APLNR (apelin receptor) - Rat Genome Database

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Gene: APLNR (apelin receptor) Chlorocebus sabaeus
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Symbol: APLNR
Name: apelin receptor
RGD ID: 18574188
Description: ENCODES a protein that exhibits C-C chemokine binding (inferred); C-C chemokine receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); negative regulation of gene expression (ortholog); regulation of body fluid levels (ortholog); PARTICIPATES IN apelin signaling pathway; ASSOCIATED WITH intellectual disability (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: apelin receptor APJ
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,007,092 - 16,011,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,008,300 - 16,009,601 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038113,347,578 - 113,351,438 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
APLNR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,007,092 - 16,011,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,008,300 - 16,009,601 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038113,347,578 - 113,351,438 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
APLNR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,233,591 - 57,237,250 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,233,577 - 57,237,250 (-)EnsemblGRCh38hg38GRCh38
GRCh371157,001,065 - 57,004,724 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,757,643 - 56,761,489 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,757,629 - 56,761,364NCBI
Celera1154,360,003 - 54,363,879 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,349,884 - 53,353,760 (-)NCBIHuRef
CHM1_11156,867,161 - 56,871,037 (-)NCBICHM1_1
T2T-CHM13v2.01157,183,042 - 57,186,701 (-)NCBIT2T-CHM13v2.0
Aplnr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,966,704 - 84,970,267 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,966,569 - 84,970,267 (+)EnsemblGRCm39 Ensembl
GRCm38285,136,360 - 85,139,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl285,136,225 - 85,139,923 (+)EnsemblGRCm38mm10GRCm38
MGSCv37284,976,517 - 84,980,080 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36284,937,239 - 84,940,762 (+)NCBIMGSCv36mm8
Celera286,724,848 - 86,728,415 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
Aplnr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,624,055 - 90,627,700 (+)NCBIGRCr8
mRatBN7.2370,217,407 - 70,221,052 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl370,217,385 - 70,221,050 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx373,599,092 - 73,602,742 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0382,197,771 - 82,201,425 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,962,920 - 79,966,570 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,540,538 - 72,544,183 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,540,538 - 72,544,182 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0379,052,120 - 79,055,765 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,365,637 - 68,369,282 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1368,262,008 - 68,265,653 (+)NCBI
Celera369,568,426 - 69,572,071 (+)NCBICelera
Cytogenetic Map3q24NCBI
Aplnr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,322,920 - 2,324,068 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555112,321,445 - 2,324,417 (-)NCBIChiLan1.0ChiLan1.0
APLNR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,390,693 - 58,394,694 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,409,548 - 59,411,613 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01152,475,088 - 52,479,102 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13159,965,089 - 159,968,944 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3159,967,360 - 159,968,502 (-)Ensemblpanpan1.1panPan2
APLNR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,878,621 - 38,882,280 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,878,947 - 38,886,206 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,423,440 - 38,427,189 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01839,559,840 - 39,563,591 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11839,141,690 - 39,145,439 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,715,653 - 38,719,404 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01839,346,074 - 39,349,830 (+)NCBIUU_Cfam_GSD_1.0
Aplnr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494715,117,132 - 15,120,749 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365815,231,242 - 5,232,384 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365815,230,836 - 5,234,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APLNR
(Sus scrofa - pig)		 No map positions available.
Aplnr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248643,308,794 - 3,309,939 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248643,308,548 - 3,311,431 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 18 34 34 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000003969   ⟹   ENSCSAP00000002238
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl116,008,300 - 16,009,601 (+)Ensembl
RefSeq Acc Id: XM_037999316   ⟹   XP_037855244
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038113,347,578 - 113,351,438 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037855244 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein APH81103 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000002238.1
Ensembl Acc Id: ENSCSAP00000002238   ⟸   ENSCSAT00000003969
RefSeq Acc Id: XP_037855244   ⟸   XM_037999316
- UniProtKB: A0A0D9R0U9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005932 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003969.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro APJ_rcpt UniProtKB/TrEMBL
  GPCR1 UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report csab:103235513 UniProtKB/TrEMBL
NCBI Gene APLNR ENTREZGENE
PANTHER APELIN RECEPTOR UniProtKB/TrEMBL
  CELL ADHESION MOLECULE UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS APJRECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9R0U9 ENTREZGENE, UniProtKB/TrEMBL