Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | autism spectrum disorder | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Autism spectrum disorder | ClinVar | PMID:25741868, PMID:27569545 | autistic disorder | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Autism | ClinVar | PMID:21681106, PMID:30208311 | Bardet-Biedl syndrome | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Bardet-Biedl syndrome | ClinVar | PMID:25741868 | chromosome 22q11.2 deletion syndrome, distal | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Chromosome 22q11.2 deletion syndrome, distal | ClinVar | PMID:31690835 | chromosome 22q11.2 microduplication syndrome | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Chromosome 22q11.2 microduplication syndrome | ClinVar | PMID:31690835 | DiGeorge syndrome | | ISO | RGD:737102 | 8554872 | ClinVar more ... | ClinVar | PMID:21921585 more ... | dilated cardiomyopathy | | ISO | RGD:737102 | 8554872 | ClinVar more ... | ClinVar | PMID:28492532 | dilated cardiomyopathy | | ISO | RGD:737102 | 8554872 | ClinVar more ... | ClinVar | PMID:25741868, PMID:28492532 | Dwarfism | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Short stature | ClinVar | PMID:25741868 | epilepsy | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Epilepsy | ClinVar | | familial hypertrophic cardiomyopathy | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Primary familial hypertrophic cardiomyopathy | ClinVar | PMID:28492532 | genetic disease | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | Glucocorticoid Deficiency 5 | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Glucocorticoid deficiency 5 | ClinVar | PMID:25741868, PMID:28492532 | hemorrhagic disease | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Abnormal bleeding | ClinVar | PMID:25741868, PMID:31064749 | immunodeficiency 51 | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: CANDIDIASIS more ... | ClinVar | PMID:24552284 more ... | intellectual disability | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Intellectual disability | ClinVar | | megacolon | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Megacolon | ClinVar | PMID:21681106 | Neurodevelopmental Disorders | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Neurodevelopmental disorder | ClinVar | PMID:25741868 | panic disorder | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: CATECHOL-O-METHYLTRANSFERASE POLYMORPHISM | ClinVar | PMID:10395222 more ... | Polyarteritis Nodosa, Childhood-Onset | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: VASCULITIS more ... | ClinVar | PMID:24552284 more ... | primary immunodeficiency disease | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Inherited Immunodeficiency Diseases | ClinVar | PMID:25741868 | schizophrenia | | ISO | RGD:737102 | 8554872 | ClinVar more ... | ClinVar | PMID:10395222 more ... | velocardiofacial syndrome | | ISO | RGD:737102 | 8554872 | ClinVar more ... | ClinVar | PMID:25741868 | Venous Thrombosis | | ISO | RGD:737102 | 8554872 | ClinVar Annotator: match by term: Deep venous thrombosis | ClinVar | PMID:25741868, PMID:31064749 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups. | Al-Hendy A and Salama SA, J Soc Gynecol Investig. 2006 Feb;13(2):136-44. |
| 2. | Association between the COMT locus and obsessive-compulsive disorder in females but not males. | Alsobrook JP 2nd, etal., Am J Med Genet 2002 Jan 8;114(1):116-20. |
| 3. | Immunohistochemical localization of catechol methyltransferase in normal and cancerous breast tissues of mice and rats. | Amin AM, etal., J Natl Cancer Inst. 1983 Feb;70(2):337-42. |
| 4. | Orientation and cellular distribution of membrane-bound catechol-O-methyltransferase in cortical neurons: implications for drug development. | Chen J, etal., J Biol Chem. 2011 Oct 7;286(40):34752-60. doi: 10.1074/jbc.M111.262790. Epub 2011 Aug 16. |
| 5. | Chronic antipsychotics treatment regulates MAOA, MAOB and COMT gene expression in rat frontal cortex. | Chen ML and Chen CH, J Psychiatr Res. 2007 Jan-Feb;41(1-2):57-62. Epub 2005 Jun 17. |
| 6. | Chronic treatment with aripiprazole induces differential gene expression in the rat frontal cortex. | Cheng MC, etal., Int J Neuropsychopharmacol. 2007 Sep 17;:1-10. |
| 7. | Evaluation of genetic variations in the androgen and estrogen metabolic pathways as risk factors for sporadic and familial prostate cancer. | Cunningham JM, etal., Cancer Epidemiol Biomarkers Prev. 2007 May;16(5):969-78. |
| 8. | The catechol O-methyltransferase Val158Met polymorphism and herpes simplex virus type 1 infection are risk factors for cognitive impairment in bipolar disorder: additive gene-environmental effects in a complex human psychiatric disorder. | Dickerson FB, etal., Bipolar Disord. 2006 Apr;8(2):124-32. |
| 9. | Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms. | Dubey RK, etal., Biochem Biophys Res Commun. 2000 Nov 11;278(1):27-33. |
| 10. | Determination of differential activities of soluble and membrane-bound catechol-O-methyltransferase in tissues and erythrocytes. | Ellingson T, etal., J Chromatogr B Biomed Sci Appl. 1999 Jun 11;729(1-2):347-53. |
| 11. | Catechol-O-methyltransferase genotype (Val158met) modulates cancer-related fatigue and pain sensitivity in breast cancer survivors. | Fernandez-de-las-Penas C, etal., Breast Cancer Res Treat. 2012 Jun;133(2):405-12. doi: 10.1007/s10549-011-1757-y. Epub 2011 Sep 4. |
| 12. | Catechol-O-methyltransferase Val158Met polymorphism (rs4680) is associated with pain in multiple sclerosis. | Fernández-de-las-Peñas C, etal., J Pain. 2013 Dec;14(12):1719-23. doi: 10.1016/j.jpain.2013.09.007. Epub 2013 Sep 28. |
| 13. | Polymorphisms of the estrogen-metabolizing genes CYP17 and catechol-O-methyltransferase and risk of epithelial ovarian cancer. | Garner EI, etal., Cancer Res. 2002 Jun 1;62(11):3058-62. |
| 14. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 15. | Catechol-O-methyltransferase genotype is associated with plasma total homocysteine levels and may increase venous thrombosis risk. | Gellekink H, etal., Thromb Haemost. 2007 Dec;98(6):1226-31. |
| 16. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
| 17. | Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. | Gogos JA, etal., Proc Natl Acad Sci U S A 1998 Aug 18;95(17):9991-6. |
| 18. | Catechol-O-methyltransferase polymorphism is not associated with ovarian cancer risk. | Goodman JE, etal., Cancer Epidemiol Biomarkers Prev. 2000 Dec;9(12):1373-6. |
| 19. | Increased catechol-O-methyltransferase activity and protein expression in OX-42-positive cells in the substantia nigra after lipopolysaccharide microinfusion. | Helkamaa T, etal., Neurochem Int. 2007 Nov-Dec;51(6-7):412-23. Epub 2007 May 6. |
| 20. | Measurement of catechol-O-methyltransferase activity in the brain of Dahl salt-sensitive rats. | Hirano Y, etal., Biol Pharm Bull. 2007 Nov;30(11):2178-80. |
| 21. | Suppression of catechol-O-methyltransferase activity through blunting of alpha2-adrenoceptor can explain hypertension in Dahl salt-sensitive rats. | Hirano Y, etal., Hypertens Res. 2007 Mar;30(3):269-78. |
| 22. | A multigenic study on breast cancer risk associated with genetic polymorphisms of ER Alpha, COMT and CYP19 gene in BRCA1/BRCA2 negative Shanghai women with early onset breast cancer or affected relatives. | Hu Z, etal., J Cancer Res Clin Oncol. 2007 Dec;133(12):969-78. Epub 2007 Jun 12. |
| 23. | Activation of catechol-O-methyltransferase in astrocytes stimulates homocysteine synthesis and export to neurons. | Huang G, etal., Glia. 2005 Jul;51(1):47-55. |
| 24. | Clinical symptoms in fibromyalgia are associated to catechol-O-methyltransferase (COMT) gene Val158Met polymorphism. | Inanir A, etal., Xenobiotica. 2014 Oct;44(10):952-6. doi: 10.3109/00498254.2014.913083. Epub 2014 Apr 24. |
| 25. | Diagnostic potential in bladder cancer of a panel of tumor markers (calreticulin, gamma -synuclein, and catechol-o-methyltransferase) identified by proteomic analysis. | Iwaki H, etal., Cancer Sci. 2004 Dec;95(12):955-61. |
| 26. | Catechol-O-methyltransferase (COMT) inhibition reduces spinal nociceptive activity. | Jacobsen LM, etal., Neurosci Lett. 2010 Apr 12;473(3):212-5. doi: 10.1016/j.neulet.2010.02.049. Epub 2010 Feb 26. |
| 27. | Dopamine D3 receptor Ser9Gly and catechol-o-methyltransferase Val158Met polymorphisms and acute pain in sickle cell disease. | Jhun E, etal., Anesth Analg. 2014 Nov;119(5):1201-7. doi: 10.1213/ANE.0000000000000382. |
| 28. | Inhibitors of catechol-O-methyltransferase sensitize mice to pain. | Kambur O, etal., Br J Pharmacol. 2010 Dec;161(7):1553-65. doi: 10.1111/j.1476-5381.2010.00999.x. |
| 29. | Association of genetic polymorphisms of ACADSB and COMT with human hypertension. | Kamide K, etal., J Hypertens. 2007 Jan;25(1):103-10. |
| 30. | Catechol-O-methyltransferase (COMT) in rat brain: immunoelectron microscopic study with an antiserum against rat recombinant COMT protein. | Karhunen T, etal., Neurosci Lett. 1995 Feb 24;187(1):57-60. |
| 31. | KEGG: Kyoto Encyclopedia of Genes and Genomes | KEGG |
| 32. | High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. | Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7 |
| 33. | Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition. | Laatikainen LM, etal., J Psychopharmacol. 2012 Dec;26(12):1561-8. doi: 10.1177/0269881112454228. Epub 2012 Jul 19. |
| 34. | Microarray analysis of differentially expressed genes associated with human ovarian cancer. | Lee BC, etal., Int J Oncol. 2004 Apr;24(4):847-51. |
| 35. | A functional single-nucleotide polymorphism in the catechol-O-methyltransferase gene alter vitiligo risk in a Chinese population. | Li K, etal., Arch Dermatol Res. 2009 Oct;301(9):681-7. doi: 10.1007/s00403-008-0920-8. Epub 2008 Dec 28. |
| 36. | COMT genotype and response to cognitive remediation in schizophrenia. | Lindenmayer JP, etal., Schizophr Res. 2015 Oct;168(1-2):279-84. doi: 10.1016/j.schres.2015.07.037. Epub 2015 Aug 6. |
| 37. | Genetic polymorphisms in estrogen-metabolizing genes and breast cancer survival. | Long JR, etal., Pharmacogenet Genomics. 2007 May;17(5):331-8. |
| 38. | Early administration of entacapone prevents levodopa-induced motor fluctuations in hemiparkinsonian rats. | Marin C, etal., Exp Neurol. 2005 Mar;192(1):184-93. |
| 39. | Coadministration of entacapone with levodopa attenuates the severity of dyskinesias in hemiparkinsonian rats. | Marin C, etal., Mov Disord. 2006 May;21(5):646-53. |
| 40. | Progression of human breast cancers to the metastatic state is linked to genotypes of catechol-O-methyltransferase. | Matsui A, etal., Cancer Lett. 2000 Mar 13;150(1):23-31. |
| 41. | Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. | Matsumoto M, etal., Neuroscience 2003;116(1):127-37. |
| 42. | Analysis of oxidative stress status, catalase and catechol-o-methyltransferase polymorphisms in egyptian vitiligo patients. | Mehaney DA, etal., PLoS One. 2014 Jun 10;9(6):e99286. doi: 10.1371/journal.pone.0099286. eCollection 2014. |
| 43. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 44. | Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. | Nackley AG, etal., Pain. 2007 Apr;128(3):199-208. Epub 2006 Nov 7. |
| 45. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 46. | Regulation of dopamine-induced natriuresisby the dopamine-metabolizing enzyme catechol-O-methyltransferase. | Odlind C, etal., Exp Nephrol. 1999 Jul-Aug;7(4):314-22. |
| 47. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
| 48. | Online Mendelian Inheritance in Man, OMIM (TM). | Online Mendelian Inheritance in Man, OMIM (TM). |
| 49. | The Effect of Single Dose Methylphenidate on Neurometabolites according to COMT Gene Val158Met Polymorphism in the Patient with Attention Deficit Hyperactivity Disorder: A Study Using Magnetic Resonance Spectroscopy. | Ozturk O, etal., Clin Psychopharmacol Neurosci. 2016 May 31;14(2):184-93. doi: 10.9758/cpn.2016.14.2.184. |
| 50. | Molecular modeling and metabolic studies of the interaction of catechol-O-methyltransferase and a new nitrocatechol inhibitor. | Palma PN, etal., Drug Metab Dispos 2003 Mar;31(3):250-8. |
| 51. | Catechol-o-methyltransferase and methoxyestradiols participate in the intraoviductal nongenomic pathway through which estradiol accelerates egg transport in cycling rats. | Parada-Bustamante A, etal., Biol Reprod. 2007 Dec;77(6):934-41. Epub 2007 Aug 15. |
| 52. | Association analysis of COMT polymorphisms with schizophrenia and smooth pursuit eye movement abnormality. | Park BL, etal., J Hum Genet. 2009 Dec;54(12):709-12. doi: 10.1038/jhg.2009.102. Epub 2009 Oct 30. |
| 53. | Developmental changes in the activity of catechol-O-methyl transferase in rat and rabbit fetuses. | Parvez H, etal., J Neural Transm. 1979;44(1-2):65-75. |
| 54. | Methyl conjugation in uraemia: catechol-O-methyltransferase. | Pazmino PA and Weinshilboum RM, Br J Clin Pharmacol. 1980 Nov;10(5):509-18. |
| 55. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 56. | SMPDB Annotation Import Pipeline | Pipeline to import SMPDB annotations from SMPDB into RGD |
| 57. | The blood-brain barrier-permeable catechol-O-methyltransferase inhibitor dinitrocatechol suppresses experimental autoimmune encephalomyelitis. | Polak PE, etal., J Neuroimmunol. 2014 Nov 15;276(1-2):135-41. doi: 10.1016/j.jneuroim.2014.09.004. Epub 2014 Sep 16. |
| 58. | Attention-deficit/hyperactivity disorder phenotype is influenced by a functional catechol-O-methyltransferase variant. | Pálmason H, etal., J Neural Transm (Vienna). 2010 Feb;117(2):259-67. doi: 10.1007/s00702-009-0338-2. Epub 2009 Nov 28. |
| 59. | Association between autism spectrum disorder in individuals with velocardiofacial (22q11.2 deletion) syndrome and PRODH and COMT genotypes. | Radoeva PD, etal., Psychiatr Genet. 2014 Dec;24(6):269-72. doi: 10.1097/YPG.0000000000000062. |
| 60. | Traumatic brain injury stimulates hippocampal catechol-O-methyl transferase expression in microglia. | Redell JB and Dash PK, Neurosci Lett. 2007 Feb 8;413(1):36-41. Epub 2006 Dec 15. |
| 61. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 62. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 63. | Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas. | Salama SA, etal., Fertil Steril. 2006 Jul;86(1):259-62. Epub 2006 May 26. |
| 64. | Lower levels of urinary 2-hydroxyestrogens in polycystic ovary syndrome. | Salih S, etal., J Clin Endocrinol Metab. 2007 Aug;92(8):3285-91. Epub 2007 May 29. |
| 65. | Molecular cloning and characterization of rat liver catechol-O-methyltransferase. | Salminen M, etal., Gene 1990 Sep 14;93(2):241-7. |
| 66. | Multiple promoters of catechol-O-methyltransferase gene are selectively inactivated by CpG hypermethylation in endometrial cancer. | Sasaki M, etal., Cancer Res. 2003 Jun 15;63(12):3101-6. |
| 67. | Complex estrogenic regulation of catechol-O-methyltransferase (COMT) in rats. | Schendzielorz N, etal., J Physiol Pharmacol. 2011 Aug;62(4):483-90. |
| 68. | A highly significant association between a COMT haplotype and schizophrenia. | Shifman S, etal., Am J Hum Genet 2002 Dec;71(6):1296-302. Epub 2002 Oct 25. |
| 69. | Quercetin potentiates L-Dopa reversal of drug-induced catalepsy in rats: possible COMT/MAO inhibition. | Singh A, etal., Pharmacology. 2003 Jun;68(2):81-8. |
| 70. | Catechol-O-methyltransferase activity in psoriasis patients treated with psoralen plus ultraviolet A therapy. | Souteiro P, etal., Photodermatol Photoimmunol Photomed. 2013 Oct;29(5):227-32. doi: 10.1111/phpp.12058. |
| 71. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 72. | The Val158Met polymorphism of the catechol-O-methyltransferase gene is associated with the PSA-progression-free survival in prostate cancer patients treated with estramustine phosphate. | Suzuki M, etal., Eur Urol. 2005 Nov;48(5):752-9. Epub 2005 Aug 1. |
| 73. | Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution. | Szpirer C, etal., Mamm Genome 1998 Sep;9(9):721-34 |
| 74. | Catechol-O-methyltransferase gene polymorphisms in benign prostatic hyperplasia and sporadic prostate cancer. | Tanaka Y, etal., Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):238-44. |
| 75. | Polymorphisms of catechol-O-methyltransferase in men with renal cell cancer. | Tanaka Y, etal., Cancer Epidemiol Biomarkers Prev. 2007 Jan;16(1):92-7. |
| 76. | Production of rat soluble and membrane-bound catechol O-methyltransferase forms from bifunctional mRNAs. | Tenhunen J and Ulmanen I, Biochem J 1993 Dec 15;296 ( Pt 3):595-600. |
| 77. | The catechol-O-methyltransferase (COMT) Val158Met polymorphism moderates the effect of antenatal stress on childhood behavioural problems: longitudinal evidence across multiple ages. | Thompson JM, etal., Dev Med Child Neurol. 2012 Feb;54(2):148-54. doi: 10.1111/j.1469-8749.2011.04129.x. Epub 2011 Nov 9. |
| 78. | Reduced membrane-bound catechol-O-methyltransferase in the liver of spontaneously hypertensive rats. | Tsunoda M, etal., Hypertens Res. 2003 Nov;26(11):923-7. |
| 79. | Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. | Tunbridge EM, etal., J Neurosci. 2004 Jun 9;24(23):5331-5. |
| 80. | Polymorphisms in catechol-O-methyltransferase and cytochrome p450 subfamily 19 genes predispose towards Madurella mycetomatis-induced mycetoma susceptibility. | van de Sande WW, etal., Med Mycol. 2010 Nov;48(7):959-68. doi: 10.3109/13693781003636680. |
| 81. | Decrease in catechol-O-methyltransferase activity in the liver of streptozotocin-induced diabetic rats. | Wang JP, etal., Clin Exp Pharmacol Physiol. 2002 May-Jun;29(5-6):419-22. |
| 82. | Genetic variation in catechol-O-methyltransferase (COMT) and obesity in the prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial. | Wang SS, etal., Hum Genet. 2007 Aug;122(1):41-9. Epub 2007 May 12. |
| 83. | Expression of cytochrome P450 1B1 and catechol-O-methyltransferase in breast tissue and their associations with breast cancer risk. | Wen W, etal., Cancer Epidemiol Biomarkers Prev. 2007 May;16(5):917-20. |
| 84. | Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats. | Wentz MJ, etal., Reproduction. 2007 Dec;134(6):831-9. |
| 85. | Identification of liver proteins and their roles associated with carbon tetrachloride-induced hepatotoxicity. | Wong LL, etal., Hum Exp Toxicol. 2011 Sep;30(9):1369-81. doi: 10.1177/0960327110391388. Epub 2010 Dec 7. |
| 86. | No association between catechol-O-methyltransferase (COMT) genotype and attention deficit hyperactivity disorder (ADHD) in Japanese children. | Yatsuga C, etal., Brain Dev. 2014 Aug;36(7):620-5. doi: 10.1016/j.braindev.2013.08.006. Epub 2013 Sep 12. |
| 87. | COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa. | Yilmaz Z, etal., Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 1;35(4):948-52. doi: 10.1016/j.pnpbp.2011.01.012. Epub 2011 Feb 12. |
| 88. | [Polymorphism of catechol-O-methyltransferase gene in relation to the risk of endometrial cancer] | Zhao XM, etal., Zhonghua Fu Chan Ke Za Zhi. 2007 Feb;42(2):116-9. |
| 89. | [Polymorphisms of CYP1B1 and COMT in breast and endometrial cancer]. | Zimarina TC, etal., Mol Biol (Mosk). 2004 May-Jun;38(3):386-93. |
Additional References at PubMed
| PMID:1765063 | PMID:8127373 | PMID:9520487 | PMID:10785817 | PMID:11559542 | PMID:12237326 | PMID:15167541 | PMID:15489334 | PMID:15645182 | PMID:16396499 | PMID:16508109 | PMID:18614015 |
| PMID:18831714 | PMID:19056347 | PMID:19056867 | PMID:19111934 | PMID:19909795 | PMID:19930170 | PMID:19946888 | PMID:19966533 | PMID:20374420 | PMID:21116937 | PMID:21428728 | PMID:21851556 |
| PMID:22071171 | PMID:22384243 | PMID:23376485 | PMID:23533145 | PMID:23863468 | PMID:24727346 | PMID:25560240 | PMID:27215035 | PMID:33048315 | PMID:33503461 | PMID:34725639 |
Genomics
Comparative Map Data
| Comt (Rattus norvegicus - Norway rat) |
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| COMT (Homo sapiens - human) |
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| Comt (Mus musculus - house mouse) |
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| Comt (Chinchilla lanigera - long-tailed chinchilla) |
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| COMT (Pan paniscus - bonobo/pygmy chimpanzee) |
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| COMT (Canis lupus familiaris - dog) |
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| Comt (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| COMT (Sus scrofa - pig) |
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| COMT (Chlorocebus sabaeus - green monkey) |
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| Comt (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Comt
105 total Variants 
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