(+)-dexrazoxane multiple interactions ISO Pdk1 (Mus musculus) 6480464 [Doxorubicin co-treated with Dexrazoxane] results in increased expression of PDK1 mRNA CTD PMID:26873546 (-)-demecolcine decreases expression ISO PDK1 (Homo sapiens) 6480464 Demecolcine results in decreased expression of PDK1 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate multiple interactions ISO PDK1 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PDK1 mRNA CTD PMID:22079256 (S)-nicotine increases expression ISO Pdk1 (Mus musculus) 6480464 Nicotine results in increased expression of PDK1 mRNA CTD PMID:31945395 1,10-phenanthroline increases expression ISO PDK1 (Homo sapiens) 6480464 1 and 10-phenanthroline results in increased expression of PDK1 mRNA CTD PMID:19502547 1,2-dimethylhydrazine decreases expression ISO Pdk1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PDK1 mRNA CTD PMID:22206623 1,4-benzoquinone multiple interactions ISO PDK1 (Homo sapiens) 6480464 [HIF1A protein co-treated with quinone] results in increased expression of PDK1 protein CTD PMID:30448556 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine decreases expression ISO Pdk1 (Mus musculus) 6480464 Trimetazidine results in decreased expression of PDK1 mRNA CTD PMID:37591408 17beta-estradiol multiple interactions ISO PDK1 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA CTD PMID:20823114 17beta-estradiol increases expression ISO PDK1 (Homo sapiens) 6480464 Estradiol results in increased expression of PDK1 mRNA CTD PMID:31614463 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Pdk1 (Mus musculus) 6480464 2 more ... CTD PMID:21851831 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO PDK1 (Homo sapiens) 6480464 2 more ... CTD PMID:30821169 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO PDK1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:30821169 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO PDK1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:30821169 and PMID:31251971 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO PDK1 (Homo sapiens) 6480464 2 more ... CTD PMID:30821169 and PMID:31251971 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Pdk1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PDK1 mRNA CTD PMID:19933214 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO PDK1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of PDK1 protein CTD PMID:27312872 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Pdk1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PDK1 mRNA CTD PMID:21570461 and PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PDK1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Pdk1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA CTD PMID:19770486 and PMID:21851831 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Pdk1 (Mus musculus) 6480464 2 more ... CTD PMID:21851831 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of PDK1 mRNA CTD PMID:21346803 2-butoxyethanol increases expression ISO Pdk1 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of PDK1 mRNA CTD PMID:19812364 3',5'-cyclic AMP multiple interactions ISO Pdk1 (Mus musculus) 6480464 1 more ... CTD PMID:28887310 3',5'-cyclic AMP affects abundance ISO Pdk1 (Mus musculus) 6480464 PDK1 protein affects the abundance of Cyclic AMP CTD PMID:28887310 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO PDK1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [3 more ... CTD PMID:30821169 3,3',4,4',5-pentachlorobiphenyl increases expression ISO PDK1 (Homo sapiens) 6480464 3 more ... CTD PMID:30821169 3,4-methylenedioxymethamphetamine increases expression ISO Pdk1 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PDK1 mRNA CTD PMID:26251327 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO PDK1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA CTD PMID:28628672 3-phenylprop-2-enal multiple interactions ISO Pdk1 (Mus musculus) 6480464 cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of PDK1 protein] CTD PMID:20467561 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of PDK1 mRNA CTD PMID:30723492 4,4'-sulfonyldiphenol increases expression ISO PDK1 (Homo sapiens) 6480464 bisphenol S results in increased expression of PDK1 protein CTD PMID:34186270 5-azacytidine increases expression ISO PDK1 (Homo sapiens) 6480464 Azacitidine results in increased expression of PDK1 mRNA CTD PMID:20823114 5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid decreases expression ISO PDK1 (Homo sapiens) 6480464 acipimox results in decreased expression of PDK1 mRNA CTD PMID:25352640 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of PDK1 mRNA CTD PMID:31881176 acrylamide decreases expression ISO PDK1 (Homo sapiens) 6480464 Acrylamide results in decreased expression of PDK1 mRNA CTD PMID:32763439 aflatoxin B1 decreases expression ISO Pdk1 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of PDK1 mRNA CTD PMID:19770486 aflatoxin B1 decreases expression ISO PDK1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PDK1 mRNA CTD PMID:21641981 aldehydo-D-glucose multiple interactions EXP 6480464 PDK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose] CTD PMID:14711829 aldehydo-D-glucose multiple interactions ISO PDK1 (Homo sapiens) 6480464 Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 mRNA] and Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] CTD PMID:31654802 aldehydo-D-glucose affects expression EXP 6480464 Glucose affects the expression of PDK1 mRNA CTD PMID:24349266 all-trans-retinoic acid decreases expression ISO Pdk1 (Mus musculus) 6480464 Tretinoin results in decreased expression of PDK1 mRNA CTD PMID:16604517 all-trans-retinoic acid increases expression ISO PDK1 (Homo sapiens) 6480464 Tretinoin results in increased expression of PDK1 mRNA CTD PMID:21934132 alpha-D-galactose multiple interactions ISO PDK1 (Homo sapiens) 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] CTD PMID:31654802 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PDK1 mRNA CTD PMID:16483693 aristolochic acid A decreases expression ISO PDK1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PDK1 mRNA CTD PMID:33212167 Aroclor 1254 decreases expression ISO Pdk1 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of PDK1 mRNA CTD PMID:23650126 arsenite(3-) decreases expression ISO Pdk1 (Mus musculus) 6480464 arsenite results in decreased expression of PDK1 mRNA CTD PMID:33053406 arsenous acid increases expression ISO Pdk1 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of PDK1 mRNA CTD PMID:32112876 ATP multiple interactions ISO Pdk1 (Mus musculus) 6480464 [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium more ... CTD PMID:28887310 ATP affects response to substance ISO Pdk1 (Mus musculus) 6480464 PDK1 protein affects the susceptibility to Adenosine Triphosphate CTD PMID:28887310 avobenzone increases expression ISO PDK1 (Homo sapiens) 6480464 avobenzone results in increased expression of PDK1 mRNA CTD PMID:31016361 benzo[a]pyrene decreases expression ISO PDK1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PDK1 mRNA CTD PMID:20106945 and PMID:21632981 benzo[a]pyrene affects methylation ISO PDK1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PDK1 3' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation ISO PDK1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of PDK1 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO Pdk1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PDK1 mRNA CTD PMID:22610609 benzo[a]pyrene diol epoxide I decreases expression ISO PDK1 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 bilirubin IXalpha decreases expression ISO PDK1 (Homo sapiens) 6480464 Bilirubin results in decreased expression of PDK1 mRNA CTD PMID:20196124 bis(2-ethylhexyl) phthalate decreases expression ISO Pdk1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of PDK1 mRNA CTD PMID:31211961 bisphenol A multiple interactions EXP 6480464 [Fructose co-treated with bisphenol A] results in increased expression of PDK1 protein CTD PMID:26930160 bisphenol A increases expression ISO PDK1 (Homo sapiens) 6480464 bisphenol A results in increased expression of PDK1 protein CTD PMID:37567409 bisphenol A affects expression ISO PDK1 (Homo sapiens) 6480464 bisphenol A affects the expression of PDK1 mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO PDK1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA CTD PMID:28628672 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PDK1 mRNA CTD PMID:27296223 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PDK1 mRNA CTD PMID:12075121 more ... Bisphenol B increases expression ISO PDK1 (Homo sapiens) 6480464 bisphenol B results in increased expression of PDK1 protein CTD PMID:34186270 bisphenol F increases expression ISO PDK1 (Homo sapiens) 6480464 bisphenol F results in increased expression of PDK1 protein CTD PMID:34186270 bucladesine multiple interactions ISO PDK1 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA CTD PMID:20823114 butanal decreases expression ISO PDK1 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of PDK1 mRNA CTD PMID:26079696 cadmium atom multiple interactions ISO PDK1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PDK1 mRNA and PDK1 promotes the reaction [Cadmium results in increased expression of MT1A mRNA] CTD PMID:28632756 and PMID:35301059 cadmium dichloride decreases expression ISO PDK1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of PDK1 mRNA CTD PMID:33129824 cadmium dichloride multiple interactions ISO PDK1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PDK1 mRNA CTD PMID:35301059 calcium atom multiple interactions ISO PDK1 (Homo sapiens) 6480464 PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 calcium atom affects abundance ISO Pdk1 (Mus musculus) 6480464 PDK1 protein affects the abundance of Calcium CTD PMID:28887310 calcium atom multiple interactions ISO Pdk1 (Mus musculus) 6480464 1 more ... CTD PMID:28887310 calcium(0) multiple interactions ISO PDK1 (Homo sapiens) 6480464 PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 calcium(0) affects abundance ISO Pdk1 (Mus musculus) 6480464 PDK1 protein affects the abundance of Calcium CTD PMID:28887310 calcium(0) multiple interactions ISO Pdk1 (Mus musculus) 6480464 1 more ... CTD PMID:28887310 carbamazepine affects expression ISO PDK1 (Homo sapiens) 6480464 Carbamazepine affects the expression of PDK1 mRNA CTD PMID:25979313 carbon nanotube decreases expression ISO Pdk1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 CGP 52608 multiple interactions ISO PDK1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PDK1 gene] CTD PMID:28238834 chlorpromazine increases expression EXP 6480464 Chlorpromazine results in increased expression of PDK1 mRNA CTD PMID:25596134 chlorpyrifos increases expression ISO Pdk1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of PDK1 mRNA CTD PMID:37019170 cisplatin decreases expression ISO PDK1 (Homo sapiens) 6480464 Cisplatin results in decreased expression of PDK1 mRNA CTD PMID:24280081 and PMID:25596134 cisplatin decreases expression ISO Pdk1 (Mus musculus) 6480464 Cisplatin results in decreased expression of PDK1 mRNA CTD PMID:24280081 clodronic acid decreases expression ISO PDK1 (Homo sapiens) 6480464 Clodronic Acid results in decreased expression of PDK1 mRNA CTD PMID:25596134 cobalt atom multiple interactions ISO PDK1 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in increased expression of PDK1 mRNA CTD PMID:20105288 cobalt atom increases expression ISO PDK1 (Homo sapiens) 6480464 Cobalt results in increased expression of PDK1 mRNA CTD PMID:32827984 cobalt dichloride multiple interactions ISO PDK1 (Homo sapiens) 6480464 zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] CTD PMID:22202117 cobalt dichloride increases expression ISO PDK1 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of PDK1 mRNA CTD PMID:19502547 more ... cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of PDK1 mRNA CTD PMID:21558026 and PMID:24386269 cobalt(2+) sulfate increases expression ISO PDK1 (Homo sapiens) 6480464 cobalt sulfate results in increased expression of PDK1 mRNA CTD PMID:19502547 colforsin daropate hydrochloride affects response to substance ISO Pdk1 (Mus musculus) 6480464 PDK1 protein affects the susceptibility to Colforsin CTD PMID:28887310 colforsin daropate hydrochloride multiple interactions ISO Pdk1 (Mus musculus) 6480464 [PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP and tubacin affects the reaction [[PDK1 protein affects the susceptibility to Colforsin] which affects the abundance of Cyclic AMP] CTD PMID:28887310 copper atom increases expression EXP 6480464 Copper results in increased expression of PDK1 mRNA CTD PMID:22465980 copper(0) increases expression EXP 6480464 Copper results in increased expression of PDK1 mRNA CTD PMID:22465980 corticosterone multiple interactions ISO Pdk1 (Mus musculus) 6480464 [Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein] which results in increased phosphorylation of and results in increased activity of SGK1 protein and Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein CTD PMID:21655274 curcumin multiple interactions ISO PDK1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] more ... CTD PMID:17171638 curcumin increases phosphorylation ISO PDK1 (Homo sapiens) 6480464 Curcumin results in increased phosphorylation of PDK1 protein CTD PMID:17171638 cyclosporin A decreases expression ISO PDK1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PDK1 mRNA CTD PMID:21632981 and PMID:25562108 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of PDK1 mRNA CTD PMID:25596134 D-glucose multiple interactions EXP 6480464 PDK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose] CTD PMID:14711829 D-glucose multiple interactions ISO PDK1 (Homo sapiens) 6480464 Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 mRNA] and Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] CTD PMID:31654802 D-glucose affects expression EXP 6480464 Glucose affects the expression of PDK1 mRNA CTD PMID:24349266 DDT increases expression ISO PDK1 (Homo sapiens) 6480464 DDT results in increased expression of PDK1 mRNA CTD PMID:31724279 DDT multiple interactions ISO PDK1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of PDK1 mRNA] more ... CTD PMID:31724279 decabromodiphenyl ether decreases expression ISO Pdk1 (Mus musculus) 6480464 decabromobiphenyl ether results in decreased expression of PDK1 mRNA CTD PMID:30468867 deguelin decreases expression ISO PDK1 (Homo sapiens) 6480464 deguelin metabolite results in decreased expression of PDK1 protein and deguelin results in decreased expression of PDK1 protein CTD PMID:19139008 desferrioxamine B increases expression ISO PDK1 (Homo sapiens) 6480464 Deferoxamine results in increased expression of PDK1 mRNA CTD PMID:21558026 dexamethasone increases phosphorylation ISO Pdk1 (Mus musculus) 6480464 Dexamethasone results in increased phosphorylation of PDK1 protein CTD PMID:21655274 dexamethasone multiple interactions ISO PDK1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA CTD PMID:28628672 dexamethasone multiple interactions ISO Pdk1 (Mus musculus) 6480464 wortmannin inhibits the reaction [Dexamethasone results in increased phosphorylation of PDK1 protein] CTD PMID:21655274 diarsenic trioxide increases expression ISO Pdk1 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of PDK1 mRNA CTD PMID:32112876 dibutyl phthalate decreases expression ISO Pdk1 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of PDK1 mRNA CTD PMID:21266533 dieldrin decreases expression EXP 6480464 Dieldrin results in decreased expression of PDK1 mRNA CTD PMID:23153324 dioxygen multiple interactions ISO PDK1 (Homo sapiens) 6480464 [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] more ... CTD PMID:17671207 more ... dioxygen increases expression ISO PDK1 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of PDK1 mRNA CTD PMID:17175027 more ... dioxygen increases expression ISO Pdk1 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of PDK1 mRNA CTD PMID:20880076 dorsomorphin multiple interactions ISO PDK1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions ISO Pdk1 (Mus musculus) 6480464 [Doxorubicin co-treated with Dexrazoxane] results in increased expression of PDK1 mRNA CTD PMID:26873546 doxorubicin decreases expression ISO PDK1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PDK1 mRNA CTD PMID:29803840 doxorubicin increases expression ISO PDK1 (Homo sapiens) 6480464 Doxorubicin results in increased expression of PDK1 mRNA CTD PMID:28940058 doxorubicin decreases expression ISO Pdk1 (Mus musculus) 6480464 Doxorubicin results in decreased expression of PDK1 mRNA CTD PMID:26873546 duvoglustat multiple interactions ISO Pdk1 (Mus musculus) 6480464 [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] CTD PMID:25446853 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of PDK1 mRNA CTD PMID:29391264 Erionite increases expression ISO Pdk1 (Mus musculus) 6480464 erionite results in increased expression of PDK1 mRNA CTD PMID:29279043 ethanol affects expression ISO Pdk1 (Mus musculus) 6480464 Ethanol affects the expression of PDK1 mRNA CTD PMID:30319688 ethyl methanesulfonate decreases expression ISO PDK1 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of PDK1 mRNA CTD PMID:23649840 etoposide decreases expression ISO PDK1 (Homo sapiens) 6480464 Etoposide results in decreased expression of PDK1 mRNA CTD PMID:29397400 fenofibrate decreases expression EXP 6480464 Fenofibrate results in decreased expression of PDK1 mRNA CTD PMID:25596134 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of PDK1 mRNA CTD PMID:34044035 fluoranthene multiple interactions ISO Pdk1 (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of PDK1 mRNA CTD PMID:28329830 folic acid decreases expression ISO Pdk1 (Mus musculus) 6480464 Folic Acid results in decreased expression of PDK1 mRNA CTD PMID:25629700 formaldehyde decreases expression ISO PDK1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of PDK1 mRNA CTD PMID:23649840 formaldehyde increases expression ISO Pdk1 (Mus musculus) 6480464 Formaldehyde results in increased expression of PDK1 protein CTD PMID:33259821 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of PDK1 protein CTD PMID:33259821 fructose multiple interactions EXP 6480464 [Fructose co-treated with bisphenol A] results in increased expression of PDK1 protein CTD PMID:26930160 Fusaric acid multiple interactions ISO PDK1 (Homo sapiens) 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] more ... CTD PMID:31654802 Fusaric acid affects expression ISO Pdk1 (Mus musculus) 6480464 Fusaric Acid affects the expression of PDK1 protein CTD PMID:32156565 Fusaric acid increases expression ISO PDK1 (Homo sapiens) 6480464 Fusaric Acid results in increased expression of PDK1 mRNA and Fusaric Acid results in increased expression of PDK1 protein CTD PMID:31654802 galactose multiple interactions ISO PDK1 (Homo sapiens) 6480464 Galactose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] CTD PMID:31654802 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PDK1 mRNA CTD PMID:22061828 glucose multiple interactions EXP 6480464 PDK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose] CTD PMID:14711829 glucose multiple interactions ISO PDK1 (Homo sapiens) 6480464 Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 mRNA] and Glucose affects the reaction [Fusaric Acid results in increased expression of PDK1 protein] CTD PMID:31654802 glucose affects expression EXP 6480464 Glucose affects the expression of PDK1 mRNA CTD PMID:24349266 glutathione multiple interactions ISO PDK1 (Homo sapiens) 6480464 Glutathione inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] CTD PMID:17171638 glyphosate decreases expression ISO Pdk1 (Mus musculus) 6480464 Glyphosate results in decreased expression of PDK1 mRNA CTD PMID:36572786 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of PDK1 mRNA CTD PMID:24349266 ifosfamide decreases expression ISO PDK1 (Homo sapiens) 6480464 Ifosfamide results in decreased expression of PDK1 mRNA CTD PMID:25596134 indometacin multiple interactions ISO PDK1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDK1 mRNA CTD PMID:28628672 inulin multiple interactions ISO Pdk1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PDK1 mRNA CTD PMID:36331819 ionomycin multiple interactions ISO PDK1 (Homo sapiens) 6480464 PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 isoliquiritigenin decreases phosphorylation ISO PDK1 (Homo sapiens) 6480464 isoliquiritigenin results in decreased phosphorylation of PDK1 protein CTD PMID:25094029 isoprenaline increases expression ISO Pdk1 (Mus musculus) 6480464 Isoproterenol results in increased expression of PDK1 mRNA CTD PMID:20003209 ivermectin decreases expression ISO PDK1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of PDK1 protein CTD PMID:32959892 lead(0) decreases expression ISO PDK1 (Homo sapiens) 6480464 Lead results in decreased expression of PDK1 mRNA CTD PMID:19921347 lipopolysaccharide multiple interactions ISO Pdk1 (Mus musculus) 6480464 cinnamaldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of PDK1 protein] CTD PMID:20467561 lipopolysaccharide increases phosphorylation ISO Pdk1 (Mus musculus) 6480464 Lipopolysaccharides results in increased phosphorylation of PDK1 protein CTD PMID:20467561 LY294002 multiple interactions ISO PDK1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the localization of [PDK1 protein binds to AKT1 protein] more ... CTD PMID:20361045 manganese atom increases expression ISO PDK1 (Homo sapiens) 6480464 Manganese results in increased expression of PDK1 mRNA CTD PMID:17175027 manganese(0) increases expression ISO PDK1 (Homo sapiens) 6480464 Manganese results in increased expression of PDK1 mRNA CTD PMID:17175027 manganese(II) chloride increases expression ISO PDK1 (Homo sapiens) 6480464 manganese chloride results in increased expression of PDK1 mRNA CTD PMID:17175027 medroxyprogesterone acetate multiple interactions ISO PDK1 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA CTD PMID:20823114 meldonium increases expression ISO Pdk1 (Mus musculus) 6480464 3-(2 more ... CTD PMID:32389661 mercury dibromide decreases expression ISO PDK1 (Homo sapiens) 6480464 mercuric bromide results in decreased expression of PDK1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO PDK1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA CTD PMID:27188386 metformin affects expression EXP 6480464 Metformin affects the expression of PDK1 mRNA CTD PMID:25596134 metformin increases expression EXP 6480464 Metformin results in increased expression of PDK1 mRNA CTD PMID:31324951 methotrexate affects response to substance ISO PDK1 (Homo sapiens) 6480464 PDK1 protein affects the susceptibility to Methotrexate CTD PMID:16217747 methyl methanesulfonate decreases expression ISO PDK1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of PDK1 mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO PDK1 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of PDK1 mRNA CTD PMID:23179753 and PMID:27188386 monosodium L-glutamate multiple interactions ISO Pdk1 (Mus musculus) 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of PDK1 mRNA CTD PMID:19001666 morin multiple interactions EXP 6480464 morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] CTD PMID:19931519 morphine decreases expression EXP 6480464 Morphine results in decreased expression of PDK1 protein CTD PMID:23056601 N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide multiple interactions ISO Pdk1 (Mus musculus) 6480464 N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] CTD PMID:28887310 N-acetyl-L-cysteine multiple interactions ISO PDK1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:17171638 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Pdk1 (Mus musculus) 6480464 MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA] CTD PMID:25566086 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO Pdk1 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA CTD PMID:25566086 N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of PDK1 mRNA CTD PMID:16525678 N-nitrosodiethylamine multiple interactions ISO Pdk1 (Mus musculus) 6480464 CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of PDK1 protein] CTD PMID:20583210 N-nitrosodiethylamine multiple interactions EXP 6480464 morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] CTD PMID:19931519 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of PDK1 protein modified form CTD PMID:19931519 N-nitrosodiethylamine increases phosphorylation ISO Pdk1 (Mus musculus) 6480464 Diethylnitrosamine results in increased phosphorylation of PDK1 protein CTD PMID:20583210 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of PDK1 mRNA CTD PMID:22110744 nickel dichloride increases expression ISO PDK1 (Homo sapiens) 6480464 nickel chloride results in increased expression of PDK1 mRNA CTD PMID:21455298 niclosamide multiple interactions ISO PDK1 (Homo sapiens) 6480464 Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] CTD PMID:36318118 nicotine increases expression ISO Pdk1 (Mus musculus) 6480464 Nicotine results in increased expression of PDK1 mRNA CTD PMID:31945395 Nonylphenol decreases expression EXP 6480464 nonylphenol results in decreased expression of PDK1 mRNA CTD PMID:27832966 ochratoxin A increases phosphorylation EXP 6480464 ochratoxin A results in increased phosphorylation of PDK1 protein CTD PMID:17651772 ochratoxin A affects expression ISO PDK1 (Homo sapiens) 6480464 ochratoxin A affects the expression of PDK1 protein CTD PMID:30876885 ochratoxin A affects phosphorylation ISO PDK1 (Homo sapiens) 6480464 ochratoxin A affects the phosphorylation of PDK1 protein CTD PMID:25002221 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of PDK1 protein CTD PMID:17651772 p-chloromercuribenzoic acid decreases expression ISO PDK1 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of PDK1 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO PDK1 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA CTD PMID:27188386 paclitaxel multiple interactions ISO PDK1 (Homo sapiens) 6480464 [PDK1 protein binds to AKT1 protein] results in decreased susceptibility to [Paclitaxel co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] and [PDK1 protein binds to AKT1 protein] which results in decreased susceptibility to Paclitaxel CTD PMID:20361045 paracetamol affects expression ISO Pdk1 (Mus musculus) 6480464 Acetaminophen affects the expression of PDK1 mRNA CTD PMID:17562736 paracetamol decreases expression ISO PDK1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PDK1 mRNA CTD PMID:25704631 perfluorononanoic acid decreases expression EXP 6480464 perfluoro-n-nonanoic acid results in decreased expression of PDK1 protein modified form CTD PMID:22387981 perfluorooctane-1-sulfonic acid multiple interactions ISO Pdk1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PDK1 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of PDK1 mRNA CTD PMID:36331819 perfluorooctanoic acid multiple interactions ISO Pdk1 (Mus musculus) 6480464 Dietary Fats and Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of PDK1 mRNA] CTD PMID:23626681 permethrin multiple interactions ISO Pdk1 (Mus musculus) 6480464 Permethrin inhibits the reaction [INS1 protein results in increased phosphorylation of PDK1 protein] CTD PMID:24911977 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of PDK1 mRNA CTD PMID:19162173 phenylmercury acetate decreases expression ISO PDK1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of PDK1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO PDK1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDK1 mRNA CTD PMID:27188386 phosphane affects expression EXP 6480464 phosphine affects the expression of PDK1 mRNA CTD PMID:34427094 pirinixic acid multiple interactions ISO Pdk1 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PDK1 mRNA CTD PMID:19710929 pirinixic acid decreases expression ISO Pdk1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of PDK1 mRNA CTD PMID:23811191 pirinixic acid increases expression ISO Pdk1 (Mus musculus) 6480464 pirinixic acid results in increased expression of PDK1 mRNA CTD PMID:17426115 potassium chromate increases expression ISO PDK1 (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of PDK1 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO PDK1 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PDK1 mRNA CTD PMID:22079256 propiconazole decreases expression ISO Pdk1 (Mus musculus) 6480464 propiconazole results in decreased expression of PDK1 mRNA CTD PMID:21278054 quercetin decreases expression ISO PDK1 (Homo sapiens) 6480464 Quercetin results in decreased expression of PDK1 mRNA CTD PMID:21632981 quinolin-8-ol decreases expression ISO PDK1 (Homo sapiens) 6480464 Oxyquinoline results in decreased expression of PDK1 mRNA CTD PMID:21632981 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of PDK1 protein CTD PMID:24395567 resveratrol multiple interactions EXP 6480464 sirtinol inhibits the reaction [resveratrol results in decreased expression of PDK1 protein] CTD PMID:24395567 rotenone multiple interactions ISO PDK1 (Homo sapiens) 6480464 [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] CTD PMID:17671207 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PDK1 mRNA CTD PMID:28374803 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO PDK1 (Homo sapiens) 6480464 Buthionine Sulfoximine promotes the reaction [Curcumin results in increased phosphorylation of PDK1 protein] CTD PMID:17171638 SB 431542 multiple interactions ISO PDK1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide decreases expression ISO PDK1 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of PDK1 mRNA CTD PMID:25895662 sirtinol multiple interactions EXP 6480464 sirtinol inhibits the reaction [resveratrol results in decreased expression of PDK1 protein] CTD PMID:24395567 sodium arsenite increases expression ISO PDK1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of PDK1 mRNA CTD PMID:27287256 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PDK1 mRNA CTD PMID:35314868 sodium fluoride decreases expression ISO Pdk1 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of PDK1 protein CTD PMID:28918527 streptozocin multiple interactions ISO Pdk1 (Mus musculus) 6480464 [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] and [Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA CTD PMID:25446853 sunitinib increases expression ISO PDK1 (Homo sapiens) 6480464 Sunitinib results in increased expression of PDK1 mRNA CTD PMID:31533062 tetrachloromethane decreases expression ISO Pdk1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of PDK1 mRNA CTD PMID:27339419 and PMID:31919559 thapsigargin multiple interactions ISO Pdk1 (Mus musculus) 6480464 PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium] and tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]] CTD PMID:28887310 thimerosal decreases expression ISO PDK1 (Homo sapiens) 6480464 Thimerosal results in decreased expression of PDK1 mRNA CTD PMID:27188386 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PDK1 mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO Pdk1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of PDK1 mRNA CTD PMID:23557971 and PMID:27760801 trichostatin A increases expression ISO PDK1 (Homo sapiens) 6480464 trichostatin A results in increased expression of PDK1 mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO PDK1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA CTD PMID:27188386 triclosan decreases expression ISO PDK1 (Homo sapiens) 6480464 Triclosan results in decreased expression of PDK1 mRNA CTD PMID:30510588 Triptolide decreases expression ISO Pdk1 (Mus musculus) 6480464 triptolide results in decreased expression of PDK1 mRNA CTD PMID:32835833 triptonide decreases expression ISO Pdk1 (Mus musculus) 6480464 triptonide results in decreased expression of PDK1 mRNA CTD PMID:33045310 tubastatin A multiple interactions ISO Pdk1 (Mus musculus) 6480464 tubastatin A affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] CTD PMID:28887310 Tungsten carbide multiple interactions ISO PDK1 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which results in increased expression of PDK1 mRNA CTD PMID:20105288 Tungsten carbide increases expression ISO PDK1 (Homo sapiens) 6480464 tungsten carbide results in increased expression of PDK1 mRNA CTD PMID:20105288 ubiquinone-0 decreases expression ISO PDK1 (Homo sapiens) 6480464 ubiquinone-O results in decreased expression of PDK1 protein CTD PMID:36847822 undecane decreases expression EXP 6480464 undecane results in decreased expression of PDK1 protein CTD PMID:17337753 urethane decreases expression ISO PDK1 (Homo sapiens) 6480464 Urethane results in decreased expression of PDK1 mRNA CTD PMID:28818685 usnic acid decreases phosphorylation ISO PDK1 (Homo sapiens) 6480464 usnic acid results in decreased phosphorylation of PDK1 protein CTD PMID:25078063 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of PDK1 mRNA CTD PMID:24136188 valproic acid increases expression ISO Pdk1 (Mus musculus) 6480464 Valproic Acid results in increased expression of PDK1 mRNA CTD PMID:24489787 valproic acid multiple interactions ISO PDK1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDK1 mRNA CTD PMID:27188386 valproic acid decreases expression ISO PDK1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PDK1 mRNA CTD PMID:23179753 and PMID:27188386 valproic acid increases expression ISO PDK1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of PDK1 mRNA CTD PMID:23179753 more ... vincristine decreases expression ISO PDK1 (Homo sapiens) 6480464 Vincristine results in decreased expression of PDK1 mRNA CTD PMID:23649840 vorinostat multiple interactions ISO PDK1 (Homo sapiens) 6480464 vorinostat inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 protein] CTD PMID:26305601 vorinostat decreases expression ISO PDK1 (Homo sapiens) 6480464 vorinostat results in decreased expression of PDK1 mRNA CTD PMID:27188386 wortmannin multiple interactions ISO Pdk1 (Mus musculus) 6480464 wortmannin inhibits the reaction [Dexamethasone results in increased phosphorylation of PDK1 protein] CTD PMID:21655274 Yessotoxin increases expression ISO PDK1 (Homo sapiens) 6480464 yessotoxin analog results in increased expression of PDK1 mRNA CTD PMID:30679557 zinc atom increases expression ISO PDK1 (Homo sapiens) 6480464 Zinc deficiency results in increased expression of PDK1 mRNA CTD PMID:18356318 zinc dichloride multiple interactions ISO PDK1 (Homo sapiens) 6480464 zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] CTD PMID:22202117 zinc(0) increases expression ISO PDK1 (Homo sapiens) 6480464 Zinc deficiency results in increased expression of PDK1 mRNA CTD PMID:18356318