Tspan18 (tetraspanin 18) - Rat Genome Database

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Gene: Tspan18 (tetraspanin 18) Rattus norvegicus
Analyze
Symbol: Tspan18
Name: tetraspanin 18
RGD ID: 1560411
Description: Predicted to be involved in regulation of sprouting angiogenesis. Predicted to act upstream of or within several processes, including calcium-ion regulated exocytosis; hemostasis; and inflammatory response. Predicted to be located in membrane. Orthologous to human TSPAN18 (tetraspanin 18); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC311210; RGD1560411; similar to Hypothetical protein 6720430O15; tetraspanin-18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8399,615,465 - 99,755,270 (-)NCBIGRCr8
mRatBN7.2379,160,060 - 79,299,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,161,662 - 79,299,852 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx382,634,272 - 82,774,000 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0391,233,326 - 91,373,052 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,085,209 - 89,224,609 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,097,068 - 82,236,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,097,068 - 82,236,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0388,799,484 - 88,939,072 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4377,602,718 - 77,742,512 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera378,363,376 - 78,502,825 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
decabromodiphenyl ether  (EXP)
dibenz[a,h]anthracene  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
fipronil  (EXP)
fulvestrant  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
hydralazine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP)
PCB138  (ISO)
pentanal  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Tspan18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8399,615,465 - 99,755,270 (-)NCBIGRCr8
mRatBN7.2379,160,060 - 79,299,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,161,662 - 79,299,852 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx382,634,272 - 82,774,000 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0391,233,326 - 91,373,052 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,085,209 - 89,224,609 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,097,068 - 82,236,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,097,068 - 82,236,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0388,799,484 - 88,939,072 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4377,602,718 - 77,742,512 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera378,363,376 - 78,502,825 (-)NCBICelera
Cytogenetic Map3q31NCBI
TSPAN18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381144,726,310 - 44,932,423 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1144,726,465 - 44,932,423 (+)EnsemblGRCh38hg38GRCh38
GRCh371144,748,512 - 44,953,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,837,628 - 44,909,463 (+)NCBINCBI36Build 36hg18NCBI36
Celera1144,932,703 - 45,100,673 (+)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1144,496,710 - 44,664,644 (+)NCBIHuRef
CHM1_11144,785,142 - 44,953,229 (+)NCBICHM1_1
T2T-CHM13v2.01144,883,873 - 45,089,263 (+)NCBIT2T-CHM13v2.0
Tspan18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39293,032,105 - 93,164,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl293,032,105 - 93,164,850 (-)EnsemblGRCm39 Ensembl
GRCm38293,201,760 - 93,334,551 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl293,201,760 - 93,334,505 (-)EnsemblGRCm38mm10GRCm38
MGSCv37293,041,917 - 93,174,644 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36293,002,599 - 93,135,289 (-)NCBIMGSCv36mm8
Celera294,597,454 - 94,729,881 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map251.37NCBI
Tspan18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554222,833,130 - 2,871,460 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554222,833,124 - 2,871,460 (-)NCBIChiLan1.0ChiLan1.0
TSPAN18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2946,940,695 - 47,144,819 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11146,947,103 - 47,148,202 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01144,686,159 - 44,890,196 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11145,180,395 - 45,384,114 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1145,349,629 - 45,384,101 (+)Ensemblpanpan1.1panPan2
TSPAN18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11844,386,676 - 44,539,859 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1844,388,761 - 44,445,847 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1843,116,656 - 43,302,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01845,045,146 - 45,231,055 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1845,045,225 - 45,105,837 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11844,528,315 - 44,714,214 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01844,081,829 - 44,267,706 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01844,815,088 - 45,000,937 (-)NCBIUU_Cfam_GSD_1.0
Tspan18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494721,730,017 - 21,776,978 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365623,843,780 - 3,857,679 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365623,842,035 - 3,968,555 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPAN18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl217,465,633 - 17,634,715 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1217,465,624 - 17,671,737 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2219,000,959 - 19,021,135 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TSPAN18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1120,418,064 - 20,628,756 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl120,419,131 - 20,442,651 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038117,663,040 - 117,866,186 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspan18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247673,362,738 - 3,378,177 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247673,362,738 - 3,459,336 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tspan18
1023 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:342
Count of miRNA genes:198
Interacting mature miRNAs:244
Transcripts:ENSRNOT00000011650
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat

Markers in Region
D3Rat222  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2379,285,268 - 79,285,397 (+)MAPPERmRatBN7.2
Rnor_6.0382,222,060 - 82,222,188NCBIRnor6.0
Rnor_6.0384,243,073 - 84,243,201NCBIRnor6.0
Rnor_5.0390,945,643 - 90,945,771UniSTSRnor5.0
Rnor_5.0388,924,451 - 88,924,579UniSTSRnor5.0
RGSC_v3.4377,727,908 - 77,728,036UniSTSRGSC3.4
RGSC_v3.4377,727,907 - 77,728,035RGDRGSC3.4
RGSC_v3.1377,624,335 - 77,624,463RGD
Celera378,488,221 - 78,488,349UniSTS
SHRSP x BN Map342.7898UniSTS
SHRSP x BN Map342.7898RGD
Cytogenetic Map3q24UniSTS
D5S1969  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2379,181,443 - 79,182,851 (+)MAPPERmRatBN7.2
mRatBN7.239,074,991 - 9,075,594 (+)MAPPERmRatBN7.2
Rnor_6.0382,118,453 - 82,119,922NCBIRnor6.0
Rnor_6.033,702,322 - 3,702,924NCBIRnor6.0
Rnor_5.039,064,115 - 9,064,717UniSTSRnor5.0
Rnor_5.0388,820,870 - 88,822,339UniSTSRnor5.0
Cytogenetic Map3q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 38 17 8 7 8 51 25 33 11
Low 2 5 40 33 12 33 7 10 23 10 8 7
Below cutoff 1 1 1

Sequence


RefSeq Acc Id: ENSRNOT00000011650   ⟹   ENSRNOP00000011650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,161,662 - 79,299,852 (-)Ensembl
Rnor_6.0 Ensembl382,097,068 - 82,236,664 (-)Ensembl
RefSeq Acc Id: NM_001107750   ⟹   NP_001101220
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,615,466 - 99,755,270 (-)NCBI
mRatBN7.2379,160,060 - 79,299,873 (-)NCBI
Rnor_6.0382,097,068 - 82,236,664 (-)NCBI
Rnor_5.0388,799,484 - 88,939,072 (-)NCBI
RGSC_v3.4377,602,718 - 77,742,512 (-)RGD
Celera378,363,376 - 78,502,825 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234574   ⟹   XP_006234636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,615,465 - 99,755,175 (-)NCBI
mRatBN7.2379,161,699 - 79,299,907 (-)NCBI
Rnor_6.0382,097,070 - 82,236,694 (-)NCBI
Rnor_5.0388,799,484 - 88,939,072 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104911   ⟹   XP_038960839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,615,465 - 99,709,223 (-)NCBI
mRatBN7.2379,161,699 - 79,253,815 (-)NCBI
RefSeq Acc Id: XM_039104912   ⟹   XP_038960840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,615,465 - 99,755,175 (-)NCBI
mRatBN7.2379,161,699 - 79,299,907 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101220 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234636 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960839 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960840 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79587 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011650
  ENSRNOP00000011650.5
RefSeq Acc Id: NP_001101220   ⟸   NM_001107750
- UniProtKB: D4A3U2 (UniProtKB/TrEMBL),   A6HNI6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234636   ⟸   XM_006234574
- Peptide Label: isoform X1
- UniProtKB: D4A3U2 (UniProtKB/TrEMBL),   A6HNI6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011650   ⟸   ENSRNOT00000011650
RefSeq Acc Id: XP_038960840   ⟸   XM_039104912
- Peptide Label: isoform X1
- UniProtKB: D4A3U2 (UniProtKB/TrEMBL),   A6HNI6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960839   ⟸   XM_039104911
- Peptide Label: isoform X1
- UniProtKB: D4A3U2 (UniProtKB/TrEMBL),   A6HNI6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3U2-F1-model_v2 AlphaFold D4A3U2 1-248 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692230
Promoter ID:EPDNEW_R2755
Type:multiple initiation site
Name:Tspan18_1
Description:tetraspanin 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0382,236,644 - 82,236,704EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560411 AgrOrtholog
BioCyc Gene G2FUF-48671 BioCyc
Ensembl Genes ENSRNOG00000008758 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011650.6 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/TrEMBL
InterPro Tetraspanin UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/TrEMBL
  Tetraspanin_EC2 UniProtKB/TrEMBL
  Tetraspanin_sub UniProtKB/TrEMBL
KEGG Report rno:311210 UniProtKB/TrEMBL
NCBI Gene 311210 ENTREZGENE
PANTHER PTHR19282 UniProtKB/TrEMBL
  TETRASPANIN-18 UniProtKB/TrEMBL
Pfam Tetraspannin UniProtKB/TrEMBL
PhenoGen Tspan18 PhenoGen
PIRSF Tetraspanin UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/TrEMBL
PROSITE TM4_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008758 RatGTEx
Superfamily-SCOP Tetraspanin UniProtKB/TrEMBL
UniProt A6HNI6 ENTREZGENE, UniProtKB/TrEMBL
  D4A3U2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tspan18  tetraspanin 18   Tspan18_predicted  tetraspanin 18 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Tspan18_predicted  tetraspanin 18 (predicted)  RGD1560411_predicted  similar to Hypothetical protein 6720430O15 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1560411_predicted  similar to Hypothetical protein 6720430O15 (predicted)  LOC311210  similar to Hypothetical protein 6720430O15  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC311210  similar to Hypothetical protein 6720430O15      Symbol and Name status set to provisional 70820 PROVISIONAL