Ugt1a1 (UDP glucuronosyltransferase 1 family, polypeptide A1) - Rat Genome Database
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Gene: Ugt1a1 (UDP glucuronosyltransferase 1 family, polypeptide A1) Mus musculus
Analyze
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase 1 family, polypeptide A1
RGD ID: 11476
MGI Page MGI
Description: Predicted to have several functions, including glucuronosyltransferase activity; protein dimerization activity; and retinoic acid binding activity. Predicted to be involved in several processes, including biphenyl catabolic process; cellular glucuronidation; and negative regulation of cellular glucuronidation. Localizes to endoplasmic reticulum chaperone complex and integral component of plasma membrane. Is expressed in alimentary system; nervous system; and urinary system. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; female reproductive organ cancer (multiple); and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1); PARTICIPATES IN axitinib pharmacokinetics pathway; codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; INTERACTS WITH (S)-naringenin; (Z)-ligustilide; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gnt; Gnt1; UDP-glucuronosyltransferase 1 family, member 1; UDP-glucuronosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1A1; UDPGT; UDPGT 1-1; Udpgt-; Udpgt-1a; UGT1*1; UGT1-01; UGT1.1; UGT1A0; UGT1A01; UgtBr; UgtBr1
RGD Orthologs
Human
Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Ugt1a1-rs1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39188,139,681 - 88,147,724 (+)NCBIGRCm39mm39
GRCm38188,211,959 - 88,220,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl188,211,959 - 88,218,997 (+)EnsemblGRCm38mm10GRCm38
MGSCv37190,108,534 - 90,116,577 (+)NCBIGRCm37mm9NCBIm37
MGSCv36190,043,130 - 90,050,148 (+)NCBImm8
Celera191,173,026 - 91,181,062 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(+)-taxifolin  (ISO)
(5Z,8Z,11Z,13E)-15-HETE  (ISO)
(S)-naringenin  (EXP,ISO)
(Z)-ligustilide  (EXP,ISO)
1-Hydroxypyrene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2',4,4',6'-tetrahydroxychalcone  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrotoluene  (ISO)
2,4,6-Triphenyl-1-hexene  (EXP)
2-hydroxy-17beta-estradiol  (ISO)
2-hydroxyestrone  (ISO)
2-methoxy-17beta-estradiol  (ISO)
2-tert-butylhydroquinone  (ISO)
20-HETE  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-Hydroxybenzo[a]pyrene  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyestrone  (ISO)
4-hydroxyphenytoin  (ISO)
4-methylumbelliferone  (ISO)
4-methylumbelliferone beta-D-glucuronide  (ISO)
4-nitrophenol  (ISO)
5,7-dihydroxy-4'-methoxyflavone  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
5-methoxypsoralen  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alizarin  (ISO)
all-trans-retinol  (ISO)
alpha-tocotrienol  (ISO)
amentoflavone  (ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
androsterone  (ISO)
Anetholtrithion  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
anthraflavic acid  (ISO)
anthrarobin  (ISO)
apigenin  (ISO)
arachidonic acid  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzamidoxime  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
bergomottin  (ISO)
beta-naphthoflavone  (EXP,ISO)
beta-tocopherol  (ISO)
beta-tocotrienol  (ISO)
bilirubin IXalpha  (ISO)
biochanin A  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Boldine  (ISO)
Bropirimine  (ISO)
buprenorphine  (ISO)
buta-1,3-diene  (EXP)
butylated hydroxyanisole  (EXP,ISO)
butyric acid  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
calycosin  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carvedilol  (ISO)
chalcones  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (ISO)
chrysen-6-ol  (ISO)
chrysin  (ISO)
ciprofibrate  (EXP)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
Clofop  (ISO)
clomipramine  (ISO)
clotrimazole  (ISO)
clozapine  (ISO)
coumarins  (ISO)
coumestrol  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (ISO)
daidzein  (ISO)
decabromodiphenyl ether  (ISO)
delta-tocopherol  (ISO)
delta-tocotrienol  (ISO)
dexamethasone  (EXP,ISO)
diallyl disulfide  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
dibenzo[a,l]pyrene  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
diflunisal  (ISO)
dioxygen  (ISO)
dipyridamole  (ISO)
doxorubicin  (ISO)
emodin  (ISO)
endosulfan  (ISO)
entacapone  (ISO)
epoxiconazole  (ISO)
equol  (ISO)
Estragole  (EXP)
estriol  (ISO)
estrone  (ISO)
ethoxyquin  (EXP,ISO)
etoposide  (ISO)
eugenol  (ISO)
ezetimibe  (ISO)
farnesol  (ISO)
felbamate  (ISO)
fenofibrate  (ISO)
fipronil  (EXP,ISO)
fipronil-sulfone  (ISO)
fisetin  (ISO)
flavanone  (EXP)
flavonoids  (ISO)
flumequine  (EXP)
flunitrazepam  (ISO)
flurbiprofen  (ISO)
formononetin  (ISO)
fulvestrant  (ISO)
furan  (ISO)
furosemide  (ISO)
fusidic acid  (ISO)
galangin  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gamma-tocopherol  (EXP,ISO)
gemfibrozil  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
Ginkgolide A  (ISO)
ginkgolide B  (ISO)
ginsenoside Rg1  (ISO)
glabridin  (ISO)
Grepafloxacin  (ISO)
griseofulvin  (EXP)
hyperforin  (ISO)
ibuprofen  (EXP,ISO)
imipramine  (ISO)
imperatorin  (ISO)
indometacin  (ISO)
indoxyl sulfate  (ISO)
irinotecan  (ISO)
isoflavones  (EXP,ISO)
isoliquiritigenin  (ISO)
kaempferol  (EXP,ISO)
ketoconazole  (ISO)
ketoprofen  (ISO)
L-ethionine  (ISO)
labetalol  (ISO)
lansoprazole  (ISO)
leflunomide  (ISO)
lithocholic acid  (EXP)
luteolin  (ISO)
LY294002  (ISO)
mangiferin  (ISO)
masoprocol  (ISO)
Meclizine  (EXP)
MeIQx  (ISO)
metazachlor  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
MK 571  (ISO)
morin  (ISO)
morphine  (ISO)
moxifloxacin  (ISO)
N-hydroxy-PhIP  (ISO)
N-nitrosodiethylamine  (ISO)
naproxen  (ISO)
Niflumic acid  (ISO)
nilotinib  (ISO)
notoginsenoside R1  (EXP,ISO)
obeticholic acid  (ISO)
ofloxacin  (ISO)
oltipraz  (EXP)
omeprazole  (ISO)
ortho-Aminoazotoluene  (EXP)
oxycodone  (ISO)
paclitaxel  (EXP)
pantoprazole  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorobutyric acid  (ISO)
perfluorodecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenacetin  (ISO)
phenanthrene  (EXP)
phenobarbital  (EXP,ISO)
phenylbutazone  (ISO)
phenytoin  (EXP,ISO)
PhIP  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
plumbagin  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
prochloraz  (ISO)
progesterone  (ISO)
propacetamol  (EXP)
propiconazole  (ISO)
prostaglandin B1  (ISO)
prostaglandin E2  (ISO)
prostaglandin F2alpha  (ISO)
pterostilbene  (ISO)
puerarin  (ISO)
pyrene  (EXP)
quercetin  (ISO)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
quinizarin  (ISO)
rabeprazole  (ISO)
resveratrol  (ISO)
retinyl acetate  (EXP)
rifampicin  (ISO)
ritonavir  (ISO)
robinetin  (ISO)
SB 203580  (ISO)
scopoletin  (ISO)
sevoflurane  (ISO)
Shikonin  (ISO)
silibinin  (ISO)
Sitafloxacin  (ISO)
sodium acetate trihydrate  (EXP,ISO)
sodium arsenite  (EXP)
sodium propionate  (ISO)
spironolactone  (EXP,ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
taurine  (ISO)
tebuconazole  (ISO)
tert-butyl ethyl ether  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
thyroxine  (ISO)
ticlopidine  (ISO)
tienilic acid  (ISO)
trans-piceid  (ISO)
triadimefon  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclocarban  (ISO)
triclosan  (ISO)
trifluralin  (ISO)
troglitazone  (ISO)
UDP-alpha-D-glucuronic acid  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
warfarin  (ISO)
xanthohumol  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
1. Borgna-Pignatti C, etal., Haematologica. 2003 Oct;88(10):1106-9.
2. Bortolussi G, etal., FASEB J. 2012 Mar;26(3):1052-63. Epub 2011 Nov 17.
3. Boyd MA, etal., Pharmacogenet Genomics. 2006 May;16(5):321-9.
4. Braun L, etal., Biochem J. 1998 Dec 15;336 ( Pt 3):587-92.
5. Canadian Medical Association Journal
6. Cecchin E, etal., Oncol Rep. 2004 Aug;12(2):457-62.
7. Chang PF, etal., J Pediatr. 2011 Oct;159(4):561-5. doi: 10.1016/j.jpeds.2011.03.042. Epub 2011 May 18.
8. de Vries HS, etal., J Crohns Colitis. 2011 Dec 16.
9. del Giudice EM, etal., Blood. 1999 Oct 1;94(7):2259-62.
10. Deming SL, etal., Cancer Epidemiol Biomarkers Prev. 2008 Mar;17(3):563-70.
11. Galanello R, etal., Haematologica. 1999 Feb;84(2):103-5.
12. Gantla S, etal., Am J Hum Genet. 1998 Mar;62(3):585-92.
13. Gao J, etal., Med Oncol. 2013;30(3):630. doi: 10.1007/s12032-013-0630-8. Epub 2013 Jun 20.
14. Glimelius B, etal., Pharmacogenomics J. 2011 Feb;11(1):61-71. doi: 10.1038/tpj.2010.10. Epub 2010 Feb 23.
15. Haberkorn V, etal., Pharm Res. 2003 Oct;20(10):1568-73.
16. Han JY, etal., J Clin Oncol. 2006 May 20;24(15):2237-44. Epub 2006 Apr 24.
17. Haverfield EV, etal., Blood. 2005 Feb 1;105(3):968-72. Epub 2004 Sep 23.
18. Innocenti F, etal., J Clin Oncol. 2004 Apr 15;22(8):1382-8. Epub 2004 Mar 8.
19. Jia Z and Danko I, Mol Ther. 2005 Nov;12(5):860-6. Epub 2005 Jul 12.
20. Martins R, etal., J Hum Genet. 2008;53(6):524-8. doi: 10.1007/s10038-008-0281-3. Epub 2008 Apr 5.
21. McGill MR and Jaeschke H, Pharm Res. 2013 Sep;30(9):2174-87. doi: 10.1007/s11095-013-1007-6. Epub 2013 Mar 6.
22. MGD and Homologene mouse data transfer
23. MGD data from the GO Consortium
24. Montenegro-Miranda PS, etal., Gene Ther. 2014 Feb;21(2):168-74. doi: 10.1038/gt.2013.69. Epub 2013 Nov 28.
25. Mori S, etal., Mod Rheumatol. 2011 Oct 13.
26. Moriya H, etal., Oncol Lett. 2014 Jun;7(6):2035-2040. Epub 2014 Apr 8.
27. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
28. OMIM Disease Annotation Pipeline
29. Otsuka H, etal., Breast Cancer. 2015 Jul;22(4):335-42. doi: 10.1007/s12282-013-0483-1. Epub 2013 Jul 5.
30. Pastore N, etal., Hum Gene Ther. 2012 Oct;23(10):1082-9. doi: 10.1089/hum.2012.018. Epub 2012 Aug 27.
31. Pipeline to import KEGG annotations from KEGG into RGD
32. Pipeline to import SMPDB annotations from SMPDB into RGD
33. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
34. RGD automated import pipeline for gene-chemical interactions
35. Richardson TA, etal., Drug Metab Dispos. 2006 Mar;34(3):351-3. Epub 2005 Dec 8.
36. Shatalova EG, etal., Mol Biol (Mosk). 2006 Mar-Apr;40(2):263-70.
37. Shibata T, etal., Int J Clin Oncol. 2014 Apr;19(2):391-6. doi: 10.1007/s10147-013-0562-5. Epub 2013 Apr 23.
38. Sun Q, etal., Clin Drug Investig. 2017 Dec;37(12):1125-1136. doi: 10.1007/s40261-017-0572-6.
39. Takano M, etal., Oncology. 2009;76(5):315-21. Epub 2009 Mar 20.
40. Tankanitlert J, etal., Eur J Haematol. 2008 Apr;80(4):351-5. Epub 2007 Dec 10.
41. Toietta G, etal., Proc Natl Acad Sci U S A 2005 Mar 15;102(11):3930-5. Epub 2005 Mar 7.
42. Tsai MS, etal., Toxicol Lett. 2018 Jun 15;290:97-109. doi: 10.1016/j.toxlet.2018.03.024. Epub 2018 Mar 21.
43. van der Wegen P, etal., Mol Ther. 2006 Feb;13(2):374-81. Epub 2005 Dec 5.
44. Vasavda N, etal., Br J Haematol. 2007 Jul;138(2):263-70.
45. Wang X, etal., Hepatology. 2009 Sep;50(3):815-24. doi: 10.1002/hep.23060.
46. Xie H, etal., Drug Metab Pharmacokinet. 2013;28(5):427-34. Epub 2013 Apr 2.
47. Yi YX, etal., Front Pharmacol. 2018 May 15;9:510. doi: 10.3389/fphar.2018.00510. eCollection 2018.
48. Zhang C, etal., J Int Med Res. 2018 Feb;46(2):739-751. doi: 10.1177/0300060517730174. Epub 2017 Sep 20.
49. Zhang T, etal., Genome Res 2004 Jan;14(1):79-89. Epub 2003 Dec 12.
Additional References at PubMed
PMID:1359870   PMID:1685137   PMID:7677729   PMID:7698007   PMID:7698765   PMID:8464825   PMID:8467709   PMID:8570653   PMID:8617499   PMID:8672127   PMID:8751373   PMID:8897953  
PMID:9107685   PMID:10462540   PMID:12051676   PMID:12475965   PMID:12477932   PMID:12951053   PMID:14681479   PMID:15457340   PMID:17259171   PMID:18180294   PMID:19880377   PMID:20197307  
PMID:21267068   PMID:21873635   PMID:24191041   PMID:25200869   PMID:27531557   PMID:29448836   PMID:31211694   PMID:32093886  


Genomics

Comparative Map Data
Ugt1a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39188,139,681 - 88,147,724 (+)NCBIGRCm39mm39
GRCm38188,211,959 - 88,220,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl188,211,959 - 88,218,997 (+)EnsemblGRCm38mm10GRCm38
MGSCv37190,108,534 - 90,116,577 (+)NCBIGRCm37mm9NCBIm37
MGSCv36190,043,130 - 90,050,148 (+)NCBImm8
Celera191,173,026 - 91,181,062 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.55NCBI
UGT1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2233,760,270 - 233,773,300 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2233,760,248 - 233,773,299 (+)EnsemblGRCh38hg38GRCh38
GRCh382233,760,270 - 233,773,300 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372234,668,919 - 234,681,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362234,333,658 - 234,346,684 (+)NCBINCBI36hg18NCBI36
Build 342234,450,918 - 234,463,945NCBI
Celera2228,389,552 - 228,402,577 (+)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2226,468,768 - 226,481,779 (+)NCBIHuRef
CHM1_12234,674,733 - 234,687,806 (+)NCBICHM1_1
Ugt1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0995,295,701 - 95,302,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl995,161,157 - 95,302,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,982,916 - 94,990,037 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4987,091,241 - 87,098,362 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1987,277,121 - 87,284,238 (+)NCBI
Celera986,362,434 - 86,369,556 (+)NCBICelera
Cytogenetic Map9q35NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139093727126517573Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
1357741Nidd5k_mNidd5 on KK-A<y> (mouse)Not determined15593578989935898Mouse
1357505Vtbt1_mvertebral trabecular bone trait 1 (mouse)Not determined15622705590227201Mouse
4142467Wbcq1_mwhite blood cell quantitative locus 1 (mouse)Not determined15622705590227201Mouse
1301933Insq6_minsulin QTL 6 (mouse)Not determined15668776390687918Mouse
1558717Ses1a_msalmonella enteritidis susceptibility 1a (mouse)Not determined15668776390687918Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15790219291902192Mouse
14747009Manh49_mmandible shape 49 (mouse)15790219291902192Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15795281891952921Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15795281891952921Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15795281891952921Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15857254792572799Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15857254792572799Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162907596120601949Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
1302119Cia15_mcollagen induced arthritis 15 (mouse)Not determined16584984788568379Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167300000129800000Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170205811104211835Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173227055108910684Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73687970107688108Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173687970107688108Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74477076148839837Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174952818133363199Mouse
1300821Lore1_mloss of righting induced by ethanol 1 (mouse)Not determined17557254793013355Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)176000000128600000Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)176000000148900000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177146478110608345Mouse
14697706Stsl3a_mSalmonella typhimurium susceptibility locus 3a (mouse)17750000095900000Mouse
14696693Avd2q1_mattack value day 2 QTL 1 (mouse)17900000091000000Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179930958113931066Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179930958113931066Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180267876126458780Mouse
14696692Tavq1_mtotal attack value QTL 1 (mouse)18200000088500000Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782314261147249632Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182665468135687641Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182904910116904910Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182904910116904910Mouse
25394564Skmw49_mskeletal muscle weight 49, TA (mouse)18344239888624908Mouse
11667074Led2_mlate embryonic death 2 (mouse)185768306117267351Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186556204120556204Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:185
Count of miRNA genes:167
Interacting mature miRNAs:173
Transcripts:ENSMUST00000073049
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000073049   ⟹   ENSMUSP00000072803
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl188,211,959 - 88,218,997 (+)Ensembl
RefSeq Acc Id: NM_201645   ⟹   NP_964007
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39188,139,681 - 88,147,724 (+)NCBI
GRCm38188,211,959 - 88,220,002 (+)ENTREZGENE
MGSCv37190,108,534 - 90,116,577 (+)RGD
Celera191,173,026 - 91,181,062 (+)RGD
cM Map1 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_964007   ⟸   NM_201645
- Peptide Label: precursor
- UniProtKB: Q63886 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000072803   ⟸   ENSMUST00000073049

Promoters
RGD ID:6818679
Promoter ID:MM_KWN:1560
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney,   Liver,   MEF_B4
Transcripts:NM_201645
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36190,108,304 - 90,108,804 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98898 AgrOrtholog
Ensembl Genes ENSMUSG00000089960 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000072803 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000073049 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro UDP_glucos_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP_glycos_trans_CS UniProtKB/Swiss-Prot
KEGG Report mmu:394436 UniProtKB/Swiss-Prot
MGD MGI:98898 ENTREZGENE
NCBI Gene 394436 ENTREZGENE
Pfam UDPGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB UGT1A1 RGD
PhenoGen Ugt1a1 PhenoGen
PROSITE UDPGT UniProtKB/Swiss-Prot
UniGene Mm.300095 ENTREZGENE
UniProt J7HWK0_MOUSE UniProtKB/TrEMBL
  Q63886 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q561M6 UniProtKB/Swiss-Prot
  Q6XL50 UniProtKB/Swiss-Prot