Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of FNBP4 mRNA | CTD | PMID:23649840 | 17alpha-ethynylestradiol | affects expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of FNBP4 mRNA | CTD | PMID:17555576 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of FNBP4 mRNA | CTD | PMID:35192832 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Fnbp4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Fnbp4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FNBP4 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FNBP4 mRNA | CTD | PMID:34747641 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of FNBP4 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of FNBP4 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | ISO | FNBP4 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of FNBP4 mRNA | CTD | PMID:21179406 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FNBP4 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | increases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Fenretinide results in increased expression of FNBP4 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of FNBP4 mRNA | CTD | PMID:30047161 | aflatoxin B1 | increases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of FNBP4 mRNA | CTD | PMID:19770486 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of FNBP4 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FNBP4 mRNA | CTD | PMID:33212167 | arsenous acid | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FNBP4 mRNA | CTD | PMID:20458559 | benzo[a]pyrene | increases methylation | ISO | FNBP4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FNBP4 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:20018196 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FNBP4 mRNA | CTD | PMID:25181051 more ... | bisphenol A | decreases methylation | ISO | FNBP4 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of FNBP4 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of FNBP4 mRNA | CTD | PMID:32156529 and PMID:33221593 | bisphenol A | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of FNBP4 mRNA | CTD | PMID:29275510 | bisphenol A | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FNBP4 mRNA | CTD | PMID:28628672 | cadmium atom | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FNBP4 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of FNBP4 mRNA | CTD | PMID:33453195 | cadmium dichloride | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FNBP4 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | ISO | FNBP4 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of FNBP4 protein | CTD | PMID:35688186 | chlorpyrifos | decreases response to substance | ISO | FNBP4 (Homo sapiens) | 6480464 | FNBP4 gene mutant form results in decreased susceptibility to Chlorpyrifos | CTD | PMID:26299976 | chlorpyrifos | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Chlorpyrifos results in decreased expression of FNBP4 mRNA | CTD | PMID:26299976 | cisplatin | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FNBP4 mRNA | CTD | PMID:27594783 | clobetasol | decreases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of FNBP4 mRNA | CTD | PMID:27462272 | cobalt dichloride | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of FNBP4 mRNA | CTD | PMID:19376846 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of FNBP4 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of FNBP4 mRNA | CTD | PMID:30556269 | copper(II) sulfate | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of FNBP4 mRNA | CTD | PMID:19549813 | coumarin | decreases phosphorylation | ISO | FNBP4 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of FNBP4 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of FNBP4 mRNA | CTD | PMID:20106945 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of FNBP4 mRNA | CTD | PMID:23914054 | dexamethasone | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FNBP4 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FNBP4 mRNA | CTD | PMID:20458559 | doxorubicin | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of FNBP4 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of FNBP4 protein | CTD | PMID:23301498 | folic acid | decreases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of FNBP4 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of FNBP4 mRNA | CTD | PMID:20655997 | FR900359 | increases phosphorylation | ISO | FNBP4 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of FNBP4 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of FNBP4 mRNA | CTD | PMID:22061828 and PMID:33387578 | hydrogen peroxide | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FNBP4 protein | CTD | PMID:18951874 | indometacin | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FNBP4 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of FNBP4 protein | CTD | PMID:32959892 | leflunomide | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | leflunomide results in increased expression of FNBP4 mRNA | CTD | PMID:28988120 | mercury dichloride | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of FNBP4 mRNA | CTD | PMID:27188386 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of FNBP4 mRNA | CTD | PMID:30047161 | methylmercury chloride | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of FNBP4 mRNA | CTD | PMID:28001369 | ozone | multiple interactions | ISO | Fnbp4 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of FNBP4 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FNBP4 mRNA | CTD | PMID:33387578 | PCB138 | multiple interactions | ISO | Fnbp4 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | phenobarbital | affects expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of FNBP4 mRNA | CTD | PMID:19159669 | phenobarbital | affects expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Phenobarbital affects the expression of FNBP4 mRNA | CTD | PMID:23091169 | pirinixic acid | multiple interactions | ISO | Fnbp4 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of FNBP4 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of FNBP4 mRNA | CTD | PMID:20813756 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of FNBP4 mRNA | CTD | PMID:30047161 | quercetin | decreases phosphorylation | ISO | FNBP4 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of FNBP4 protein | CTD | PMID:35688186 | rac-lactic acid | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of FNBP4 mRNA | CTD | PMID:30851411 | silicon dioxide | decreases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of FNBP4 mRNA | CTD | PMID:19073995 | sodium arsenate | increases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of FNBP4 mRNA | CTD | PMID:21795629 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of FNBP4 mRNA | CTD | PMID:30047161 | tamoxifen | affects expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Tamoxifen affects the expression of FNBP4 mRNA | CTD | PMID:17555576 | temozolomide | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of FNBP4 mRNA | CTD | PMID:31758290 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of FNBP4 mRNA | CTD | PMID:16239168 | tetraphene | increases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of FNBP4 mRNA | CTD | PMID:26377693 | theophylline | multiple interactions | ISO | FNBP4 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of FNBP4 protein | CTD | PMID:18951874 | thimerosal | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of FNBP4 mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of FNBP4 mRNA | CTD | PMID:34492290 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of FNBP4 mRNA | CTD | PMID:33387578 | tris(2-butoxyethyl) phosphate | affects expression | ISO | FNBP4 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of FNBP4 mRNA | CTD | PMID:29024780 | triticonazole | decreases expression | EXP | | 6480464 | triticonazole results in decreased expression of FNBP4 mRNA | CTD | PMID:36084822 | trovafloxacin | increases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of FNBP4 mRNA | CTD | PMID:35537566 | tungsten | decreases expression | ISO | Fnbp4 (Mus musculus) | 6480464 | Tungsten results in decreased expression of FNBP4 mRNA | CTD | PMID:30912803 | valproic acid | affects expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FNBP4 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FNBP4 mRNA | CTD | PMID:23179753 more ... | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of FNBP4 mRNA | CTD | PMID:23034163 | vincristine | increases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Vincristine results in increased expression of FNBP4 mRNA | CTD | PMID:23649840 | vitamin E | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of FNBP4 mRNA | CTD | PMID:19244175 | vorinostat | decreases expression | ISO | FNBP4 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of FNBP4 mRNA | CTD | PMID:27188386 | |