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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68430
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdia3
Name: protein disulfide isomerase family A, member 3
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdia3multiple interactionsEXP 6480464CTD[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of PDIA3 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PDIA3 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PDIA3 mRNAPMID:14656948 PMID:16158176 PMID:18544905
Pdia3multiple interactionsISOPdia3 (Mus musculus)6480464CTD[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of PDIA3 proteinPMID:23457121
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