Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of PACSIN3 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PACSIN3 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PACSIN3 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PACSIN3 mRNA | CTD | PMID:27913140 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PACSIN3 mRNA | CTD | PMID:27913140 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PACSIN3 mRNA | CTD | PMID:26290441 and PMID:27913140 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PACSIN3 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-sulfonyldiphenol | affects expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | bisphenol S affects the expression of PACSIN3 protein | CTD | PMID:31945527 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PACSIN3 mRNA | CTD | PMID:24780913 and PMID:30047161 | aflatoxin B1 | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of PACSIN3 mRNA | CTD | PMID:22100608 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PACSIN3 mRNA | CTD | PMID:30047161 | benzo[a]pyrene | multiple interactions | ISO | Pacsin3 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of PACSIN3 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PACSIN3 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | PACSIN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PACSIN3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PACSIN3 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of PACSIN3 mRNA | CTD | PMID:22228805 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PACSIN3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PACSIN3 mRNA | CTD | PMID:35598803 | bisphenol A | affects splicing | ISO | Pacsin3 (Mus musculus) | 6480464 | bisphenol A affects the splicing of PACSIN3 mRNA | CTD | PMID:37894381 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PACSIN3 mRNA | CTD | PMID:32145629 | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of PACSIN3 protein | CTD | PMID:28903499 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of PACSIN3 mRNA | CTD | PMID:19167457 | caffeine | affects phosphorylation | ISO | PACSIN3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of PACSIN3 protein | CTD | PMID:35688186 | cantharidin | decreases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of PACSIN3 mRNA | CTD | PMID:36907384 | CGP 52608 | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PACSIN3 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of PACSIN3 mRNA | CTD | PMID:37019170 | copper atom | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PACSIN3 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PACSIN3 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PACSIN3 mRNA | CTD | PMID:19549813 | coumarin | decreases phosphorylation | ISO | PACSIN3 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of PACSIN3 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PACSIN3 mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PACSIN3 mRNA | CTD | PMID:25562108 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PACSIN3 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PACSIN3 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of PACSIN3 mRNA | CTD | PMID:29803840 | entinostat | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | entinostat results in increased expression of PACSIN3 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PACSIN3 mRNA | CTD | PMID:27188386 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of PACSIN3 mRNA | CTD | PMID:20655511 | ethanol | affects splicing | ISO | Pacsin3 (Mus musculus) | 6480464 | Ethanol affects the splicing of PACSIN3 mRNA | CTD | PMID:30319688 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of PACSIN3 mRNA | CTD | PMID:24136188 | FR900359 | affects phosphorylation | ISO | PACSIN3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of PACSIN3 protein | CTD | PMID:37730182 | hypochlorous acid | increases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Hypochlorous Acid results in increased expression of PACSIN3 mRNA | CTD | PMID:19376150 | ivermectin | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PACSIN3 protein | CTD | PMID:32959892 | lipopolysaccharide | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PACSIN3 mRNA | CTD | PMID:35811015 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of PACSIN3 mRNA | CTD | PMID:30047161 | methylmercury chloride | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PACSIN3 mRNA | CTD | PMID:28001369 | paracetamol | affects expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PACSIN3 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PACSIN3 mRNA | CTD | PMID:33387578 | phenobarbital | affects expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PACSIN3 mRNA | CTD | PMID:19159669 | pirinixic acid | multiple interactions | ISO | Pacsin3 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PACSIN3 mRNA | CTD | PMID:19710929 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PACSIN3 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | PACSIN3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PACSIN3 mRNA | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PACSIN3 mRNA | CTD | PMID:23806026 | styrene | increases expression | EXP | | 6480464 | Styrene results in increased expression of PACSIN3 mRNA | CTD | PMID:17654243 | sulindac | increases expression | EXP | | 6480464 | Sulindac results in increased expression of PACSIN3 mRNA | CTD | PMID:24136188 | sunitinib | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of PACSIN3 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of PACSIN3 mRNA | CTD | PMID:31758290 | testosterone | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Testosterone results in increased expression of PACSIN3 mRNA | CTD | PMID:33359661 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PACSIN3 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | titanium dioxide results in decreased expression of PACSIN3 protein | CTD | PMID:30910687 | trimellitic anhydride | decreases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of PACSIN3 mRNA | CTD | PMID:19042947 | triptonide | decreases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | triptonide results in decreased expression of PACSIN3 mRNA | CTD | PMID:33045310 | tunicamycin | increases expression | ISO | Pacsin3 (Mus musculus) | 6480464 | Tunicamycin results in increased expression of PACSIN3 mRNA | CTD | PMID:17127020 | urethane | decreases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of PACSIN3 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | PACSIN3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PACSIN3 mRNA | CTD | PMID:29154799 | |