GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ugt1a1 | decreases glucuronidation | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | UGT1A1 gene polymorphism results in decreased glucuronidation of belinostat | PMID:23382909 | Ugt1a1 | increases glucuronidation | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | UGT1A1 protein results in increased glucuronidation of belinostat | PMID:23382909 | Ugt1a1 | multiple interactions | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | belinostat inhibits the reaction [[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; belinostat inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Hymecromone] | PMID:33290829 | | ||||||||||||||||||||||
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