Dph6 (diphthamine biosynthesis 6) - Rat Genome Database

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Gene: Dph6 (diphthamine biosynthesis 6) Rattus norvegicus
Analyze
Symbol: Dph6
Name: diphthamine biosynthesis 6
RGD ID: 1310006
Description: Predicted to enable diphthine-ammonia ligase activity. Predicted to be involved in protein histidyl modification to diphthamide. Orthologous to human DPH6 (diphthamine biosynthesis 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP binding domain 4; ATP-binding domain-containing protein 4; Atpbd4; diphthamide synthase; diphthamide synthetase; diphthine--ammonia ligase; LOC362191; protein DPH6 homolog; RGD1310006; similar to RIKEN cDNA 5730421E18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83121,761,495 - 121,891,727 (-)NCBIGRCr8
mRatBN7.23101,307,229 - 101,437,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3101,307,231 - 101,534,603 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3104,953,722 - 105,084,612 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03113,552,760 - 113,683,650 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03111,229,816 - 111,359,981 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03106,007,721 - 106,136,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3106,009,356 - 106,136,615 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03112,579,626 - 112,708,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43100,397,745 - 100,536,300 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13100,294,173 - 100,432,728 (-)NCBI
Celera3100,276,488 - 100,405,912 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:23169644   PMID:24270810  


Genomics

Comparative Map Data
Dph6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83121,761,495 - 121,891,727 (-)NCBIGRCr8
mRatBN7.23101,307,229 - 101,437,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3101,307,231 - 101,534,603 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3104,953,722 - 105,084,612 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03113,552,760 - 113,683,650 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03111,229,816 - 111,359,981 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03106,007,721 - 106,136,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3106,009,356 - 106,136,615 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03112,579,626 - 112,708,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43100,397,745 - 100,536,300 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13100,294,173 - 100,432,728 (-)NCBI
Celera3100,276,488 - 100,405,912 (-)NCBICelera
Cytogenetic Map3q35NCBI
DPH6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381535,144,977 - 35,546,165 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1535,217,345 - 35,546,193 (-)EnsemblGRCh38hg38GRCh38
GRCh371535,663,081 - 35,838,366 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361533,450,375 - 33,625,656 (-)NCBINCBI36Build 36hg18NCBI36
Celera1512,422,457 - 12,597,717 (-)NCBICelera
Cytogenetic Map15q14NCBI
HuRef1512,508,418 - 12,683,435 (-)NCBIHuRef
CHM1_11535,781,103 - 35,956,346 (-)NCBICHM1_1
T2T-CHM13v2.01532,950,308 - 33,351,518 (-)NCBIT2T-CHM13v2.0
Dph6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392114,346,897 - 114,485,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2114,346,897 - 114,485,445 (-)EnsemblGRCm39 Ensembl
GRCm382114,516,416 - 114,655,046 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2114,516,416 - 114,654,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv372114,342,154 - 114,480,664 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362114,207,859 - 114,346,369 (-)NCBIMGSCv36mm8
Celera2115,641,036 - 115,775,887 (-)NCBICelera
Cytogenetic Map2E4NCBI
cM Map257.74NCBI
Dph6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554162,701,724 - 2,859,802 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554162,701,724 - 2,860,330 (-)NCBIChiLan1.0ChiLan1.0
DPH6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21624,382,251 - 24,768,176 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11528,747,480 - 28,923,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01514,293,746 - 14,469,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11532,554,276 - 32,729,455 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1532,554,276 - 32,729,455 (-)Ensemblpanpan1.1panPan2
DPH6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1303,000,723 - 3,146,568 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl302,980,437 - 3,146,568 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha303,000,875 - 3,196,175 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0303,066,202 - 3,261,206 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl303,113,310 - 3,261,963 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1302,999,857 - 3,195,107 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0303,099,636 - 3,295,078 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0303,228,666 - 3,423,950 (-)NCBIUU_Cfam_GSD_1.0
Dph6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864081,587,425 - 81,751,027 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936673400,722 - 567,184 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936673400,871 - 564,413 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPH6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1135,577,936 - 135,751,890 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11135,577,558 - 136,022,910 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21151,760,712 - 151,814,871 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DPH6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12647,360,989 - 47,799,830 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2647,361,674 - 47,539,119 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604893,111,378 - 93,560,397 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dph6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248042,563,712 - 2,783,551 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248042,565,130 - 2,783,641 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dph6
745 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:673
Count of miRNA genes:244
Interacting mature miRNAs:289
Transcripts:ENSRNOT00000056522
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)396127817102200699Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat

Markers in Region
RH140248  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23101,307,416 - 101,307,632 (+)MAPPERmRatBN7.2
Rnor_6.03106,007,898 - 106,008,113NCBIRnor6.0
Rnor_5.03112,579,803 - 112,580,018UniSTSRnor5.0
RGSC_v3.43100,397,922 - 100,398,137UniSTSRGSC3.4
Celera3100,276,665 - 100,276,880UniSTS
RH 3.4 Map3814.2UniSTS
Cytogenetic Map3q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 10 2 10 2 46 22 30 8
Low 3 43 47 39 9 39 8 11 28 13 11 3 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000056522   ⟹   ENSRNOP00000053362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3101,309,784 - 101,534,603 (-)Ensembl
Rnor_6.0 Ensembl3106,009,356 - 106,136,615 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095925   ⟹   ENSRNOP00000077519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3101,310,289 - 101,434,677 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107739   ⟹   ENSRNOP00000076614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3101,307,231 - 101,534,603 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114769   ⟹   ENSRNOP00000081524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3101,307,236 - 101,534,603 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117729   ⟹   ENSRNOP00000095038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3101,310,289 - 101,434,677 (-)Ensembl
RefSeq Acc Id: NM_001014181   ⟹   NP_001014203
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83121,761,506 - 121,891,658 (-)NCBI
mRatBN7.23101,307,240 - 101,437,394 (-)NCBI
Rnor_6.03106,007,721 - 106,136,662 (-)NCBI
Rnor_5.03112,579,626 - 112,708,200 (-)NCBI
RGSC_v3.43100,397,745 - 100,536,300 (-)RGD
Celera3100,276,488 - 100,405,912 (-)RGD
Sequence:
RefSeq Acc Id: XM_039105456   ⟹   XP_038961384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83121,761,495 - 121,891,727 (-)NCBI
mRatBN7.23101,308,936 - 101,437,463 (-)NCBI
RefSeq Acc Id: XM_063284157   ⟹   XP_063140227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83121,761,495 - 121,891,727 (-)NCBI
RefSeq Acc Id: XM_063284158   ⟹   XP_063140228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83121,768,216 - 121,891,727 (-)NCBI
RefSeq Acc Id: XM_063284159   ⟹   XP_063140229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83121,761,495 - 121,885,755 (-)NCBI
RefSeq Acc Id: XR_010064661
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83121,763,040 - 121,891,727 (-)NCBI
RefSeq Acc Id: XR_010064662
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83121,763,040 - 121,891,727 (-)NCBI
RefSeq Acc Id: NP_001014203   ⟸   NM_001014181
- UniProtKB: Q5M9F5 (UniProtKB/Swiss-Prot),   A0A8I5ZRV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000053362   ⟸   ENSRNOT00000056522
RefSeq Acc Id: XP_038961384   ⟸   XM_039105456
- Peptide Label: isoform X2
- UniProtKB: F1LP07 (UniProtKB/TrEMBL),   A0A8I5ZRV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000095038   ⟸   ENSRNOT00000117729
RefSeq Acc Id: ENSRNOP00000081524   ⟸   ENSRNOT00000114769
RefSeq Acc Id: ENSRNOP00000076614   ⟸   ENSRNOT00000107739
RefSeq Acc Id: ENSRNOP00000077519   ⟸   ENSRNOT00000095925
RefSeq Acc Id: XP_063140227   ⟸   XM_063284157
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZRV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140229   ⟸   XM_063284159
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063140228   ⟸   XM_063284158
- Peptide Label: isoform X3
Protein Domains
Diphthamide synthase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M9F5-F1-model_v2 AlphaFold Q5M9F5 1-267 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692300
Promoter ID:EPDNEW_R2824
Type:initiation region
Name:Dph6_1
Description:diphthamine biosynthesis 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03106,136,652 - 106,136,712EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310006 AgrOrtholog
BioCyc Gene G2FUF-48337 BioCyc
BioCyc Pathway PWY-7546 [diphthamide biosynthesis II (eukaryotes)] BioCyc
BioCyc Pathway Image PWY-7546 BioCyc
Ensembl Genes ENSRNOG00000037356 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055003283 UniProtKB/Swiss-Prot
  ENSRNOG00060020496 UniProtKB/Swiss-Prot
  ENSRNOG00065015904 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000056522.5 UniProtKB/TrEMBL
  ENSRNOT00000095925.1 UniProtKB/TrEMBL
  ENSRNOT00000107739 ENTREZGENE
  ENSRNOT00000107739.1 UniProtKB/Swiss-Prot
  ENSRNOT00000114769.1 UniProtKB/TrEMBL
  ENSRNOT00000117729.1 UniProtKB/TrEMBL
  ENSRNOT00055005137 UniProtKB/Swiss-Prot
  ENSRNOT00060036142 UniProtKB/Swiss-Prot
  ENSRNOT00065026600 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  putative n-type atp pyrophosphatase, domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131040 IMAGE-MGC_LOAD
InterPro Diphthami_syn_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DPH6/MJ0570 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362191 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95176 IMAGE-MGC_LOAD
NCBI Gene 362191 ENTREZGENE
PANTHER DIPHTHINE--AMMONIA LIGASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12196 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Diphthami_syn_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dph6 PhenoGen
PIRSF Diphthamide_synthase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000037356 RatGTEx
  ENSRNOG00055003283 RatGTEx
  ENSRNOG00060020496 RatGTEx
  ENSRNOG00065015904 RatGTEx
Superfamily-SCOP Adenine nucleotide alpha hydrolases-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YBV6_RAT UniProtKB/TrEMBL
  A0A8I5ZRV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASR8_RAT UniProtKB/TrEMBL
  DPH6_RAT UniProtKB/Swiss-Prot
  F1LP07 ENTREZGENE, UniProtKB/TrEMBL
  Q5M9F5 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-09 Dph6  diphthamine biosynthesis 6  Atpbd4  ATP binding domain 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Atpbd4  ATP binding domain 4  RGD1310006  similar to RIKEN cDNA 5730421E18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1310006  similar to RIKEN cDNA 5730421E18  RGD1310006_predicted  similar to RIKEN cDNA 5730421E18 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1310006_predicted  similar to RIKEN cDNA 5730421E18 (predicted)  LOC362191_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362191_predicted  similar to RIKEN cDNA 5730421E18 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL