APLNR (apelin receptor) - Rat Genome Database

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Gene: APLNR (apelin receptor) Sus scrofa
Analyze
Symbol: APLNR
Name: apelin receptor
RGD ID: 14215179
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); negative regulation of gene expression (ortholog); regulation of body fluid levels (ortholog); PARTICIPATES IN apelin signaling pathway; ASSOCIATED WITH intellectual disability (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:28532828   PMID:29576467   PMID:30032202  


Genomics

Comparative Map Data
APLNR
(Sus scrofa - pig)		 No map positions available.
APLNR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,233,591 - 57,237,250 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,233,577 - 57,237,250 (-)EnsemblGRCh38hg38GRCh38
GRCh371157,001,065 - 57,004,724 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,757,643 - 56,761,489 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,757,629 - 56,761,364NCBI
Celera1154,360,003 - 54,363,879 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,349,884 - 53,353,760 (-)NCBIHuRef
CHM1_11156,867,161 - 56,871,037 (-)NCBICHM1_1
T2T-CHM13v2.01157,183,042 - 57,186,701 (-)NCBIT2T-CHM13v2.0
Aplnr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,966,704 - 84,970,267 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,966,569 - 84,970,267 (+)EnsemblGRCm39 Ensembl
GRCm38285,136,360 - 85,139,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl285,136,225 - 85,139,923 (+)EnsemblGRCm38mm10GRCm38
MGSCv37284,976,517 - 84,980,080 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36284,937,239 - 84,940,762 (+)NCBIMGSCv36mm8
Celera286,724,848 - 86,728,415 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
Aplnr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,624,055 - 90,627,700 (+)NCBIGRCr8
mRatBN7.2370,217,407 - 70,221,052 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl370,217,385 - 70,221,050 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx373,599,092 - 73,602,742 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0382,197,771 - 82,201,425 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,962,920 - 79,966,570 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,540,538 - 72,544,183 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,540,538 - 72,544,182 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0379,052,120 - 79,055,765 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,365,637 - 68,369,282 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1368,262,008 - 68,265,653 (+)NCBI
Celera369,568,426 - 69,572,071 (+)NCBICelera
Cytogenetic Map3q24NCBI
Aplnr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,322,920 - 2,324,068 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555112,321,445 - 2,324,417 (-)NCBIChiLan1.0ChiLan1.0
APLNR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,390,693 - 58,394,694 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,409,548 - 59,411,613 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01152,475,088 - 52,479,102 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13159,965,089 - 159,968,944 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3159,967,360 - 159,968,502 (-)Ensemblpanpan1.1panPan2
APLNR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,878,621 - 38,882,280 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,878,947 - 38,886,206 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,423,440 - 38,427,189 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01839,559,840 - 39,563,591 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11839,141,690 - 39,145,439 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,715,653 - 38,719,404 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01839,346,074 - 39,349,830 (+)NCBIUU_Cfam_GSD_1.0
Aplnr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494715,117,132 - 15,120,749 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365815,231,242 - 5,232,384 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365815,230,836 - 5,234,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APLNR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,007,092 - 16,011,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,008,300 - 16,009,601 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038113,347,578 - 113,351,438 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aplnr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248643,308,794 - 3,309,939 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248643,308,548 - 3,311,431 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038869 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015016851 UniProtKB/TrEMBL
  ENSSSCG00025049096 UniProtKB/TrEMBL
  ENSSSCG00030054894 UniProtKB/TrEMBL
  ENSSSCG00035050946 UniProtKB/TrEMBL
  ENSSSCG00040056134 UniProtKB/TrEMBL
  ENSSSCG00045020484 UniProtKB/TrEMBL
  ENSSSCG00050060408 UniProtKB/TrEMBL
  ENSSSCG00055013096 UniProtKB/TrEMBL
  ENSSSCG00060024016 UniProtKB/TrEMBL
  ENSSSCG00065046359 UniProtKB/TrEMBL
  ENSSSCG00070025935 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000040165 ENTREZGENE
  ENSSSCT00000040165.1 UniProtKB/TrEMBL
  ENSSSCT00015022269.1 UniProtKB/TrEMBL
  ENSSSCT00025066842.1 UniProtKB/TrEMBL
  ENSSSCT00030076458.1 UniProtKB/TrEMBL
  ENSSSCT00035067863.1 UniProtKB/TrEMBL
  ENSSSCT00040076053.1 UniProtKB/TrEMBL
  ENSSSCT00045034903.1 UniProtKB/TrEMBL
  ENSSSCT00050082304.1 UniProtKB/TrEMBL
  ENSSSCT00055025743.1 UniProtKB/TrEMBL
  ENSSSCT00060032581.1 UniProtKB/TrEMBL
  ENSSSCT00065063432.1 UniProtKB/TrEMBL
  ENSSSCT00070051906.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro APJ_rcpt UniProtKB/TrEMBL
  GPCR1 UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
NCBI Gene APLNR ENTREZGENE
PANTHER APELIN RECEPTOR UniProtKB/TrEMBL
  CELL ADHESION MOLECULE UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS APJRECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A287A9Z5 ENTREZGENE
  A0A4X1VS06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IHM0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287A9Z5 UniProtKB/TrEMBL
VGNC ID VGNC:85412 ENTREZGENE