Ctnnd1 (catenin delta 1) - Rat Genome Database

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Gene: Ctnnd1 (catenin delta 1) Rattus norvegicus
Analyze
Symbol: Ctnnd1
Name: catenin delta 1
RGD ID: 1305643
Description: Enables beta-catenin binding activity; cell adhesion molecule binding activity; and protein tyrosine kinase binding activity. Predicted to be involved in several processes, including cell-cell adhesion mediated by cadherin; negative regulation of canonical Wnt signaling pathway; and protein stabilization. Predicted to act upstream of or within several processes, including glomerulus morphogenesis; positive regulation of protein metabolic process; and salivary gland development. Located in several cellular components, including dendritic spine; lamellipodium; and zonula adherens. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density, intracellular component. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in blepharocheilodontic syndrome 2. Orthologous to human CTNND1 (catenin delta 1); PARTICIPATES IN E-cadherin signaling pathway; fibroblast growth factor signaling pathway; N-cadherin signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: catenin (cadherin associated protein), delta 1; catenin delta-1; catenin src; Catns; LOC311163; P120; p120 catenin; p120-catenin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,090,025 - 90,141,247 (-)NCBIGRCr8
mRatBN7.2369,683,328 - 69,734,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl369,683,313 - 69,734,516 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx373,065,626 - 73,116,086 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0381,664,290 - 81,714,749 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,423,182 - 79,473,649 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,001,904 - 72,053,047 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,002,152 - 72,053,049 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0378,522,817 - 78,573,692 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,809,603 - 67,860,287 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1367,705,435 - 67,756,536 (-)NCBI
Celera369,039,896 - 69,090,199 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-tribromophenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (EXP)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
Goe 6976  (EXP)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
menadione  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
Monobutylphthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-phosphocreatine  (EXP)
ochratoxin A  (ISO)
ozone  (ISO)
p-cresol  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenol red  (ISO)
picoxystrobin  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
thifluzamide  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Differential expression of p120 catenin in glial cells of the adult rat brain. Chauvet N, etal., J Comp Neurol. 2004 Nov 1;479(1):15-29.
2. Distribution of p120 catenin during rat brain development: potential role in regulation of cadherin-mediated adhesion and actin cytoskeleton organization. Chauvet N, etal., Mol Cell Neurosci. 2003 Apr;22(4):467-86.
3. Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study. Chen YM, etal., Biol Reprod. 2003 Aug;69(2):656-72. Epub 2003 Apr 16.
4. Catenins in the rat epididymis: their expression and regulation in adulthood and during postnatal development. DeBellefeuille S, etal., Endocrinology. 2003 Nov;144(11):5040-9. doi: 10.1210/en.2002-0139. Epub 2003 Aug 13.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. The catenin, p120ctn, is a common membrane-associated protein in various epithelial and non-epithelial cells and tissues. Golenhofen N and Drenckhahn D, Histochem Cell Biol. 2000 Aug;114(2):147-55.
8. Protein kinase C-Fyn kinase cascade mediates the oleic acid-induced disassembly of neonatal rat cardiomyocyte adherens junctions. Hsu KL, etal., Int J Biochem Cell Biol. 2009 Jul;41(7):1536-46. Epub 2009 Jan 8.
9. Reduced expression of E-cadherin and p120-catenin and elevated expression of PLC-gamma1 and PIKE are associated with aggressiveness of oral squamous cell carcinoma. Jiang Y, etal., Int J Clin Exp Pathol. 2015 Aug 1;8(8):9042-51. eCollection 2015.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Endothelial-to-mesenchymal transition in pulmonary hypertension. Ranchoux B, etal., Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Distribution of adherens junction mediated by VE-cadherin complex in rat spleen sinus endothelial cells. Uehara K Cell Tissue Res. 2006 Mar;323(3):417-24. Epub 2005 Oct 22.
Additional References at PubMed
PMID:12370829   PMID:12734196   PMID:14610055   PMID:14657280   PMID:15138284   PMID:15166316   PMID:15331416   PMID:15775979   PMID:16399075   PMID:16510873   PMID:16973135   PMID:17047063  
PMID:17115030   PMID:17130295   PMID:17344476   PMID:17728463   PMID:18602475   PMID:18794329   PMID:18809680   PMID:19047464   PMID:19199708   PMID:19332538   PMID:19706605   PMID:20123964  
PMID:21521738   PMID:21718540   PMID:23990464   PMID:24046456   PMID:25468996   PMID:25931508   PMID:28051089   PMID:30995547  


Genomics

Comparative Map Data
Ctnnd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,090,025 - 90,141,247 (-)NCBIGRCr8
mRatBN7.2369,683,328 - 69,734,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl369,683,313 - 69,734,516 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx373,065,626 - 73,116,086 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0381,664,290 - 81,714,749 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,423,182 - 79,473,649 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,001,904 - 72,053,047 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,002,152 - 72,053,049 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0378,522,817 - 78,573,692 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,809,603 - 67,860,287 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1367,705,435 - 67,756,536 (-)NCBI
Celera369,039,896 - 69,090,199 (-)NCBICelera
Cytogenetic Map3q24NCBI
CTNND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,761,802 - 57,819,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,753,243 - 57,819,546 (+)EnsemblGRCh38hg38GRCh38
GRCh371157,529,274 - 57,587,012 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,285,810 - 57,343,228 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,285,844 - 57,343,226NCBI
Celera1154,886,498 - 54,943,699 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,877,613 - 53,935,179 (+)NCBIHuRef
CHM1_11157,396,253 - 57,453,671 (+)NCBICHM1_1
T2T-CHM13v2.01157,712,138 - 57,769,885 (+)NCBIT2T-CHM13v2.0
Ctnnd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,417,440 - 84,489,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,430,415 - 84,481,109 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl284,431,783 - 84,508,385 (-)EnsemblGRCm39 Ensembl
GRCm38284,587,096 - 84,658,977 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,600,071 - 84,650,765 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl284,601,439 - 84,678,041 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,440,938 - 84,490,897 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36284,401,622 - 84,451,512 (-)NCBIMGSCv36mm8
Celera286,195,656 - 86,245,817 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
Ctnnd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,658,858 - 2,703,958 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555112,658,879 - 2,705,992 (+)NCBIChiLan1.0ChiLan1.0
CTNND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,907,516 - 58,972,840 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,927,487 - 59,992,833 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01153,000,582 - 53,058,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11156,470,169 - 56,527,593 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1156,470,174 - 56,527,593 (+)Ensemblpanpan1.1panPan2
ZDHHC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,497,649 - 38,522,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,497,657 - 38,517,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,044,617 - 38,064,569 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01839,179,500 - 39,205,068 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1839,179,502 - 39,204,257 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,762,693 - 38,782,852 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,335,858 - 38,355,787 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,966,391 - 38,986,607 (-)NCBIUU_Cfam_GSD_1.0
Ctnnd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494714,638,778 - 14,688,432 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365814,750,947 - 4,802,289 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365814,750,845 - 4,802,262 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTNND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl213,154,338 - 13,209,250 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1213,143,604 - 13,209,251 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2212,789,450 - 12,842,242 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTNND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,408,581 - 15,466,457 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl115,411,454 - 15,466,456 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038112,759,621 - 112,817,271 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctnnd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248642,951,556 - 3,006,529 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248642,953,357 - 3,000,355 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ctnnd1
235 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:430
Count of miRNA genes:227
Interacting mature miRNAs:279
Transcripts:ENSRNOT00000064009
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
UniSTS:532273  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2369,683,575 - 69,684,544 (+)MAPPERmRatBN7.2
Rnor_6.0372,002,153 - 72,003,121NCBIRnor6.0
Rnor_5.0378,522,675 - 78,523,643UniSTSRnor5.0
Celera369,039,605 - 69,040,573UniSTS
Cytogenetic Map3q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 21 141 227 147 69 147 36 45 250 115 145 57 24
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000064009   ⟹   ENSRNOP00000063519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl369,683,313 - 69,734,498 (-)Ensembl
Rnor_6.0 Ensembl372,002,444 - 72,052,990 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081400   ⟹   ENSRNOP00000070326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl369,683,313 - 69,734,498 (-)Ensembl
Rnor_6.0 Ensembl372,002,152 - 72,053,049 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097596   ⟹   ENSRNOP00000082894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl369,683,329 - 69,734,516 (-)Ensembl
RefSeq Acc Id: NM_001107740   ⟹   NP_001101210
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,564 - 90,141,189 (-)NCBI
mRatBN7.2369,683,867 - 69,734,498 (-)NCBI
Rnor_6.0372,002,444 - 72,052,990 (-)NCBI
Rnor_5.0378,522,817 - 78,573,692 (-)NCBI
RGSC_v3.4367,809,603 - 67,860,287 (-)RGD
Celera369,039,896 - 69,090,199 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234452   ⟹   XP_006234514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,233 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
Rnor_6.0372,001,904 - 72,053,047 (-)NCBI
Rnor_5.0378,522,817 - 78,573,692 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234453   ⟹   XP_006234515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
Rnor_6.0372,003,840 - 72,053,047 (-)NCBI
Rnor_5.0378,522,817 - 78,573,692 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761987   ⟹   XP_008760209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,233 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
Rnor_6.0372,003,840 - 72,053,046 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104870   ⟹   XP_038960798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104871   ⟹   XP_038960799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104872   ⟹   XP_038960800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,550 (-)NCBI
RefSeq Acc Id: XM_039104873   ⟹   XP_038960801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,550 (-)NCBI
RefSeq Acc Id: XM_039104874   ⟹   XP_038960802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104875   ⟹   XP_038960803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104876   ⟹   XP_038960804
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_039104877   ⟹   XP_038960805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
mRatBN7.2369,683,328 - 69,734,550 (-)NCBI
RefSeq Acc Id: XM_039104878   ⟹   XP_038960806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,233 (-)NCBI
mRatBN7.2369,685,211 - 69,734,549 (-)NCBI
RefSeq Acc Id: XM_063283647   ⟹   XP_063139717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
RefSeq Acc Id: XM_063283648   ⟹   XP_063139718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,232 (-)NCBI
RefSeq Acc Id: XM_063283649   ⟹   XP_063139719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
RefSeq Acc Id: XM_063283650   ⟹   XP_063139720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8390,090,025 - 90,141,247 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101210 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420298 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420299 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420300 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420301 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420302 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420303 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420304 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234514 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234515 (Get FASTA)   NCBI Sequence Viewer  
  XP_008760209 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960798 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960799 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960800 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960801 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960802 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960803 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960804 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960805 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960806 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139717 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139718 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139719 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139720 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79305 (Get FASTA)   NCBI Sequence Viewer  
  EDL79306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063519.2
  ENSRNOP00000070326.2
  ENSRNOP00000082894.1
RefSeq Acc Id: NP_001101210   ⟸   NM_001107740
- UniProtKB: A6HMQ5 (UniProtKB/TrEMBL),   A0A8I5ZVG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234515   ⟸   XM_006234453
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JXM1 (UniProtKB/TrEMBL),   D3ZZZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234514   ⟸   XM_006234452
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JXM1 (UniProtKB/TrEMBL),   D3ZZZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760209   ⟸   XM_008761987
- Peptide Label: isoform X14
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070326   ⟸   ENSRNOT00000081400
Ensembl Acc Id: ENSRNOP00000063519   ⟸   ENSRNOT00000064009
RefSeq Acc Id: XP_038960801   ⟸   XM_039104873
- Peptide Label: isoform X6
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960805   ⟸   XM_039104877
- Peptide Label: isoform X12
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960800   ⟸   XM_039104872
- Peptide Label: isoform X5
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960804   ⟸   XM_039104876
- Peptide Label: isoform X11
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960803   ⟸   XM_039104875
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZVG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960802   ⟸   XM_039104874
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZVG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960798   ⟸   XM_039104870
- Peptide Label: isoform X2
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960806   ⟸   XM_039104878
- Peptide Label: isoform X14
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960799   ⟸   XM_039104871
- Peptide Label: isoform X3
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082894   ⟸   ENSRNOT00000097596
RefSeq Acc Id: XP_063139720   ⟸   XM_063283650
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZVG2 (UniProtKB/TrEMBL),   A6HMQ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139719   ⟸   XM_063283649
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZVG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139717   ⟸   XM_063283647
- Peptide Label: isoform X4
- UniProtKB: D3ZZZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139718   ⟸   XM_063283648
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZVG2 (UniProtKB/TrEMBL),   A6HMQ5 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZZ9-F1-model_v2 AlphaFold D3ZZZ9 1-932 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692177
Promoter ID:EPDNEW_R2702
Type:initiation region
Name:Ctnnd1_1
Description:catenin delta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0372,053,004 - 72,053,064EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305643 AgrOrtholog
BioCyc Gene G2FUF-49176 BioCyc
Ensembl Genes ENSRNOG00000030790 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064009.2 UniProtKB/TrEMBL
  ENSRNOT00000081400.2 UniProtKB/TrEMBL
  ENSRNOT00000097596.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  Plakophilin/d_Catenin UniProtKB/TrEMBL
KEGG Report rno:311163 UniProtKB/TrEMBL
NCBI Gene 311163 ENTREZGENE
PANTHER PTHR10372 UniProtKB/TrEMBL
  PTHR10372:SF6 UniProtKB/TrEMBL
Pfam Arm UniProtKB/TrEMBL
PharmGKB CTNND1 RGD
PhenoGen Ctnnd1 PhenoGen
PROSITE ARM_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030790 RatGTEx
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2JXM1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVG2 ENTREZGENE, UniProtKB/TrEMBL
  A6HMQ4 ENTREZGENE, UniProtKB/TrEMBL
  A6HMQ5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZZ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Ctnnd1  catenin delta 1  Ctnnd1  catenin (cadherin associated protein), delta 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ctnnd1  catenin (cadherin associated protein), delta 1   Ctnnd1_predicted  catenin (cadherin associated protein), delta 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ctnnd1_predicted  catenin (cadherin associated protein), delta 1 (predicted)  Catns_predicted  catenin src (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Catns_predicted  catenin src (predicted)      Symbol and Name status set to approved 70820 APPROVED