Or4k49 (olfactory receptor family 4 subfamily K member 49) - Rat Genome Database

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Gene: Or4k49 (olfactory receptor family 4 subfamily K member 49) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or4k49
Name: olfactory receptor family 4 subfamily K member 49
RGD ID: 1332807
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 770; olfactory receptor gene Olr770; olfactory receptor Olr770; Olr770
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83118,691,216 - 118,692,154 (+)NCBIGRCr8
mRatBN7.2398,236,692 - 98,237,630 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl398,233,022 - 98,238,433 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3101,800,157 - 101,801,095 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03110,399,160 - 110,400,098 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03108,159,284 - 108,160,222 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03102,841,615 - 102,842,553 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3102,841,615 - 102,842,553 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03109,437,089 - 109,438,027 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4397,220,059 - 97,220,997 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1397,116,486 - 97,117,425 (+)NCBI
Celera397,240,051 - 97,240,989 (+)NCBICelera
Cytogenetic Map3q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4k49Ratdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or4k49Ratdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or4k49RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or4k49RatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or4k49RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or4k49Ratsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or4k49Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4k49Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Or4k49Ratmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or4k49Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or4k49Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Or4k49Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4k49RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or4k49RatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or4k49Ratolfactory receptor activity enablesIBAMGI:3030568 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or4k49Ratolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or4k49Ratolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4k49Rattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Or4k49
5 total Variants

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:14
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000075178
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 39 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat

1 to 10 of 39 rows



appendage
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
respiratory system
1 1 2 2 1 1 1 3 1 1 1


RefSeq Transcripts NM_001000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000075178   ⟹   ENSRNOP00000064909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3102,841,615 - 102,842,553 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094512   ⟹   ENSRNOP00000086067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl398,233,101 - 98,238,433 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112635   ⟹   ENSRNOP00000083724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl398,233,022 - 98,238,433 (+)Ensembl
RefSeq Acc Id: NM_001000372   ⟹   NP_001000372
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83118,691,216 - 118,692,154 (+)NCBI
mRatBN7.2398,236,692 - 98,237,630 (+)NCBI
Rnor_6.03102,841,615 - 102,842,553 (+)NCBI
Rnor_5.03109,437,089 - 109,438,027 (+)NCBI
RGSC_v3.4397,220,059 - 97,220,997 (+)RGD
Celera397,240,051 - 97,240,989 (+)RGD
Sequence:
Protein RefSeqs NP_001000372 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000083724
  ENSRNOP00000083724.1
  ENSRNOP00000086067.1
RefSeq Acc Id: NP_001000372   ⟸   NM_001000372
- UniProtKB: A0A8I5ZZW0 (UniProtKB/TrEMBL),   A6HP31 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064909   ⟸   ENSRNOT00000075178
Ensembl Acc Id: ENSRNOP00000083724   ⟸   ENSRNOT00000112635
Ensembl Acc Id: ENSRNOP00000086067   ⟸   ENSRNOT00000094512
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-M0R669-F1-model_v2 AlphaFold M0R669 1-312 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-48433 BioCyc
Ensembl Genes ENSRNOG00000047449 Ensembl
  ENSRNOG00000068386 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000073817 ENTREZGENE
Ensembl Transcript ENSRNOT00000094512.1 UniProtKB/TrEMBL
  ENSRNOT00000112635 ENTREZGENE
  ENSRNOT00000112635.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
KEGG Report rno:296023 UniProtKB/TrEMBL
NCBI Gene 296023 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4k49 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047449 RatGTEx
  ENSRNOG00000068386 RatGTEx
  ENSRNOG00000073817 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I5ZZW0 ENTREZGENE, UniProtKB/TrEMBL
  A6HP31 ENTREZGENE, UniProtKB/TrEMBL
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or4k49  olfactory receptor family 4 subfamily K member 49  Olr770  olfactory receptor 770  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr770  olfactory receptor 770   Olr770_predicted  olfactory receptor 770 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr770_predicted  olfactory receptor 770 (predicted)      Symbol and Name status set to approved 70820 APPROVED