Cat (catalase) - Rat Genome Database

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Gene: Cat (catalase) Rattus norvegicus
Analyze
Symbol: Cat
Name: catalase
RGD ID: 2279
Description: Enables catalase activity. Involved in several processes, including hydrogen peroxide catabolic process; response to ozone; and response to vitamin. Located in extracellular space and peroxisome. Used to study brain ischemia; cholestasis; colitis; and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); end stage renal disease; eye disease (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Orthologous to human CAT (catalase); PARTICIPATES IN disulfiram pharmacodynamics pathway; tryptophan metabolic pathway; amyotrophic lateral sclerosis pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (+)-schisandrin B.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cas1; Cat01; Catl; Cs-1; CS1; RATCAT01; RATCATL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: QTLs:   Tsu1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,297,340 - 110,329,526 (-)NCBIGRCr8
mRatBN7.2389,842,393 - 89,874,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx393,335,845 - 93,368,082 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03101,934,911 - 101,967,152 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0399,765,855 - 99,798,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,379,872 - 93,412,058 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,379,874 - 93,412,058 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03100,021,857 - 100,054,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4388,654,077 - 88,686,212 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1388,550,504 - 88,582,640 (+)NCBI
Celera388,911,241 - 88,943,392 (-)NCBICelera
RH 3.4 Map3718.62RGD
Cytogenetic Map3q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Abnormalities, Drug-Induced  (ISO)
acatalasia  (ISO)
acne  (ISO)
Acute Lung Injury  (ISO)
alcoholic liver cirrhosis  (ISO)
allergic rhinitis  (ISO)
angle-closure glaucoma  (ISO)
aortic disease  (ISO)
asphyxia neonatorum  (ISO)
asthma  (ISO)
autistic disorder  (ISO)
background diabetic retinopathy  (ISO)
bacterial pneumonia  (IDA)
Behcet's disease  (ISO)
Brain Hypoxia-Ischemia  (ISO)
brain ischemia  (IDA,ISO)
breast adenocarcinoma  (ISO)
Breast Neoplasms  (ISO)
bronchopulmonary dysplasia  (IDA)
calcium oxalate nephrolithiasis  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
cataract  (IEP,ISO)
Chemical and Drug Induced Liver Injury  (IEP,ISO)
cholestasis  (IDA,ISO)
Chromosome Breakage  (ISO)
Chronic Hepatitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
chronic venous insufficiency  (ISO)
colitis  (IDA)
colorectal carcinoma  (IEP)
congestive heart failure  (ISO)
COVID-19  (ISO)
cutaneous leishmaniasis  (ISO)
cystitis  (IEP)
depressive disorder  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (IDA,IEP,IMP,ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (IEP)
diffuse large B-cell lymphoma  (ISO)
dilated cardiomyopathy  (ISO)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
Drug-Induced Dyskinesia  (ISO)
Edema  (ISO)
end stage renal disease  (IEP,ISO)
essential hypertension  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (IEP,ISO)
familial mediterranean fever  (ISO)
Femur Head Necrosis  (ISO)
fetal alcohol spectrum disorder  (ISO)
fibromyalgia  (ISO)
focal segmental glomerulosclerosis  (ISO)
gastric adenocarcinoma  (ISO)
gastric ulcer  (IEP,ISO)
genetic disease  (ISO)
Genetic Predisposition to Disease  (ISO)
Graves ophthalmopathy  (ISO)
Graves' disease  (ISO)
Hashimoto Disease  (ISO)
Hearing Loss, Cisplatin-Induced  (IEP)
Hearing Loss, Noise-Induced  (ISO)
hepatitis  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Human Influenza  (ISO)
Huntington's disease  (IEP)
Hyperalgesia  (IEP,IMP)
Hyperemia  (ISO)
Hyperhidrosis  (ISO)
hypertension  (IEP,ISO)
hyperthyroidism  (IEP,ISO)
Hypotension  (ISO)
hypothyroidism  (IEP)
Insulin Resistance  (ISO)
intellectual disability  (ISO)
keratosis  (ISO)
Kidney Calculi  (ISO)
laryngeal squamous cell carcinoma  (ISO)
Left Ventricular Hypertrophy  (IEP)
lichen planus  (ISO)
lung disease  (IDA,IEP,ISO)
lung non-small cell carcinoma  (ISO)
major depressive disorder  (ISO)
Marfan syndrome  (ISO)
melanoma  (ISO)
Mesothelioma  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
myocardial infarction  (IEP,ISO)
Myocardial Reperfusion Injury  (IEP,ISO)
Nasal Polyps  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
neovascular inflammatory vitreoretinopathy  (ISO)
nephrosis  (ISO)
neurodegenerative disease  (IEP)
newborn respiratory distress syndrome  (ISO)
optic neuritis  (ISO)
otitis media  (IEP)
pancreatic cancer  (ISO)
pemphigus  (ISO)
Perennial Allergic Rhinitis  (ISO)
phenylketonuria  (IEP)
phobic disorder  (ISO)
pleurisy  (ISO)
pneumoconiosis  (ISO)
Postmenopausal Osteoporosis  (ISO)
pre-malignant neoplasm  (ISO)
Prehypertension  (IEP)
Premature Birth  (ISO)
Presbycusis  (ISO)
proliferative diabetic retinopathy  (ISO)
Protein Deficiency  (ISO)
pseudoxanthoma elasticum  (ISO)
psoriasis  (ISO)
pterygium  (ISO)
pulmonary edema  (ISO)
pulmonary embolism  (ISO)
pulmonary fibrosis  (ISO)
Raynaud disease  (ISO)
Renoprival Hypertension  (IMP)
Reperfusion Injury  (IDA,IEP,ISO)
Retina Reperfusion Injury  (IEP)
retinal disease  (IEP)
retinitis pigmentosa  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
scabies  (ISO)
sciatic neuropathy  (IEP)
seborrheic dermatitis  (ISO)
senile cataract  (ISO)
sensorineural hearing loss  (IEP)
Sepsis  (IEP)
Skin Neoplasms  (ISO)
status epilepticus  (ISO)
steatotic liver disease  (IEP,ISO)
stomatitis  (IEP)
systemic lupus erythematosus  (ISO)
thyroid gland papillary carcinoma  (ISO)
toxic encephalopathy  (IEP)
Turner syndrome  (ISO)
tympanosclerosis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
Ureteral Calculi  (ISO)
ureteral obstruction  (IEP)
urinary bladder cancer  (ISO)
Viral Bronchiolitis  (ISO)
vitiligo  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-albicanol  (ISO)
(+)-catechin  (EXP,ISO)
(+)-pilocarpine  (EXP,ISO)
(+)-schisandrin B  (EXP)
(+)-sesamin  (EXP,ISO)
(+)-syringaresinol beta-D-glucoside  (ISO)
(+)-taxifolin  (EXP)
(+)-trans-(S)-allethrin  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-quinic acid  (ISO)
(-)-selegiline  (EXP,ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(3,4-dihydroxyphenyl)acetic acid  (ISO)
(E)-cinnamyl alcohol  (ISO)
(E)-thiamethoxam  (EXP,ISO)
(R)-adrenaline  (ISO)
(R)-carnitine  (EXP)
(R)-lipoic acid  (EXP,ISO)
(R)-noradrenaline  (EXP)
(R,R)-tramadol  (EXP)
(R,R,R)-alpha-tocopherol  (EXP,ISO)
(S)-(-)-perillyl alcohol  (EXP,ISO)
(S)-amphetamine  (EXP)
(S)-colchicine  (EXP)
(S)-naringenin  (EXP,ISO)
(S)-nicotine  (EXP,ISO)
(Z)-ligustilide  (ISO)
1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,10-phenanthroline  (ISO)
1,2-dichlorobenzene  (EXP)
1,2-dichloroethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,2-naphthoquinone  (ISO)
1,2-phenylenediamine  (ISO)
1,3-dichloropropan-2-ol  (EXP)
1,4,7-triazonane  (ISO)
1,4-benzoquinone  (ISO)
1,4-dibromobenzene  (EXP)
1,4-dithiothreitol  (ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-benzylpiperazine  (ISO)
1-bromopropane  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
11-deoxycorticosterone  (EXP)
13-HPODE  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
1D-myo-inositol 1,4,5-trisphosphate  (ISO)
1H-imidazole  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrabromodibenzodioxine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,5-trichlorophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-D  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dichlorophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,5-dihydroxybenzoic acid  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (ISO)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-ethoxyethanol  (EXP)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (EXP)
2-methyl-6-(phenylethynyl)pyridine  (EXP,ISO)
2-methylcholine  (ISO)
2-nitropropane  (EXP)
2-palmitoylglycerol  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
26-hydroxycholesterol  (ISO)
3',4',7-trihydroxyisoflavone  (ISO)
3',5'-cyclic GMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-dihydroxybenzaldehyde  (ISO)
3,4-dihydroxybenzoic acid  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-(Methylthio)-1-propene  (EXP)
3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonic acid  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-hydroxypyruvic acid  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-methyladenine  (ISO)
3-methylglutaric acid  (EXP)
3-nitropropanoic acid  (EXP)
3-phenylprop-2-enal  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4'-epidoxorubicin  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(dimethylamino)azobenzene  (ISO)
4-hexylbenzene-1,3-diol  (ISO)
4-hydroxy-TEMPO  (EXP)
4-Hydroxybenzyl isothiocyanate  (EXP)
4-hydroxynon-2-enal  (ISO)
4-methoxycinnamic acid  (EXP)
4-methylumbelliferone  (ISO)
4-nonylphenol  (EXP)
4-vinylcyclohexene dioxide  (ISO)
5-fluorouracil  (EXP,ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-methoxypsoralen  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (EXP)
7,12-dimethyltetraphene  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
7H-xanthine  (ISO)
8-Br-cAMP  (ISO)
9,10-phenanthroquinone  (ISO)
9,11,13-octadecatrienoic acid  (EXP)
9H-xanthine  (ISO)
[6]-Shogaol  (ISO)
abamectin  (EXP)
acephate  (EXP)
acetaldehyde  (ISO)
acetamide  (EXP)
acetamiprid  (EXP,ISO)
acetic acid  (EXP)
acetone  (EXP,ISO)
acetylsalicylic acid  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
acrylic acid  (EXP)
acrylonitrile  (EXP,ISO)
adenine  (EXP)
ADP  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
agomelatine  (EXP)
AICA ribonucleotide  (ISO)
albuterol  (ISO)
aldehydo-D-glucose  (EXP,ISO)
alendronic acid  (EXP,ISO)
alginic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP,ISO)
all-trans-retinyl palmitate  (EXP)
allethrin  (EXP)
allopurinol  (EXP)
alloxan  (EXP,ISO)
Allyl chloride  (EXP)
allyl isothiocyanate  (EXP)
alpha,alpha-trehalose  (EXP)
alpha-Artemisic acid  (ISO)
alpha-D-galactose  (EXP,ISO)
alpha-hexachlorocyclohexane  (EXP)
alpha-hexylcinnamaldehyde  (ISO)
alpha-linolenic acid  (EXP)
alpha-naphthoflavone  (ISO)
alpha-pinene  (EXP)
aluminium atom  (EXP,ISO)
aluminium hydroxide  (EXP)
aluminium oxide  (EXP)
aluminium phosphide  (EXP)
aluminium(0)  (EXP,ISO)
amarogentin  (ISO)
amikacin  (ISO)
aminoacetone  (EXP)
aminoguanidine  (EXP,ISO)
aminophylline  (ISO)
amiodarone  (EXP,ISO)
amitraz  (EXP)
amitriptyline  (ISO)
amitrole  (EXP,ISO)
ammonium acetate  (EXP)
ammonium chloride  (EXP)
Ammothamnine  (EXP)
amosite asbestos  (ISO)
amoxicillin  (EXP)
amphetamine  (ISO)
amphibole asbestos  (ISO)
amphotericin B  (EXP)
andrographolide  (EXP,ISO)
Anemoside B4  (ISO)
anethole  (EXP)
Anetholtrithion  (ISO)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
anthracene-1,8,9-triol  (ISO)
antimycin A  (ISO)
apigenin  (EXP,ISO)
apocynin  (EXP)
aprindine  (ISO)
arachidonic acid  (EXP)
arecoline  (EXP)
aristolochic acid A  (EXP)
arjunolic acid  (EXP,ISO)
Aroclor 1254  (EXP,ISO)
arotinolol  (EXP)
arsane  (EXP,ISO)
arsenic acid  (EXP)
arsenic atom  (EXP,ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
Asiaticoside  (EXP)
aspartame  (EXP,ISO)
astaxanthin  (EXP,ISO)
astemizole  (EXP)
astilbin  (ISO)
atazanavir sulfate  (ISO)
atenolol  (EXP)
atorvastatin calcium  (EXP,ISO)
ATP  (ISO)
atrazine  (EXP,ISO)
aucubin  (ISO)
bacitracin  (EXP)
Bacoside a  (EXP)
Bandrowski's base  (ISO)
barium chloride  (EXP)
barium(0)  (EXP)
beclomethasone  (ISO)
benidipine  (EXP)
benzbromarone  (EXP)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzoic acid  (ISO)
benzopyran  (EXP)
benzoquinones  (ISO)
Benzoyl peroxide  (ISO)
benzyl isothiocyanate  (EXP)
berberine  (EXP,ISO)
Bergenin  (EXP,ISO)
beta-carboline  (ISO)
beta-carotene  (EXP,ISO)
beta-hexachlorocyclohexane  (EXP)
Betanin  (EXP)
betulin  (EXP)
betulinic acid  (EXP)
bezafibrate  (EXP,ISO)
bifenthrin  (EXP,ISO)
biguanides  (EXP)
bilirubin IXalpha  (ISO)
biochanin A  (ISO)
biphenyl-2-ol  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
Bisphenol A glycidylmethacrylate  (ISO)
Bisphenol B  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
Boldine  (ISO)
boric acid  (EXP,ISO)
boron atom  (EXP)
bortezomib  (EXP)
bosentan  (ISO)
Brodifacoum  (EXP)
brucine  (EXP)
Brusatol  (EXP,ISO)
buprenorphine  (EXP,ISO)
buprofezin  (ISO)
bupropion  (ISO)
buspirone  (EXP)
butan-1-ol  (ISO)
butane-2,3-dione  (ISO)
Butralin  (EXP)
butylated hydroxyanisole  (EXP)
Butylbenzyl phthalate  (ISO)
Butylparaben  (EXP)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP,ISO)
calcidiol  (EXP)
calciol  (EXP)
calcium atom  (EXP,ISO)
calcium oxalate  (EXP)
calcium(0)  (EXP,ISO)
calycosin-7-O-beta-D-glucoside  (ISO)
candesartan  (EXP)
cannabidiol  (ISO)
canrenoic acid  (EXP)
capecitabine  (EXP)
capsaicin  (ISO)
captan  (ISO)
carbendazim  (EXP)
carbofuran  (EXP)
carbon atom  (ISO)
carbon disulfide  (EXP)
carbon monoxide  (EXP,ISO)
carbon nanotube  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carboplatin  (EXP)
Cardamonin  (EXP)
carfilzomib  (EXP)
carmustine  (EXP)
carnosic acid  (ISO)
carnosine  (ISO)
carotenoid  (ISO)
carrageenan  (EXP,ISO)
carteolol  (ISO)
carvacrol  (EXP,ISO)
carvedilol  (EXP)
casticin  (ISO)
cefaloridine  (EXP)
cefepime  (ISO)
ceftriaxone  (EXP,ISO)
cefuroxime  (EXP)
celastrol  (EXP,ISO)
celecoxib  (ISO)
ceric oxide  (EXP,ISO)
cerium trichloride  (ISO)
chalcones  (EXP)
chenodeoxycholic acid  (ISO)
chitosan  (EXP)
chloramphenicol  (ISO)
chloric acid  (ISO)
chlorite  (ISO)
chloroform  (EXP)
chlorogenic acid  (EXP,ISO)
chloroquine  (EXP,ISO)
chlorpromazine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
chlorpyrifos-methyl  (EXP)
chlortetracycline  (ISO)
Cholestane-3,5,6-triol  (EXP)
cholesterol  (EXP,ISO)
cholic acid  (EXP)
choline  (ISO)
chondroitin sulfate  (EXP)
chromium atom  (EXP,ISO)
chromium trioxide  (ISO)
chromium(3+) trichloride  (EXP)
chromium(6+)  (EXP,ISO)
chrysene  (ISO)
chrysin  (EXP,ISO)
ciglitazone  (ISO)
cinnamyl alcohol  (ISO)
ciprofibrate  (EXP)
ciprofloxacin  (EXP)
cis-caffeic acid  (EXP,ISO)
cisplatin  (EXP,ISO)
citalopram  (ISO)
citral  (EXP)
citric acid  (ISO)
clemizole  (EXP)
Clinofibrate  (EXP)
clofibrate  (EXP,ISO)
Clofop  (ISO)
clomipramine  (ISO)
clotrimazole  (ISO)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
coenzyme Q10  (EXP,ISO)
colforsin daropate hydrochloride  (EXP)
colistin  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (EXP,ISO)
cordycepin  (EXP,ISO)
corilagin  (EXP,ISO)
corn oil  (ISO)
corticosterone  (ISO)
costunolide  (EXP)
coumarin  (EXP,ISO)
crocidolite asbestos  (EXP,ISO)
crocin-1  (EXP,ISO)
crotonaldehyde  (EXP)
CU-O LINKAGE  (EXP,ISO)
cucurbitacin B  (ISO)
cumene hydroperoxide  (EXP,ISO)
curcumin  (EXP,ISO)
cyanides  (ISO)
cyanocob(III)alamin  (EXP,ISO)
Cyanoginosin  (EXP)
cycloartenol  (ISO)
cycloheximide  (EXP)
Cyclopamine  (EXP,ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP,ISO)
cyhalothrin  (EXP,ISO)
cylindrospermopsin  (EXP,ISO)
cypermethrin  (EXP,ISO)
cytochalasin B  (ISO)
D-glucose  (EXP,ISO)
D-penicillamine  (ISO)
daidzein  (EXP,ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
dapsone  (EXP)
daunorubicin  (ISO)
DDD  (EXP)
DDE  (EXP,ISO)
DDT  (EXP)
decabromodiphenyl ether  (ISO)
Decursin  (ISO)
dehydroascorbic acid  (ISO)
dehydroepiandrosterone  (EXP)
delphinidin  (ISO)
delta-hexachlorocyclohexane  (EXP)
Dendrobine  (ISO)
deoxycholic acid  (ISO)
Deoxycorticosterone acetate  (EXP)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (EXP,ISO)
desogestrel  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diallyl disulfide  (EXP)
Diallyl sulfide  (EXP)
diallyl trisulfide  (EXP)
Diallyltetrasulfane  (EXP)
diarsenic trioxide  (EXP,ISO)
diazepam  (EXP,ISO)
diazinon  (EXP)
diazoxon  (EXP)
dibenziodolium  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (ISO)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
dichlorvos  (EXP,ISO)
dichromium trioxide  (ISO)
diclofenac  (EXP,ISO)
diclofop-methyl  (EXP)
dicoumarol  (EXP,ISO)
dieckol  (ISO)
diethyl maleate  (EXP)
diethyl phthalate  (ISO)
diethyldithiocarbamic acid  (ISO)
difenoconazole  (EXP,ISO)
dihydroactinidiolide  (ISO)
dihydroartemisinin  (ISO)
dihydrocapsaicin  (ISO)
dihydrogen  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diltiazem  (EXP)
dimethoate  (EXP,ISO)
dimethyl fumarate  (EXP)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (EXP)
dimethylarsinous acid  (EXP,ISO)
Diosbulbin B  (ISO)
diosmin  (EXP)
dioxygen  (EXP,ISO)
dipentyl phthalate  (EXP)
diprotium  (ISO)
diprotium oxide  (EXP,ISO)
diquat  (EXP,ISO)
disodium selenite  (EXP)
disulfiram  (ISO)
dithianon  (ISO)
diuron  (EXP)
dizocilpine maleate  (EXP)
Dodecyl gallate  (ISO)
donepezil hydrochloride  (ISO)
dopamine  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ebselen  (EXP)
edaravone  (ISO)
efavirenz  (EXP)
elemental boron  (EXP)
elemental carbon  (ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (EXP)
emamectin benzoate  (ISO)
embelin  (EXP)
emodin  (EXP,ISO)
empagliflozin  (EXP)
enalapril  (EXP)
endosulfan  (EXP,ISO)
enilconazole  (ISO)
enniatin  (ISO)
enrofloxacin  (EXP)
enzyme inhibitor  (EXP)
eplerenone  (EXP)
erdosteine  (EXP)
Eremanthin  (EXP)
ergothioneine  (EXP)
eriodictyol  (EXP)
erythromycin A  (ISO)
erythromycin estolate  (EXP)
etacrynic acid  (ISO)
etanidazole  (ISO)
ethambutol  (EXP)
ethanol  (EXP,ISO)
Ethyl 4-methoxycinnamate  (EXP)
ethylbenzene  (EXP)
ethylene glycol  (EXP)
ethylenediaminetetraacetic acid  (ISO)
etoposide  (EXP,ISO)
eugenol  (EXP,ISO)
eumelanin  (ISO)
excitatory amino acid agonist  (EXP)
famotidine  (EXP)
farnesol  (EXP,ISO)
fenitrothion  (EXP)
fenofibrate  (EXP)
fenoterol  (ISO)
fenpropathrin  (EXP)
fenpyroximate  (EXP,ISO)
fenvalerate  (EXP)
ferric oxide  (ISO)
ferrocene  (EXP)
ferruginol  (EXP)
ferulic acid  (EXP,ISO)
finasteride  (EXP)
fipronil  (EXP,ISO)
fisetin  (EXP)
flavonoids  (EXP,ISO)
flubendiamide  (EXP)
fludioxonil  (ISO)
fluorene  (ISO)
fluoxetine  (EXP)
fluphenazine  (EXP)
flutamide  (EXP)
fluvastatin  (EXP,ISO)
folic acid  (EXP,ISO)
folpet  (ISO)
formaldehyde  (EXP,ISO)
fraxetin  (ISO)
fructose  (EXP,ISO)
fucoxanthin  (ISO)
fumonisin B1  (EXP,ISO)
furan  (EXP,ISO)
furans  (ISO)
gadolinium atom  (ISO)
gadolinium trichloride  (EXP)
galactose  (EXP,ISO)
galangin  (EXP)
Galbanic acid  (ISO)
gallein  (EXP)
gallic acid  (EXP,ISO)
gamma-aminobutyric acid  (EXP,ISO)
gamma-hexachlorocyclohexane  (EXP,ISO)
gamma-Oryzanol (TN)  (ISO)
gamma-tocopherol  (ISO)
Ganoderic acid T  (ISO)
gemfibrozil  (EXP,ISO)
Geniposide  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
geranial  (EXP)
geraniol  (EXP,ISO)
gingerol  (EXP,ISO)
Ginkgolide C  (EXP)
ginsenoside Rd  (EXP)
ginsenoside Re  (ISO)
ginsenoside Rg1  (ISO)
glafenine  (EXP)
gliclazide  (EXP)
glucagon  (ISO)
glucose  (EXP,ISO)
glutathione  (EXP,ISO)
Glutathione ethyl ester  (EXP)
glyburide  (EXP,ISO)
glycerol  (EXP)
glycine betaine  (EXP,ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycolaldehyde  (EXP)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
glyoxal  (EXP)
glyphosate  (EXP,ISO)
gold atom  (ISO)
gold(0)  (ISO)
gossypin  (EXP)
gossypol  (ISO)
haloperidol  (EXP,ISO)
harman  (ISO)
hemin  (EXP,ISO)
heparin  (ISO)
herbicide  (ISO)
hesperetin  (EXP,ISO)
hesperidin  (EXP,ISO)
hexachlorobenzene  (EXP,ISO)
hexadecanoic acid  (EXP,ISO)
hexaflumuron  (EXP)
histamine  (EXP,ISO)
homocysteine  (ISO)
Honokiol  (EXP)
hyaluronic acid  (ISO)
hydrazine  (EXP)
hydrochlorothiazide  (EXP)
hydrogen chloride  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP,ISO)
hydroquinone O-beta-D-glucopyranoside  (EXP)
hydroxyl  (ISO)
hydroxylamine  (ISO)
hydroxysafflor yellow A  (ISO)
hydroxytyrosol  (EXP,ISO)
hymexazol  (EXP)
hypochlorous acid  (ISO)
iberin  (EXP)
ifosfamide  (EXP)
imetit  (EXP)
imidacloprid  (EXP)
Imipenem-cilastatin  (EXP)
imipramine  (EXP,ISO)
imiprothrin  (EXP)
immunological adjuvant  (EXP)
indirubin-3'-monoxime  (ISO)
indole-3-acetic acid  (ISO)
indole-3-methanol  (EXP,ISO)
indometacin  (EXP,ISO)
inositol  (EXP)
inulin  (ISO)
iron atom  (EXP,ISO)
iron dextran  (EXP,ISO)
iron trichloride  (ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (ISO)
iron(III) nitrilotriacetate  (EXP)
isoeugenol  (ISO)
isoflurane  (ISO)
isoliquiritigenin  (EXP,ISO)
isoniazide  (EXP,ISO)
isoprenaline  (EXP,ISO)
isorhamnetin  (EXP)
isotretinoin  (EXP,ISO)
ivermectin  (EXP,ISO)
juglone  (ISO)
kaempferol  (EXP,ISO)
kaempferol 3-O-beta-D-glucoside  (ISO)
kainic acid  (EXP,ISO)
ketamine  (EXP)
ketoconazole  (EXP)
ketorolac tromethamine  (EXP)
Kirenol  (ISO)
kojic acid  (EXP)
L-1,4-dithiothreitol  (ISO)
L-arginine  (EXP,ISO)
L-ascorbic acid  (EXP,ISO)
L-cysteine  (EXP)
L-dehydroascorbic acid  (ISO)
L-gamma-glutamyl-L-cysteine  (EXP)
L-methionine  (ISO)
L-mimosine  (ISO)
lactose  (EXP)
lamivudine  (EXP)
lansoprazole  (EXP)
lead diacetate  (EXP,ISO)
lead nitrate  (EXP,ISO)
lead(0)  (EXP,ISO)
lead(II) chloride  (EXP,ISO)
leflunomide  (ISO)
lenvatinib  (EXP)
Leonurine  (EXP)
letrozole  (ISO)
levetiracetam  (EXP,ISO)
levonorgestrel  (ISO)
limonene  (EXP)
limonin  (ISO)
linalool  (EXP)
linoleic acid  (EXP,ISO)
linsidomine  (ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (EXP,ISO)
lithium carbonate  (EXP,ISO)
lithium hydride  (EXP,ISO)
loperamide  (EXP)
lopinavir  (ISO)
losartan  (EXP)
lovastatin  (EXP)
lupeol  (EXP,ISO)
lutein  (ISO)
luteolin  (ISO)
luteolin 7-O-beta-D-glucoside  (ISO)
luzindole  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP,ISO)
m-xylene  (EXP)
maculosin  (ISO)
magnesium oxide  (EXP)
magnesium sulfate  (EXP)
Magnolol  (EXP)
malaoxon  (ISO)
malathion  (EXP,ISO)
malonaldehyde  (EXP)
mancozeb  (EXP,ISO)
maneb  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
mangiferin  (EXP,ISO)
medroxyprogesterone  (ISO)
medroxyprogesterone acetate  (ISO)
melatonin  (EXP,ISO)
meloxicam  (ISO)
melphalan  (ISO)
menadione  (EXP,ISO)
mephedrone  (EXP,ISO)
mercaptoethanol  (ISO)
mercury atom  (EXP)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP)
metam  (ISO)
Metanephrine  (ISO)
metformin  (EXP,ISO)
methamidophos  (EXP)
methamphetamine  (EXP,ISO)
methanol  (ISO)
methapyrilene  (EXP)
methimazole  (EXP,ISO)
methotrexate  (EXP,ISO)
methoxychlor  (EXP,ISO)
Methylacrylonitrile  (EXP)
methylarsonic acid  (EXP)
methylglyoxal  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
methylparaben  (ISO)
methylphenidate  (EXP)
Mezerein  (ISO)
miconazole  (EXP)
microcystin-LR  (EXP,ISO)
mifepristone  (EXP,ISO)
miquelianin  (EXP)
mirabegron  (EXP)
mirtazapine  (EXP)
misoprostol  (EXP)
mitogen  (EXP)
mitoxantrone  (EXP)
molybdenum trioxide  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monocrotaline  (EXP)
monocrotophos  (EXP)
monoethyl phthalate  (ISO)
monooxygen  (ISO)
monosodium L-glutamate  (EXP,ISO)
montelukast  (EXP)
morin  (EXP)
morphine  (ISO)
Muraglitazar  (EXP)
myo-inositol hexakisphosphate  (EXP)
myricetin  (EXP,ISO)
myricitrin  (ISO)
myrsinoic acid B  (EXP)
myrtenol  (EXP)
N'-(2,4-dimethylphenyl)-N-methylformamidine  (EXP)
N,N'-diphenyl-1,4-phenylenediamine  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N,N-Diethylbenzamide  (EXP)
N,N-dimethylacetamide  (ISO)
N,N-dimethylformamide  (ISO)
N,N-dimethylglycine  (ISO)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylserotonin  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
NADP zwitterion  (EXP)
NADP(+)  (EXP)
nafenopin  (EXP)
naloxone  (EXP)
naphthalene-1,2-diol  (ISO)
naringin  (EXP,ISO)
nebivolol  (EXP)
nefazodone  (ISO)
Neferine  (EXP)
neoastilbin  (ISO)
neocuproine  (EXP)
neohesperidin dihydrochalcone  (ISO)
nerolidol  (EXP)
nevadensin  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (EXP,ISO)
nicorandil  (EXP)
nicotinamide  (EXP,ISO)
nicotine  (EXP,ISO)
nicotinic acid  (EXP)
nimesulide  (EXP,ISO)
nimodipine  (EXP)
nitric oxide  (EXP)
nitrofen  (EXP)
nitrofurantoin  (EXP,ISO)
nitrogen dioxide  (EXP,ISO)
nitroglycerin  (EXP)
nitroprusside  (EXP,ISO)
nitroxoline  (ISO)
Nonylphenol  (EXP)
norwogonin  (EXP)
notoginsenoside R1  (EXP)
NS-398  (ISO)
O-acetyl-L-carnitine  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP,ISO)
octadecanoic acid  (EXP)
octyl gallate  (ISO)
okadaic acid  (ISO)
olanzapine  (EXP)
oleanolic acid  (EXP,ISO)
oleic acid  (EXP,ISO)
oleuropein  (EXP,ISO)
oligopeptide  (ISO)
Olmesartan medoxomil  (EXP)
omeprazole  (EXP,ISO)
Ondansetron  (ISO)
oridonin  (EXP)
orlistat  (EXP,ISO)
osimertinib  (ISO)
ouabain  (EXP)
oxalic acid  (ISO)
oxaliplatin  (EXP,ISO)
oxidopamine  (EXP)
Oxyfluorfen  (ISO)
oxytetracycline  (ISO)
ozone  (EXP,ISO)
p-toluidine  (EXP)
Pachymic acid  (EXP)
paclitaxel  (EXP,ISO)
Paeonol  (ISO)
Palbinone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion-methyl  (EXP)
paroxetine  (ISO)
parthenolide  (EXP)
patchouli alcohol  (EXP)
patulin  (ISO)
pendimethalin  (EXP)
pentachlorophenol  (EXP)
pentetrazol  (EXP,ISO)
Pentoxifylline  (EXP,ISO)
peptidoglycan  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perillyl alcohol  (EXP,ISO)
perindopril  (EXP)
permethrin  (EXP,ISO)
peroxides  (ISO)
peroxynitrous acid  (ISO)
PHA-665752  (ISO)
phenanthrene  (ISO)
phenethyl caffeate  (EXP,ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (EXP,ISO)
phenylephrine  (EXP)
phenylpropanolamine  (EXP)
phenytoin  (ISO)
PhIP  (EXP,ISO)
phloretin  (EXP)
phlorizin  (ISO)
phorate  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphamidon  (ISO)
phytol  (ISO)
piclamilast  (EXP)
pinitol  (EXP,ISO)
pinostrobin  (EXP)
pioglitazone  (EXP,ISO)
piperazine  (ISO)
piperine  (EXP,ISO)
pipoxolan  (ISO)
Piracetam  (ISO)
pirfenidone  (EXP,ISO)
pirinixic acid  (EXP,ISO)
platycodin D  (ISO)
plumbagin  (EXP)
pluronic P-123  (EXP)
Poloxamer  (EXP)
poly(I:C)  (EXP)
ponatinib  (ISO)
porphyrins  (ISO)
potassium bromate  (EXP,ISO)
potassium chloride  (EXP)
potassium chromate  (ISO)
potassium dichromate  (EXP,ISO)
pralidoxime  (ISO)
pravastatin  (ISO)
prednisolone  (EXP)
proanthocyanidin  (EXP,ISO)
probenecid  (ISO)
procyanidin B1  (ISO)
procyanidin B2  (EXP,ISO)
procyanidin B3  (ISO)
prodigiosin  (EXP)
profenofos  (EXP)
propacetamol  (ISO)
propetamphos  (EXP,ISO)
propiconazole  (EXP,ISO)
propionic acid  (EXP)
Propiverine  (EXP)
propofol  (EXP,ISO)
propoxur  (EXP)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (EXP)
psoralen  (EXP)
pterostilbene  (ISO)
puerarin  (EXP)
Punicalagin  (EXP)
pyrazine-2-carboxylic acid  (EXP)
pyrazinecarboxamide  (EXP)
pyrethrins  (EXP)
Pyridostigmine bromide  (EXP,ISO)
pyrimethamine  (ISO)
pyrogallol  (EXP,ISO)
pyrroloquinoline quinone  (EXP)
pyrvinium  (EXP)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
quercetin 3-O-beta-D-glucofuranoside  (EXP)
quercetin 3-O-beta-D-glucopyranoside  (EXP)
quercetin 4'-O-beta-D-glucopyranoside  (ISO)
quetiapine fumarate  (EXP)
quinalphos  (EXP,ISO)
quinidine  (ISO)
quinolinic acid  (EXP)
quinolone  (ISO)
quinoxyfen  (ISO)
quizalofop-ethyl  (EXP)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ramipril  (EXP)
ranitidine  (EXP)
reactive oxygen species  (EXP,ISO)
rebaudioside A  (ISO)
Repaglinide  (EXP)
reserpine  (EXP)
resveratrol  (EXP,ISO)
riboflavin  (EXP)
rifampicin  (EXP)
rivastigmine  (EXP)
rofecoxib  (EXP)
roflumilast  (EXP)
ropinirole  (EXP)
rosmarinic acid  (ISO)
rosuvastatin calcium  (EXP)
rotenone  (EXP,ISO)
royal jelly  (EXP,ISO)
ruthenium atom  (EXP)
rutin  (EXP,ISO)
ruxolitinib  (ISO)
ryanodine  (EXP)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
S-allylcysteine  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
Salidroside  (EXP,ISO)
Salvianolic acid A  (EXP,ISO)
sanguinarine  (ISO)
SB 203580  (ISO)
scopolamine  (ISO)
selenium atom  (EXP,ISO)
selenocystine  (ISO)
selenomethionine  (ISO)
serotonin  (ISO)
sertraline  (EXP)
Sesamol  (EXP)
sevoflurane  (EXP)
sildenafil citrate  (EXP,ISO)
silibinin  (EXP)
silicic acid  (ISO)
silicon atom  (EXP,ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
silver(1+) nitrate  (ISO)
simvastatin  (EXP,ISO)
sinapic acid  (EXP)
sirolimus  (ISO)
sodium acetate trihydrate  (EXP,ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium benzoate  (EXP)
sodium chlorate  (EXP)
sodium dichromate  (EXP,ISO)
sodium fluoride  (EXP,ISO)
sodium hydrogencarbonate  (ISO)
sodium nitrate  (EXP)
sodium nitrite  (ISO)
solanesol  (ISO)
soybean oil  (EXP)
squalene  (EXP)
starch  (ISO)
sterigmatocystin  (EXP)
steviol  (ISO)
stevioside  (ISO)
streptozocin  (EXP,ISO)
styrene  (ISO)
succimer  (EXP)
sucrose  (EXP,ISO)
sulfasalazine  (EXP,ISO)
sulfonyldimethane  (EXP)
sulforaphane  (EXP,ISO)
sulfoxaflor  (EXP)
sulfur dioxide  (EXP)
sulpiride  (ISO)
sunitinib  (EXP,ISO)
Sunset Yellow FCF  (ISO)
superoxide  (ISO)
surfactin  (ISO)
surfactin C  (ISO)
syringic acid  (EXP,ISO)
T-2 toxin  (EXP,ISO)
tacrine  (ISO)
tacrolimus hydrate  (EXP,ISO)
tadalafil  (EXP)
tamoxifen  (EXP,ISO)
tangeretin  (EXP)
tannic acid  (EXP)
taraxerone  (ISO)
tartrazine  (EXP,ISO)
taurine  (EXP,ISO)
tebuconazole  (EXP)
tebufenpyrad  (ISO)
tectorigenin  (ISO)
telmisartan  (EXP)
tembotrione  (EXP)
tenofovir disoproxil fumarate  (EXP)
tert-butyl hydroperoxide  (EXP,ISO)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
testosterone cypionate  (ISO)
Testosterone propionate  (EXP)
tetrachloro-1,4-benzoquinone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP,ISO)
tetracyclines  (ISO)
tetrahydrocurcumin  (EXP,ISO)
tetramethylpyrazine  (ISO)
thalidomide  (ISO)
thallium  (EXP)
thapsigargin  (EXP)
theophylline  (EXP)
thiacloprid  (EXP)
thiamethoxam  (EXP,ISO)
thiazoles  (ISO)
thioacetamide  (EXP)
thymol  (EXP,ISO)
thymol sulfate(1-)  (EXP,ISO)
thymoquinone  (EXP,ISO)
thyroxine  (EXP)
tiadenol  (EXP)
tianeptine  (EXP)
tirapazamine  (EXP)
Tiron  (ISO)
titanium atom  (ISO)
titanium dioxide  (EXP,ISO)
toluene  (ISO)
Tomentosin  (ISO)
topotecan  (ISO)
toxaphene  (ISO)
tramadol  (EXP)
trandolapril  (EXP)
trans-anethole  (EXP)
trans-caffeic acid  (EXP,ISO)
trans-cinnamic acid  (EXP,ISO)
trans-isoeugenol  (ISO)
trans-piceid  (EXP,ISO)
trans-rhaponticin  (EXP)
trazodone  (ISO)
triadimefon  (EXP)
tributyl phosphate  (EXP)
tributylstannane  (EXP,ISO)
trichlorfon  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (EXP,ISO)
triflumuron  (ISO)
trilobatin  (ISO)
triolein  (EXP)
triphenyl phosphate  (EXP,ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (EXP,ISO)
tris(picolinato)chromium  (EXP)
troglitazone  (EXP,ISO)
tuberostemonine  (ISO)
Tungsten carbide  (ISO)
tyramine  (EXP)
ubiquinones  (EXP)
umbelliferone  (ISO)
urethane  (ISO)
ursolic acid  (ISO)
usnic acid  (EXP)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vanadium atom  (EXP)
vanadium(0)  (EXP)
vanadyl sulfate  (ISO)
vancomycin  (EXP,ISO)
vanillin  (EXP,ISO)
venlafaxine hydrochloride  (EXP)
vincaleukoblastine  (ISO)
vincristine  (EXP,ISO)
Vinpocetine  (EXP)
vitamin E  (EXP,ISO)
vitamin K  (EXP)
warfarin  (EXP)
water  (EXP,ISO)
wedelolactone  (ISO)
withaferin A  (EXP,ISO)
wogonin  (EXP,ISO)
WR-1065  (ISO)
yohimbine  (EXP)
zafirlukast  (EXP)
zearalenone  (EXP,ISO)
zidovudine  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP,ISO)
zinc molecular entity  (EXP)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (EXP,ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zingerone  (EXP)
ziprasidone  (EXP)
ziram  (ISO)
zolpidem  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
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36. Gastroprotective and antioxidant effects of montelukast on indomethacin-induced gastric ulcer in rats. Dengiz GO, etal., J Pharmacol Sci. 2007 Sep;105(1):94-102.
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38. Activity of superoxide dismutase and catalase and the level of lipid peroxidation products reactive with TBA in patients with psoriasis. Drewa G, etal., Med Sci Monit. 2002 Aug;8(8):BR338-43.
39. Adenosine deaminase, 5' nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in cancerous and noncancerous human laryngeal tissues. Durak I, etal., Free Radic Biol Med. 1993 Dec;15(6):681-4. doi: 10.1016/0891-5849(93)90174-s.
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46. Prophylaxis and therapeutic effects of raspberry (Rubus idaeus) on renal stone formation in Balb/c mice. Ghalayini IF, etal., Int Braz J Urol. 2011 Mar-Apr;37(2):259-66; discussion 267.
47. Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation. Ghosh S, etal., J Immunol. 2006 May 1;176(9):5587-97.
48. Genetic polymorphisms of antioxidant enzymes as risk factors for oxidative stress-associated complications in preterm infants. Giusti B, etal., Free Radic Res. 2012 Sep;46(9):1130-9. doi: 10.3109/10715762.2012.692787. Epub 2012 Jun 13.
49. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
50. Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes. Graham S, etal., Am J Physiol Cell Physiol. 2011 Aug;301(2):C304-15. doi: 10.1152/ajpcell.00014.2011. Epub 2011 Apr 27.
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54. Antioxidant enzymes and melatonin levels in patients with bronchial asthma and chronic obstructive pulmonary disease during stable and exacerbation periods. Gumral N, etal., Cell Biochem Funct. 2009 Jul;27(5):276-83.
55. Curcumin Prevents Experimental Diabetic Retinopathy in Rats Through Its Hypoglycemic, Antioxidant, and Anti-Inflammatory Mechanisms. Gupta SK, etal., J Ocul Pharmacol Ther. 2011 Feb 12.
56. The connection of monocytes and reactive oxygen species in pain. Hackel D, etal., PLoS One. 2013 May 2;8(5):e63564. doi: 10.1371/journal.pone.0063564. Print 2013.
57. Reduction in oxidative stress and modulation of heart failure subsequent to myocardial infarction in rats. Hill MF, etal., Exp Clin Cardiol. 2005 Fall;10(3):146-53.
58. Viral-mediated Inhibition of Antioxidant Enzymes Contributes to the Pathogenesis of Severe RSV Bronchiolitis. Hosakote YM, etal., Am J Respir Crit Care Med. 2011 Mar 4.
59. Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway. Huang T, etal., Oxid Med Cell Longev. 2019 Jul 15;2019:5813985. doi: 10.1155/2019/5813985. eCollection 2019.
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62. Time response of carboplatin-induced hearing loss in rat. Husain K, etal., Hear Res. 2004 May;191(1-2):110-8.
63. Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction. Hwang I, etal., Diabetes. 2012 Mar;61(3):728-38. doi: 10.2337/db11-0584. Epub 2012 Feb 7.
64. Therapeutic effects of acupuncture with MOK, a polyherbal medicine, on PTU-induced hypothyroidism in rats. Hwang JH, etal., Exp Ther Med. 2018 Jul;16(1):310-320. doi: 10.3892/etm.2018.6190. Epub 2018 May 18.
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67. Erythrocyte oxidant/antioxidant status in essential hyperhidrosis. Karaca S, etal., Mol Cell Biochem. 2006 Oct;290(1-2):131-5. Epub 2006 May 23.
68. Comparison of free radicals and antioxidant enzymes in chronic otitis media with and without tympanosclerosis. Karlidag T, etal., Laryngoscope. 2004 Jan;114(1):85-9.
69. Black Tea Prevents High Fat Diet-induced Non-alcoholic Steatohepatitis. Karmakar S, etal., Phytother Res. 2011 Mar 31. doi: 10.1002/ptr.3466.
70. Oxidative stress profile in graves' ophthalmopathy in Indian patients. Kaur A, etal., Orbit. 2010 Apr;29(2):97-101. doi: 10.3109/01676830903403174.
71. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
72. Antioxidant enzyme gene expression in congestive heart failure following myocardial infarction. Khaper N, etal., Mol Cell Biochem. 2003 Sep;251(1-2):9-15.
73. Red blood cells induce hypoxic lung inflammation. Kiefmann R, etal., Blood. 2008 May 15;111(10):5205-14. Epub 2008 Feb 12.
74. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
75. Hyperbaric oxygenation pretreatment induces catalase and reduces infarct size in ischemic rat myocardium. Kim CH, etal., Pflugers Arch. 2001 Jul;442(4):519-25.
76. Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. Kim HJ and Vaziri ND, Am J Physiol Renal Physiol. 2010 Mar;298(3):F662-71. Epub 2009 Dec 9.
77. Genetic association study of polymorphisms in the catalase gene with the risk of osteonecrosis of the femoral head in the Korean population. Kim TH, etal., Osteoarthritis Cartilage. 2008 Sep;16(9):1060-6. doi: 10.1016/j.joca.2008.02.004. Epub 2008 Mar 18.
78. Alterations of serum selenium, zinc, copper, and iron concentrations and some related antioxidant enzyme activities in patients with cutaneous leishmaniasis. Kocyigit A, etal., Biol Trace Elem Res. 1998 Dec;65(3):271-81.
79. Association between variations in CAT and noise-induced hearing loss in two independent noise-exposed populations. Konings A, etal., Hum Mol Genet. 2007 Aug 1;16(15):1872-83. Epub 2007 Jun 13.
80. Response of anti-oxidant enzymes mRNA in the neonatal rat liver exposed to 1,2,3,4-tetrachlorodibenzo-p-dioxin via lactation. Kono Y, etal., Pediatr Int. 2002 Oct;44(5):481-7.
81. Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations. Kumar P and Kumar A, Eur J Pharmacol. 2009 Aug 1;615(1-3):91-101. Epub 2009 May 13.
82. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
83. A comparative study of the oxidative profile in Graves' disease, Hashimoto's thyroiditis, and papillary thyroid cancer. Lassoued S, etal., Biol Trace Elem Res. 2010 Dec;138(1-3):107-15. doi: 10.1007/s12011-010-8625-1. Epub 2010 Mar 5.
84. Protective effects and mechanism of tetramethylpyrazine against lens opacification induced by sodium selenite in rats. Li N, etal., Exp Eye Res. 2011 Jul;93(1):98-102. doi: 10.1016/j.exer.2011.05.001. Epub 2011 May 27.
85. Antioxidant status and immune activity of glycyrrhizin in allergic rhinitis mice. Li XL, etal., Int J Mol Sci. 2011 Jan 26;12(2):905-16. doi: 10.3390/ijms12020905.
86. Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. Liu KM, etal., Am J Physiol Renal Physiol. 2015 Aug 15;309(4):F318-31. doi: 10.1152/ajprenal.00607.2014. Epub 2015 Jun 24.
87. Promoter variant in the catalase gene is associated with vitiligo in Chinese people. Liu L, etal., J Invest Dermatol. 2010 Nov;130(11):2647-53. doi: 10.1038/jid.2010.192. Epub 2010 Jul 8.
88. Pain-relieving effects of pulsed magnetic fields in a rat model of carrageenan-induced hindpaw inflammation. Mert T, etal., Int J Radiat Biol. 2014 Jan;90(1):95-103. doi: 10.3109/09553002.2013.835501. Epub 2013 Sep 13.
89. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
90. Ovariectomy increases Na+, K+-ATPase, acetylcholinesterase and catalase in rat hippocampus. Monteiro SC, etal., Mol Cell Endocrinol. 2005 May 31;236(1-2):9-16.
91. Role of catalase and superoxide dismutase activities on oxidative stress in the brain of a phenylketonuria animal model and the effect of lipoic acid. Moraes TB, etal., Cell Mol Neurobiol. 2013 Mar;33(2):253-60. doi: 10.1007/s10571-012-9892-5. Epub 2012 Dec 12.
92. Improvement of renal oxidative stress markers after ozone administration in diabetic nephropathy in rats. Morsy MD, etal., Diabetol Metab Syndr. 2010 May 13;2(1):29. doi: 10.1186/1758-5996-2-29.
93. Hyperoxia-induced lung injury is dose dependent in Wistar rats. Nagato A, etal., Exp Lung Res. 2009 Oct;35(8):713-28.
94. A variant in myeloperoxidase promoter hastens the emergence of hepatocellular carcinoma in patients with HCV-related cirrhosis. Nahon P, etal., J Hepatol. 2012 Feb;56(2):426-32. doi: 10.1016/j.jhep.2011.08.010. Epub 2011 Sep 8.
95. Isolation and characterization of the rat catalase-encoding gene. Nakashima H, etal., Gene 1989 Jul 15;79(2):279-88.
96. Isolation and characterization of the rat catalase-encoding gene. Nakashima H, etal., Gene 1990 May 14;89(2):295.
97. Daily rhythms of catalase and glutathione peroxidase expression and activity are endogenously driven in the hippocampus and are modified by a vitamin A-free diet. Navigatore-Fonzo LS, etal., Nutr Neurosci. 2014 Jan;17(1):21-30. doi: 10.1179/1476830513Y.0000000062. Epub 2013 Nov 26.
98. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
99. Bilirubin is highly effective in preventing in vivo delta-aminolevulinic acid-induced oxidative cell damage. Noriega GO, etal., Biochim Biophys Acta 2003 Jul 14;1638(2):173-8.
100. Comparative effect of topical application of lindane and permethrin on oxidative stress parameters in adult scabies patients. Oberoi S, etal., Clin Biochem. 2007 Nov;40(16-17):1321-4. Epub 2007 Aug 10.
101. The role of catalase in pulmonary fibrosis. Odajima N, etal., Respir Res. 2010 Dec 29;11:183.
102. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
103. Oxidative stress in patients with scalp seborrheic dermatitis. Ozturk P, etal., Acta Dermatovenerol Croat. 2013 Aug;21(2):80-5.
104. Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia. Pan L, etal., World J Pediatr. 2009 Aug;5(3):216-21. Epub 2009 Aug 20.
105. The activity of adenosine deaminase and oxidative stress biomarkers in scraping samples of acne lesions. Perihan O, etal., J Cosmet Dermatol. 2012 Dec;11(4):323-8. doi: 10.1111/jocd.12011.
106. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
107. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
108. Oxidative stress and endothelial dysfunction in pulmonary arteries of aged rats. Podlutsky A, etal., Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H346-51. Epub 2009 Dec 4.
109. Tobacco smoking, fruit and vegetable intake modify association between -21A>T polymorphism of catalase gene and risk of bronchial asthma. Polonikov AV, etal., J Asthma. 2009 Apr;46(3):217-24.
110. Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. Qamar W and Sultana S, Chem Biol Interact. 2008 Nov 25;176(2-3):79-87. Epub 2008 Aug 28.
111. Polyphenols from Juglans regia L. (Walnut) kernel modulate cigarette smoke extract induced acute inflammation, oxidative stress and lung injury in Wistar rats. Qamar W and Sultana S, Hum Exp Toxicol. 2010 Jun 9.
112. Long-term suppression of neurodegeneration in chronic experimental optic neuritis: antioxidant gene therapy. Qi X, etal., Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5360-70.
113. Novel 1,4-benzothazines obliterate COX-2 mediated JAK-2/STAT-3 signals with potential regulation of oxidative and metabolic stress during colorectal cancer. Rai A, etal., Pharmacol Res. 2018 Jun;132:188-203. doi: 10.1016/j.phrs.2017.12.010. Epub 2017 Dec 8.
114. Free Radical Scavenging Activity of Calotropis gigantea on Streptozotocin-Induced Diabetic Rats. Rathod NR, etal., Indian J Pharm Sci. 2009 Nov;71(6):615-21.
115. Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase. Reiners JJ Jr, etal., Carcinogenesis. 1991 Dec;12(12):2337-43.
116. Evaluating D-methionine dose to attenuate oxidative stress-mediated hearing loss following overexposure to noise. Rewerska A, etal., Eur Arch Otorhinolaryngol. 2013 Mar;270(4):1513-20. doi: 10.1007/s00405-012-2265-3. Epub 2012 Nov 18.
117. GOA pipeline RGD automated data pipeline
118. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
119. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
120. Dose dependent protection by lipoic acid against cisplatin-induced ototoxicity in rats: antioxidant defense system. Rybak LP, etal., Toxicol Sci. 1999 Feb;47(2):195-202.
121. Influence of desloratadine on selected oxidative stress markers in patients between 3 and 10 years of age with allergic perennial rhinitis. Sadowska-Woda I, etal., Eur J Pharmacol. 2010 Aug 25;640(1-3):197-201. Epub 2010 May 21.
122. Marked changes in erythrocyte antioxidants and lipid peroxidation levels of rats exposed to acute, repeated and chronic restraint stress. Sahin E, etal., Pharmazie. 2004 Dec;59(12):961-4.
123. Catalase takes part in rat liver mitochondria oxidative stress defense. Salvi M, etal., J Biol Chem. 2007 Aug 17;282(33):24407-15. Epub 2007 Jun 18.
124. A fungal Cu/Zn-containing superoxide dismutase enhances the therapeutic efficacy of a plant polyphenol extract in experimental influenza virus infection. Serkedjieva J, etal., Z Naturforsch C. 2010 May-Jun;65(5-6):419-28.
125. Attenuation of endogenous oxidative stress-induced cell death by cytochrome P450 inhibitors in primary cultures of rat hepatocytes. Shiba D and Shimamoto N, Free Radic Biol Med. 1999 Nov;27(9-10):1019-26.
126. Expression of catalase and glutathione peroxidase in renal insufficiency. Sindhu RK, etal., Biochim Biophys Acta. 2005 Mar 22;1743(1-2):86-92.
127. Determination of oxidative stress in vitiligo by measuring superoxide dismutase and catalase levels in vitiliginous and non-vitiliginous skin. Sravani PV, etal., Indian J Dermatol Venereol Leprol. 2009 May-Jun;75(3):268-71. doi: 10.4103/0378-6323.48427.
128. Oxidative stress in aging in the C57B16/J mouse cochlea. Staecker H, etal., Acta Otolaryngol. 2001 Sep;121(6):666-72.
129. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
130. Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin. Subudhi U and Chainy GB, Chem Biol Interact. 2010 Jan 27;183(2):304-16. doi: 10.1016/j.cbi.2009.11.004. Epub 2009 Nov 13.
131. Upregulation of catalase and downregulation of glutathione peroxidase activity in the kidney precede the development of hypertension in pre-hypertensive SHR. Sundaram A, etal., Hypertens Res. 2013 Mar;36(3):213-8. doi: 10.1038/hr.2012.163. Epub 2012 Oct 25.
132. Acatalasemic mice are mildly susceptible to adriamycin nephropathy and exhibit increased albuminuria and glomerulosclerosis. Takiue K, etal., BMC Nephrol. 2012 Mar 25;13:14. doi: 10.1186/1471-2369-13-14.
133. CCAAT/enhancer binding protein-beta (C/EBP-beta), a pivotal regulator of the TATA-less promoter in the rat catalase gene. Taniguchi M, etal., FEBS Lett. 2005 Oct 24;579(25):5785-90. Epub 2005 Oct 6.
134. Lipid peroxidation and some antioxidant enzymes in nasal polyp tissue. Taysi S, etal., Cell Biochem Funct. 2006 Sep-Oct;24(5):461-5.
135. Oxidant/antioxidant status in men with Behcet's disease. Taysi S, etal., Clin Rheumatol. 2007 Mar;26(3):418-22. Epub 2007 Jan 6.
136. Diosmin protects rat retina from ischemia/reperfusion injury. Tong N, etal., J Ocul Pharmacol Ther. 2012 Oct;28(5):459-66. Epub 2012 Apr 17.
137. Plasma lipid peroxidation products and antioxidant enzyme activities in patients with type 2 diabetes mellitus. Turk HM, etal., Acta Diabetol. 2002 Sep;39(3):117-22.
138. Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia. Tyagi N, etal., J Mol Neurosci. 2012 May;47(1):128-38. doi: 10.1007/s12031-011-9695-z. Epub 2012 Jan 3.
139. The role of oxidative mechanisms in the etiopathogenesis of pterygium: a preliminary study. Ucakhan OO, etal., Ophthalmologica. 2009;223(1):41-6. doi: 10.1159/000167020. Epub 2008 Nov 4.
140. Serum and BAL cytokine and antioxidant enzyme levels at different stages of pneumoconiosis in coal workers. Ulker O, etal., Hum Exp Toxicol. 2008 Dec;27(12):871-7.
141. Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa. Usui S, etal., Mol Ther. 2009 May;17(5):778-86. doi: 10.1038/mt.2009.47. Epub 2009 Mar 17.
142. Prolonged constriction of sciatic nerve affecting oxidative stressors & antioxidant enzymes in rat. Varija D, etal., Indian J Med Res. 2009 May;129(5):587-92.
143. Lipid peroxidation in proliferative vitreoretinopathies. Verdejo C, etal., Eye (Lond). 1999 Apr;13 ( Pt 2):183-8.
144. CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD. Vibhuti A, etal., Clin Chim Acta. 2010 Apr 2;411(7-8):474-80. Epub 2010 Jan 18.
145. Lipid Peroxidation and Altered Anti-oxidant Status in Breast Adenocarcinoma Patients. Wang C, etal., Drug Res (Stuttg). 2014 Jul 22.
146. Over-expression of antioxidant enzymes protects cultured hippocampal and cortical neurons from necrotic insults. Wang H, etal., J Neurochem 2003 Dec;87(6):1527-34.
147. Hyperbaric oxygen preconditioning attenuates early apoptosis after spinal cord ischemia in rats. Wang L, etal., J Neurotrauma. 2009 Jan;26(1):55-66.
148. Malondialdehyde and catalase as the serum biomarkers of allyl chloride-induced toxic neuropathy. Wang QS, etal., Toxicology. 2006 Oct 3;227(1-2):36-44. Epub 2006 Jul 10.
149. 17beta-Estradiol Ameliorates Light-Induced Retinal Damage in Sprague-Dawley Rats by Reducing Oxidative Stress. Wang S, etal., J Mol Neurosci. 2014 Jul 20.
150. Molecular analysis of human acatalasemia. Identification of a splicing mutation. Wen JK, etal., J Mol Biol 1990 Jan 20;211(2):383-93.
151. Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. Wenten M, etal., Am J Epidemiol. 2009 Dec 15;170(12):1494-501. Epub 2009 Nov 6.
152. Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence. Wolf N, etal., Exp Eye Res. 2005 Sep;81(3):276-85.
153. Identification of liver proteins and their roles associated with carbon tetrachloride-induced hepatotoxicity. Wong LL, etal., Hum Exp Toxicol. 2011 Sep;30(9):1369-81. doi: 10.1177/0960327110391388. Epub 2010 Dec 7.
154. Activity of antioxidant enzymes and concentration of lipid peroxidation products in selected tissues of mice of different ages, both healthy and melanoma-bearing. Wozniak A, etal., Z Gerontol Geriatr. 2004 Jun;37(3):184-9.
155. Intraperitoneal injection of Ginkgo biloba extract enhances antioxidation ability of retina and protects photoreceptors after light-induced retinal damage in rats. Xie Z, etal., Curr Eye Res. 2007 May;32(5):471-9.
156. Antioxidant activities of Dracocephalum tanguticum maxim extract and its up-regulation on the expression of neurotrophic factors in a rat model of permanent focal cerebral ischemia. Xu JX, etal., Am J Chin Med. 2011;39(1):65-81.
157. Unilateral ureteral obstruction evokes renal tubular apoptosis via the enhanced oxidative stress and endoplasmic reticulum stress in the rat. Yeh CH, etal., Neurourol Urodyn. 2011 Mar;30(3):472-9. doi: 10.1002/nau.20855. Epub 2011 Feb 8.
158. Inducing gene expression of cardiac antioxidant enzymes by dietary phenolic acids in rats. Yeh CT, etal., J Nutr Biochem. 2009 Mar;20(3):163-71. doi: 10.1016/j.jnutbio.2008.01.005. Epub 2008 Jun 10.
159. The effects of noise on hearing and oxidative stress in textile workers. Yildirim I, etal., Ind Health. 2007 Dec;45(6):743-9.
160. The role of oxidants and antioxidants in psoriasis. Yildirim M, etal., J Eur Acad Dermatol Venereol. 2003 Jan;17(1):34-6.
161. The effect of N-acetyl serotonin on ultraviolet-radiation-induced cataracts in rats. Yildirim N, etal., Ophthalmologica. 2003 Mar-Apr;217(2):148-53.
162. Oxidative damage and antioxidant enzyme activities in experimental hypothyroidism. Yilmaz S, etal., Cell Biochem Funct 2003 Dec;21(4):325-30.
163. Effects of zinc on interleukins and antioxidant enzyme values in psoriasis-induced mice. Yin LL, etal., Biol Trace Elem Res. 2013 Dec;155(3):411-5. doi: 10.1007/s12011-013-9799-0. Epub 2013 Sep 10.
164. Adrenomedullin reduces antioxidant defense system and enhances kidney tissue damage in cadmium and lead exposed rats. Yurekli M, etal., Environ Toxicol. 2009 Jun;24(3):279-86. doi: 10.1002/tox.20430.
165. Gadolinium chloride, a kupffer cell inhibitor, attenuates hepatic injury in a rat model of chronic cholestasis. Zandieh A, etal., Hum Exp Toxicol. 2011 Feb 21.
166. Pseudoxanthoma elasticum: genetic variations in antioxidant genes are risk factors for early disease onset. Zarbock R, etal., Clin Chem. 2007 Oct;53(10):1734-40. Epub 2007 Aug 10.
167. Geldanamycin Reduces Abeta-Associated Anxiety and Depression, Concurrent with Autophagy Provocation. Zare N, etal., J Mol Neurosci. 2015 Nov;57(3):317-24. doi: 10.1007/s12031-015-0619-1. Epub 2015 Jul 25.
168. Effect of Ginkgo leaf parenteral solution on blood and cochlea antioxidant and immunity indexes in OM rats. Zhao J, etal., Molecules. 2011 Dec 15;16(12):10433-42. doi: 10.3390/molecules161210433.
169. Polymorphisms in the promoter region of catalase gene and essential hypertension. Zhou XF, etal., Dis Markers. 2005;21(1):3-7.
170. Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury. Zmijewski JW, etal., Am J Respir Crit Care Med. 2009 Apr 15;179(8):694-704. Epub 2009 Jan 16.
Additional References at PubMed
PMID:642030   PMID:2895531   PMID:4975476   PMID:5087482   PMID:5929246   PMID:6547842   PMID:8153151   PMID:9053548   PMID:9600348   PMID:10514471   PMID:10617683   PMID:10656833  
PMID:11134921   PMID:11156684   PMID:11792727   PMID:11829486   PMID:12456800   PMID:12521604   PMID:12646716   PMID:12915479   PMID:14651853   PMID:15020231   PMID:15178682   PMID:15317809  
PMID:15372991   PMID:15489334   PMID:15734284   PMID:16210410   PMID:16238459   PMID:16644728   PMID:16770742   PMID:16781659   PMID:16854843   PMID:17053817   PMID:17215005   PMID:17275685  
PMID:17320761   PMID:17524832   PMID:17564305   PMID:17597213   PMID:17881773   PMID:18008141   PMID:18049893   PMID:18171680   PMID:18312938   PMID:18379038   PMID:18430061   PMID:19182904  
PMID:19302986   PMID:19479899   PMID:19891630   PMID:19940161   PMID:19946888   PMID:20063054   PMID:20178365   PMID:20387083   PMID:20830981   PMID:21295034   PMID:21423176   PMID:21460186  
PMID:21660462   PMID:21942371   PMID:21976670   PMID:21988832   PMID:22206666   PMID:22683338   PMID:22905402   PMID:23376485   PMID:23527889   PMID:23533145   PMID:23808586   PMID:23911387  
PMID:24669281   PMID:24740756   PMID:25639505   PMID:25931508   PMID:26071777   PMID:26459835   PMID:26503970   PMID:27221506   PMID:28290603   PMID:29568061   PMID:29847079   PMID:30361391  


Genomics

Comparative Map Data
Cat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,297,340 - 110,329,526 (-)NCBIGRCr8
mRatBN7.2389,842,393 - 89,874,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx393,335,845 - 93,368,082 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03101,934,911 - 101,967,152 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0399,765,855 - 99,798,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,379,872 - 93,412,058 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,379,874 - 93,412,058 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03100,021,857 - 100,054,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4388,654,077 - 88,686,212 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1388,550,504 - 88,582,640 (+)NCBI
Celera388,911,241 - 88,943,392 (-)NCBICelera
RH 3.4 Map3718.62RGD
Cytogenetic Map3q32NCBI
CAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381134,438,934 - 34,472,060 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1134,438,934 - 34,472,060 (+)EnsemblGRCh38hg38GRCh38
GRCh371134,460,481 - 34,493,607 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361134,417,054 - 34,450,183 (+)NCBINCBI36Build 36hg18NCBI36
Build 341134,417,053 - 34,450,179NCBI
Celera1134,607,658 - 34,640,793 (+)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1134,157,829 - 34,190,968 (+)NCBIHuRef
CHM1_11134,459,461 - 34,492,601 (+)NCBICHM1_1
T2T-CHM13v2.01134,575,773 - 34,608,901 (+)NCBIT2T-CHM13v2.0
Cat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,284,249 - 103,315,498 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,284,194 - 103,315,505 (-)EnsemblGRCm39 Ensembl
GRCm382103,453,904 - 103,485,153 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2103,453,849 - 103,485,160 (-)EnsemblGRCm38mm10GRCm38
MGSCv372103,294,061 - 103,325,310 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362103,254,842 - 103,285,959 (-)NCBIMGSCv36mm8
Celera2104,700,510 - 104,731,525 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.43NCBI
Cat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542211,781,835 - 11,827,464 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542211,783,973 - 11,826,970 (-)NCBIChiLan1.0ChiLan1.0
CAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2936,658,657 - 36,694,370 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11136,665,639 - 36,699,236 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01134,413,253 - 34,446,831 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11134,289,603 - 34,323,160 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,289,603 - 34,323,160 (+)Ensemblpanpan1.1panPan2
CAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11833,383,005 - 33,422,447 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1833,383,005 - 33,422,447 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1832,988,826 - 33,028,342 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01833,993,703 - 34,033,703 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1833,972,087 - 34,033,763 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11833,553,399 - 33,593,082 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01833,145,251 - 33,185,159 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01833,780,645 - 33,820,629 (-)NCBIUU_Cfam_GSD_1.0
Cat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494730,476,191 - 30,512,340 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365333,600,955 - 3,637,422 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365333,601,270 - 3,637,128 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl226,487,653 - 26,581,452 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1226,493,664 - 26,533,881 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2228,860,864 - 28,900,834 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2p16-p15NCBI
CAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1130,792,533 - 30,828,920 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl130,792,399 - 30,829,592 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038127,903,025 - 127,939,181 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cat
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476712,680,953 - 12,715,739 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476712,680,940 - 12,715,468 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cat
168 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:414
Count of miRNA genes:228
Interacting mature miRNAs:259
Transcripts:ENSRNOT00000011230
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat

Markers in Region
D3Mit7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2389,878,207 - 89,878,372 (+)MAPPERmRatBN7.2
Rnor_6.0393,415,673 - 93,415,837NCBIRnor6.0
Rnor_5.03100,057,451 - 100,057,615UniSTSRnor5.0
RGSC_v3.4388,648,421 - 88,648,585UniSTSRGSC3.4
RGSC_v3.4388,648,420 - 88,648,585RGDRGSC3.4
RGSC_v3.1388,544,848 - 88,545,013RGD
Celera388,947,023 - 88,947,189UniSTS
RH 3.4 Map3719.51RGD
RH 3.4 Map3719.51UniSTS
RH 2.0 Map3461.0RGD
FHH x ACI Map353.96RGD
Cytogenetic Map3q32-q34UniSTS
D3Arb10  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0393,413,543 - 93,413,837NCBIRnor6.0
Celera388,944,877 - 88,945,187UniSTS
RH 3.4 Map3716.91RGD
RH 3.4 Map3716.91UniSTS
SHRSP x BN Map346.7498UniSTS
SHRSP x BN Map346.7498RGD
FHH x ACI Map353.96RGD
Cytogenetic Map3q32-q34UniSTS
D3Hmgc1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.03100,055,227 - 100,055,344NCBIRnor5.0
RGSC_v3.4388,652,647 - 88,652,843RGDRGSC3.4
RGSC_v3.4388,652,648 - 88,652,843UniSTSRGSC3.4
Celera388,944,577 - 88,944,772UniSTS
RH 3.4 Map3717.41RGD
RH 3.4 Map3717.41UniSTS
Cytogenetic Map3q32-q34UniSTS
RH94469  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2389,842,709 - 89,842,859 (+)MAPPERmRatBN7.2
Rnor_6.0393,380,189 - 93,380,338NCBIRnor6.0
Rnor_5.03100,022,174 - 100,022,323UniSTSRnor5.0
RGSC_v3.4388,685,748 - 88,685,897UniSTSRGSC3.4
Celera388,911,558 - 88,911,707UniSTS
RH 3.4 Map3718.62UniSTS
Cytogenetic Map3q32-q34UniSTS
AW535533  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2389,847,000 - 89,847,179 (+)MAPPERmRatBN7.2
Rnor_6.0393,384,480 - 93,384,658NCBIRnor6.0
Rnor_5.03100,026,465 - 100,026,643UniSTSRnor5.0
RGSC_v3.4388,681,428 - 88,681,606UniSTSRGSC3.4
Celera388,915,849 - 88,916,027UniSTS
RH 3.4 Map3716.81UniSTS
Cytogenetic Map3q32-q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 8 8 8
Medium 3 43 49 33 19 33 8 11 74 35 34 11 8
Low 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000011230   ⟹   ENSRNOP00000011230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)Ensembl
Rnor_6.0 Ensembl393,379,874 - 93,412,058 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000120007   ⟹   ENSRNOP00000092755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)Ensembl
RefSeq Acc Id: NM_012520   ⟹   NP_036652
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83110,297,340 - 110,329,526 (-)NCBI
mRatBN7.2389,842,393 - 89,874,577 (-)NCBI
Rnor_6.0393,379,872 - 93,412,058 (-)NCBI
Rnor_5.03100,021,857 - 100,054,043 (-)NCBI
RGSC_v3.4388,654,077 - 88,686,212 (+)RGD
Celera388,911,241 - 88,943,392 (-)NCBI
Sequence:
RefSeq Acc Id: NP_036652   ⟸   NM_012520
- UniProtKB: P04762 (UniProtKB/Swiss-Prot),   A6HNR6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011230   ⟸   ENSRNOT00000011230
RefSeq Acc Id: ENSRNOP00000092755   ⟸   ENSRNOT00000120007
Protein Domains
Catalase core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P04762-F1-model_v2 AlphaFold P04762 1-527 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692253
Promoter ID:EPDNEW_R2778
Type:initiation region
Name:Cat_1
Description:catalase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0393,411,993 - 93,412,053EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2279 AgrOrtholog
BioCyc Gene G2FUF-48577 BioCyc
BioCyc Pathway DETOX1-PWY [superoxide radicals degradation] BioCyc
  DETOX1-PWY-1 [reactive oxygen species degradation] BioCyc
  PWY66-162 [ethanol degradation IV] BioCyc
BioCyc Pathway Image DETOX1-PWY BioCyc
  DETOX1-PWY-1 BioCyc
  PWY66-162 BioCyc
Ensembl Genes ENSRNOG00000008364 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055000198 UniProtKB/Swiss-Prot
  ENSRNOG00060001791 UniProtKB/Swiss-Prot
  ENSRNOG00065017370 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011230 ENTREZGENE
  ENSRNOT00000011230.6 UniProtKB/Swiss-Prot
  ENSRNOT00000120007.1 UniProtKB/TrEMBL
  ENSRNOT00055000340 UniProtKB/Swiss-Prot
  ENSRNOT00060002762 UniProtKB/Swiss-Prot
  ENSRNOT00065028977 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.91.20 UniProtKB/TrEMBL
  Catalase core domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109889 IMAGE-MGC_LOAD
InterPro Catalase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase_clade1/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase_haem_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase_immune_responsive UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24248 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93644 IMAGE-MGC_LOAD
NCBI Gene 24248 ENTREZGENE
PANTHER CATALASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11465 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Catalase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Catalase-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cat PhenoGen
PIRSF Catalase_clade1-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CATALASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CATALASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CATALASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CATALASE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008364 RatGTEx
  ENSRNOG00055000198 RatGTEx
  ENSRNOG00060001791 RatGTEx
  ENSRNOG00065017370 RatGTEx
SMART Catalase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56634 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AH65_RAT UniProtKB/TrEMBL
  A6HNR5_RAT UniProtKB/TrEMBL
  A6HNR6 ENTREZGENE, UniProtKB/TrEMBL
  CATA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Cat  Catalase      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 634701
gene_process functions as a hydrogen peroxide:hydrogen peroxide oxidoreductase 634701
gene_transcript 33 kb 634701