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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catdecreases activityISOCat (Mus musculus)6480464CTDDextran Sulfate results in decreased activity of CAT proteinPMID:27125760 PMID:28421826 PMID:31737179
Catincreases activityISOCat (Mus musculus)6480464CTDDextran Sulfate results in increased activity of CAT proteinPMID:30489199
Catmultiple interactionsISOCat (Mus musculus)6480464CTD[Streptozocin co-treated with Dextran Sulfate] results in decreased expression of CAT protein; Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in increased activity of CAT protein]; gingerol inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]PMID:27125760 PMID:28421826 PMID:30489199 PMID:31737179 PMID:34964214
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