GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | decreases activity | EXP | | 6480464 | CTD | Vitamin K 3 results in decreased activity of CAT protein | PMID:30536483 | Cat | affects expression | ISO | CAT (Homo sapiens) | 6480464 | CTD | Vitamin K 3 affects the expression of CAT mRNA | PMID:20044591 | Cat | decreases response to substance | ISO | CAT (Homo sapiens) | 6480464 | CTD | CAT protein results in decreased susceptibility to Vitamin K 3 | PMID:14698046 PMID:15331536 | Cat | multiple interactions | ISO | CAT (Homo sapiens) | 6480464 | CTD | [CAT protein co-treated with SOD1 protein] results in decreased susceptibility to Vitamin K 3; [CAT protein co-treated with SOD2 protein] results in decreased susceptibility to Vitamin K 3; CAT protein inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; CAT protein inhibits the reaction [[DCXR protein results in increased metabolism of Vitamin K 3] which results in increased chemical synthesis of Hydrogen Peroxide]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid] | PMID:12633745 PMID:21689642 PMID:22486562 PMID:28595002 | | ||||||||||||||||||||||
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