Dgkz (diacylglycerol kinase zeta) - Rat Genome Database

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Gene: Dgkz (diacylglycerol kinase zeta) Rattus norvegicus
Analyze
Symbol: Dgkz
Name: diacylglycerol kinase zeta
RGD ID: 70929
Description: Enables diacylglycerol kinase activity. Predicted to be involved in several processes, including glycerolipid metabolic process; lipid phosphorylation; and maintenance of postsynaptic density structure. Predicted to act upstream of or within negative regulation of Ras protein signal transduction. Located in nucleus. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human DGKZ (diacylglycerol kinase zeta); PARTICIPATES IN glycerolipid metabolic pathway; glycerophospholipid metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 104 kDa diacylglycerol kinase; DAG kinase zeta; DGK-IV; DGK-zeta; diglyceride kinase zeta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2377,904,149 - 77,946,114 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl377,904,150 - 77,946,099 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx381,379,328 - 81,409,244 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0389,978,358 - 90,008,274 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0387,829,580 - 87,859,521 (-)NCBIRnor_WKY
Rnor_6.0380,844,002 - 80,886,487 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl380,844,005 - 80,875,817 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0387,542,666 - 87,584,698 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4376,312,721 - 76,342,603 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1376,209,092 - 76,238,975 (-)NCBI
Celera377,106,807 - 77,136,681 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus. Goto K and Kondo H, Proc Natl Acad Sci U S A 1996 Oct 1;93(20):11196-201.
4. Gene cloning, sequence, expression and in situ localization of 80 kDa diacylglycerol kinase specific to oligodendrocyte of rat brain. Goto K, etal., Brain Res Mol Brain Res 1992 Nov;16(1-2):75-87.
5. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
6. Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. Kim K, etal., EMBO J. 2009 Apr 22;28(8):1170-9. doi: 10.1038/emboj.2009.44. Epub 2009 Feb 19.
7. Diacylglycerol kinase zeta regulates phosphatidylinositol 4-phosphate 5-kinase Ialpha by a novel mechanism. Luo B, etal., Cell Signal. 2004 Aug;16(8):891-7. doi: 10.1016/j.cellsig.2004.01.010.
8. Gene Data Set MGD Curation, June 12, 2002
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Cellular expression and localization of DGKzeta-interacting NAP1-like proteins in the brain and functional implications under hypoxic stress. Takahashi N, etal., Histochem Cell Biol. 2014 Nov;142(5):461-71. doi: 10.1007/s00418-014-1226-x. Epub 2014 Jun 4.
Additional References at PubMed
PMID:12477932   PMID:14511325   PMID:15542238   PMID:15544348   PMID:15781737   PMID:15894621   PMID:16286473   PMID:16380548   PMID:17664281   PMID:18004883   PMID:19520144   PMID:19744926  
PMID:21183507   PMID:21362459   PMID:21938675   PMID:22234382   PMID:22627129   PMID:23467923   PMID:27739494   PMID:30053369   PMID:34312706  


Genomics

Comparative Map Data
Dgkz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2377,904,149 - 77,946,114 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl377,904,150 - 77,946,099 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx381,379,328 - 81,409,244 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0389,978,358 - 90,008,274 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0387,829,580 - 87,859,521 (-)NCBIRnor_WKY
Rnor_6.0380,844,002 - 80,886,487 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl380,844,005 - 80,875,817 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0387,542,666 - 87,584,698 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4376,312,721 - 76,342,603 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1376,209,092 - 76,238,975 (-)NCBI
Celera377,106,807 - 77,136,681 (-)NCBICelera
Cytogenetic Map3q24NCBI
DGKZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381146,332,926 - 46,380,554 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1146,332,905 - 46,380,554 (+)EnsemblGRCh38hg38GRCh38
GRCh371146,354,476 - 46,402,104 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361146,311,315 - 46,358,680 (+)NCBINCBI36Build 36hg18NCBI36
Build 341146,323,562 - 46,358,680NCBI
Celera1146,502,317 - 46,549,682 (+)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1146,061,412 - 46,109,062 (+)NCBIHuRef
CHM1_11146,352,750 - 46,400,540 (+)NCBICHM1_1
T2T-CHM13v2.01146,489,001 - 46,536,630 (+)NCBIT2T-CHM13v2.0
Dgkz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39291,763,167 - 91,806,788 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl291,763,169 - 91,806,209 (-)EnsemblGRCm39 Ensembl
GRCm38291,932,822 - 91,976,443 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl291,932,824 - 91,975,864 (-)EnsemblGRCm38mm10GRCm38
MGSCv37291,772,979 - 91,803,720 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36291,733,665 - 91,764,438 (-)NCBIMGSCv36mm8
Celera293,323,226 - 93,354,092 (-)NCBICelera
Cytogenetic Map2E1NCBI
Dgkz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554221,657,926 - 1,695,404 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554221,658,237 - 1,687,000 (-)NCBIChiLan1.0ChiLan1.0
DGKZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11146,841,605 - 46,889,763 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1146,841,605 - 46,889,763 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01146,291,592 - 46,339,127 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
DGKZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11843,088,169 - 43,103,820 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1843,088,525 - 43,129,294 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1841,816,433 - 41,857,562 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01843,743,999 - 43,785,151 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1843,744,000 - 43,785,151 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11843,228,986 - 43,270,069 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01842,780,862 - 42,821,933 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01843,514,095 - 43,555,174 (-)NCBIUU_Cfam_GSD_1.0
Dgkz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494720,579,265 - 20,621,717 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365622,690,858 - 2,733,620 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365622,690,907 - 2,733,455 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DGKZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl216,134,048 - 16,176,238 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1216,134,046 - 16,176,043 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2217,480,094 - 17,495,716 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DGKZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,949,360 - 18,997,957 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,948,425 - 18,982,354 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038116,234,046 - 116,283,086 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dgkz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247672,173,272 - 2,210,279 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247672,173,774 - 2,210,304 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dgkz
171 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:256
Count of miRNA genes:168
Interacting mature miRNAs:192
Transcripts:ENSRNOT00000024280
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat

Markers in Region
RH141843  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2377,904,240 - 77,904,422 (+)MAPPERmRatBN7.2
Rnor_6.0380,844,088 - 80,844,269NCBIRnor6.0
Rnor_5.0387,542,756 - 87,542,937UniSTSRnor5.0
RGSC_v3.4376,312,804 - 76,312,985UniSTSRGSC3.4
Celera377,106,890 - 77,107,071UniSTS
Cytogenetic Map3q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 56 41 19 41 8 11 74 35 34 11 8
Low 1 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024280   ⟹   ENSRNOP00000024280
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,904,158 - 77,934,040 (-)Ensembl
Rnor_6.0 Ensembl380,844,005 - 80,873,887 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091265   ⟹   ENSRNOP00000074012
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,904,150 - 77,936,017 (-)Ensembl
Rnor_6.0 Ensembl380,844,033 - 80,875,817 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095998   ⟹   ENSRNOP00000087400
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,904,150 - 77,921,396 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112973   ⟹   ENSRNOP00000090177
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,904,158 - 77,934,040 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117598   ⟹   ENSRNOP00000097565
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,904,150 - 77,946,099 (-)Ensembl
RefSeq Acc Id: NM_031143   ⟹   NP_112405
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,904,149 - 77,934,040 (-)NCBI
Rnor_6.0380,844,005 - 80,873,887 (-)NCBI
Rnor_5.0387,542,666 - 87,584,698 (-)NCBI
RGSC_v3.4376,312,721 - 76,342,603 (-)RGD
Celera377,106,807 - 77,136,681 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234594   ⟹   XP_006234656
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,904,157 - 77,921,306 (-)NCBI
Rnor_6.0380,844,002 - 80,861,262 (-)NCBI
Rnor_5.0387,542,666 - 87,584,698 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234596   ⟹   XP_006234658
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,904,151 - 77,936,017 (-)NCBI
Rnor_6.0380,844,002 - 80,875,863 (-)NCBI
Rnor_5.0387,542,666 - 87,584,698 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592062   ⟹   XP_017447551
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,904,151 - 77,946,114 (-)NCBI
Rnor_6.0380,844,002 - 80,886,487 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105924   ⟹   XP_038961852
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,905,553 - 77,918,115 (-)NCBI
RefSeq Acc Id: XM_039105926   ⟹   XP_038961854
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,904,151 - 77,935,942 (-)NCBI
RefSeq Acc Id: XR_005501992
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,910,042 - 77,918,119 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_112405   ⟸   NM_031143
- UniProtKB: O08560 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006234658   ⟸   XM_006234596
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K707 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234656   ⟸   XM_006234594
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A444 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447551   ⟸   XM_017592062
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GM44 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024280   ⟸   ENSRNOT00000024280
RefSeq Acc Id: ENSRNOP00000074012   ⟸   ENSRNOT00000091265
RefSeq Acc Id: XP_038961854   ⟸   XM_039105926
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038961852   ⟸   XM_039105924
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000097565   ⟸   ENSRNOT00000117598
RefSeq Acc Id: ENSRNOP00000087400   ⟸   ENSRNOT00000095998
RefSeq Acc Id: ENSRNOP00000090177   ⟸   ENSRNOT00000112973
Protein Domains
DAGKc

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08560-F1-model_v2 AlphaFold O08560 1-929 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692222
Promoter ID:EPDNEW_R2745
Type:multiple initiation site
Name:Dgkz_1
Description:diacylglycerol kinase zeta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0380,873,894 - 80,873,954EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70929 AgrOrtholog
BioCyc Gene G2FUF-48716 BioCyc
Ensembl Genes ENSRNOG00000017737 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000024280 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000074012 ENTREZGENE
  ENSRNOP00000074012.2 UniProtKB/TrEMBL
  ENSRNOP00000087400 ENTREZGENE
  ENSRNOP00000087400.1 UniProtKB/TrEMBL
  ENSRNOP00000090177.1 UniProtKB/TrEMBL
  ENSRNOP00000097565 ENTREZGENE
  ENSRNOP00000097565.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024280 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000091265 ENTREZGENE
  ENSRNOT00000091265.2 UniProtKB/TrEMBL
  ENSRNOT00000095998 ENTREZGENE
  ENSRNOT00000095998.1 UniProtKB/TrEMBL
  ENSRNOT00000112973.1 UniProtKB/TrEMBL
  ENSRNOT00000117598 ENTREZGENE
  ENSRNOT00000117598.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-NAD_kinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DGK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Diacylglycerol_kin_accessory UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Diacylglycerol_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD/diacylglycerol_kinase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81821 UniProtKB/Swiss-Prot
NCBI Gene 81821 ENTREZGENE
PANTHER PTHR11255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGK_acc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGK_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dgkz PhenoGen
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGKa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF111331 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K707 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A444 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMI5_RAT UniProtKB/TrEMBL
  A0A8I6GM44 ENTREZGENE, UniProtKB/TrEMBL
  DGKZ_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Dgkz  diacylglycerol kinase zeta      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference