Ndufs3 (NADH:ubiquinone oxidoreductase core subunit S3) - Rat Genome Database

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Gene: Ndufs3 (NADH:ubiquinone oxidoreductase core subunit S3) Rattus norvegicus
Analyze
Symbol: Ndufs3
Name: NADH:ubiquinone oxidoreductase core subunit S3
RGD ID: 1309406
Description: Predicted to enable NADH dehydrogenase activity. Predicted to contribute to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in several processes, including mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; and substantia nigra development. Located in mitochondrion. Biomarker of Parkinsonism. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 8. Orthologous to human NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3); PARTICIPATES IN doxorubicin pharmacokinetics pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC295923; NADH dehydrogenase (ubiquinone) Fe-S protein 3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2376,876,646 - 76,883,824 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl376,876,646 - 76,883,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx380,354,354 - 80,361,560 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0388,952,835 - 88,960,041 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0386,804,226 - 86,811,400 (-)NCBIRnor_WKY
Rnor_6.0379,721,686 - 79,728,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,721,694 - 79,728,879 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,430,806 - 86,437,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,256,383 - 75,263,560 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1375,152,762 - 75,159,826 (-)NCBI
Celera376,085,667 - 76,092,843 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats. Akude E, etal., Diabetes. 2011 Jan;60(1):288-97. Epub 2010 Sep 28.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments. Mukherjee S, etal., Alzheimers Dement. 2017 Oct;13(10):1133-1142. doi: 10.1016/j.jalz.2017.01.016. Epub 2017 Feb 24.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
9. Proteomic analysis of expression and protein interactions in a 6-hydroxydopamine-induced rat brain lesion model. Park B, etal., Neurochem Int. 2010 Aug;57(1):16-32. doi: 10.1016/j.neuint.2010.04.005. Epub 2010 Apr 18.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat. Tang Y, etal., Cardiovasc Pathol. 2013 Nov 14. pii: S1054-8807(13)00200-7. doi: 10.1016/j.carpath.2013.11.002.
16. Mitochondrial proteome analysis reveals depression of the Ndufs3 subunit and activity of complex I in diabetic rat brain. Taurino F, etal., J Proteomics. 2012 Apr 18;75(8):2331-41. doi: 10.1016/j.jprot.2012.02.002. Epub 2012 Feb 23.
17. Gene expression profiling in glomeruli of diabetic nephropathy rat. Zhang Q, etal., Exp Biol Med (Maywood). 2012 Aug;237(8):903-11. doi: 10.1258/ebm.2012.012032. Epub 2012 Aug 17.
18. Telmisartan improves kidney function through inhibition of the oxidative phosphorylation pathway in diabetic rats. Zhang Q, etal., J Mol Endocrinol. 2012 Jun 26;49(1):35-46. doi: 10.1530/JME-12-0020. Print 2012 Aug.
Additional References at PubMed
PMID:11112787   PMID:12611891   PMID:12865426   PMID:14651853   PMID:16826196   PMID:17209039   PMID:17634366   PMID:18396137   PMID:18614015   PMID:19837698   PMID:22926577   PMID:24154540  
PMID:30361391   PMID:31536960  


Genomics

Comparative Map Data
Ndufs3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2376,876,646 - 76,883,824 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl376,876,646 - 76,883,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx380,354,354 - 80,361,560 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0388,952,835 - 88,960,041 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0386,804,226 - 86,811,400 (-)NCBIRnor_WKY
Rnor_6.0379,721,686 - 79,728,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,721,694 - 79,728,879 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,430,806 - 86,437,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,256,383 - 75,263,560 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1375,152,762 - 75,159,826 (-)NCBI
Celera376,085,667 - 76,092,843 (-)NCBICelera
Cytogenetic Map3q24NCBI
NDUFS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,579,074 - 47,584,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1147,565,336 - 47,584,562 (+)EnsemblGRCh38hg38GRCh38
GRCh371147,600,626 - 47,606,114 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361147,557,208 - 47,562,690 (+)NCBINCBI36Build 36hg18NCBI36
Build 341147,557,207 - 47,562,689NCBI
Celera1147,743,293 - 47,748,843 (+)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1147,301,639 - 47,307,200 (+)NCBIHuRef
CHM1_11147,599,803 - 47,605,356 (+)NCBICHM1_1
T2T-CHM13v2.01147,739,496 - 47,744,966 (+)NCBIT2T-CHM13v2.0
Ndufs3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39290,724,971 - 90,735,065 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl290,724,978 - 90,735,171 (-)EnsemblGRCm39 Ensembl
GRCm38290,894,627 - 90,904,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl290,894,634 - 90,904,827 (-)EnsemblGRCm38mm10GRCm38
MGSCv37290,734,793 - 90,744,878 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36290,695,475 - 90,705,560 (-)NCBIMGSCv36mm8
Celera292,279,671 - 92,289,201 (-)NCBICelera
Cytogenetic Map2E1NCBI
Ndufs3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955422709,784 - 717,926 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955422713,370 - 717,926 (-)NCBIChiLan1.0ChiLan1.0
NDUFS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11148,078,332 - 48,083,863 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1148,078,332 - 48,083,863 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01147,528,680 - 47,534,206 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NDUFS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11842,069,402 - 42,075,843 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1842,069,398 - 42,076,921 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1840,800,727 - 40,807,169 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01842,725,265 - 42,731,706 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11842,212,502 - 42,219,616 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01841,766,818 - 41,773,261 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01842,496,862 - 42,503,304 (-)NCBIUU_Cfam_GSD_1.0
Ndufs3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494719,556,138 - 19,563,014 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365621,664,293 - 1,674,670 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365621,667,780 - 1,674,670 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl215,031,149 - 15,036,880 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1215,031,147 - 15,036,880 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2216,207,693 - 16,213,425 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,735,040 - 17,740,508 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,733,645 - 17,745,677 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038115,027,358 - 115,033,159 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufs3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247671,237,261 - 1,244,031 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247671,238,953 - 1,243,945 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ndufs3
29 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:48
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000012425
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat

Markers in Region
RH133959  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2376,876,188 - 76,876,369 (+)MAPPERmRatBN7.2
Rnor_6.0379,721,229 - 79,721,409NCBIRnor6.0
Rnor_5.0386,430,349 - 86,430,529UniSTSRnor5.0
RGSC_v3.4375,255,926 - 75,256,106UniSTSRGSC3.4
Celera376,085,210 - 76,085,390UniSTS
Cytogenetic Map3q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012425   ⟹   ENSRNOP00000012425
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl376,876,646 - 76,883,824 (-)Ensembl
Rnor_6.0 Ensembl379,721,694 - 79,728,879 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107192   ⟹   ENSRNOP00000091491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl376,876,654 - 76,883,664 (-)Ensembl
RefSeq Acc Id: NM_001106489   ⟹   NP_001099959
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2376,876,646 - 76,883,824 (-)NCBI
Rnor_6.0379,721,686 - 79,728,863 (-)NCBI
Rnor_5.0386,430,806 - 86,437,983 (-)NCBI
RGSC_v3.4375,256,383 - 75,263,560 (-)RGD
Celera376,085,667 - 76,092,843 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099959 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79487 (Get FASTA)   NCBI Sequence Viewer  
  EDL79488 (Get FASTA)   NCBI Sequence Viewer  
  EDL79489 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001099959   ⟸   NM_001106489
- UniProtKB: D3ZG43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012425   ⟸   ENSRNOT00000012425
RefSeq Acc Id: ENSRNOP00000091491   ⟸   ENSRNOT00000107192
Protein Domains
Complex1_30kDa

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZG43-F1-model_v2 AlphaFold D3ZG43 1-264 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692200
Promoter ID:EPDNEW_R2725
Type:multiple initiation site
Name:Ndufs3_1
Description:NADH:ubiquinone oxidoreductase core subunit S3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0379,728,710 - 79,728,770EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309406 AgrOrtholog
BioCyc Gene G2FUF-48759 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
Ensembl Genes ENSRNOG00000009155 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000012425 ENTREZGENE
  ENSRNOP00000012425.4 UniProtKB/TrEMBL
  ENSRNOP00000091491.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012425 ENTREZGENE
  ENSRNOT00000012425.7 UniProtKB/TrEMBL
  ENSRNOT00000107192.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.460.80 UniProtKB/TrEMBL
InterPro NADH_DH_csu UniProtKB/TrEMBL
  NADH_quin_OxRdtase_su_C/D-like UniProtKB/TrEMBL
  NADH_UbQ_OxRdtase_30kDa_su UniProtKB/TrEMBL
  NADH_UbQ_OxRdtase_CS UniProtKB/TrEMBL
KEGG Report rno:295923 UniProtKB/TrEMBL
NCBI Gene 295923 ENTREZGENE
Pfam Complex1_30kDa UniProtKB/TrEMBL
PhenoGen Ndufs3 PhenoGen
PROSITE COMPLEX1_30K UniProtKB/TrEMBL
Superfamily-SCOP SSF143243 UniProtKB/TrEMBL
TIGRFAMs NuoC_fam UniProtKB/TrEMBL
UniProt A0A8I6ADT5_RAT UniProtKB/TrEMBL
  D3ZG43 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-29 Ndufs3  NADH:ubiquinone oxidoreductase core subunit S3  Ndufs3  NADH dehydrogenase (ubiquinone) Fe-S protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ndufs3  NADH dehydrogenase (ubiquinone) Fe-S protein 3   Ndufs3_predicted  NADH dehydrogenase (ubiquinone) Fe-S protein 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ndufs3_predicted  NADH dehydrogenase (ubiquinone) Fe-S protein 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED