Enables beta-catenin binding activity; cell adhesion molecule binding activity; and protein tyrosine kinase binding activity. Involved in brain development. Located in several cellular components, including dendritic spine; lamellipodium; and zonula adherens. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density, intracellular component. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in blepharocheilodontic syndrome 2. Orthologous to human CTNND1 (catenin delta 1); PARTICIPATES IN E-cadherin signaling pathway; fibroblast growth factor signaling pathway; N-cadherin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of CTNND1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of and results in increased oxidation of CTNND1 mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of CTNND1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of and results in increased oxidation of CTNND1 mRNA
Go 6976 inhibits the reaction [4-cresol affects the localization of and results in decreased phosphorylation of CTNND1 protein], Go 6976 inhibits the reaction [4-cresol inhibits the reaction [CTNND1 protein binds to CDH2 protein]]
mangiferin inhibits the reaction [Paraquat results in decreased expression of and affects the localization of CTNND1 protein], mangiferin inhibits the reaction [Paraquat results in decreased expression of CTNND1 mRNA alternative form]
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of CTNND1 mRNA more ...
[Coumestrol co-treated with Resveratrol] results in decreased expression of CTNND1 mRNA, [Plant Extracts co-treated with Resveratrol] results in increased expression of CTNND1 mRNA
Distribution of p120 catenin during rat brain development: potential role in regulation of cadherin-mediated adhesion and actin cytoskeleton organization.
Reduced expression of E-cadherin and p120-catenin and elevated expression of PLC-gamma1 and PIKE are associated with aggressiveness of oral squamous cell carcinoma.
