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Gene: UGT1A1 (UDP glucuronosyltransferase family 1 member A1) Homo sapiens
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Symbol: UGT1A1
Name: UDP glucuronosyltransferase family 1 member A1
Description: Exhibits several functions, including glucuronosyltransferase activity; protein dimerization activity; and retinoic acid binding activity. Involved in cellular glucuronidation; flavone metabolic process; and negative regulation of cellular glucuronidation. Localizes to the endoplasmic reticulum. Implicated in several diseases, including bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; female reproductive organ cancer (multiple); and hepatitis B.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BILIQTL1; bilirubin UDP-glucuronosyltranserase; bilirubin UDP-glucuronosyltransferase 1-1; bilirubin UDP-glucuronosyltransferase isozyme 1; bilirubin-specific UDPGT isozyme 1; GNT1; HUG-BR1; UDP glucuronosyltransferase 1 family, polypeptide A1; UDP glycosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1A1; UDPGT; UDPGT 1-1; UGT-1A; UGT1; UGT1*1; UGT1-01; UGT1.1; UGT1A
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2233,760,248 - 233,773,299 (+)Ensembl
GRCh382233,760,270 - 233,773,300 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372234,668,919 - 234,681,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362234,333,658 - 234,346,684 (+)NCBINCBI36hg18NCBI36
Build 342234,450,918 - 234,463,945NCBI
Celera2228,389,552 - 228,402,577 (+)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2226,468,768 - 226,481,779 (+)NCBIHuRef
CHM1_12234,674,733 - 234,687,806 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on UGT1A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350018
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.