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Gene: Dpp4 (dipeptidylpeptidase 4) Mus musculus
Symbol: Dpp4
Name: dipeptidylpeptidase 4
Description: Predicted to have several functions, including chemorepellent activity; peptidase activity, acting on L-amino acid peptides; and protein homodimerization activity. Involved in behavioral fear response; locomotory exploration behavior; and psychomotor behavior. Localizes to intercellular canaliculus. Is expressed in several structures, including inner ear; intraembryonic coelom; liver; lung; and primitive heart tube. Used to study Middle East respiratory syndrome. Human ortholog(s) of this gene implicated in Middle East respiratory syndrome and type 2 diabetes mellitus. Orthologous to human DPP4 (dipeptidyl peptidase 4); INTERACTS WITH (S)-nicotine; 1,1-dichloroethene; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cd26; dipeptidyl peptidase 4; dipeptidyl peptidase IV; DPP IV; Dpp-4; T-cell activation antigen CD26; THAM; thymocyte-activating molecule
Homo sapiens (human) : DPP4 (dipeptidyl peptidase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dpp4 (dipeptidylpeptidase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dpp4 (dipeptidyl peptidase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : DPP4 (dipeptidyl peptidase 4)
Canis lupus familiaris (dog) : DPP4 (dipeptidyl peptidase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpp4 (dipeptidyl peptidase 4)
Sus scrofa (pig) : DPP4 (dipeptidyl peptidase 4)
Chlorocebus sabaeus (African green monkey) : DPP4 (dipeptidyl peptidase 4)
Heterocephalus glaber (naked mole-rat) : Dpp4 (dipeptidyl peptidase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl262,330,073 - 62,412,231 (-)EnsemblGRCm38mm10GRCm38
GRCm38262,330,073 - 62,412,315 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37262,168,130 - 62,250,288 (-)NCBIGRCm37mm9NCBIm37
MGSCv36262,132,579 - 62,212,921 (-)NCBImm8
Celera264,022,145 - 64,102,355 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map235.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dpp4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10481
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.