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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3935
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase family 1 member A1
Acc ID: CHEBI:39669
Term: diflunisal
Definition: An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
Chemical ID: MESH:D004061
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt1a1decreases activityISOUGT1A1 (Homo sapiens)6480464CTDDiflunisal results in decreased activity of UGT1A1 proteinPMID:15593333
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