Epfw1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Epfw1 (Epididymal fat weight QTL 1) Rattus norvegicus

Symbol: Epfw1
Name: Epididymal fat weight QTL 1
RGD ID: 1582239
Previously known as: Epid. Fat weight (ln); Epid. Fat wt (ln)
Trait: epididymal fat pad mass   (VT:0010421)    
Measurement Type: epididymal fat pad weight to body weight ratio   (CMO:0000658)    
LOD Score: 4.5
P Value: 6.0E-4
Variance: 16.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8373,592,512 - 136,118,980RGD_MAPPER_PIPELINE
mRatBN7.2353,184,593 - 115,665,732RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0354,630,948 - 119,830,094RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0361,249,840 - 126,355,468RGDRnor5.0
RGSC_v3.4350,522,618 - 116,023,640RGDRGSC3.4
RGSC_v3.1350,418,991 - 115,929,213RGD
Cross Type: intercross
Strains Crossed: PD/Cub BN/Cub 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Epfw1RatMetabolic Syndrome  IDA 1580752 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Epfw1Ratabnormal abdominal fat pad morphology  IAGP 1580752 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Epfw1Ratepididymal fat pad weight to body weight ratio  IDA 1580752 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Epfw1Ratcontrolled sucrose content diet  IDA 1580752 RGD 
Epfw1Ratdexamethasone  IDA 1580752 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Epfw1Ratpost excision weight measurement  IDA 1580752 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Epfw1RatBN/Cub  IEA 1580752 RGD 
Epfw1RatPD/Cub  IEA 1580752 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Epfw1Ratepididymal fat pad mass  IDA 1580752 RGD 


#
Reference Title
Reference Citation
1. Dynamic genetic architecture of metabolic syndrome attributes in the rat. Seda O, etal., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22.


1 to 20 of 1120 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
15976994932414N04RiklRIKEN cDNA 4932414N04 gene like35328445453518848Rat
1564400Eif5-ps1eukaryotic translation initiation factor 5, pseudogene 135356636553569726Rat
1561599Cers6ceramide synthase 635363063753879692Rat
1589692Ybx1-ps9Y box binding protein 1, pseudogene 935389125953892680Rat
727920Nostrinnitric oxide synthase trafficking35390474653970995Rat
1307811Spc25SPC25 component of NDC80 kinetochore complex35393001353988940Rat
69398G6pc2glucose-6-phosphatase catalytic subunit 235399982154005539Rat
619930Abcb11ATP binding cassette subfamily B member 1135401685454112797Rat
620655Dhrs9dehydrogenase/reductase 935414783454170052Rat
68407Lrp2LDL receptor related protein 235418930554346769Rat
40992206Cfl1-ps10cofilin 1, pseudogene 1035435215454376010Rat
11408567LOC108350390uncharacterized LOC10835039035439624654402640Rat
1310718Bbs5Bardet-Biedl syndrome 535441042954431831Rat
620852Klhl41kelch-like family member 4135443429154447415Rat
1563531Fastkd1FAST kinase domains 135444971054475624Rat
620315Ppigpeptidylprolyl isomerase G35448402354512929Rat
1308818Cfap210cilia and flagella associated protein 21035452045554554677Rat
1359274Phospho2phosphatase, orphan 235455482954561990Rat
1307166Klhl23kelch-like family member 2335458078854594530Rat
620804Ssbsmall RNA binding exonuclease protection factor La35461661654626203Rat

1 to 20 of 1120 rows
1 to 20 of 1156 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10100D3Mco22903114583342114583648Ratregion
10233D3Arb1119639621091396211109Ratregion
10234D3Mgh2813939621095996211098Ratregion
10275D3Wox1519536943021969430414Ratregion
10293D3Mit716538987820789878372Ratregion
33826D3Mit69539613869996138794Ratregion
33838D3Mit181883112287552112287746Ratregion
33901D3Mit121513114297399114297550Ratregion
34146D3Mgh69935318459353184692Ratregion
34228D3Mgh513139853525598535386Ratregion
34242D3Mgh131343112272331112272465Ratregion
34250D3Mgh121763112272331112272507Ratregion
34507D3Mgh111583106320129106320287Ratregion
33608D3Mit141813115638168115638351Ratregion
33668D3Mit13813115638231115638314Ratregion
33684D3Mit1614839299976092999908Ratregion
33774D3Mit1514039485676394856903Ratregion
36077D3Rat2816938965223689652405Ratregion
36183D3Rat3617838036732980367507Ratregion
36261D3Rat3216836822606368226231Ratregion
1 to 20 of 1156 rows

Flank 1: (D3Mgh6)
Rat AssemblyChrPosition (strand)Source
GRCr8373,592,512 - 73,592,611 (+)Marker Load Pipeline
mRatBN7.2353,184,593 - 53,184,692 (+)MAPPER
Rnor_6.0354,630,948 - 54,631,046NCBI
Rnor_5.0361,249,840 - 61,249,938UniSTS
RGSC_v3.4350,522,619 - 50,522,717UniSTS
RGSC_v3.4350,522,618 - 50,522,717RGD
RGSC_v3.1350,418,991 - 50,419,089RGD
Celera352,752,755 - 52,752,853UniSTS
RH 3.4 Map4528.72UniSTS
RH 3.4 Map4528.72RGD
SHRSP x BN Map336.0899UniSTS
SHRSP x BN Map336.0899RGD
FHH x ACI Map339.47RGD
Cytogenetic Map3 RGD
Flank 2: (D3Rat257)
Rat AssemblyChrPosition (strand)Source
GRCr83136,118,748 - 136,118,980 (+)Marker Load Pipeline
mRatBN7.23115,665,500 - 115,665,732 (+)MAPPER
Rnor_6.03119,829,863 - 119,830,094NCBI
Rnor_5.03126,355,237 - 126,355,468UniSTS
RGSC_v3.43116,023,408 - 116,023,640RGD
RGSC_v3.43116,023,409 - 116,023,640UniSTS
RGSC_v3.13115,928,981 - 115,929,213RGD
Celera3114,495,720 - 114,495,962UniSTS
RH 2.0 Map3674.0RGD
SHRSP x BN Map355.1498RGD


1 to 10 of 82 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3102200529115665732Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat

1 to 10 of 82 rows


Note Type Note Reference
qtl_cross_type intercross  
qtl_general rats were on a high sucrose diet (HSD; 70% calories as sucrose) for 1 week; while still on sucrose diet, dexamethasone (DEX) was given in drinking water (0.026mg/ml) for 3 days then these animals were killed and the epididymal fat pad weight was determined 1580752
qtl_statistics_details specific pairs of variables were compared by one or two way ANOVA with post hoc Tukey's honest significance difference test; linkage analysis was done on logarithm-transformed values 1580752