Fmn1 (formin 1) - Rat Genome Database

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Gene: Fmn1 (formin 1) Rattus norvegicus
Analyze
Symbol: Fmn1
Name: formin 1
RGD ID: 1306349
Description: Predicted to enable SH3 domain binding activity. Predicted to be involved in actin nucleation. Predicted to act upstream of or within several processes, including limb morphogenesis; positive regulation of cellular component organization; and ureteric bud invasion. Predicted to be located in cytoplasm and nucleus. Orthologous to human FMN1 (formin 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; atrazine; azoxystrobin.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: formin-1; LOC102551877; LOC296053; LOC296512; LOC687921; mRNA turnover protein 4 homolog; RGD1306349; RGD1310100; similar to formin ; similar to formin, isoform IV; similar to Formin-1 isoform IV (Limb deformity protein)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83120,555,445 - 120,939,978 (+)NCBIGRCr8
mRatBN7.23100,101,103 - 100,485,652 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3100,134,549 - 100,479,220 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.03104,783,093 - 105,170,761 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03111,402,075 - 111,748,675 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4399,298,261 - 99,564,034 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1399,093,741 - 99,460,041 (+)NCBI
Celera399,081,027 - 99,451,618 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count. Chen G, etal., Addict Biol. 2017 Nov;22(6):1475-1485. doi: 10.1111/adb.12402. Epub 2016 May 5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2997621   PMID:7517224   PMID:8438166   PMID:8798555   PMID:9234242   PMID:14647292   PMID:16480715   PMID:17554679   PMID:18560567   PMID:21818269   PMID:22427691   PMID:25901598  
PMID:27145014  


Genomics

Comparative Map Data
Fmn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83120,555,445 - 120,939,978 (+)NCBIGRCr8
mRatBN7.23100,101,103 - 100,485,652 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3100,134,549 - 100,479,220 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.03104,783,093 - 105,170,761 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03111,402,075 - 111,748,675 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4399,298,261 - 99,564,034 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1399,093,741 - 99,460,041 (+)NCBI
Celera399,081,027 - 99,451,618 (+)NCBICelera
Cytogenetic Map3q35NCBI
FMN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381532,765,544 - 33,194,714 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1532,765,544 - 33,194,714 (-)EnsemblGRCh38hg38GRCh38
GRCh371533,057,745 - 33,486,915 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361530,853,637 - 31,147,377 (-)NCBINCBI36Build 36hg18NCBI36
Celera159,859,583 - 10,161,753 (-)NCBICelera
Cytogenetic Map15q13.3NCBI
HuRef159,919,586 - 10,348,532 (-)NCBIHuRef
CHM1_11533,175,802 - 33,604,909 (-)NCBICHM1_1
T2T-CHM13v2.01530,562,099 - 30,991,198 (-)NCBIT2T-CHM13v2.0
Fmn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392113,158,029 - 113,547,113 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2113,158,081 - 113,547,112 (+)EnsemblGRCm39 Ensembl
GRCm382113,327,664 - 113,716,768 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2113,327,736 - 113,716,767 (+)EnsemblGRCm38mm10GRCm38
MGSCv372113,167,893 - 113,556,924 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362113,128,621 - 113,510,694 (+)NCBIMGSCv36mm8
Celera2114,475,948 - 114,857,068 (+)NCBICelera
Cytogenetic Map2E4NCBI
cM Map257.3NCBI
Fmn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554161,365,765 - 1,774,027 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554161,365,797 - 1,774,025 (+)NCBIChiLan1.0ChiLan1.0
FMN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21621,540,304 - 21,971,453 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11526,261,987 - 26,693,020 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01511,271,794 - 11,698,539 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11530,105,345 - 30,534,051 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1530,114,113 - 30,495,909 (-)Ensemblpanpan1.1panPan2
FMN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1301,782,726 - 2,215,449 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl301,815,512 - 2,184,909 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha301,831,514 - 2,265,024 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0301,887,585 - 2,328,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl301,886,557 - 2,306,834 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1301,830,799 - 2,264,355 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0301,930,068 - 2,363,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0302,058,309 - 2,491,979 (+)NCBIUU_Cfam_GSD_1.0
Fmn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864080,312,906 - 80,727,325 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366731,432,927 - 1,719,966 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366731,424,513 - 1,838,277 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FMN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1136,704,090 - 137,065,258 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11136,696,353 - 137,163,532 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21153,217,402 - 153,269,191 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FMN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12649,700,309 - 50,117,799 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2649,734,553 - 49,996,405 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604890,768,699 - 91,187,937 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fmn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248041,155,071 - 1,558,145 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248041,124,322 - 1,558,781 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fmn1
2098 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:69
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000041910, ENSRNOT00000042103
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)396127817102200699Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat

Markers in Region
stSG622307  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera399,437,785 - 99,438,735UniSTS
Cytogenetic Map3q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 11 1
Low 3 16 24 8 19 8 8 9 27 35 30 10 8
Below cutoff 27 27 27 27 2 41

Sequence


RefSeq Acc Id: ENSRNOT00000041910   ⟹   ENSRNOP00000050868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3100,205,121 - 100,404,210 (+)Ensembl
Rnor_6.0 Ensembl3104,899,682 - 105,086,436 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000042103   ⟹   ENSRNOP00000042712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3100,134,549 - 100,479,220 (+)Ensembl
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000044625   ⟹   ENSRNOP00000047506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3100,134,821 - 100,479,220 (+)Ensembl
Rnor_6.0 Ensembl3104,816,987 - 105,086,436 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098989   ⟹   ENSRNOP00000094328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3100,205,121 - 100,479,220 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114830   ⟹   ENSRNOP00000091414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3100,183,836 - 100,479,220 (+)Ensembl
RefSeq Acc Id: XM_039106466   ⟹   XP_038962394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,447 - 120,939,978 (+)NCBI
mRatBN7.23100,101,103 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106467   ⟹   XP_038962395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,939,978 (+)NCBI
mRatBN7.23100,101,109 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106468   ⟹   XP_038962396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,576 - 120,939,978 (+)NCBI
mRatBN7.23100,101,382 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106470   ⟹   XP_038962398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,671,429 - 120,939,978 (+)NCBI
mRatBN7.23100,217,053 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106472   ⟹   XP_038962400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,647,575 - 120,939,978 (+)NCBI
mRatBN7.23100,196,233 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_039106474   ⟹   XP_038962402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,721,410 - 120,939,978 (+)NCBI
mRatBN7.23100,267,076 - 100,485,652 (+)NCBI
RefSeq Acc Id: XM_063285289   ⟹   XP_063141359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,939,978 (+)NCBI
RefSeq Acc Id: XM_063285290   ⟹   XP_063141360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,939,978 (+)NCBI
RefSeq Acc Id: XM_063285291   ⟹   XP_063141361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,476 - 120,939,978 (+)NCBI
RefSeq Acc Id: XM_063285292   ⟹   XP_063141362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,672,613 (+)NCBI
RefSeq Acc Id: XM_063285293   ⟹   XP_063141363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83120,555,445 - 120,645,466 (+)NCBI
RefSeq Acc Id: ENSRNOP00000050868   ⟸   ENSRNOT00000041910
RefSeq Acc Id: ENSRNOP00000047506   ⟸   ENSRNOT00000044625
RefSeq Acc Id: ENSRNOP00000042712   ⟸   ENSRNOT00000042103
RefSeq Acc Id: XP_038962394   ⟸   XM_039106466
- Peptide Label: isoform X1
- UniProtKB: D4A4Y9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962395   ⟸   XM_039106467
- Peptide Label: isoform X1
- UniProtKB: D4A4Y9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962396   ⟸   XM_039106468
- Peptide Label: isoform X1
- UniProtKB: D4A4Y9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962400   ⟸   XM_039106472
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GJL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962398   ⟸   XM_039106470
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AHH7 (UniProtKB/TrEMBL),   D3ZBI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962402   ⟸   XM_039106474
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000091414   ⟸   ENSRNOT00000114830
RefSeq Acc Id: ENSRNOP00000094328   ⟸   ENSRNOT00000098989
RefSeq Acc Id: XP_063141360   ⟸   XM_063285290
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063141359   ⟸   XM_063285289
- Peptide Label: isoform X2
- UniProtKB: D4A4Y9 (UniProtKB/TrEMBL),   D4A7C2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141362   ⟸   XM_063285292
- Peptide Label: isoform X6
- UniProtKB: A6HP62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141363   ⟸   XM_063285293
- Peptide Label: isoform X7
- UniProtKB: A6HP62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141361   ⟸   XM_063285291
- Peptide Label: isoform X4
Protein Domains
FH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4Y9-F1-model_v2 AlphaFold D4A4Y9 1-1366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306349 AgrOrtholog
BioCyc Gene G2FUF-48365 BioCyc
Ensembl Genes ENSRNOG00000031760 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041910.6 UniProtKB/TrEMBL
  ENSRNOT00000042103.5 UniProtKB/TrEMBL
  ENSRNOT00000044625.6 UniProtKB/TrEMBL
  ENSRNOT00000098989.1 UniProtKB/TrEMBL
  ENSRNOT00000114830.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.2220 UniProtKB/TrEMBL
InterPro FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  Formin_Cappuccino_subfam UniProtKB/TrEMBL
NCBI Gene 296512 ENTREZGENE
PANTHER FORMIN UniProtKB/TrEMBL
  FORMIN-1 UniProtKB/TrEMBL
Pfam FH2 UniProtKB/TrEMBL
PhenoGen Fmn1 PhenoGen
PRINTS FORMIN UniProtKB/TrEMBL
PROSITE FH2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031760 RatGTEx
SMART FH2 UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
UniProt A0A8I6AHH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJL6 ENTREZGENE, UniProtKB/TrEMBL
  A6HP62 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBI5 ENTREZGENE, UniProtKB/TrEMBL
  D4A4Y9 ENTREZGENE, UniProtKB/TrEMBL
  D4A7C2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Fmn1  formin 1  LOC102551877  mRNA turnover protein 4 homolog  Data merged from RGD:7679496 737654 PROVISIONAL
2013-12-18 LOC102551877  mRNA turnover protein 4 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-06-16 Fmn1  formin 1  RGD1306349  similar to formin   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-15 RGD1306349  similar to formin   LOC687921  similar to Formin-1 isoform IV (Limb deformity protein)  Data merged from RGD:1594927 737654 PROVISIONAL
2009-06-15 RGD1306349  similar to formin   RGD1310100  similar to formin, isoform IV   Data merged from RGD:1310100 1643240 APPROVED
2008-04-30 RGD1310100  similar to formin, isoform IV   RGD1310100_predicted  similar to formin, isoform IV (predicted)  'predicted' is removed 2292626 APPROVED
2008-04-30 RGD1306349  similar to formin   RGD1306349_predicted  similar to formin (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC687921  similar to Formin-1 isoform IV (Limb deformity protein)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1306349_predicted  similar to formin (predicted)  LOC296512_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-20 RGD1310100_predicted  similar to formin, isoform IV (predicted)  LOC296053_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296512_predicted  similar to formin (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 LOC296053_predicted  similar to formin, isoform IV (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL