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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Spinocerebellar Ataxias | | ISO | RGD:1347811 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:18037885 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Spinocerebellar Ataxias | | ISO | RGD:1347811 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:18037885 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
3. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
7. | TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation. | Watanabe T, etal., J Cell Biol. 2015 Aug 31;210(5):737-51. doi: 10.1083/jcb.201412075. |
PMID:11257498 | PMID:21548880 | PMID:22664934 | PMID:23141541 | PMID:24469809 |
Ttbk2 (Rattus norvegicus - Norway rat) |
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TTBK2 (Homo sapiens - human) |
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Ttbk2 (Mus musculus - house mouse) |
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Ttbk2 (Chinchilla lanigera - long-tailed chinchilla) |
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TTBK2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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TTBK2 (Canis lupus familiaris - dog) |
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Ttbk2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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TTBK2 (Sus scrofa - pig) |
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TTBK2 (Chlorocebus sabaeus - green monkey) |
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Ttbk2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Ttbk2
399 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
AI326283 |
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RH134184 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 2 | 15 | 2 | 9 | 2 | 74 | 16 | 31 | 8 | ||||
Low | 3 | 41 | 40 | 37 | 10 | 37 | 8 | 11 | 19 | 10 | 3 | 8 | |
Below cutoff | 2 | 2 | 2 |
RefSeq Transcripts | NM_001107766 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
NM_001415701 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006234833 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006234834 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006234835 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006234837 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017591733 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039104949 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039104950 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039104951 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039104952 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473949 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JACYVU010000118 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000066181 ⟹ ENSRNOP00000060585 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000090680 ⟹ ENSRNOP00000070846 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000107545 ⟹ ENSRNOP00000090935 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001107766 ⟹ NP_001101236 | ||||||||||||||||||||||||
RefSeq Status: | |||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006234833 ⟹ XP_006234895 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006234834 ⟹ XP_006234896 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006234835 ⟹ XP_006234897 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006234837 ⟹ XP_006234899 | ||||||||||||||||
RefSeq Status: | |||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039104949 ⟹ XP_038960877 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039104950 ⟹ XP_038960878 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039104951 ⟹ XP_038960879 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039104952 ⟹ XP_038960880 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001101236 | (Get FASTA) | NCBI Sequence Viewer |
NP_001402630 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006234895 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006234896 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006234897 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006234899 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038960877 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038960878 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038960879 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038960880 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDL79965 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001101236 ⟸ NM_001107766 |
- Sequence: |
RefSeq Acc Id: | XP_006234899 ⟸ XM_006234837 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6AER0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006234897 ⟸ XM_006234835 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2JYZ1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006234895 ⟸ XM_006234833 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2JYZ1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006234896 ⟸ XM_006234834 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2JYZ1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000070846 ⟸ ENSRNOT00000090680 |
RefSeq Acc Id: | ENSRNOP00000060585 ⟸ ENSRNOT00000066181 |
RefSeq Acc Id: | XP_038960877 ⟸ XM_039104949 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_038960879 ⟸ XM_039104951 |
- Peptide Label: | isoform X5 |
RefSeq Acc Id: | XP_038960878 ⟸ XM_039104950 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_038960880 ⟸ XM_039104952 |
- Peptide Label: | isoform X6 |
RefSeq Acc Id: | ENSRNOP00000090935 ⟸ ENSRNOT00000107545 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-A0A0G2JYZ1-F1-model_v2 | AlphaFold | A0A0G2JYZ1 | 1-1242 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1311661 | AgrOrtholog |
BioCyc Gene | G2FUF-48156 | BioCyc |
Ensembl Genes | ENSRNOG00000011059 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000060585.1 | UniProtKB/TrEMBL |
ENSRNOP00000070846 | ENTREZGENE | |
ENSRNOP00000070846.1 | UniProtKB/TrEMBL | |
ENSRNOP00000090935 | ENTREZGENE | |
ENSRNOP00000090935.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000066181.3 | UniProtKB/TrEMBL |
ENSRNOT00000090680 | ENTREZGENE | |
ENSRNOT00000090680.2 | UniProtKB/TrEMBL | |
ENSRNOT00000107545 | ENTREZGENE | |
ENSRNOT00000107545.1 | UniProtKB/TrEMBL | |
InterPro | Kinase-like_dom | UniProtKB/TrEMBL |
Prot_kinase_cat_dom | UniProtKB/TrEMBL | |
Protein_kinase_ATP_BS | UniProtKB/TrEMBL | |
KEGG Report | rno:311349 | UniProtKB/TrEMBL |
NCBI Gene | 311349 | ENTREZGENE |
Pfam | Pkinase | UniProtKB/TrEMBL |
PhenoGen | Ttbk2 | PhenoGen |
PROSITE | PROTEIN_KINASE_ATP | UniProtKB/TrEMBL |
PROTEIN_KINASE_DOM | UniProtKB/TrEMBL | |
SMART | S_TKc | UniProtKB/TrEMBL |
Superfamily-SCOP | Kinase_like | UniProtKB/TrEMBL |
UniProt | A0A0G2JYZ1 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6AER0 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZN60_RAT | UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-03-07 | Ttbk2 | tau tubulin kinase 2 | Ttbk1_predicted | tau tubulin kinase 1 (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-12 | Ttbk1_predicted | tau tubulin kinase 1 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |