Tank (TRAF family member-associated NFKB activator) - Rat Genome Database
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Gene: Tank (TRAF family member-associated NFKB activator) Rattus norvegicus
Analyze
Symbol: Tank
Name: TRAF family member-associated NFKB activator
RGD ID: 628859
Description: Predicted to contribute to thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in several processes, including I-kappaB kinase/NF-kappaB signaling; cellular response to cytokine stimulus; and positive regulation of proteolysis. Predicted to localize to cytosol and protein-containing complex. Orthologous to human TANK (TRAF family member associated NFKB activator); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 17beta-estradiol; 3-methylcholanthrene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: TRAF family member-associated Nf-kappa B activator; TRAF family member-associated NF-kappa-B activator; TRAF interacting protein TANK
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2346,114,253 - 46,190,270 (+)NCBI
Rnor_6.0 Ensembl347,439,076 - 47,515,700 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0347,439,007 - 47,515,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0354,111,767 - 54,188,472 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4343,396,247 - 43,475,491 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1343,329,797 - 43,371,197 (+)NCBI
Celera345,783,047 - 45,858,966 (+)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8710854   PMID:11279055   PMID:12477932   PMID:15882800   PMID:25861989  


Genomics

Comparative Map Data
Tank
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2346,114,253 - 46,190,270 (+)NCBI
Rnor_6.0 Ensembl347,439,076 - 47,515,700 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0347,439,007 - 47,515,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0354,111,767 - 54,188,472 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4343,396,247 - 43,475,491 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1343,329,797 - 43,371,197 (+)NCBI
Celera345,783,047 - 45,858,966 (+)NCBICelera
Cytogenetic Map3q21NCBI
TANK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2161,136,908 - 161,236,230 (+)EnsemblGRCh38hg38GRCh38
GRCh382161,136,963 - 161,236,230 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372161,993,474 - 162,092,741 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh372161,993,438 - 162,092,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362161,701,712 - 161,800,928 (+)NCBINCBI36hg18NCBI36
Build 342161,818,972 - 161,886,997NCBI
Celera2155,605,253 - 155,704,471 (+)NCBI
Cytogenetic Map2q24.2NCBI
HuRef2153,878,179 - 153,977,180 (+)NCBIHuRef
CHM1_12161,999,604 - 162,098,821 (+)NCBICHM1_1
Tank
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39261,408,901 - 61,484,515 (+)NCBIGRCm39mm39
GRCm38261,578,557 - 61,654,171 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl261,578,585 - 61,654,171 (+)EnsemblGRCm38mm10GRCm38
MGSCv37261,416,643 - 61,492,228 (+)NCBIGRCm37mm9NCBIm37
MGSCv36261,379,425 - 61,454,950 (+)NCBImm8
Celera263,280,293 - 63,355,826 (+)NCBICelera
Cytogenetic Map2C1.3NCBI
Tank
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544912,470,085 - 12,561,370 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544912,470,203 - 12,561,364 (-)NCBIChiLan1.0ChiLan1.0
TANK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B165,797,247 - 165,896,438 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B165,820,833 - 165,896,438 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B48,426,036 - 48,525,265 (+)NCBIMhudiblu_PPA_v0panPan3
TANK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl366,750,265 - 6,826,486 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1366,732,507 - 6,826,762 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tank
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493646917,665,604 - 17,754,845 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TANK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11567,970,972 - 68,048,681 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21575,433,203 - 75,529,766 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TANK
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11046,527,795 - 46,632,133 (+)NCBI
ChlSab1.1 Ensembl1046,556,614 - 46,632,186 (+)Ensembl
Tank
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247324,221,294 - 4,325,199 (-)NCBI

Position Markers
D3Chm10  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0347,500,330 - 47,500,543NCBIRnor6.0
Rnor_5.0354,173,096 - 54,173,309UniSTSRnor5.0
RGSC_v3.4343,460,143 - 43,460,357RGDRGSC3.4
RGSC_v3.4343,460,144 - 43,460,357UniSTSRGSC3.4
Celera345,843,591 - 45,843,804UniSTS
Cytogenetic Map3q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3195176874Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3263142148562146Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)3600074851687917Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)3600074851687917Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31009408193415837Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31011931879772001Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31409041148562146Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31409041148562146Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31409041148562146Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31409041148562146Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31409041148562146Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31409041148562146Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31409041148562146Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31802366463023664Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat
631685Bp118Blood pressure QTL 1183.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)32465522569655225Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)32813672851687917Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)32813672851687917Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)32813672851687917Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)32813672851687917Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)32813672851687917Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32932171474321714Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32968273274682732Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32968273274682732Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32968273274682732Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32968273274682732Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32968273274682732Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32990825574908255Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32990825574908255Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)330114912123700444Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)330846101172879276Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33110358972989078Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33110358972989078Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33110358972989078Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33110358972989078Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33110358972989078Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33110358972989078Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33213099777130997Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33213099777130997Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33347735462922975Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33347735481136227Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333477354108914061Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)334394121103141944Rat
10450813Scl74Serum cholesterol level QTL 745.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33924839152182792Rat
10450852Stl33Serum triglyceride level QTL 333.40.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)33924839152182792Rat
10450816Scl75Serum cholesterol level QTL 754.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33924839152182792Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)339248391140271184Rat
4889975Bmd81Bone mineral density QTL 814.3tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)33977324751687917Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)34042292185422921Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)34052359354745780Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)34052359364880586Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)34052359392654473Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)34052359392654473Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)343295930108914061Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)343295930163640485Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)343295930163640485Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34540605894467785Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)345406058127023997Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)345406058177699992Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:285
Count of miRNA genes:195
Interacting mature miRNAs:221
Transcripts:ENSRNOT00000011794
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 24 55 39 19 39 4 4 44 8 37 11 4
Low 19 2 2 2 4 7 30 27 4 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ422211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV776506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000011794   ⟹   ENSRNOP00000011794
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl347,439,076 - 47,515,700 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000081682   ⟹   ENSRNOP00000071679
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl347,453,821 - 47,515,700 (+)Ensembl
RefSeq Acc Id: NM_001164073   ⟹   NP_001157545
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,114,303 - 46,190,270 (+)NCBI
Rnor_6.0347,439,076 - 47,515,706 (+)NCBI
Rnor_5.0354,111,767 - 54,188,472 (+)NCBI
RGSC_v3.4343,396,247 - 43,475,491 (+)RGD
Celera345,783,047 - 45,858,966 (+)RGD
Sequence:
RefSeq Acc Id: NM_145788   ⟹   NP_665731
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,652 - 46,190,270 (+)NCBI
Rnor_6.0347,453,882 - 47,515,706 (+)NCBI
Rnor_5.0354,111,767 - 54,188,472 (+)NCBI
RGSC_v3.4343,396,247 - 43,475,491 (+)RGD
Celera345,797,400 - 45,858,966 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006234273   ⟹   XP_006234335
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,114,253 - 46,190,270 (+)NCBI
Rnor_6.0347,439,007 - 47,515,706 (+)NCBI
Rnor_5.0354,111,767 - 54,188,472 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006234274   ⟹   XP_006234336
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,589 - 46,190,270 (+)NCBI
Rnor_6.0347,453,831 - 47,515,706 (+)NCBI
Rnor_5.0354,111,767 - 54,188,472 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104349   ⟹   XP_038960277
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,175,527 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104351   ⟹   XP_038960279
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,605 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104352   ⟹   XP_038960280
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,114,273 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104353   ⟹   XP_038960281
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,589 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104354   ⟹   XP_038960282
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,589 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104355   ⟹   XP_038960283
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,589 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104356   ⟹   XP_038960284
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,589 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104357   ⟹   XP_038960285
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,114,253 - 46,190,270 (+)NCBI
RefSeq Acc Id: XM_039104358   ⟹   XP_038960286
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2346,128,589 - 46,166,591 (+)NCBI
RefSeq Acc Id: XR_591517
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0347,453,831 - 47,515,706 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_665731   ⟸   NM_145788
- Peptide Label: isoform 1
- UniProtKB: Q5HZX1 (UniProtKB/TrEMBL),   Q8VDA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157545   ⟸   NM_001164073
- Peptide Label: isoform 2
- UniProtKB: F1M101 (UniProtKB/TrEMBL),   Q5HZX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234335   ⟸   XM_006234273
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006234336   ⟸   XM_006234274
- Peptide Label: isoform X2
- UniProtKB: F1M101 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011794   ⟸   ENSRNOT00000011794
RefSeq Acc Id: ENSRNOP00000071679   ⟸   ENSRNOT00000081682
RefSeq Acc Id: XP_038960285   ⟸   XM_039104357
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038960280   ⟸   XM_039104352
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960281   ⟸   XM_039104353
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038960283   ⟸   XM_039104355
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038960282   ⟸   XM_039104354
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038960284   ⟸   XM_039104356
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038960286   ⟸   XM_039104358
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038960279   ⟸   XM_039104351
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960277   ⟸   XM_039104349
- Peptide Label: isoform X3
Protein Domains
UBZ1-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692096
Promoter ID:EPDNEW_R2620
Type:initiation region
Name:Tank_2
Description:TRAF family member-associated NFKB activator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2621  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0347,439,029 - 47,439,089EPDNEW
RGD ID:13692097
Promoter ID:EPDNEW_R2621
Type:initiation region
Name:Tank_1
Description:TRAF family member-associated NFKB activator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2620  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0347,453,910 - 47,453,970EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628859 AgrOrtholog
Ensembl Genes ENSRNOG00000008859 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000011794 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071679 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011794 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000081682 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7317281 IMAGE-MGC_LOAD
  IMAGE:7365827 IMAGE-MGC_LOAD
InterPro CALCOCO1/2_Zn_UBZ1 UniProtKB/TrEMBL
  TANK UniProtKB/TrEMBL
  TBD UniProtKB/TrEMBL
KEGG Report rno:252961 UniProtKB/TrEMBL
MGC_CLONE MGC:105308 IMAGE-MGC_LOAD
  MGC:156587 IMAGE-MGC_LOAD
NCBI Gene 252961 ENTREZGENE
PANTHER PTHR15249 UniProtKB/TrEMBL
Pfam TBD UniProtKB/TrEMBL
PhenoGen Tank PhenoGen
PROSITE ZF_UBZ1 UniProtKB/TrEMBL
UniProt F1M101 ENTREZGENE, UniProtKB/TrEMBL
  Q5HZX1 ENTREZGENE, UniProtKB/TrEMBL
  Q8VDA2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A1L1J0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Tank  TRAF family member-associated NFKB activator  Tank  TRAF family member-associated Nf-kappa B activator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Tank  TRAF family member-associated Nf-kappa B activator      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Tank  TRAF family member-associated Nf-kappa B activator      Symbol and Name status set to provisional 70820 PROVISIONAL