Dusp2 (dual specificity phosphatase 2) - Rat Genome Database

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Gene: Dusp2 (dual specificity phosphatase 2) Rattus norvegicus
Analyze
Symbol: Dusp2
Name: dual specificity phosphatase 2
RGD ID: 1305804
Description: Predicted to enable mitogen-activated protein kinase binding activity and phosphoprotein phosphatase activity. Predicted to be involved in endoderm formation and negative regulation of MAPK cascade. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human DUSP2 (dual specificity phosphatase 2); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dual specificity protein phosphatase 2; LOC311406
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,009,636 - 135,011,821 (+)NCBIGRCr8
mRatBN7.23114,556,325 - 114,558,510 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,556,325 - 114,558,499 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3118,445,557 - 118,447,742 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,041,118 - 127,043,303 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,701,487 - 124,703,672 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,776,925 - 119,779,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,776,925 - 119,779,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,303,199 - 126,305,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,838,605 - 114,840,790 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13114,744,177 - 114,746,352 (+)NCBI
Celera3113,395,499 - 113,397,684 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dieldrin  (ISO)
dimethylarsinic acid  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
etoposide  (ISO)
ferroheme b  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glyphosate  (ISO)
heme b  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
L-methionine  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
melphalan  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylarsonic acid  (ISO)
methylisothiazolinone  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-Nitrosopyrrolidine  (ISO)
omega-6 fatty acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
tebuconazole  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16288922   PMID:24851838  


Genomics

Comparative Map Data
Dusp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,009,636 - 135,011,821 (+)NCBIGRCr8
mRatBN7.23114,556,325 - 114,558,510 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,556,325 - 114,558,499 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3118,445,557 - 118,447,742 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,041,118 - 127,043,303 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,701,487 - 124,703,672 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,776,925 - 119,779,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,776,925 - 119,779,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,303,199 - 126,305,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,838,605 - 114,840,790 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13114,744,177 - 114,746,352 (+)NCBI
Celera3113,395,499 - 113,397,684 (+)NCBICelera
Cytogenetic Map3q36NCBI
DUSP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38296,143,169 - 96,145,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl296,143,169 - 96,145,440 (-)EnsemblGRCh38hg38GRCh38
GRCh37296,808,908 - 96,811,179 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,172,638 - 96,174,906 (-)NCBINCBI36Build 36hg18NCBI36
Build 34296,230,790 - 96,233,053NCBI
Celera291,249,715 - 91,251,986 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef290,770,185 - 90,772,456 (-)NCBIHuRef
CHM1_1296,813,182 - 96,815,453 (-)NCBICHM1_1
T2T-CHM13v2.0296,649,773 - 96,656,541 (-)NCBIT2T-CHM13v2.0
Dusp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,178,079 - 127,180,297 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,178,079 - 127,180,296 (+)EnsemblGRCm39 Ensembl
GRCm382127,336,159 - 127,338,377 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,336,159 - 127,338,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,161,895 - 127,164,113 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,316,151 - 128,318,369 (+)NCBIMGSCv36mm8
MGSCv362127,027,600 - 127,029,818 (+)NCBIMGSCv36mm8
Cytogenetic Map2F1NCBI
cM Map261.93NCBI
Dusp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,735,871 - 3,737,568 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554703,735,224 - 3,737,667 (-)NCBIChiLan1.0ChiLan1.0
DUSP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21232,163,053 - 32,165,336 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A32,165,812 - 32,168,095 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A103,169,874 - 103,172,158 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A97,068,210 - 97,070,505 (-)NCBIpanpan1.1PanPan1.1panPan2
DUSP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11734,586,635 - 34,589,076 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,586,716 - 34,588,453 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1734,356,392 - 34,358,603 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01735,357,957 - 35,360,188 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1735,357,957 - 35,360,187 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11734,487,278 - 34,489,485 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01734,555,607 - 34,557,809 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01734,762,735 - 34,764,961 (+)NCBIUU_Cfam_GSD_1.0
Dusp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,018,673 - 83,020,329 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744271,469 - 273,326 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936744271,619 - 273,272 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUSP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,052,458 - 47,054,810 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1347,052,443 - 47,054,816 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,187,416 - 49,194,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DUSP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114580,686 - 582,939 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14580,694 - 582,910 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041168,001,720 - 168,004,581 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dusp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,258,356 - 2,260,455 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247492,258,317 - 2,260,542 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dusp2
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:73
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000018549
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3102200529115665732Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat

Markers in Region
RH133485  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23114,558,271 - 114,558,451 (+)MAPPERmRatBN7.2
Rnor_6.03119,778,872 - 119,779,051NCBIRnor6.0
Rnor_5.03126,305,146 - 126,305,325UniSTSRnor5.0
RGSC_v3.43114,840,552 - 114,840,731UniSTSRGSC3.4
Celera3113,397,446 - 113,397,625UniSTS
RH 3.4 Map3997.7UniSTS
Cytogenetic Map3q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 12 4 19 4 16 8 1
Low 1 41 32 25 25 6 6 58 27 38 10 6
Below cutoff 13 12 12 2 5 3 2

Sequence


RefSeq Acc Id: ENSRNOT00000018549   ⟹   ENSRNOP00000018549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3114,556,325 - 114,558,499 (+)Ensembl
Rnor_6.0 Ensembl3119,776,925 - 119,779,099 (+)Ensembl
RefSeq Acc Id: NM_001012089   ⟹   NP_001012089
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83135,009,636 - 135,011,821 (+)NCBI
mRatBN7.23114,556,325 - 114,558,510 (+)NCBI
Rnor_6.03119,776,925 - 119,779,110 (+)NCBI
Rnor_5.03126,303,199 - 126,305,384 (+)NCBI
RGSC_v3.43114,838,605 - 114,840,790 (+)RGD
Celera3113,395,499 - 113,397,684 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001012089 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88205 (Get FASTA)   NCBI Sequence Viewer  
  EDL80113 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018549
  ENSRNOP00000018549.5
RefSeq Acc Id: NP_001012089   ⟸   NM_001012089
- UniProtKB: Q5M863 (UniProtKB/TrEMBL),   A6HQ12 (UniProtKB/TrEMBL),   F7F375 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018549   ⟸   ENSRNOT00000018549
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M863-F1-model_v2 AlphaFold Q5M863 1-318 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692403
Promoter ID:EPDNEW_R2928
Type:single initiation site
Name:Dusp2_1
Description:dual specificity phosphatase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03119,776,911 - 119,776,971EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305804 AgrOrtholog
BioCyc Gene G2FUF-47995 BioCyc
Ensembl Genes ENSRNOG00000013862 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018549 ENTREZGENE
  ENSRNOT00000018549.6 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7380627 IMAGE-MGC_LOAD
InterPro Dual-sp/Tyr_phosphatase UniProtKB/TrEMBL
  Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  Dual-sp_phosphatase_subgr_cat UniProtKB/TrEMBL
  MAPK_phosph UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Rhodanese-like UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
KEGG Report rno:311406 UniProtKB/TrEMBL
MGC_CLONE MGC:108907 IMAGE-MGC_LOAD
NCBI Gene 311406 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN PHOSPHATASE UniProtKB/TrEMBL
  DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 UniProtKB/TrEMBL
Pfam DSPc UniProtKB/TrEMBL
  Rhodanese UniProtKB/TrEMBL
PhenoGen Dusp2 PhenoGen
PIRSF MAPK_Ptase UniProtKB/TrEMBL
PRINTS ADSPHPHTASE UniProtKB/TrEMBL
  MAPKPHPHTASE UniProtKB/TrEMBL
PROSITE RHODANESE_3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013862 RatGTEx
SMART DSPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  RHOD UniProtKB/TrEMBL
Superfamily-SCOP Rhodanese-like UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A6HQ12 ENTREZGENE, UniProtKB/TrEMBL
  F7F375 ENTREZGENE, UniProtKB/TrEMBL
  Q5M863 ENTREZGENE
UniProt Secondary Q5M863 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Dusp2  dual specificity phosphatase 2  Dusp2_predicted  dual specificity phosphatase 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dusp2_predicted  dual specificity phosphatase 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED