Scort3 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Scort3 (Serum corticosterone level QTL 3) Rattus norvegicus

Symbol: Scort3
Name: Serum corticosterone level QTL 3
RGD ID: 9590136
Previously known as: plasma corticosterone at basal level; plasma cort at basal level
Trait: blood corticosterone amount   (VT:0005345)    
Measurement Type: plasma corticosterone level   (CMO:0001173)    
LOD Score: 23.37
P Value: 0.001
Variance: 15.4
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8348,657,744 - 93,657,744RGD_MAPPER_PIPELINE
mRatBN7.2328,249,687 - 73,249,687RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0329,682,732 - 74,682,732RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0336,313,853 - 81,313,853RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4325,533,304 - 70,533,304RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort3Ratlipid metabolism disorder  IAGP 8694157 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort3Ratincreased circulating corticosterone level  IDA 8694157 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort3Ratplasma corticosterone level  IDA 8694157 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort3Ratcontrol condition  IDA 8694157 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort3Ratradioimmunoassay  IDA 8694157 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort3RatF344/IcoCrlf  IEA 8694157 RGD 
Scort3RatLOU/NimrOlaHsd  IEA 8694157 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort3Ratblood corticosterone amount  IDA 8694157 RGD 


#
Reference Title
Reference Citation
1. Quantitative Trait Loci Influencing Abdominal Fat Deposition and Functional Variability of the HPA Axis in the Rat. Marissal-Arvy N, etal., Horm Metab Res. 2014 Jul 8.


1 to 20 of 598 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1359304Arhgap15Rho GTPase activating protein 1532798936828592722Rat
41176684LOC120102081small nucleolar RNA SNORA4032830634528306467Rat
41066404LOC120102110U2 spliceosomal RNA32855995628560093Rat
1563393Gtdc1glycosyltransferase-like domain containing 132876664029161668Rat
41007407Rnu2-18RNA, U2 small nuclear 1832881327728813416Rat
11498418LOC108350367uncharacterized LOC10835036732887037328882513Rat
1307272Zeb2zinc finger E-box binding homeobox 232921458129344890Rat
9273023Zeb2-as1ZEB2 antisense RNA 132934307829345943Rat
7498952LOC102548671uncharacterized LOC10254867132943454929491656Rat
9075793LOC103690391uncharacterized LOC10369039132957970029583753Rat
11373432LOC108350369uncharacterized LOC10835036932962628029676672Rat
41353600LOC120101545uncharacterized LOC12010154532974202229786773Rat
7622113LOC102548934uncharacterized LOC10254893432999381829998722Rat
41041303LOC120102076small nucleolar RNA SNORA1733052038230520498Rat
2322483Traf7-ps2TNF receptor associated factor 7, pseudogene 233076880130770318Rat
41087157LOC120102072small nucleolar RNA SNORA1733081550330815603Rat
2323086Ddx18-ps2DEAD-box helicase 18, pseudogene 233120713731210520Rat
11429489LOC108350370uncharacterized LOC10835037033121664431228107Rat
9265290Elobl8elongin B like 833125526531255970Rat
41126518LOC120101546uncharacterized LOC12010154633134491731365067Rat

1 to 20 of 598 rows
1 to 20 of 579 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10275D3Wox1519536943021969430414Ratregion
10625D3Mgh2012434711353147113655Ratregion
10678D3Mgh2118234187457841874764Ratregion
11260D3Mit820735030267950302886Ratregion
11261D3Wox912735043691350437042Ratregion
11262D3Wox1012635043691350437041Ratregion
11263D3Wox1426635043678550437053Ratregion
11264D3Arb724835043691250437162Ratregion
33862D3Mit924533035677330357018Ratregion
34146D3Mgh69935318459353184692Ratregion
34336D3Mgh714333945463739454780Ratregion
36047D3Rat4614733684746636847613Ratregion
36261D3Rat3216836822606368226231Ratregion
36311D3Rat3917335853954358539716Ratregion
37282D3Rat10317234539071445390751Ratregion
37282D3Rat10317234539071445390886Ratregion
37394D3Rat12322734480510444805331Ratregion
37510D3Rat10022533819223338192458Ratregion
37538D3Rat11919735522363155223816Ratregion
37588D3Rat18917933871036538710544Ratregion
1 to 20 of 579 rows

Peak: (D3Rat66)
Rat AssemblyChrPosition (strand)Source
GRCr8371,157,684 - 71,157,804 (+)Marker Load Pipeline
mRatBN7.2350,749,627 - 50,749,747 (+)MAPPER
Rnor_6.0352,182,673 - 52,182,792NCBI
Rnor_5.0358,813,794 - 58,813,913UniSTS
RGSC_v3.4348,033,244 - 48,033,364RGD
RGSC_v3.4348,033,245 - 48,033,364UniSTS
RGSC_v3.1347,929,617 - 47,929,736RGD
Celera350,339,425 - 50,339,544UniSTS
RH 3.4 Map3609.5UniSTS
RH 3.4 Map3609.5RGD
RH 2.0 Map3416.3RGD
FHH x ACI Map336.06RGD
Cytogenetic Map3q21UniSTS


1 to 10 of 97 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)32749462144188411Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
10450816Scl75Serum cholesterol level QTL 754.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33819223350749747Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat

1 to 10 of 97 rows


Note Type Note Reference
qtl_general confidence interval 48.9-77.1 Mb 8694157
qtl_general number of animals used: 93 F2 males and 94 F2 females 8694157
qtl_general measurement method: blood samples were taken in the morning and collected on EDTA, centrifuged at 4000g for 10 min to extract the plasma, plasma corticosterone was measured with an in-house RIA kit using an anti-Cort antibody 8694157
qtl_general software package used: MultiQTL software 8694157
qtl_general an additional peak at D3Mit12 with confidence interval 99.7-121.8 Mb was observed 8694157