Aplnr (apelin receptor) - Rat Genome Database

Name: Aplnr
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Aplnr (apelin receptor) Rattus norvegicus

Analyze

Symbol:

Aplnr

Name:

apelin receptor

RGD ID:

621645

Description:

Predicted to enable apelin receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cAMP-mediated signaling; and regulation of body fluid levels. Located in plasma membrane. Orthologous to human APLNR (apelin receptor); PARTICIPATES IN apelin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Agtrl1; angiotensin receptor-like 1; Apj; B78; G-protein coupled receptor APJ; GPCR34

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	APLNR (apelin receptor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Aplnr (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Aplnr (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	APLNR (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	APLNR (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Aplnr (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	APLNR (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	APLNR (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Aplnr (apelin receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	APLNR (apelin receptor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Aplnr (apelin receptor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	aplnrb (apelin receptor b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	aplnra (apelin receptor a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	npr-33	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Caenorhabditis elegans (roundworm):	npr-15	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	aplnr	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	90,624,055 - 90,627,700 (+)	NCBI		GRCr8
mRatBN7.2	3	70,217,407 - 70,221,052 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	70,217,385 - 70,221,050 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	73,599,092 - 73,602,742 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	82,197,771 - 82,201,425 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	79,962,920 - 79,966,570 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	72,540,538 - 72,544,183 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	72,540,538 - 72,544,182 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	79,052,120 - 79,055,765 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	68,365,637 - 68,369,282 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	68,262,008 - 68,265,653 (+)	NCBI
Celera	3	69,568,426 - 69,572,071 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-butoxyethanol (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

7,9-dihydro-1H-purine-2,6,8(3H)-trione (ISO)

acrylamide (EXP)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

Benzo[ghi]perylene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

buta-1,3-diene (ISO)

cantharidin (ISO)

carbon nanotube (ISO)

carmustine (ISO)

CGP 52608 (ISO)

chloroprene (EXP,ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clofibrate (ISO)

cocaine (EXP)

copper atom (EXP)

copper(0) (EXP)

cypermethrin (ISO)

cytarabine (ISO)

dioxygen (ISO)

diquat (ISO)

doxorubicin (ISO)

flavonoids (EXP)

folic acid (ISO)

fructose (EXP)

gentamycin (EXP)

hydrogen cyanide (ISO)

hydrogen peroxide (ISO)

methamphetamine (EXP)

N-ethyl-N-nitrosourea (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

niclosamide (ISO)

nitrofen (EXP)

Octicizer (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

phenformin (EXP)

phenobarbital (ISO)

phosgene (ISO)

phosphane (EXP)

pirinixic acid (ISO)

potassium cyanide (ISO)

rotenone (EXP)

SCH 23390 (EXP)

silicon dioxide (EXP)

sodium arsenate (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

tributyl phosphate (ISO)

trichloroethene (EXP)

triclosan (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

tris(2-chloroethyl) phosphate (ISO)

troglitazone (ISO)

uranium atom (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult heart development (ISO)

angiogenesis (IEA)

aorta development (ISO)

apelin receptor signaling pathway (IEA)

atrioventricular valve development (ISO)

blood vessel development (IBA)

coronary vasculature development (ISO,ISS)

endocardial cushion formation (ISO)

G protein-coupled receptor signaling pathway (IBA,IMP,ISO,ISS,TAS)

gastrulation (IEA)

heart development (IBA,ISS)

heart looping (ISO)

negative regulation of cAMP-mediated signaling (IBA,IMP,ISO,ISS)

negative regulation of gene expression (ISO)

positive regulation of angiogenesis (ISO,ISS)

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (ISO,ISS)

positive regulation of G protein-coupled receptor internalization (ISO)

positive regulation of release of sequestered calcium ion into cytosol (ISO,ISS)

regulation of body fluid levels (IMP)

regulation of gap junction assembly (ISO)

regulation of gene expression (ISO)

vascular associated smooth muscle cell differentiation (ISO)

vasculature development (ISO)

vasculogenesis (ISO,ISS)

venous blood vessel development (ISO)

ventricular septum morphogenesis (ISO)

Cellular Component

plasma membrane (IBA,IDA,ISO,ISS)

Molecular Function

apelin receptor activity (IBA)

G protein-coupled receptor activity (TAS)

peptide binding (TAS)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

apelin signaling pathway (TAS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin.	Hosoya M, etal., J Biol Chem 2000 Jul 14;275(28):21061-7.
4.	Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo.	Ishida J, etal., J Biol Chem 2004 Jun 18;279(25):26274-9. Epub 2004 Apr 15.
5.	Agonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptors.	Lee DK, etal., J Biol Chem 2004 Feb 27;279(9):7901-8. Epub 2003 Nov 26.
6.	Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin.	Medhurst AD, etal., J Neurochem 2003 Mar;84(5):1162-72.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	Regulation of rat APJ receptor messenger ribonucleic acid expression in magnocellular neurones of the paraventricular and supraopric nuclei by osmotic stimuli.	O'Carroll AM and Lolait SJ, J Neuroendocrinol 2003 Jul;15(7):661-6.
10.	Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues.	O'Carroll AM, etal., Biochim Biophys Acta 2000 Jun 21;1492(1):72-80.
11.	APJ receptor mRNA expression in the rat hypothalamic paraventricular nucleus: regulation by stress and glucocorticoids.	O'Carroll AM, etal., J Neuroendocrinol 2003 Nov;15(11):1095-101.
12.	Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.	Reaux A, etal., J Neurochem. 2001 May;77(4):1085-96.
13.	GOA pipeline	RGD automated data pipeline
14.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
16.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
17.	The novel peptide apelin regulates intrarenal artery tone in diabetic mice.	Zhong JC, etal., Regul Pept. 2007 Dec 4;144(1-3):109-14. Epub 2007 Jul 5.

Additional References at PubMed

PMID:11146423	PMID:15489334	PMID:16278022	PMID:17119870	PMID:18367654	PMID:18816630	PMID:19660504	PMID:20055692	PMID:20675385	PMID:22015267	PMID:22446510	PMID:22493882
PMID:22796316	PMID:23086141	PMID:23668014	PMID:24770651	PMID:24966188	PMID:25639753	PMID:25708823	PMID:25995451	PMID:26631739	PMID:27378063	PMID:27632349	PMID:27994053
PMID:28627589	PMID:28663440	PMID:28890073	PMID:28987634	PMID:30582943	PMID:32223946	PMID:36878020	PMID:37245722

Genomics

Comparative Map Data

Aplnr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	90,624,055 - 90,627,700 (+)	NCBI		GRCr8
mRatBN7.2	3	70,217,407 - 70,221,052 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	70,217,385 - 70,221,050 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	73,599,092 - 73,602,742 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	82,197,771 - 82,201,425 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	79,962,920 - 79,966,570 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	72,540,538 - 72,544,183 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	72,540,538 - 72,544,182 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	79,052,120 - 79,055,765 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	68,365,637 - 68,369,282 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	68,262,008 - 68,265,653 (+)	NCBI
Celera	3	69,568,426 - 69,572,071 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

APLNR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	57,233,591 - 57,237,250 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	57,233,577 - 57,237,250 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	57,001,065 - 57,004,724 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	56,757,643 - 56,761,489 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	56,757,629 - 56,761,364	NCBI
Celera	11	54,360,003 - 54,363,879 (-)	NCBI		Celera
Cytogenetic Map	11	q12.1	NCBI
HuRef	11	53,349,884 - 53,353,760 (-)	NCBI		HuRef
CHM1_1	11	56,867,161 - 56,871,037 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	57,183,042 - 57,186,701 (-)	NCBI		T2T-CHM13v2.0

Aplnr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	84,966,704 - 84,970,267 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	84,966,569 - 84,970,267 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	85,136,360 - 85,139,923 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	85,136,225 - 85,139,923 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	84,976,517 - 84,980,080 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	84,937,239 - 84,940,762 (+)	NCBI		MGSCv36	mm8
Celera	2	86,724,848 - 86,728,415 (+)	NCBI		Celera
Cytogenetic Map	2	D	NCBI
cM Map	2	49.45	NCBI

Aplnr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	2,322,920 - 2,324,068 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	2,321,445 - 2,324,417 (-)	NCBI	ChiLan1.0	ChiLan1.0

APLNR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	58,390,693 - 58,394,694 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	59,409,548 - 59,411,613 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	52,475,088 - 52,479,102 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	159,965,089 - 159,968,944 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	159,967,360 - 159,968,502 (-)	Ensembl	panpan1.1		panPan2

APLNR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	38,878,621 - 38,882,280 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	38,878,947 - 38,886,206 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	38,423,440 - 38,427,189 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	39,559,840 - 39,563,591 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	18	39,141,690 - 39,145,439 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	38,715,653 - 38,719,404 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	39,346,074 - 39,349,830 (+)	NCBI		UU_Cfam_GSD_1.0

Aplnr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	15,117,132 - 15,120,749 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	5,231,242 - 5,232,384 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	5,230,836 - 5,234,562 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

APLNR
(Sus scrofa - pig)

No map positions available.

APLNR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	16,007,092 - 16,011,868 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	16,008,300 - 16,009,601 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	113,347,578 - 113,351,438 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aplnr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624864	3,308,794 - 3,309,939 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624864	3,308,548 - 3,311,431 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Aplnr
14 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	302
Count of miRNA genes:	186
Interacting mature miRNAs:	234
Transcripts:	ENSRNOT00000012379
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	15005422	76927699	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	28249687	73249687	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	53781112	91609953	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	61134348	89115068	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	30684642	75684642	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	28249687	73249687	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
12879868	Am6	Aortic mass QTL 6		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	31426403	70668733	Rat
11565451	Bw177	Body weight QTL 177		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	3	31426403	70668733	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
11565452	Kidm57	Kidney mass QTL 57		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	31426403	70668733	Rat
12879866	Cm94	Cardiac mass QTL 94		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	31426403	70668733	Rat
12879867	Cm95	Cardiac mass QTL 95		0.047	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	31426403	70668733	Rat
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	43827364	90905114	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	53184692	89878207	Rat
2302055	Pia30	Pristane induced arthritis QTL 30	3.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	3	27936919	72936919	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	39454637	89115240	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	78196190	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	28468571	73468571	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	28468571	73468571	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	39454637	89115240	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	30684642	75684642	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	38517803	83517803	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	28249687	73249687	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	41874578	104104347	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	28249687	73249687	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	28249687	73249687	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
2301400	Cm68	Cardiac mass QTL 68		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	31426403	70668733	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat

Markers in Region

RH137244

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	70,220,828 - 70,221,025 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	72,543,960 - 72,544,156	NCBI	Rnor6.0
Rnor_5.0	3	79,055,542 - 79,055,738	UniSTS	Rnor5.0
RGSC_v3.4	3	68,369,059 - 68,369,255	UniSTS	RGSC3.4
Celera	3	69,571,848 - 69,572,044	UniSTS
Cytogenetic Map	3	q24	UniSTS

UniSTS:234445

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	70,217,597 - 70,217,860 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	72,540,729 - 72,540,991	NCBI	Rnor6.0
Rnor_5.0	3	79,052,311 - 79,052,573	UniSTS	Rnor5.0
RGSC_v3.4	3	68,365,828 - 68,366,090	UniSTS	RGSC3.4
Celera	3	69,568,617 - 69,568,879	UniSTS
Cytogenetic Map	3	q24	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		27	4	2		2	2	2	47	24	27	11	2
Low	3	16	39	25	19	25	6	9	27	11	12		6
Below cutoff			12	12		12					2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB033170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF090346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF184883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY942137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC072494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000012379 ⟹ ENSRNOP00000012379

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	70,217,385 - 70,221,050 (+)	Ensembl
Rnor_6.0 Ensembl	3	72,540,538 - 72,544,182 (+)	Ensembl

RefSeq Acc Id:

NM_031349 ⟹ NP_112639

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	90,624,055 - 90,627,700 (+)	NCBI
mRatBN7.2	3	70,217,407 - 70,221,052 (+)	NCBI
Rnor_6.0	3	72,540,538 - 72,544,183 (+)	NCBI
Rnor_5.0	3	79,052,120 - 79,055,765 (+)	NCBI
RGSC_v3.4	3	68,365,637 - 68,369,282 (+)	RGD
Celera	3	69,568,426 - 69,572,071 (+)	RGD

Sequence:

show sequence

GCTAGGACCAGGAAGGTAGAGGTGCAGCCGCCTGAGAAGCACATCCTGCTGGGTCTGAGCTCCC
AGAGAGGCTAGTTCTGCATGCCGGGAAGGGCTCTAAGCACCCTCAGACCACTTACTCTGAGGTT
TGAGCCAAGCCTCCAGGGTGCTTGCTGAGTTGCTGAGATAACTTTGGAGCTGGTGTCCCTGGGA
CTCACTGCCCAGCTTCCCTCCATTCACCACCATGGAAGATGATGGTTACAACTACTACGGGGCT
GACAACCAGTCTGAATGTGACTACGCAGACTGGACGCCCTCTGGAGCTCTCATCCCTGCCATCT
ACATTCTGGTTTTCCTTCTAGGCACCACAGGCAATGGCCTGGTGCTCTGGACCGTGTTTTGGAG
CAGCCGAGAAAAGAGACGCTCAGCTGACATCTTCATTGCCAGCCTGGCTGTGGCTGACTTGACC
TTTGTGGTGACTTTGCCACTGTGGGCCACTTATACCTACCGGGAGTTTGACTGGCCTTTTGGAA
CCTTCTCTTGCAAGCTCAGCAGCTACCTCATCTTTGTCAACATGTACGCCAGTGTCTTTTGCCT
CACCGGCCTCAGCTTTGACCGATACCTGGCCATTGTCAGGCCAGTGGCTAACGCTCGACTAAGG
CTGCGAGTCAGCGGGGCCGTGGCCACAGCAGTCTTGTGGGTGCTGGCTGCCCTTCTAGCTGTGC
CCGTCATGGTGTTCCGTTCCACTGACATCCCGGAAAACAGCACCAAGACCCAGTGCTACATGGA
CTACTCTATGGTGGCCACTTCAAACTCAGAGTGGGCCTGGGAGGTGGGCCTTGGGGTGTCCTCC
ACTGCTGTGGGCTTTGTGGTGCCCTTCATCATCATGCTGACCTGTTACTTCTTCATTGCCCAAA
CCATCGCTGGCCATTTCCGAAAGGAGCGCATCGAGGGCCTGCGGAAGAGGCGCCGGCTGCTGAG
CATCATCGTGGTGCTGGTGGTGACCTTTGCCCTGTGCTGGATGCCTTACCACCTGGTGAAGACT
CTCTACATGCTGGGCAATTTGCTGCACTGGCCCTGTGACTTTGACAGCTTCCTCATGAATGTCT
TTCCCTATTGCACCTGCATCAGTTACGTCAACAGCTGCCTCAACCCCTTCCTCTATGCCTTCTT
TGACCCCCGATTTCGCCGAGCCTGCACCTCCATGCTCTGCTGTGACCAGAGCGGGTGCAAAGGC
AGCCCTCACAGCAGCAGTGCAGAGAAATCTGCCAGTTATTCTTCTGGGCACAGCCAGGGCCCCG
GCCCCAACATGTGCAAGGGAGGAGAACCGATGCATGAGAAATCTATCCCCTATAGCCAAGAAAC
CCTTGTGGACTAGGGCTGGGACCAGAGGGAAGCCTGGTGCCTCGGGGCCTGACCCAAACTTCAT
CCTCACGCTCTGAGAACCAGGTAGCATGGCTTCTCCTGGACTCCGAATTCCCTTCTCTGCTCAC
CTCCAAGCTCTCTGCCTTGCTCCTCTCTTCTCACGCTTGTGGTTTAGTGGAAAGGGAAGGAGCC
TTGCAAACAGCTCAGCTGTTCAGTACTTCTGAGGTTGACCTTGCACAAGTCTCTTAACTTCTTG
AAACCTCAGTCACTTTGTTTGTAGTAAATGGGTCAATGTTAACCCTAAAGTGTTGAAGTGTGAG
TCCTGACCCAATTTGTTTCTTTCTGTTTGCTCAGCCCTCTGAGCTTTGGTTTTCTCTGTTGCAG
AAATTGTTTCTGTCAGCTACTCACTTTCTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCT
TTCTTTCTTTCTTTCTTTCTTTCTTTCTTTTTTTTTTCCGGAGCTGGGGACCGAACCCAGGGCC
TTCCGCTTGCTAGGCAAGCGCTCTACCACTGAGCTAAATCCCCAACCCCAGCTACTCACTTTCT
AGCGCTAACTCTTTCTCTTCTAGTGGCTTCCTCCCCCTCAAACCTTCCTGCCTATACTCAGTGC
CTTCTCCCCTGCTGGGCTTTTAAGGGTAAAGAACCCTGAAAATTGAAGAGTAACTTATCTTTTG
AGTTCTTGTCCTGTTTTCTGAGAGCCAGCAGGTGGCTGTATGTAGGCAAACAATGAATACTCTA
GTCCCCACAGCTCCGATCTTTCCAAAAAGTTGGATGAGTTCATTGTTGGTTCAGCCACCAGGGC
TAGACTGATCTTTGATTCTTTGGCAGAATCTCTATGATGCTTAGTGAATAATGCATCCTACCAA
TAACCAAGTATCCTTCCCATCACTTTTTAAAATTGTCTGTGAGAATTGCAAGGCAGCAGGGCTG
AGGTGGCTTTGGATGAAGGGGGAGTTGGGAAGGGAAAACAGAGAAAGGGTGAGAGGGGAATCTG
TATTTAGTCTGTATGCTGCTTGCCTCCCCTCCCCCAATCCTTGCCTCTCCACCTCCTACAGAAC
TGTGAACTGTAGAGCAGATCTTTCTCCTGTGTCCTCCCCCACCCTACCTTCTCTATAGGTTTTG
GTGCTATTTGGCACTAAGAGTCACTTGGTTAGGTAAGGCTATTTGGTTTTTGTCAATATGGGTA
TATATAAATATATATGCATGTGTGTGTATGTGTGTGTGTGCGCGACACACACCCAGAAGAGTAT
CACATAAGCTTCATTGATGAAGGACTGGGGTGAACCCCCACTCACTTTCTCCTGTGCTCCTATA
GGTCTCACAGACCACTTGGGGAAGAAGGACATATGGAGGGAGTGTAGAATAGATATGGGTCCAC
CCCCACTGGATTTGGGGAACTCCGACGGCTGGTCCGTATTTAGGAAAGAAGTCTATGTTTGTGC
TAGGCTTTCTGTAGGGAGCTGTTTCCTCAGTAGCATCTGGTTCTAAGGCTGGAGAAATCTGGAG
CTGGGCCCCAGTTCCTCTCCCCATTCCACAATGGCAAGAACAGACTTATAGACTATATCACGGC
CCTTCTCCTGTGTCCTTCCCTGGCTCTGACTTATTTCCCATCCCTCTCTCTTCGGGGTCTGTGT
CCCTCTTCCTAAGGAGGACACTTTCTTGCCACAGGATAAAGAATACAGGGTGAGCTTTTGGTCT
CTTCTCTGTCAGGACTGAGCCTCTTGGCTTCGCTGGCTCCTCTTGCTCCTTTGTGTGTGTGTGT
GTGGGGGGGGTAAGGTTGTGAAAGAGTGACTGAAGCCGCTGTGGGGCTCTCAAGGATCAAATTA
ATAGCGGGGCCTCTGTGAGCTGGAAATGGGTGTGTGTATTCCGGGTTTTGTTCTTGGAGGGCTC
TGGAAACCAAGGACAAGACATGTGCCATTGGACAGGAAGAGCCTGGCTTGATGCAGTTGGACCA
TCTCTGGCAGGGATCCTGCTCCTGGGGCAGAAAAGGGGGTTGTGGTGGTGGGGGATGGAGAAAA
CAGCTTTTCTTAGCTGAGCTCTGCATGTCTCAGGCCAGAAACTTTCACACAGCGTCTTCATCTG
CCAGGCCATCCTCAAAGCAGCCAGTACAGGCTGTAGGAGGCTTCTGGGAGACAGGAATCTCAAC
CATGACTGGGACAGACAGCAGCGGAGGCAGGCTCTCTTCCCCACCCCCATCCCACCTTCAGAAT
GCGCTTTTTTTTCCTGATCTTGTTAGTCACTGTGGTTCATCAAATAAAAACTGTTTTGTGTAAA
AAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_112639	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF80860	(Get FASTA)	NCBI Sequence Viewer
	AAG24468	(Get FASTA)	NCBI Sequence Viewer
	AAH72494	(Get FASTA)	NCBI Sequence Viewer
	AAY23011	(Get FASTA)	NCBI Sequence Viewer
	ABE41639	(Get FASTA)	NCBI Sequence Viewer
	BAA95002	(Get FASTA)	NCBI Sequence Viewer
	EDL79336	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000012379.4
	ENSRNOP00055030598
	ENSRNOP00060015337
	ENSRNOP00065033752
GenBank Protein	Q9JHG3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_112639 ⟸ NM_031349

- UniProtKB:

Q9ESK2 (UniProtKB/Swiss-Prot), Q9JHG3 (UniProtKB/Swiss-Prot), A6HMT5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEDDGYNYYGADNQSECDYADWTPSGALIPAIYILVFLLGTTGNGLVLWTVFWSSREKRRSADI
FIASLAVADLTFVVTLPLWATYTYREFDWPFGTFSCKLSSYLIFVNMYASVFCLTGLSFDRYLA
IVRPVANARLRLRVSGAVATAVLWVLAALLAVPVMVFRSTDIPENSTKTQCYMDYSMVATSNSE
WAWEVGLGVSSTAVGFVVPFIIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFA
LCWMPYHLVKTLYMLGNLLHWPCDFDSFLMNVFPYCTCISYVNSCLNPFLYAFFDPRFRRACTS
MLCCDQSGCKGSPHSSSAEKSASYSSGHSQGPGPNMCKGGEPMHEKSIPYSQETLVD

hide sequence

Ensembl Acc Id:

ENSRNOP00000012379 ⟸ ENSRNOT00000012379

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JHG3-F1-model_v2	AlphaFold	Q9JHG3	1-377	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692191

Promoter ID:

EPDNEW_R2716

Type:

single initiation site

Name:

Aplnr_1

Description:

apelin receptor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	72,540,512 - 72,540,572	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621645	AgrOrtholog
BioCyc Gene	G2FUF-49137	BioCyc
Ensembl Genes	ENSRNOG00000009227	Ensembl, UniProtKB/Swiss-Prot
	ENSRNOG00055021872	UniProtKB/Swiss-Prot
	ENSRNOG00060011535	UniProtKB/Swiss-Prot
	ENSRNOG00065024102	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000012379.5	UniProtKB/Swiss-Prot
	ENSRNOT00055037514	UniProtKB/Swiss-Prot
	ENSRNOT00060019521	UniProtKB/Swiss-Prot
	ENSRNOT00065041324	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7097318	IMAGE-MGC_LOAD
InterPro	Apelin_rcpt	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:83518	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:91642	IMAGE-MGC_LOAD
NCBI Gene	83518	ENTREZGENE
PANTHER	APELIN RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CELL ADHESION MOLECULE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Aplnr	PhenoGen
PRINTS	APJRECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000009227	RatGTEx
	ENSRNOG00055021872	RatGTEx
	ENSRNOG00060011535	RatGTEx
	ENSRNOG00065024102	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6HMT5	ENTREZGENE, UniProtKB/TrEMBL
	APJ_RAT	UniProtKB/Swiss-Prot
	Q9ESK2	ENTREZGENE
	Q9JHG3	ENTREZGENE
UniProt Secondary	Q9ESK2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-26	Aplnr	apelin receptor	Agtrl1	angiotensin receptor-like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-02-26	Agtrl1	angiotensin receptor-like 1			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Agtrl1	angiotensin receptor-like 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_process	involved in body fluid regulation	1304389
gene_process	involved in the regulation of hypothalamic function	1304460

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - ClinVar

RGD Manual Annotations