Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Map3k20 (mitogen-activated protein kinase kinase kinase 20) Rattus norvegicus
Symbol: Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Description: Predicted to have ATP binding activity; MAP kinase kinase kinase activity; and magnesium ion binding activity. Predicted to be involved in several processes, including activation of JUN kinase activity; cellular response to gamma radiation; and negative regulation of cell cycle. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in centronuclear myopathy 6 with fiber-type disproportion. Orthologous to human MAP3K20 (mitogen-activated protein kinase kinase kinase 20); PARTICIPATES IN p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH bisphenol A; (+)-catechin (ortholog); (-)-anisomycin (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC311743; mitogen-activated protein kinase kinase kinase MLT; MLTK; RGD1561394; similar to MLTK-beta; sterile alpha motif and leucine zipper containing kinase AZK; Zak
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0358,965,025 - 59,120,507 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl358,965,552 - 59,067,369 (+)Ensembl
Rnor_5.0365,435,276 - 65,598,052 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4354,767,724 - 54,915,022 (+)NCBIRGSC3.4rn4RGSC3.4
Celera356,670,166 - 56,831,147 (+)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Map3k20
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561394
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.