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Gene: Adra2b (adrenoceptor alpha 2B) Rattus norvegicus
Symbol: Adra2b
Name: adrenoceptor alpha 2B
RGD ID: 2057
Description: Exhibits alpha2-adrenergic receptor activity. Involved in several processes, including activation of MAPK activity; female pregnancy; and regulation of smooth muscle contraction. Predicted to localize to cell surface and integral component of plasma membrane. Used to study hypertension. Human ortholog(s) of this gene implicated in diabetic neuropathy; hypertension; myocardial infarction; obesity; and type 2 diabetes mellitus. Orthologous to human ADRA2B (adrenoceptor alpha 2B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; C60 fullerene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adrenergic alpha2B- receptor class III; adrenergic receptor, alpha 2b; adrenergic, alpha-2B-, receptor; Adrenergic, alpha2B-, receptor class III; alpha-2B adrenergic receptor; alpha-2B adrenoceptor; alpha-2B adrenoreceptor; alpha-2BAR
Homo sapiens (human) : ADRA2B (adrenoceptor alpha 2B)  HGNC  Alliance
Mus musculus (house mouse) : Adra2b (adrenergic receptor, alpha 2b)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra2b (adrenoceptor alpha 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2B (adrenoceptor alpha 2B)
Canis lupus familiaris (dog) : ADRA2B (adrenoceptor alpha 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra2b (adrenoceptor alpha 2B)
Sus scrofa (pig) : ADRA2B (adrenoceptor alpha 2B)
Chlorocebus sabaeus (African green monkey) : ADRA2B (adrenoceptor alpha 2B)
Heterocephalus glaber (naked mole-rat) : Adra2b (adrenoceptor alpha 2B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03119,805,941 - 119,809,987 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,805,941 - 119,809,987 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,332,318 - 126,336,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,867,357 - 114,869,680 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13114,772,929 - 114,775,253 (+)NCBI
Celera3113,423,833 - 113,427,879 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adra2b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2057
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.