Dpp4 (dipeptidylpeptidase 4) - Rat Genome Database

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Gene: Dpp4 (dipeptidylpeptidase 4) Rattus norvegicus
Analyze
Symbol: Dpp4
Name: dipeptidylpeptidase 4
RGD ID: 2515
Description: Exhibits several functions, including collagen binding activity; dipeptidyl-peptidase activity; and identical protein binding activity. Involved in establishment of localization; proteolysis; and regulation of T cell mediated immunity. Localizes to several cellular components, including Golgi apparatus; cell surface; and endoplasmic reticulum. Human ortholog(s) of this gene implicated in Middle East respiratory syndrome and type 2 diabetes mellitus. Orthologous to human DPP4 (dipeptidyl peptidase 4); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bile canaliculus domain-specific membrane glycoprotein; CD26; Dipeptidyl peptidase 4; dipeptidyl peptidase IV; DPP IV; DPPIV; GP110 glycoprotein; T-cell activation antigen CD26
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Dpp4DPPIV  
Genetic Models: DA.F344-Dpp4DPPIV/SvH F344-Dpp4DPPIV-/DchcHsdRrrc
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2346,962,243 - 47,043,870 (-)NCBI
Rnor_6.0 Ensembl348,291,055 - 48,372,672 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0348,291,055 - 48,372,672 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0354,957,146 - 55,038,628 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4344,279,255 - 44,360,283 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1344,175,626 - 44,256,655 (-)NCBI
Celera346,603,336 - 46,685,074 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-dichloroaniline  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
adenosine  (ISO)
aflatoxin B1  (ISO)
alogliptin  (EXP,ISO)
amiodarone  (EXP)
amphetamine  (EXP)
anagliptin  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsenic acid  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzbromarone  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
ciprofibrate  (EXP)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (EXP)
diarsenic trioxide  (ISO)
dichlorine  (EXP)
dicrotophos  (ISO)
dioxygen  (ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
formaldehyde  (EXP,ISO)
glafenine  (EXP)
Heptachlor epoxide  (ISO)
hydrazine  (ISO)
isoflavones  (ISO)
L-ascorbic acid  (ISO)
L-ethionine  (EXP)
lead diacetate  (ISO)
linagliptin  (EXP)
lucanthone  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
omeprazole  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
pyrroles  (ISO)
quercetin  (ISO)
rimonabant  (ISO)
rotenone  (EXP)
saxagliptin  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
streptozocin  (EXP)
tacrolimus hydrate  (EXP)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
Triptolide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
ursodeoxycholic acid  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
venlafaxine hydrochloride  (EXP)
vildagliptin  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
Voglibose  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. Algaissi A, etal., J Infect Dis. 2019 Feb 15;219(5):829-835. doi: 10.1093/infdis/jiy574.
2. Dobers J, etal., Eur J Biochem. 2000 Aug;267(16):5093-100.
3. Fan H, etal., Eur J Biochem. 1997 May 15;246(1):243-51.
4. Foley JE and Sreenan S, Horm Metab Res. 2009 Aug 24.
5. Frerker N, etal., Clin Chem Lab Med. 2009;47(3):275-87. doi: 10.1515/CCLM.2009.064.
6. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. GOA data from the GO Consortium
8. Hong W and Doyle D, Proc Natl Acad Sci U S A 1987 Nov;84(22):7962-6.
9. Iwata-Yoshikawa N, etal., J Virol. 2019 Mar 5;93(6). pii: JVI.01818-18. doi: 10.1128/JVI.01818-18. Print 2019 Mar 15.
10. Karl T, etal., Physiol Behav. 2003 Oct;80(1):123-34.
11. Kim J, etal., J Microbiol Biotechnol. 2020 Mar 28;30(3):427-438. doi: 10.4014/jmb.1910.10055.
12. Kim SJ, etal., Diabetes. 2009 Mar;58(3):641-51. Epub 2008 Dec 10.
13. Krupina NA, etal., Bull Exp Biol Med. 2006 Nov;142(5):554-6.
14. Kruschinski C, etal., Clin Exp Immunol. 2005 Jan;139(1):17-24.
15. Loster K, etal., Biochem Biophys Res Commun. 1995 Dec 5;217(1):341-8.
16. Ludwig K, etal., Biochem Biophys Res Commun. 2003 Apr 25;304(1):73-7.
17. MGD data from the GO Consortium
18. Mu J, etal., Eur J Pharmacol. 2009 Sep 16.
19. NCBI rat LocusLink and RefSeq merged data July 26, 2002
20. Ogata S, etal., J Biol Chem 1989 Feb 25;264(6):3596-601.
21. RGD automated data pipeline
22. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. RGD automated import pipeline for gene-chemical interactions
24. Richard E, etal., J Biol Chem 2002 May 31;277(22):19720-6.
25. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
26. Yasuda N, etal., Life Sci 2002 May 31;71(2):227-38.
Additional References at PubMed
PMID:1347701   PMID:1970322   PMID:1974258   PMID:3182821   PMID:7594462   PMID:7905271   PMID:8100523   PMID:8101391   PMID:8798518   PMID:10593948   PMID:10900005   PMID:11487543  
PMID:11772392   PMID:12068294   PMID:12675219   PMID:12675233   PMID:12716896   PMID:14684150   PMID:15052268   PMID:15448155   PMID:15584901   PMID:16478473   PMID:16651416   PMID:16670267  
PMID:16712972   PMID:16802131   PMID:16962474   PMID:17010607   PMID:17175274   PMID:17287217   PMID:17549790   PMID:17583752   PMID:17897319   PMID:18047624   PMID:18077600   PMID:18538760  
PMID:18931022   PMID:18940185   PMID:18978811   PMID:19056867   PMID:19199708   PMID:19501934   PMID:19540879   PMID:19804410   PMID:19876009   PMID:19946888   PMID:20153005   PMID:20458337  
PMID:20560982   PMID:20887754   PMID:21139073   PMID:21362503   PMID:21423176   PMID:21982785   PMID:22001206   PMID:22373413   PMID:22802229   PMID:22918684   PMID:23033273   PMID:23035207  
PMID:23184393   PMID:23359639   PMID:23361237   PMID:23376485   PMID:23408696   PMID:23486063   PMID:23533145   PMID:23535306   PMID:23677473   PMID:23832365   PMID:23894014   PMID:24357522  
PMID:24416433   PMID:24874705   PMID:25122001   PMID:25635612   PMID:25656369   PMID:25823534   PMID:25936515   PMID:26187356   PMID:26259714   PMID:26359413   PMID:26399925   PMID:27083282  
PMID:27198182   PMID:27238050   PMID:27525674   PMID:28372289   PMID:28895067   PMID:29472575   PMID:29677638   PMID:30977110   PMID:31089745   PMID:32542696  


Genomics

Comparative Map Data
Dpp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2346,962,243 - 47,043,870 (-)NCBI
Rnor_6.0 Ensembl348,291,055 - 48,372,672 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0348,291,055 - 48,372,672 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0354,957,146 - 55,038,628 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4344,279,255 - 44,360,283 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1344,175,626 - 44,256,655 (-)NCBI
Celera346,603,336 - 46,685,074 (-)NCBICelera
Cytogenetic Map3q21NCBI
DPP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2161,992,245 - 162,074,394 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2161,992,245 - 162,074,215 (-)EnsemblGRCh38hg38GRCh38
GRCh382161,992,245 - 162,074,215 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372162,848,755 - 162,930,725 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362162,557,001 - 162,639,298 (-)NCBINCBI36hg18NCBI36
Build 342162,674,263 - 162,756,559NCBI
Celera2156,458,999 - 156,541,354 (-)NCBI
Cytogenetic Map2q24.2NCBI
HuRef2154,730,637 - 154,813,409 (-)NCBIHuRef
CHM1_12162,854,656 - 162,936,956 (-)NCBICHM1_1
Dpp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39262,160,417 - 62,242,635 (-)NCBIGRCm39mm39
GRCm39 Ensembl262,160,417 - 62,242,575 (-)Ensembl
GRCm38262,330,073 - 62,412,315 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl262,330,073 - 62,412,231 (-)EnsemblGRCm38mm10GRCm38
MGSCv37262,168,130 - 62,250,288 (-)NCBIGRCm37mm9NCBIm37
MGSCv36262,132,579 - 62,212,921 (-)NCBImm8
Celera264,022,145 - 64,102,355 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map235.85NCBI
Dpp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544911,795,536 - 11,875,412 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544911,795,994 - 11,873,408 (+)NCBIChiLan1.0ChiLan1.0
DPP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B166,654,659 - 166,736,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B166,654,659 - 166,736,588 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B49,285,685 - 49,368,056 (-)NCBIMhudiblu_PPA_v0panPan3
DPP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1367,398,713 - 7,472,554 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl367,399,643 - 7,454,204 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha367,540,277 - 7,619,076 (-)NCBI
ROS_Cfam_1.0367,528,186 - 7,606,978 (-)NCBI
UMICH_Zoey_3.1367,543,394 - 7,622,160 (-)NCBI
UNSW_CanFamBas_1.0367,588,175 - 7,666,856 (-)NCBI
UU_Cfam_GSD_1.0367,695,776 - 7,774,177 (-)NCBI
Dpp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303124,555,518 - 124,638,558 (-)NCBI
SpeTri2.0NW_00493646916,979,220 - 17,062,198 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1568,660,849 - 68,743,818 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11568,661,764 - 68,742,961 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21576,153,602 - 76,234,812 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap15q21NCBI
DPP4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11047,396,605 - 47,481,478 (-)NCBI
ChlSab1.1 Ensembl1047,394,093 - 47,480,893 (-)Ensembl
Dpp4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247323,460,529 - 3,535,252 (+)NCBI

Position Markers
DPP4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2346,964,111 - 46,964,311 (+)MAPPER
Rnor_6.0348,292,924 - 48,293,123NCBIRnor6.0
Rnor_5.0354,959,015 - 54,959,214UniSTSRnor5.0
RGSC_v3.4344,281,124 - 44,281,323UniSTSRGSC3.4
Celera346,605,205 - 46,605,404UniSTS
Cytogenetic Map3q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3195176874Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3263142148562146Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)3600074851687917Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)3600074851687917Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31009408193415837Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31011931879772001Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31409041148562146Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31409041148562146Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31409041148562146Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31409041148562146Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31409041148562146Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31409041148562146Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31409041148562146Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31802366463023664Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat
631685Bp118Blood pressure QTL 1183.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)32465522569655225Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)32813672851687917Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)32813672851687917Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)32813672851687917Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)32813672851687917Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)32813672851687917Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32932171474321714Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32968273274682732Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32968273274682732Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32968273274682732Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32968273274682732Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32968273274682732Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32990825574908255Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32990825574908255Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)330114912123700444Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)330846101172879276Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33110358972989078Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33110358972989078Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33110358972989078Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33110358972989078Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33110358972989078Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33110358972989078Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33213099777130997Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33213099777130997Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33347735462922975Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33347735481136227Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333477354108914061Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)334394121103141944Rat
10450813Scl74Serum cholesterol level QTL 745.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33924839152182792Rat
10450852Stl33Serum triglyceride level QTL 333.40.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)33924839152182792Rat
10450816Scl75Serum cholesterol level QTL 754.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33924839152182792Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)339248391140271184Rat
4889975Bmd81Bone mineral density QTL 814.3tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)33977324751687917Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)34042292185422921Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)34052359354745780Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)34052359364880586Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)34052359392654473Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)34052359392654473Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)343295930108914061Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)343295930163640485Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)343295930163640485Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34540605894467785Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)345406058127023997Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)345406058177699992Rat


Genetic Models
This gene Dpp4 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:33
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000040482
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 39 29 19 29 31 14 11
Low 1 41 18 12 12 8 10 64 4 25 8
Below cutoff 1 10 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000040482   ⟹   ENSRNOP00000045536
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl348,293,617 - 48,372,583 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077788   ⟹   ENSRNOP00000072092
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl348,292,739 - 48,372,609 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085426   ⟹   ENSRNOP00000068881
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl348,291,055 - 48,372,672 (-)Ensembl
RefSeq Acc Id: NM_012789   ⟹   NP_036921
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,962,243 - 47,043,870 (-)NCBI
Rnor_6.0348,291,055 - 48,372,672 (-)NCBI
Rnor_5.0354,957,146 - 55,038,628 (-)NCBI
RGSC_v3.4344,279,255 - 44,360,283 (-)RGD
Celera346,603,336 - 46,685,074 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_036921 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41096 (Get FASTA)   NCBI Sequence Viewer  
  AAA41272 (Get FASTA)   NCBI Sequence Viewer  
  EDL79005 (Get FASTA)   NCBI Sequence Viewer  
  EDL79006 (Get FASTA)   NCBI Sequence Viewer  
  P14740 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_036921   ⟸   NM_012789
- Sequence:
RefSeq Acc Id: ENSRNOP00000068881   ⟸   ENSRNOT00000085426
RefSeq Acc Id: ENSRNOP00000072092   ⟸   ENSRNOT00000077788
RefSeq Acc Id: ENSRNOP00000045536   ⟸   ENSRNOT00000040482
Protein Domains
DPPIV_N   DPPIV_rep   Peptidase_S9

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692100
Promoter ID:EPDNEW_R2623
Type:initiation region
Name:Dpp4_1
Description:dipeptidylpeptidase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0348,372,675 - 48,372,735EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2515 AgrOrtholog
Ensembl Genes ENSRNOG00000030763 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000045536 UniProtKB/TrEMBL
  ENSRNOP00000068881 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072092 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040482 UniProtKB/TrEMBL
  ENSRNOT00000077788 UniProtKB/TrEMBL
  ENSRNOT00000085426 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.140.10.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DPPIV_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_S9_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9B_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9B_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25253 UniProtKB/Swiss-Prot
NCBI Gene 25253 ENTREZGENE
Pfam DPPIV_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DPPIV_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dpp4 PhenoGen
PROSITE PRO_ENDOPEP_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC229485
UniProt A0A0G2JTX5_RAT UniProtKB/TrEMBL
  A0A0G2K238_RAT UniProtKB/TrEMBL
  DPP4_RAT UniProtKB/Swiss-Prot
  F1M7X5_RAT UniProtKB/TrEMBL
  P14740 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Dpp4  Dipeptidyl peptidase 4      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_other genetic deficiency of dipeptidyl peptidase IV is noted in the F344/DuCrj strain 728469