624 resveratrol increases activity ISO RGD:1350018 6480464 resveratrol results in increased activity of UGT1A1 protein CTD PMID:20716633 resveratrol increases expression ISO RGD:1350018 6480464 resveratrol results in increased expression of UGT1A1 mRNA, resveratrol results in increased expression of UGT1A1 protein CTD PMID:17287390 retinyl acetate multiple interactions ISO RGD:11476 6480464 [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of UGT1A1 mRNA CTD PMID:28123100 rifampicin affects expression ISO RGD:1350018 6480464 Rifampin affects the expression of UGT1A1 mRNA CTD PMID:15849716 rifampicin increases expression ISO RGD:1350018 6480464 Rifampin results in increased expression of UGT1A1 mRNA CTD PMID:15104253 more ... rifampicin multiple interactions ISO RGD:1350018 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA, [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of UGT1A1 mRNA CTD PMID:18098064 , PMID:29162470 ritonavir affects expression ISO RGD:1350018 6480464 Ritonavir affects the expression of UGT1A1 mRNA CTD PMID:15849716 robinetin increases expression ISO RGD:1350018 6480464 robinetin results in increased expression of UGT1A1 mRNA CTD PMID:29584932 robinetin multiple interactions ISO RGD:1350018 6480464 AHR gene mutant form inhibits the reaction [robinetin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 SB 203580 multiple interactions ISO RGD:1350018 6480464 SB 203580 inhibits the reaction [chrysin results in increased expression of UGT1A1 mRNA] CTD PMID:17256720 scopoletin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Scopoletin CTD PMID:15802387 sevoflurane affects expression EXP 6480464 Sevoflurane affects the expression of UGT1A1 mRNA CTD PMID:15967596 Shikonin multiple interactions EXP 6480464 shikonin inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Estradiol] CTD PMID:31128210 Shikonin multiple interactions ISO RGD:1350018 6480464 shikonin inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Estradiol] CTD PMID:31128210 silibinin multiple interactions ISO RGD:1350018 6480464 Silybin inhibits the reaction [UGT1A1 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin] CTD PMID:15155549 silibinin decreases activity EXP 6480464 Silybin metabolite results in decreased activity of UGT1A1 protein CTD PMID:15921999 Sitafloxacin increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of sitafloxacin CTD PMID:15769885 sodium acetate trihydrate multiple interactions ISO RGD:1350018 6480464 Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA] CTD PMID:31621310 sodium acetate trihydrate multiple interactions ISO RGD:11476 6480464 Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA] CTD PMID:31621310 sodium arsenite decreases expression ISO RGD:11476 6480464 sodium arsenite results in decreased expression of UGT1A1 mRNA CTD PMID:17350061 sodium arsenite increases expression ISO RGD:11476 6480464 sodium arsenite results in increased expression of UGT1A1 protein CTD PMID:29044176 sodium propionate multiple interactions ISO RGD:1350018 6480464 sodium propionate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA] CTD PMID:31621310 spironolactone increases activity EXP 6480464 Spironolactone results in increased activity of UGT1A1 protein CTD PMID:12818378 spironolactone increases expression EXP 6480464 Spironolactone results in increased expression of UGT1A1 mRNA CTD PMID:12818378 spironolactone increases expression ISO RGD:11476 6480464 Spironolactone results in increased expression of UGT1A1 mRNA CTD PMID:19144771 sulforaphane multiple interactions ISO RGD:1350018 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of UGT1A1 mRNA], [sulforaphane co-treated with Apigenin] results in increased expression of UGT1A1 mRNA CTD PMID:15090468 sulforaphane increases expression ISO RGD:1350018 6480464 sulforaphane results in increased expression of UGT1A1 mRNA, sulforaphane results in increased expression of UGT1A1 protein CTD PMID:12151360 more ... sulforaphane decreases expression ISO RGD:1350018 6480464 sulforaphane results in decreased expression of UGT1A1 mRNA CTD PMID:12949046 sulindac increases activity ISO RGD:1350018 6480464 Sulindac results in increased activity of UGT1A1 protein CTD PMID:17985343 sulindac increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Sulindac CTD PMID:15843492 sulindac increases expression ISO RGD:1350018 6480464 Sulindac results in increased expression of UGT1A1 mRNA CTD PMID:17985343 sulindac sulfide increases activity ISO RGD:1350018 6480464 sulindac sulfide results in increased activity of UGT1A1 protein CTD PMID:17985343 sulindac sulfide increases expression ISO RGD:1350018 6480464 sulindac sulfide results in increased expression of UGT1A1 mRNA CTD PMID:17985343 sulindac sulfone increases activity ISO RGD:1350018 6480464 sulindac sulfone results in increased activity of UGT1A1 protein CTD PMID:17985343 sulindac sulfone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of sulindac sulfone CTD PMID:15843492 sulindac sulfone increases expression ISO RGD:1350018 6480464 sulindac sulfone results in increased expression of UGT1A1 mRNA CTD PMID:17985343 sunitinib increases expression EXP 6480464 sunitinib results in increased expression of UGT1A1 mRNA CTD PMID:26797788 tamoxifen multiple interactions ISO RGD:11476 6480464 [Carbon Tetrachloride co-treated with Tamoxifen] affects the expression of UGT1A1 mRNA CTD PMID:29974145 taurine multiple interactions EXP 6480464 [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in decreased expression of UGT1A1 mRNA], [Taurine binds to Zinc] which results in decreased expression of UGT1A1 mRNA CTD PMID:26335259 tebuconazole increases expression ISO RGD:1350018 6480464 tebuconazole results in increased expression of UGT1A1 mRNA CTD PMID:30458266 tert-butyl ethyl ether decreases expression EXP 6480464 ethyl tert-butyl ether results in decreased expression of UGT1A1 mRNA CTD PMID:24090815 testosterone multiple interactions ISO RGD:1350018 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of UGT1A1 mRNA CTD PMID:21592394 testosterone increases expression ISO RGD:1350018 6480464 Testosterone results in increased expression of UGT1A1 mRNA CTD PMID:21592394 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of UGT1A1 mRNA, Carbon Tetrachloride affects the expression of UGT1A1 protein CTD PMID:32380060 tetrachloromethane multiple interactions ISO RGD:11476 6480464 [Carbon Tetrachloride co-treated with Tamoxifen] affects the expression of UGT1A1 mRNA CTD PMID:29974145 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of UGT1A1 mRNA CTD PMID:19483382 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of UGT1A1 mRNA CTD PMID:26222700 thymol increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Thymol CTD PMID:14557274 thymol sulfate(1-) increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Thymol CTD PMID:14557274 thyroxine increases expression EXP 6480464 Thyroxine results in increased expression of UGT1A1 mRNA CTD PMID:17884940 ticlopidine increases expression ISO RGD:1350018 6480464 Ticlopidine results in increased expression of UGT1A1 mRNA CTD PMID:18227147 tienilic acid increases expression ISO RGD:1350018 6480464 Ticrynafen results in increased expression of UGT1A1 mRNA CTD PMID:18227147 trans-caffeic acid decreases activity ISO RGD:1350018 6480464 caffeic acid results in decreased activity of UGT1A1 protein CTD PMID:35868516 trans-piceid increases hydrolysis ISO RGD:1350018 6480464 UGT1A1 protein results in increased hydrolysis of polydatin metabolite CTD PMID:17009167 triadimefon increases expression EXP 6480464 triadimefon results in increased expression of UGT1A1 mRNA CTD PMID:19409404 , PMID:19423681 trichloroethene increases expression ISO RGD:11476 6480464 Trichloroethylene results in increased expression of UGT1A1 mRNA CTD PMID:19254012 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of UGT1A1 mRNA CTD PMID:33387578 trichostatin A increases expression ISO RGD:1350018 6480464 trichostatin A results in increased expression of UGT1A1 mRNA CTD PMID:30439556 trichostatin A multiple interactions ISO RGD:1350018 6480464 [trichostatin A co-treated with Benzo(a)pyrene] results in increased expression of UGT1A1 mRNA, trichostatin A promotes the reaction [Benzo(a)pyrene results in increased expression of UGT1A1 mRNA] CTD PMID:30439556 triclocarban multiple interactions ISO RGD:1350018 6480464 NR1I3 gene mutant form inhibits the reaction [triclocarban results in increased expression of UGT1A1 mRNA] CTD PMID:22761658 triclocarban increases expression ISO RGD:1350018 6480464 triclocarban results in increased expression of UGT1A1 mRNA CTD PMID:22761658 triclosan increases expression EXP 6480464 Triclosan results in increased expression of UGT1A1 mRNA CTD PMID:19910387 triclosan increases expression ISO RGD:1350018 6480464 Triclosan results in increased expression of UGT1A1 mRNA CTD PMID:29849464 trifluralin increases expression EXP 6480464 Trifluralin results in increased expression of UGT1A1 mRNA CTD PMID:18582544 troglitazone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of troglitazone CTD PMID:11201174 troglitazone increases expression ISO RGD:1350018 6480464 troglitazone results in increased expression of UGT1A1 mRNA CTD PMID:25572481 tunicamycin increases expression ISO RGD:11476 6480464 Tunicamycin results in increased expression of UGT1A1 mRNA CTD PMID:35341795 UDP-alpha-D-glucuronic acid multiple interactions ISO RGD:1350018 6480464 [Uridine Diphosphate Glucuronic Acid co-treated with UGT1A1 protein] results in increased glucuronidation of Labetalol CTD PMID:18098064 ursodeoxycholic acid increases expression ISO RGD:11476 6480464 Ursodeoxycholic Acid results in increased expression of UGT1A1 mRNA CTD PMID:18687751 ursodeoxycholic acid multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA], Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein] CTD PMID:32198087 valproic acid increases expression ISO RGD:1350018 6480464 Valproic Acid results in increased expression of UGT1A1 mRNA CTD PMID:25084468 valproic acid affects expression ISO RGD:1350018 6480464 Valproic Acid affects the expression of UGT1A1 mRNA CTD PMID:29501571 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of UGT1A1 mRNA CTD PMID:17381134 vorinostat affects response to substance ISO RGD:1350018 6480464 UGT1A1 gene polymorphism affects the susceptibility to vorinostat CTD PMID:20479100 warfarin affects response to substance ISO RGD:1350018 6480464 UGT1A1 gene SNP affects the susceptibility to Warfarin, UGT1A1 polymorphism affects the susceptibility to Warfarin CTD PMID:25312789 , PMID:26223945 warfarin multiple interactions ISO RGD:1350018 6480464 [UGT1A1 protein results in increased metabolism of Warfarin] which results in increased chemical synthesis of Glucuronides more ... CTD PMID:19408964 , PMID:25393417 warfarin increases metabolic processing ISO RGD:1350018 6480464 UGT1A1 protein results in increased metabolism of Warfarin CTD PMID:19408964 xanthohumol increases expression ISO RGD:1350018 6480464 xanthohumol results in increased expression of UGT1A1 mRNA CTD PMID:22138251 xanthohumol multiple interactions ISO RGD:1350018 6480464 xanthohumol promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of UGT1A1 mRNA] CTD PMID:22138251 zearalenone increases glucuronidation ISO RGD:1350018 6480464 UGT1A1 protein results in increased glucuronidation of Zearalenone CTD PMID:14557274 zinc atom multiple interactions EXP 6480464 [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in decreased expression of UGT1A1 mRNA], [Taurine binds to Zinc] which results in decreased expression of UGT1A1 mRNA CTD PMID:26335259 zinc(0) multiple interactions EXP 6480464 [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in decreased expression of UGT1A1 mRNA], [Taurine binds to Zinc] which results in decreased expression of UGT1A1 mRNA CTD PMID:26335259
