Arl5a (ADP-ribosylation factor like GTPase 5A)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| FTP Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Arl5a (ADP-ribosylation factor like GTPase 5A) Rattus norvegicus

Analyze

Symbol:

Arl5a

Name:

ADP-ribosylation factor like GTPase 5A

RGD ID:

621327

Description:

Predicted to have GTP binding activity. Predicted to be involved in intracellular protein transport; protein localization to Golgi membrane; and vesicle-mediated transport. Predicted to localize to trans-Golgi network. Orthologous to human ARL5A (ADP ribosylation factor like GTPase 5A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3H-1,2-dithiole-3-thione.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

ADP-ribosylation factor-like 5; ADP-ribosylation factor-like 5A; ADP-ribosylation factor-like protein 5A; Arl5

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ARL5A (ADP ribosylation factor like GTPase 5A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Arl5a (ADP-ribosylation factor-like 5A)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Arl5a (ADP ribosylation factor like GTPase 5A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ARL5A (ADP ribosylation factor like GTPase 5A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ARL5A (ADP ribosylation factor like GTPase 5A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Arl5a (ADP ribosylation factor like GTPase 5A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ARL5A (ADP ribosylation factor like GTPase 5A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	ARL5A (ADP ribosylation factor like GTPase 5A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Arl5a (ADP ribosylation factor like GTPase 5A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ARL5B (ADP ribosylation factor like GTPase 5B)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	ARL5A (ADP ribosylation factor like GTPase 5A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Arl5a (ADP-ribosylation factor-like 5A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	arl5a (ADP-ribosylation factor-like 5A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	Arl5	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	arl-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	3	37,922,544 - 37,947,434 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	37,924,793 - 37,947,283 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	43,026,193 - 43,047,118 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	33,905,755 - 33,926,681 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	33,800,410 - 33,822,902 (-)	NCBI
Celera	3	35,024,333 - 35,045,257 (-)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

nemaline myopathy 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (EXP)

3H-1,2-dithiole-3-thione (EXP)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

calciol (ISO)

chlorpyrifos (EXP)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cyproconazole (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

haloperidol (EXP)

hydrogen peroxide (ISO)

isobutanol (ISO)

lead(0) (ISO)

lead(2+) (ISO)

methyl methanesulfonate (ISO)

miconazole (ISO)

N-nitrosodiethylamine (ISO)

nefazodone (EXP)

ochratoxin A (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

propiconazole (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sodium arsenate (ISO)

tetrachloromethane (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular protein transport (IBA)

protein localization to Golgi membrane (IBA,ISO)

vesicle-mediated transport (IBA)

Cellular Component

trans-Golgi network (IBA)

Molecular Function

GTP binding (IBA,TAS)

References

References - curated


1.	Breiner M, etal., Biochim Biophys Acta 1996 Jul 31;1308(1):1-6.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	MGD data from the GO Consortium
4.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	RGD automated data pipeline
6.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:25795912

Genomics

Comparative Map Data

Arl5a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	3	37,922,544 - 37,947,434 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	37,924,793 - 37,947,283 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	43,026,193 - 43,047,118 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	33,905,755 - 33,926,681 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	33,800,410 - 33,822,902 (-)	NCBI
Celera	3	35,024,333 - 35,045,257 (-)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

ARL5A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	151,788,984 - 151,828,492 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	151,798,797 - 151,828,421 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	152,657,480 - 152,685,009 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	152,365,726 - 152,393,255 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	152,484,611 - 152,510,503	NCBI
Celera	2	146,272,160 - 146,299,690 (-)	NCBI
Cytogenetic Map	2	q23.3	NCBI
HuRef	2	144,543,720 - 144,571,242 (-)	NCBI		HuRef
CHM1_1	2	152,663,024 - 152,690,587 (-)	NCBI		CHM1_1

Arl5a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	52,287,961 - 52,314,886 (-)	NCBI	GRCm39		mm39
GRCm38	2	52,397,949 - 52,424,874 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	52,397,951 - 52,424,901 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	52,253,471 - 52,280,394 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	52,219,960 - 52,246,883 (-)	NCBI			mm8
Celera	2	54,127,859 - 54,154,901 (-)	NCBI		Celera
Cytogenetic Map	2	C1.1	NCBI

Arl5a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955440	17,329,450 - 17,361,646 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955440	17,329,450 - 17,341,836 (-)	NCBI	ChiLan1.0	ChiLan1.0

ARL5A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2B	156,337,533 - 156,368,974 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	156,344,048 - 156,368,974 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2B	39,092,366 - 39,133,505 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

ARL5A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	19	52,947,922 - 52,973,406 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	19	52,949,533 - 52,973,408 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Arl5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936469	25,750,247 - 25,773,693 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARL5A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	467,995 - 498,887 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	467,925 - 498,889 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ARL5A
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	37,206,303 - 37,236,255 (-)	NCBI

Arl5a
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624866	5,291,025 - 5,319,841 (+)	NCBI

Position Markers

RH141305

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	37,926,562 - 37,926,762	NCBI	Rnor6.0
Rnor_5.0	3	43,026,246 - 43,026,446	UniSTS	Rnor5.0
RGSC_v3.4	3	33,905,808 - 33,906,008	UniSTS	RGSC3.4
Celera	3	35,024,386 - 35,024,586	UniSTS
Cytogenetic Map	3	q12	UniSTS
RH 3.4 Map	3	446.82	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	39773425	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	95176874	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	2631421	48562146	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	6000748	51687917	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	3	6000748	51687917	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10094081	93415837	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	10119318	79772001	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	13126914	41510346	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14090411	48562146	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	14090411	48562146	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	14090411	48562146	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	14090411	48562146	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	14090411	48562146	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	14090411	48562146	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	14090411	48562146	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	18023664	63023664	Rat
10450794	Scl69	Serum cholesterol level QTL 69	6.3	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	21223803	66223803	Rat
10450804	Scl70	Serum cholesterol level QTL 70	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	21223803	66223803	Rat
631685	Bp118	Blood pressure QTL 118	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	24655225	69655225	Rat
1298073	Cm13	Cardiac mass QTL 13	2.5		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	25633366	39248391	Rat
631832	Sach1	Saccharin preference QTL 1	2.7	0.02	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	3	28136728	45772990	Rat
2313049	Bss72	Bone structure and strength QTL 72	2.6	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	3	28136728	51687917	Rat
2313076	Bss74	Bone structure and strength QTL 74	2	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	3	28136728	51687917	Rat
2313079	Bss73	Bone structure and strength QTL 73	1.5		tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	3	28136728	51687917	Rat
2313093	Bmd77	Bone mineral density QTL 77	2.2	0.0001	tibia mineral mass (VT:1000283)	cortical volumetric bone mineral density (CMO:0001730)	3	28136728	51687917	Rat
2313101	Bmd76	Bone mineral density QTL 76	3.6	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	3	28136728	51687917	Rat
2302055	Pia30	Pristane induced arthritis QTL 30	3.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	3	29321714	74321714	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	29682732	74682732	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	29682732	74682732	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	29682732	74682732	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	29682732	74682732	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	29682732	74682732	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	29908255	74908255	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	29908255	74908255	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	30114912	123700444	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	30846101	172879276	Rat
2301400	Cm68	Cardiac mass QTL 68		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	31103589	72989078	Rat
11565451	Bw177	Body weight QTL 177		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	3	31103589	72989078	Rat
11565452	Kidm57	Kidney mass QTL 57		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	31103589	72989078	Rat
12879866	Cm94	Cardiac mass QTL 94		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	31103589	72989078	Rat
12879867	Cm95	Cardiac mass QTL 95		0.047	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	31103589	72989078	Rat
12879868	Am6	Aortic mass QTL 6		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	31103589	72989078	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	32130997	77130997	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	32130997	77130997	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	33477354	62922975	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	33477354	81136227	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33477354	108914061	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	34394121	103141944	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	485
Count of miRNA genes:	211
Interacting mature miRNAs:	267
Transcripts:	ENSRNOT00000009181
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	42	57	41	19	41	8	10	74	35	34	11	8
Low		1						1			7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761696	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07052125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01021824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X78604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000009181 ⟹ ENSRNOP00000009181

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	37,924,793 - 37,947,283 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000076134

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	37,926,794 - 37,946,999 (-)	Ensembl

RefSeq Acc Id:

NM_053979 ⟹ NP_446431

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	37,926,509 - 37,947,434 (-)	NCBI
Rnor_5.0	3	43,026,193 - 43,047,118 (-)	NCBI
RGSC_v3.4	3	33,905,755 - 33,926,681 (-)	RGD
Celera	3	35,024,333 - 35,045,257 (-)	RGD

Sequence:

show sequence

CCGCGAGCCAGGCGAGCGCCGCGGCGGTAGCGGCGGGGCCTCGCGCGTGGCTAGGTGGCCTGGG
CTGCGGCCTCCCCGCGGGTCCCTGGAAGCGGGCGCGCGGCCGGCGCGGGAGCAGAGGCGGAGGC
CCCGGCGCGTCCTTCTGCCCCGCAGCCTGAGCCCGGGCGGCTGGAGGGCTCCGCTGCCCGAGGA
TGGGAATTCTCTTCACCCGGATCTGGAGACTGTTCAATCACCAGGAGCACAAAGTTATTATTGT
TGGGCTGGACAATGCCGGGAAGACTACCATCCTTTACCAGTTTTCCATGAATGAAGTTGTACAT
ACATCTCCTACAATAGGAAGCAATGTGGAAGAGATTGTGGTTAATAATACACGTTTCCTGATGT
GGGATATTGGTGGCCAAGAATCCCTTCGTTCTTCCTGGAACACTTATTATACTAACACAGAGTT
TGTAATAGTTGTGGTGGACAGCACAGACAGAGAAAGAATTTCTGTAACTAGAGAAGAGCTCTAC
AAAATGCTAGCCCACGAGGACCTAAGGAAAGCTGGGTTGCTGATTTTTGCTAATAAACAAGATG
TTAAAGAATGCATGACAGTAGCAGAAATCTCCCAGTTTTTGAAGCTCACTTCTATAAAAGACCA
CCAATGGCATATCCAAGCATGCTGTGCTCTCACTGGCGAGGGGTTATGCCAAGGACTTGAATGG
ATGATGTCACGGCTGAAGATCAGATGATCTCTTCTGACCCCTTCTCATGGACTCTGTATAAACA
AAGTGCTGGACTTTATCTGAAAGCTGCAAAAAATGGTTTAGATATATTTATAATAAACTGACTT
AAGAGTTTTCTACAAGAAGAAAATTAAGACCATTTATTTGAAAACAGATGAAATGTCACCACCT
CGTTTGCTCTCTCATTCCTTCCAAACCTGTGACTGGTATTTTCTCATGATGAATCCTCTCCGGA
CATGGGAGAGTTCTAATGAATACAAGGGAGAGGAAGACATTTGAACTTGGAGCTTTATTTCCTC
GACGAGCCCACCCTGCCCCAAGTGAATGTTCCCTTTTCATTACATTGAATCAAATACGGATCAG
CACGGATACTGTTTCCAGTTTTTAAAAATGTAATAATATTATGGAAAGTATTTTACTTAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008761696 ⟹ XP_008759918

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	37,922,544 - 37,947,172 (-)	NCBI

Sequence:

show sequence

CCCGGCCCTTGTCGGGCGGAGGGGGTCGCCTTTGTCTCTCGGGAGCTGGGGAGAGCTTCCTCCC
GCCATACACCCATTGCTCCGATTTGATCGCGAGCGCGAAAGGTGTCCTGCTCCACGCCGGGGGC
CCAACGCGCGGCCTGGCCTGCCTCCATCCGCGTCGCCGGCCGGCAGTTGTGTTTGGGCCGCACT
GACAACAGCTGGGGTTCTAGGGTGAAGACCGAGGGCCCTGGCCCTAGAGGCGCCACCGAGCCCA
CAGTTTGCAGAATGCGGAAAACTGGAACTAGTGCTGGACTCGTCTGAGCACAAAGTTATTATTG
TTGGGCTGGACAATGCCGGGAAGACTACCATCCTTTACCAGTTTTCCATGAATGAAGTTGTACA
TACATCTCCTACAATAGGAAGCAATGTGGAAGAGATTGTGGTTAATAATACACGTTTCCTGATG
TGGGATATTGGTGGCCAAGAATCCCTTCGTTCTTCCTGGAACACTTATTATACTAACACAGAGT
TTGTAATAGTTGTGGTGGACAGCACAGACAGAGAAAGAATTTCTGTAACTAGAGAAGAGCTCTA
CAAAATGCTAGCCCACGAGGACCTAAGGAAAGCTGGGTTGCTGATTTTTGCTAATAAACAAGAT
GTTAAAGAATGCATGACAGTAGCAGAAATCTCCCAGTTTTTGAAGCTCACTTCTATAAAAGACC
ACCAATGGCATATCCAAGCATGCTGTGCTCTCACTGGCGAGGGGTTATGCCAAGGACTTGAATG
GATGATGTCACGGCTGAAGATCAGATGATCTCTTCTGACCCCTTCTCATGGACTCTGTATAAAC
AAAGTGCTGGACTTTATCTGAAAGCTGCAAAAAATGGTTTAGATATATTTATAATAAACTGACT
TAAGAGTTTTCTACAAGAAGAAAATTAAGACCATTTATTTGAAAACAGATGAAATGTCACCACC
TCGTTTGCTCTCTCATTCCTTCCAAACCTGTGACTGGTATTTTCTCATGATGAATCCTCTCCGG
ACATGGGAGAGTTCTAATGAATACAAGGGAGAGGAAGACATTTGAACTTGGAGCTTTATTTCCT
CGACGAGCCCACCCTGCCCCAAGTGAATGTTCCCTTTTCATTACATTGAATCAAATACGGATCA
GCACGGATACTGTTTCCAGTTTTTAAAAATGTAATAATATTATGGAAAGTATTTTACTTAAAGT
TGAATATGTATTGTGTATATACCTCAAGTTCAGGTTAATGGCTTTGATTTATTTGTGTTCTAAA
GGAAAGCAAATAACACAAGTTAATGACGTTATTTTCCTGATGTCACTGAGTACCATCTTGGTGT
TAATTGTCACTGTTTAGTTTACCCTCTGTTCTCTGTATTGTTCTAACAAGCCAACCCCAGCCCA
GAATCGGTAAGCTGCTCCTTAAAAATGAAACGGGAGAAAGCTTGACATTGTGTACCTATTTTTG
TTGCTCAGTCATACAGATGGAAATCCATAACGCAAGTGGGTAGAGTCTGCTGGACTCCTGGCCT
GGTGTGGCCGGGCAGAATTACTCGAGAAGCAGTTGTCAGACTTTCCCTTCTGCTGGTCCTAATT
CAGCCAATTCAGCTACTAATCGGTCATTCATAAATTGTGATTAAAATGATCAGGTAATTTTTAA
TTGAAAATCATGTTGTGAAATATATCTACCCAAAGAGGTAACATCCTATAAATAGTAATAATTA
ATTTAGCTGCAGCCTTTTCAGGTATTAAATTATATGACAAACAGTTAAAATGAATTTAAGAGTA
AACATAAGGCATAGTTTTCAGTGAACATTAATAATTTCTCAATTTGCAGATTAGCATCTGCAAA
GGTATCTTCTTCCATTGCATAAAATGCCTTGTTTAATAGTTAACTAATCAAATATTCTGAATGA
CTTCAAAAATTTGATTGAAAATTTGAGATATCACATTATTTGTACTAGGATTTGACCTAAAACA
CCTTTTATATTTGTTAACCTTTCTTAAATTTAGTTAAAATTTGAAGTATTTCTGTCGTAATTAT
AAACAAAATTATTTTGTGTTTTAACATATTCTTGGTGACTCTTTATACTTTTTGTGCCCTGAAA
ATTTGAAGGTTACTCCAAACTGTCAAGATTTAGGATATTCAAGAAAAGATTTAACTAGTTTTAG
TGTCAGACTTTAAAATTTCCTAAGGAATTTGGTAAGAAATAGAAGTCCACTCTATAAGCATTGA
GGAAACTTTGAAAAACCTTTAAGTAAATGTAAGACTCTTAATGACTAAACCCATCGGAGTGGAT
GAGTGTTCCCCTGGAGGCTTGTGTTTGAGACCTGTGCTGTAAGCCTCCCACTTGACCTTCAGCG
TAATGTTTCCCACCTGCTCAGAGTGTCAGCACTCGTCACTAGGCTTTCCAGGGCTAAGTCCTTC
CTGTTCACATGTTCTCACACTTTTTCAAATCATGAGGCTTTCTCCTGTATAGTAAAAATCCCCT
TAAAGACTCAAATCTACGTCGTAGTTTTGTCAGAGACCAATAGTCCATCGAGCCCCCACCTACC
CCAGATCTGCAGCTTCTTAGCTTTTATCTGAATAGTCCTTGCACAGTTGCTTGCCTCTCTGTCA
CATCAGTTCAGCACATAGCAGCACATCCTGGTGTTGCCGAGGTATTGGCTAGAATTTATTCTTA
ATTAGATGTTTAAAGCATTTACTCCACTGTTAAAGTTGTCTTAGTGTAGTCAGGTATTGACATG
ACATAAGAAAGCATGAAACTACCACATTTACAAAATATGAGGGATTTGGGGTTTGGTTTTTTTT
GTTTGTTTGGTTGGTTTTTTTTTTTTTTGGTTTTTAACTATTTTAGACTCAAATAATATCATAC
CTGTGTACTTGTACATAAAAACAAAATTATTACTGAGTAAAAAGATTAATATATGAACTATCAC
AGCTGTCGTTAACAGTATTAATGAGGTCTGAATCCGGAGGGTCCCCTGATTACCATGCTGACAG
TTCACATGTCATAGGGCAGAACTCAGCAAGTCCTGTGGTTTCAGGTGTTAATAAGTAAACGTCT
CATCCAACCTCACTGTGCTCAGCTTTGAAAAGAACAAAGATTATACCTCTGTACATGTGGGTAG
ATTTAAAGTGTCCTGTTTTGATACTAATTTTGAAAGTTGTTTATCTTCTCTTGATATCTTGGTA
AAACTGGCCGTAAGAGAAACCATTTGAATATATTTGATTTTGTCATAGCATTTATAAAATGTAT
GTTTCCCATTATATTGAGAGTTTTATTTTAAAAATCCCCTTATGTTTCTAGCACACCTTGGCCA
TCACAGTAGACAAAGAATTCAGAGAAGGCGAGTGGGTTAGGCTGGGGGAATGAGTATTCATTTT
TTTCTCCTGACATTGTCTCTTAAGAAGAAAGTGCTGGCTGGCATCTTTAATGCGGGTTGTGAGC
CTAATTACATAAGCATGAGCCAGAAGGGAGAGGACTTTGCTCCCTGGCCTTTAAGAAGTGCCTC
GTAGGTAATCATGGAAGTCACAGGTAAGTGCAGGAGCTTGACCGTAGGCAAGAGGTCTCTAAGG
TGTTCTTTTCCTTTGTCTGAGTGTATAGTATTACGATGCCTAGAAGGGGGGCGCTGTTGGCCCT
CCCTTACAGGCACTTTCTATTTCTTGCTGTAACTACAGCAATCACATACAGTACAGACAACCTC
AATCTGTTTATATTAGTGTGTAAATAGAAAAACTGTAAACAGCTGTCTAGTCTTCTCCGCAGGC
ATTTTGGGAATGCTTCTATACTCTGTTCTACTTTGTTAATGGGGAATAACAGCACATCCTAGAT
CACCTGTGAACTTTGGGGTCTTCTGATTGCCCTTGGTATCCTGATATTCTCATTTCCAAGATGA
GGTAGAGACAGGGTTTCCTTGCATAACAGATTTGAGCACCTGCGTTCTGCAAACACAATCTCAA
GAGCAGTTCCATAGCTCAGCTAGCCATTGCTGCCCCGATGCTTGCCCTCCACCAACGGAGGTCG
CCTCTGCAGAGTCTACACTTTGCCCATAACCCTCATTCCCCAGACCTAGGCTTTGAGTAACTGC
TCTGATTCTGTCCGCCCACCCACCAGTGACTCACCACTCTGCACACTCCCATCTTCAGAGATGC
GGAGTCTCTCAGGACAGCAGCTTCAGATCATGGTATACAGATACCAGTAGAAGAATCGGACATT
GTACTGCCCTTAGCACCTTAACTCTACTTAACAATCACAACTAGATTCAGAAATACAAGAAAGA
TATATAGACTATGTCAGGTCCTTAAGTTAGGAATTAGGACCAAAGGCTATTAACTTACATTCAC
ATTATCCTCATGTAGCCAAGAGTGGTGATGTTTTGGAGAATACCAGTCCAGCCAGGCTAACATG
AAGATGACAGAACTGTGGTGTTGAGCCTGAAGACATCCTAAAATGGTTTCCCTTGCTCCATTTT
TCTTCACATTTGCTTACATAGCAAAGACCAGCATTAAATGTCTAAAGGAATTTTTAATTTGAGA
GCTAGTATTACAAAATAAACCTGCTAAAACGGGCTTTAAAAGACAGCAAAATAAGCCATATGTA
GTGGTGTTAAAACTAATCCCAGCACTCAGGAAGCTGAGACAGGAGACTCGCTGGGCATACAAGG
TCAACCTGGGATAAATAGTATCAGCCACCATGACTACAAAGGGAAAGACTGTCACAAAGGAAAA
GAAGAAGGAAGGAAAAGCCAGCAGTCAACCATCATGTGTTTCTGTAGATTCAGATGTGATAGAT
TCAGGATGCTTCTTATAAAACATCTGTGTCATGTTCCTTAAAGCAGGTGCGCTCCTTTAAGACC
ATGACAGTAGGCTAAGGGAAAGAGTGAAATCCAACACTCAAAGTGAGAGCTTATATTTAACCCT
AAAGTGGATTGAAATCGGGGAGAGATGTAATACAGGATACAGGTGGGCTAATTATGCAATATTT
CTTCTTTCTAATTCTCTAACTCTGTACTGTTCCTAAAAATGGATGAGTGAGTCTCTGTGGTGTT
GCCTGCTCAATGTGCATATCCTTGGTAGACATTTCTCATAGTGTGTACTTAAAAAGTGCCTGAC
ATTGATTTGTGTTGATTTCTAAGTCCATGTAATAAACGATACATGTTTTCTATGATAGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_446431	(Get FASTA)	NCBI Sequence Viewer
	XP_008759918	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97294	(Get FASTA)	NCBI Sequence Viewer
	CAA55338	(Get FASTA)	NCBI Sequence Viewer
	EDM00435	(Get FASTA)	NCBI Sequence Viewer
	EDM00436	(Get FASTA)	NCBI Sequence Viewer
	EDM00437	(Get FASTA)	NCBI Sequence Viewer
	P51646	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_446431 ⟸ NM_053979
- UniProtKB:	P51646 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVVNNTRFLM WDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQD VKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR hide sequence

RefSeq Acc Id:	XP_008759918 ⟸ XM_008761696
- Peptide Label:	isoform X1
- Sequence:	show sequence MNEVVHTSPTIGSNVEEIVVNNTRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISV TREELYKMLAHEDLRKAGLLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGL CQGLEWMMSRLKIR hide sequence

RefSeq Acc Id:

ENSRNOP00000009181 ⟸ ENSRNOT00000009181

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621327	AgrOrtholog
Ensembl Genes	ENSRNOG00000006839	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000009181	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000009181	ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7458249	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot
	Small_GTPase_ARF/SAR	UniProtKB/Swiss-Prot
KEGG Report	rno:117050	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114279	IMAGE-MGC_LOAD
NCBI Gene	117050	ENTREZGENE
Pfam	Arf	UniProtKB/Swiss-Prot
PhenoGen	Arl5a	PhenoGen
PRINTS	SAR1GTPBP	UniProtKB/Swiss-Prot
PROSITE	ARF	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
TIGRFAMs	small_GTP	UniProtKB/Swiss-Prot
UniGene	Rn.2803	ENTREZGENE
UniProt	ARL5A_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q4V8N2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-19	Arl5a	ADP-ribosylation factor like GTPase 5A	Arl5a	ADP-ribosylation factor-like 5A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Arl5a	ADP-ribosylation factor-like 5A	Arl5	ADP-ribosylation factor-like 5	Symbol and Name updated	1299863	APPROVED
2005-01-20	Arl5	ADP-ribosylation factor-like 5			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Arl5	ADP-ribosylation factor-like 5			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	ubiquitously expressed; enriched in brain, intestine, and thymus	724591

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar