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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:28260
Term: galactose
Definition: An aldohexose that is the C-4 epimer of glucose.
Chemical ID: MESH:D005690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cataffects activityEXP 6480464CTDGalactose affects the activity of CAT proteinPMID:32295448
Catdecreases activityEXP 6480464CTDGalactose results in decreased activity of CAT proteinPMID:34906534
Catincreases activityEXP 6480464CTDGalactose results in increased activity of CAT proteinPMID:17211565
Catmultiple interactionsEXP 6480464CTDcandesartan inhibits the reaction [Galactose results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Galactose results in increased activity of CAT protein]PMID:17211565 PMID:34906534
Catdecreases activityISOCat (Mus musculus)6480464CTDGalactose results in decreased activity of CAT proteinPMID:33761044
Catmultiple interactionsISOCat (Mus musculus)6480464CTD[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein; albicanol inhibits the reaction [Galactose results in decreased activity of CAT protein]; astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein]; Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein]PMID:33761044 PMID:35537655
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