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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3935
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase family 1 member A1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt1a1increases expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of UGT1A1 mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of UGT1A1 proteinPMID:20056577 PMID:32679240
Ugt1a1increases expressionISOUgt1a1 (Mus musculus)6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of UGT1A1 mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of UGT1A7 mRNAPMID:17964624
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