Pdia3 (protein disulfide isomerase family A, member 3) - Rat Genome Database

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Gene: Pdia3 (protein disulfide isomerase family A, member 3) Rattus norvegicus
Analyze
Symbol: Pdia3
Name: protein disulfide isomerase family A, member 3
RGD ID: 68430
Description: Exhibits MHC class I protein binding activity; peptidase activity; and protein-disulfide reductase (glutathione) activity. Involved in several processes, including cellular response to nonylphenol; response to benzene; and response to ischemia. Localizes to several cellular components, including acrosomal vesicle; endoplasmic reticulum; and mitochondrial intermembrane space. Used to study autoimmune hepatitis and irritable bowel syndrome. Biomarker of asphyxia neonatorum; irritable bowel syndrome; liver cirrhosis; post-traumatic stress disorder; and pulmonary hypertension. Human ortholog(s) of this gene implicated in autoimmune hepatitis. Orthologous to human PDIA3 (protein disulfide isomerase family A member 3); PARTICIPATES IN antigen processing and presentation pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; disulfide isomerase ER-60; endoplasmic reticulum resident protein 57; endoplasmic reticulum resident protein 60; ER protein 57; ER protein 60; ER-60 protease; ER60; ERp57; ERp60; glucose regulated protein, 58 kDa; Grp58; HIP-70; oxidoreductase ERp57; p58; protein disulfide isomerase associated 3; protein disulfide-isomerase A3; Q-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23108,388,189 - 108,412,013 (+)NCBI
Rnor_6.0 Ensembl3113,376,983 - 113,400,707 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03113,376,983 - 113,400,707 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03119,916,772 - 119,940,826 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43108,216,414 - 108,240,138 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13108,117,203 - 108,140,928 (+)NCBI
Celera3107,289,603 - 107,313,229 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,5-hexanedione  (EXP)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
aldehydo-D-glucose  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
Azaspiracid  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
Brodifacoum  (EXP)
bromobenzene  (EXP)
cadmium dichloride  (EXP,ISO)
calcidiol  (EXP)
carbon nanotube  (ISO)
choline  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cocaine  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (EXP)
D-glucose  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (EXP)
dopamine  (ISO)
doxorubicin  (EXP)
endosulfan  (EXP)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP)
flavonoids  (EXP)
folic acid  (EXP)
furan  (EXP)
genistein  (EXP)
glucose  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
iodide salt  (EXP)
isoflavones  (EXP)
kojic acid  (EXP)
L-ascorbic acid  (ISO)
L-ethionine  (EXP)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(II) chloride  (ISO)
limonene  (EXP)
lithium atom  (EXP)
lithium hydride  (EXP)
lovastatin  (ISO)
methamphetamine  (EXP)
microcystin  (EXP)
microcystin RR  (ISO)
Monobutylphthalate  (ISO)
N-hydroxy-PhIP  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosomorpholine  (EXP)
naphthalene  (ISO)
Nonylphenol  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
oxidopamine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
procymidone  (EXP)
progesterone  (ISO)
Propiverine  (EXP)
pyrogallol  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
sarin  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
T-2 toxin  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (EXP)
vinclozolin  (EXP)
vorinostat  (ISO)
warfarin  (ISO)
zinc atom  (ISO)
zinc oxide  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Antoniou AN, etal., EMBO J. 2002 Jun 3;21(11):2655-63.
2. Aroor AR, etal., Proteome Sci. 2012 Apr 30;10(1):29. doi: 10.1186/1477-5956-10-29.
3. Bennett CF, etal., Nature 1988 Jul 21;334(6179):268-70.
4. Chen G, etal., Mol Biol Rep. 2012 May;39(5):5233-8. doi: 10.1007/s11033-011-1321-1. Epub 2011 Dec 27.
5. Ding Y, etal., Zhonghua Yi Xue Za Zhi. 2010 Mar 2;90(8):564-9.
6. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Gouraud SS, etal., Endocrinology. 2007 Jul;148(7):3041-52. Epub 2007 Apr 5.
8. Hetz C, etal., J Neurosci. 2005 Mar 16;25(11):2793-802.
9. Jansen G, etal., Mol Cell Proteomics. 2012 Sep;11(9):710-23. doi: 10.1074/mcp.M111.016550. Epub 2012 Jun 4.
10. Kita K, etal., FEBS Lett. 2006 Jan 9;580(1):199-205. Epub 2005 Dec 9.
11. Kitzmueller E, etal., Neurochem Res. 2004 Sep;29(9):1767-77.
12. Koen YM and Hanzlik RP, Chem Res Toxicol. 2002 May;15(5):699-706.
13. Komurasaki R, etal., Drug Metab Pharmacokinet. 2010;25(1):84-92.
14. MGD data from the GO Consortium
15. Morrice NA and Powis SJ, Curr Biol. 1998 Jun 4;8(12):713-6.
16. Ohata Y, etal., Histol Histopathol. 2013 Jul;28(7):893-902. Epub 2013 Jan 10.
17. Ozaki T, etal., Biochim Biophys Acta. 2008 Oct;1783(10):1955-63. doi: 10.1016/j.bbamcr.2008.05.011. Epub 2008 May 24.
18. Pipeline to import KEGG annotations from KEGG into RGD
19. RGD automated data pipeline
20. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. RGD automated import pipeline for gene-chemical interactions
22. Rohe B, etal., Steroids. 2005 May-Jun;70(5-7):458-63. Epub 2005 Apr 1.
23. Rufer E, etal., J Immunol. 2007 Nov 1;179(9):5717-27.
24. Sakai J, etal., Proteomics. 2003 Jul;3(7):1318-24.
25. Satoh M, etal., Cell Stress Chaperones. 2005 Autumn;10(3):211-20.
26. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
27. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
28. Urade R and Kito M, FEBS Lett. 1992 Nov 2;312(1):83-6.
29. Wang J, etal., J Proteome Res. 2011 Apr 1;10(4):1621-31. Epub 2011 Feb 22.
30. Wu J, etal., Chem Res Toxicol. 2009 Apr;22(4):668-75. doi: 10.1021/tx800406z.
31. Wyse B, etal., Am J Physiol Renal Physiol 2002 Mar;282(3):F424-30.
32. Xu D, etal., Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L44-51. doi: 10.1152/ajplung.90626.2008. Epub 2009 May 1.
33. Yu B, etal., BMC Neurosci. 2014 Oct 21;15:115. doi: 10.1186/s12868-014-0115-5.
34. Zhao Q, etal., Sci China Life Sci. 2014 Mar;57(3):303-14. doi: 10.1007/s11427-014-4619-0. Epub 2014 Feb 21.
35. Zhao XJ, etal., Reprod Domest Anim. 2013 Feb;48(1):59-63. doi: 10.1111/j.1439-0531.2012.02024.x. Epub 2012 Apr 2.
36. Zhuang ZM, etal., Int J Clin Exp Med. 2015 May 15;8(5):6866-77. eCollection 2015.
Additional References at PubMed
PMID:1321829   PMID:1650195   PMID:1657921   PMID:2181662   PMID:9399589   PMID:9493907   PMID:10464281   PMID:13678524   PMID:15489334   PMID:15858817   PMID:15862830   PMID:16260597  
PMID:16516209   PMID:16677074   PMID:16905107   PMID:17154719   PMID:17634366   PMID:18765931   PMID:19199708   PMID:19995400   PMID:20109102   PMID:20130111   PMID:20387083   PMID:21263072  
PMID:21423176   PMID:21630459   PMID:21734266   PMID:21976707   PMID:22658674   PMID:23106098   PMID:23226417   PMID:23376485   PMID:23826168   PMID:24415168   PMID:25241190   PMID:26724776  
PMID:28707894   PMID:29104478   PMID:29581031   PMID:31176989  


Genomics

Comparative Map Data
Pdia3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23108,388,189 - 108,412,013 (+)NCBI
Rnor_6.0 Ensembl3113,376,983 - 113,400,707 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03113,376,983 - 113,400,707 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03119,916,772 - 119,940,826 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43108,216,414 - 108,240,138 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13108,117,203 - 108,140,928 (+)NCBI
Celera3107,289,603 - 107,313,229 (+)NCBICelera
Cytogenetic Map3q35NCBI
PDIA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1543,746,410 - 43,773,278 (+)EnsemblGRCh38hg38GRCh38
GRCh381543,746,438 - 43,773,278 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371544,038,636 - 44,065,476 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361541,825,882 - 41,852,096 (+)NCBINCBI36hg18NCBI36
Celera1520,928,053 - 20,954,266 (+)NCBI
Cytogenetic Map15q15.3NCBI
HuRef1520,861,356 - 20,887,666 (+)NCBIHuRef
CHM1_11544,156,851 - 44,183,060 (+)NCBICHM1_1
Pdia3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392121,244,383 - 121,269,168 (+)NCBIGRCm39mm39
GRCm39 Ensembl2121,244,256 - 121,269,168 (+)Ensembl
GRCm382121,413,902 - 121,438,687 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2121,413,775 - 121,438,687 (+)EnsemblGRCm38mm10GRCm38
MGSCv372121,239,638 - 121,264,423 (+)NCBIGRCm37mm9NCBIm37
MGSCv362121,105,401 - 121,129,421 (+)NCBImm8
Celera2122,564,601 - 122,589,381 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.38NCBI
Pdia3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541610,198,099 - 10,220,792 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541610,197,957 - 10,221,104 (+)NCBIChiLan1.0ChiLan1.0
PDIA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11540,794,144 - 40,821,615 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1540,794,144 - 40,821,763 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01522,706,520 - 22,731,672 (+)NCBIMhudiblu_PPA_v0panPan3
PDIA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13010,487,926 - 10,513,437 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3010,487,921 - 10,513,397 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3010,546,317 - 10,571,800 (+)NCBI
ROS_Cfam_1.03010,624,436 - 10,649,938 (+)NCBI
UMICH_Zoey_3.13010,533,603 - 10,559,083 (+)NCBI
UNSW_CanFamBas_1.03010,655,339 - 10,680,999 (+)NCBI
UU_Cfam_GSD_1.03010,775,223 - 10,800,728 (+)NCBI
Pdia3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864088,961,177 - 88,986,202 (+)NCBI
SpeTri2.0NW_0049364716,809,181 - 6,834,189 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDIA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1127,785,772 - 127,814,196 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11127,786,174 - 127,814,096 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21142,615,686 - 142,643,747 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDIA3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12639,273,982 - 39,300,170 (-)NCBI
ChlSab1.1 Ensembl2639,272,997 - 39,349,966 (-)Ensembl
Pdia3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480410,754,978 - 10,784,641 (+)NCBI

Position Markers
RH131986  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23108,412,652 - 108,412,850 (+)MAPPER
Rnor_6.03113,401,350 - 113,401,547NCBIRnor6.0
Rnor_5.03119,941,469 - 119,941,666UniSTSRnor5.0
RGSC_v3.43108,240,781 - 108,240,978UniSTSRGSC3.4
Celera3107,313,872 - 107,314,069UniSTS
RH 3.4 Map3953.6UniSTS
Cytogenetic Map3q35UniSTS
BE107553  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23108,407,474 - 108,407,641 (+)MAPPER
Rnor_6.03113,396,172 - 113,396,338NCBIRnor6.0
Rnor_5.03119,936,291 - 119,936,457UniSTSRnor5.0
RGSC_v3.43108,235,603 - 108,235,769UniSTSRGSC3.4
Celera3107,308,692 - 107,308,858UniSTS
RH 3.4 Map3954.5UniSTS
Cytogenetic Map3q35UniSTS
RH138056  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23108,390,715 - 108,390,871 (+)MAPPER
mRatBN7.2456,924,637 - 56,924,731 (+)MAPPER
Rnor_6.03113,379,415 - 113,379,570NCBIRnor6.0
Rnor_5.03119,919,204 - 119,919,648UniSTSRnor5.0
Rnor_5.03119,919,204 - 119,919,359UniSTSRnor5.0
RGSC_v3.43108,218,846 - 108,219,001UniSTSRGSC3.4
Celera3107,292,035 - 107,292,190UniSTS
RH 3.4 Map3947.6UniSTS
Cytogenetic Map3q35UniSTS
Grp58  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23108,411,882 - 108,412,007 (+)MAPPER
Rnor_6.03113,400,580 - 113,400,704NCBIRnor6.0
Rnor_5.03119,940,699 - 119,940,823UniSTSRnor5.0
RGSC_v3.43108,240,011 - 108,240,135UniSTSRGSC3.4
Celera3107,313,102 - 107,313,226UniSTS
Cytogenetic Map3q35UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)330114912123700444Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)330846101172879276Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)339248391140271184Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)343295930163640485Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)343295930163640485Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)345406058127023997Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)345406058177699992Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)348561928155263151Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)348562146115249962Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)348562146115249962Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)351821836124513579Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)351822008120917851Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)354630948119830094Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)354630948119830094Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)354630948119830094Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)358204463170534769Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)361241033165369047Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)362922868127023997Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)366711607119830094Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)366711607119830094Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)372672290127023997Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)372973445127023997Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)378700444123700444Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)381136227154416635Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)383817637119509260Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)388910015133910015Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)394788365139788365Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)397009185142009185Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)399465522168732722Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3100730984119830094Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3101058963146058963Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3102152812155263151Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3102466149147466149Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)3103141814176418101Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)3103141814176418101Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3103141814176418101Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3103141944170934860Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3106900427119830094Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:404
Count of miRNA genes:229
Interacting mature miRNAs:270
Transcripts:ENSRNOT00000020478
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 11 6 6 2 1
Medium 3 43 51 35 19 35 8 11 74 33 40 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000020478   ⟹   ENSRNOP00000020478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3113,376,983 - 113,400,707 (+)Ensembl
RefSeq Acc Id: NM_017319   ⟹   NP_059015
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23108,388,189 - 108,412,013 (+)NCBI
Rnor_6.03113,376,983 - 113,400,707 (+)NCBI
Rnor_5.03119,916,772 - 119,940,826 (+)NCBI
RGSC_v3.43108,216,414 - 108,240,138 (+)RGD
Celera3107,289,603 - 107,313,229 (+)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_059015   ⟸   NM_017319
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: ENSRNOP00000020478   ⟸   ENSRNOT00000020478
Protein Domains
Thioredoxin

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692356
Promoter ID:EPDNEW_R2881
Type:multiple initiation site
Name:Pdia3_1
Description:protein disulfide isomerase family A, member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03113,376,951 - 113,377,011EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68430 AgrOrtholog
Ensembl Genes ENSRNOG00000015018 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000020478 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020478 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5621329 IMAGE-MGC_LOAD
InterPro Disulphide_isomerase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDIA3_PDI_b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_disulphide_isomerase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29468 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72503 IMAGE-MGC_LOAD
NCBI Gene 29468 ENTREZGENE
Pfam Thioredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pdia3 PhenoGen
PROSITE THIOREDOXIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217371
TIGRFAMs ER_PDI_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  pdi_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0H2UHM5_RAT UniProtKB/TrEMBL
  P11598 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-10 Pdia3  protein disulfide isomerase family A, member 3  Pdia3  protein disulfide isomerase associated 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Pdia3  protein disulfide isomerase associated 3      Symbol and Name updated 1299863 APPROVED
2002-06-10 Grp58  glucose regulated protein, 58 kDa      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process increases activity of the thiazide-sensitive Na-Cl cotransporter 632898