Gene: Ptprj (protein tyrosine phosphatase, receptor type, J) Rattus norvegicus
Analyze
Symbol: Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Description: ENCODES a protein that exhibits beta-catenin binding (ortholog); delta-catenin binding (ortholog); gamma-catenin binding (ortholog); INVOLVED IN B cell differentiation (ortholog); blood coagulation (ortholog); calcium-mediated signaling using intracellular calcium source (ortholog); PARTICIPATES IN somatostatin signaling pathway; epidermal growth factor/neuregulin signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH hypertension; colon cancer (ortholog); colon carcinoma (ortholog); FOUND IN cell surface (ortholog); cell-cell junction (ortholog); immunological synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil
AGR Description: Predicted to have several functions, including beta-catenin binding activity, delta-catenin binding activity, and gamma-catenin binding activity; predicted to be involved in several processes, including animal organ development, regulation of cell motility, and regulation of signal transduction; predicted to localize to several cellular components, including the cell surface, cell-cell junction, and immunological synapse; used to study hypertension; orthologous to human PTPRJ (protein tyrosine phosphatase, receptor type J).
Merged Description: Predicted to have several functions, including beta-catenin binding activity, delta-catenin binding activity, and gamma-catenin binding activity; predicted to be involved in several processes, including animal organ development, regulation of cell motility, and regulation of signal transduction; predicted to localize to several cellular components, including the cell surface, cell-cell junction, and immunological synapse; used to study hypertension; orthologous to human PTPRJ (protein tyrosine phosphatase, receptor type J); PARTICIPATES IN somatostatin signaling pathway; epidermal growth factor/neuregulin signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: density enhanced phosphatase-1; DEP-1; protein tyrosine phosphatase receptor type J; receptor-type tyrosine-protein phosphatase eta
Orthologs:
Homo sapiens (human) : PTPRJ (protein tyrosine phosphatase receptor type J)  HGNC  Alliance
Mus musculus (house mouse) : Ptprj (protein tyrosine phosphatase, receptor type, J)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprj (protein tyrosine phosphatase receptor type J)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRJ (protein tyrosine phosphatase receptor type J)
Canis lupus familiaris (dog) : PTPRJ (protein tyrosine phosphatase, receptor type J)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprj (protein tyrosine phosphatase receptor type J)
Sus scrofa (pig) : PTPRJ (protein tyrosine phosphatase receptor type J)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0379,233,519 - 79,390,956 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0385,947,682 - 86,099,287 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4374,796,764 - 74,935,540 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1374,693,135 - 74,831,912 (-)NCBI
Celera375,621,921 - 75,777,388 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ptprj
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3454
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.