GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | decreases expression | EXP | | 6480464 | CTD | Lycopene results in decreased expression of CAT mRNA | PMID:26900785 | Cat | increases activity | EXP | | 6480464 | CTD | lycopene results in increased activity of CAT protein | PMID:20074268 | Cat | multiple interactions | EXP | | 6480464 | CTD | Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA] | PMID:16325981 PMID:17516994 PMID:17873360 PMID:26900785 PMID:27102619 PMID:31568845 PMID:32544411 | Cat | increases expression | ISO | CAT (Homo sapiens) | 6480464 | CTD | lycopene results in increased expression of CAT | PMID:19450652 | Cat | multiple interactions | ISO | Cat (Mus musculus) | 6480464 | CTD | Lycopene affects the reaction [Atrazine affects the expression of CAT mRNA]; Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT protein] | PMID:27989599 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 | | ||||||||||||||||||||||
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