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Gene: Rad51 (RAD51 recombinase) Rattus norvegicus
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Symbol: Rad51
Name: RAD51 recombinase
Description: Predicted to have several functions, including ATP binding activity; DNA binding activity; and DNA polymerase binding activity. Involved in several processes, including cellular response to cisplatin; cellular response to gamma radiation; and response to X-ray. Localizes to the nucleus. Used to study cardiomyopathy and hypertension. Biomarker of pancreatic cancer. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group R; breast cancer; congenital mirror movement disorder; and ovarian cancer. Orthologous to human RAD51 (RAD51 recombinase); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ceramide signaling pathway; pancreatic cancer pathway; INTERACTS WITH (-)-demecolcine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA repair protein RAD51 homolog 1; LOC499870; RAD51 homolog; RAD51 homolog (RecA homolog, E. coli); RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae); RAD51 homolog (S. cerevisiae); RGD1563603; similar to DNA repair protein RAD51 homolog 1
Orthologs:
Homo sapiens (human) : RAD51 (RAD51 recombinase)  HGNC  Alliance
Mus musculus (house mouse) : Rad51 (RAD51 recombinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rad51 (RAD51 recombinase)
Pan paniscus (bonobo/pygmy chimpanzee) : RAD51 (RAD51 recombinase)
Canis lupus familiaris (dog) : RAD51 (RAD51 recombinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rad51 (RAD51 recombinase)
Sus scrofa (pig) : RAD51 (RAD51 recombinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03110,918,240 - 110,942,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03117,468,402 - 117,493,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,625,265 - 105,650,392 (+)NCBIRGSC3.4rn4RGSC3.4
Celera3105,013,953 - 105,038,371 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rad51
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563603
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.