Strain Report - Rat Genome Database

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Strain: Gunn-Ugt1a1j/BluHsdRrrc

Symbol: Gunn-Ugt1a1j/BluHsdRrrc
Strain: Gunn-Ugt1a1j
Substrain: BluHsdRrrc
Full Name: Gunn rat
RGD ID: 6482254
Citation ID: RRID:RRRC_00341
Ontology ID: RS:0000267
Alleles: Ugt1a1j
Also Known As: Gunn-Ugt1a1jBluHsdRrrc; Gunn-Ugt1a1jBluHsdRrrc; Gunn-Ugt1a1j/BluHsdRrrc; Gunn-Ugt1a1^[j]/BluHsdRrrc
Type: mutant
Available Source: Rat Resource and Research Center
Origination: Rat Resource and Research Center
Description: This mutation was first observed in normal Wistar albino rats in a breeding colony at Cannaught Laboratories in 1934. Jaundice was evident at birth or shortly after and was persistant throughout life.
Coat Color: Albino
Last Known Status: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-09-15)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,805,660 - 88,805,660RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0995,300,017 - 95,300,017RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0994,982,916 - 94,990,037RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4987,091,241 - 87,098,362RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Ugt1a1j-var1 chr9 88805660 88805660 G - deletion mRatBN7.2
Ugt1a1j-var1 chr9 95300017 95300017 G - deletion Rnor_6.0

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other This strain carries a recessive spontaneous mutant allele in which a single base (G) has been deleted in exon 4 of the Ugt1a1 gene. Microsatellite analysis of the background of this strain indicates that the Wistar stock background is now an inbred strain background which is designated as Gunn. 2292495
strain_other This strain carries a spontaneous mutation in which a single base (G) has been deleted in exon 4 of the Ugt1a1 gene. 2292495
strain_reproduction Homozygous females are sterile. Typical breeding scheme is homozygous or heterozygous male mated to heterozygous female. Higher pup numbers are seen with heterozygous x heterozygous breeding scheme. 2292495

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-15 Gunn-Ugt1a1j/BluHsdRrrc  Gunn rat  Gunn-Ugt1a1jBluHsdRrrc  Gunn rat  Symbol updated 68687 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00341 RGD