Gene: Hdc (histidine decarboxylase) Rattus norvegicus
Analyze
Symbol:
Hdc
Name:
histidine decarboxylase
Description:
Exhibits anion binding activity; histidine decarboxylase activity; and identical protein binding activity. Involved in histamine metabolic process and histidine metabolic process. Localizes to cytosol; dendrite; and neuronal cell body. Biomarker of rhinitis. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; asthma; and rhinitis. Orthologous to human HDC (histidine decarboxylase); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; INTERACTS WITH 2,2',4,5'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2-nitrofluorene.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
MGC156577
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
HDC (histidine decarboxylase) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Hdc (histidine decarboxylase) HGNC
EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Hdc (histidine decarboxylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
HDC (histidine decarboxylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
HDC (histidine decarboxylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Hdc (histidine decarboxylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
HDC (histidine decarboxylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
HDC (histidine decarboxylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Hdc (histidine decarboxylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
DDC (dopa decarboxylase) HGNC
OrthoDB
Alliance orthologs 3
Mus musculus (house mouse):
Hdc (histidine decarboxylase)
Alliance
DIOPT (PANTHER|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid)
Homo sapiens (human):
HDC (histidine decarboxylase)
Alliance
DIOPT (PANTHER|HGNC|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector|Hieranoid)
Drosophila melanogaster (fruit fly):
hdc
Alliance
DIOPT (PANTHER|PhylomeDB|OrthoFinder|InParanoid|OrthoInspector)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 3 119,057,524 - 119,075,599 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 119,057,517 - 119,075,619 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 125,585,190 - 125,603,276 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 114,119,316 - 114,138,107 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 3 114,024,891 - 114,043,687 (-) NCBI Celera 3 112,689,823 - 112,707,916 (-) NCBI Celera Cytogenetic Map 3 q36 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
Gilles de la Tourette syndrome ISO RGD:736253 8554872 ClinVar Annotator: match by OMIM:137580 ClinVar PMID:20445167 , PMID:24411733
Imported Annotations - CTD
Hepatomegaly ISO RGD:736253 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:28108177 Imported Annotations - OMIM
Gilles de la Tourette syndrome ISO RGD:736253 7240710 OMIM
(R)-noradrenaline affects abundance ISO RGD:10706 6480464 HDC protein affects the abundance of Norepinephrine CTD PMID:12421355 1,1-dichloroethene decreases expression ISO RGD:10706 6480464 vinylidene chloride results in decreased expression of HDC mRNA CTD PMID:26682919 17alpha-ethynylestradiol increases expression ISO RGD:10706 6480464 Ethinyl Estradiol results in increased expression of HDC mRNA CTD PMID:17942748 17beta-estradiol decreases expression ISO RGD:10706 6480464 Estradiol results in decreased expression of HDC mRNA CTD PMID:15289156 2,2',4,5'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:29357290 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10706 6480464 Tetrachlorodibenzodioxin results in increased expression of HDC mRNA CTD PMID:17035482 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10706 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of HDC mRNA CTD PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of HDC mRNA CTD PMID:20959002 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10706 6480464 Tetrachlorodibenzodioxin affects the expression of HDC mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of HDC mRNA CTD PMID:15977195 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with LEP protein] affects the expression of HDC mRNA CTD PMID:15977195 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of HDC mRNA CTD PMID:15890375 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:20959002 3,3',5-triiodo-L-thyronine decreases expression EXP 6480464 Triiodothyronine results in decreased expression of HDC mRNA CTD PMID:29357290 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:10706 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of HDC mRNA CTD PMID:20188158 4,4'-sulfonyldiphenol increases expression ISO RGD:10706 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of HDC mRNA CTD PMID:30951980 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HDC mRNA CTD PMID:15890375 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of HDC mRNA CTD PMID:21346803 4-hydroxynon-2-enal decreases expression ISO RGD:10706 6480464 4-hydroxy-2-nonenal results in decreased expression of HDC mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO RGD:10706 6480464 Fenretinide results in increased expression of HDC mRNA CTD PMID:28973697 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of HDC mRNA CTD PMID:19483382 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases stability EXP 6480464 Omeprazole results in increased stability of HDC protein CTD PMID:12763636 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression EXP 6480464 Omeprazole results in increased expression of HDC mRNA CTD PMID:12763636 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions EXP 6480464 Omeprazole results in increased expression of and results in increased activity of HDC protein CTD PMID:12763636 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of HDC mRNA CTD PMID:19483382 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of HDC mRNA CTD PMID:24780913 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of HDC mRNA CTD PMID:22504374 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of HDC mRNA CTD PMID:28959563 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of HDC mRNA CTD PMID:15890375 alachlor increases expression EXP 6480464 alachlor results in increased expression of HDC mRNA CTD PMID:12419858 all-trans-retinoic acid decreases expression ISO RGD:736253 6480464 Tretinoin results in decreased expression of HDC mRNA CTD PMID:15894607 alpha-methylhistamine decreases expression EXP 6480464 alpha-methylhistamine results in decreased expression of HDC mRNA CTD PMID:11956952 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of HDC mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HDC mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of HDC mRNA CTD PMID:30779732 Atractylone multiple interactions ISO RGD:736253 6480464 atractylon inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein] CTD PMID:27553716 B 823-08 multiple interactions EXP 6480464 PD 136450 inhibits the reaction [B 823-08 results in increased expression of HDC mRNA] CTD PMID:7569754 B 823-08 increases expression EXP 6480464 B 823-08 results in increased expression of HDC mRNA CTD PMID:7569754 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of HDC mRNA CTD PMID:19483382 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of HDC mRNA CTD PMID:21839799 benzo[a]pyrene decreases expression ISO RGD:10706 6480464 Benzo(a)pyrene results in decreased expression of HDC mRNA CTD PMID:22228805 , PMID:25908611 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HDC mRNA CTD PMID:18164116 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HDC mRNA CTD PMID:25181051 bisphenol F increases expression ISO RGD:10706 6480464 bisphenol F results in increased expression of HDC mRNA CTD PMID:30951980 cadmium dichloride affects expression EXP 6480464 Cadmium Chloride affects the expression of HDC mRNA CTD PMID:22110744 Calcimycin multiple interactions ISO RGD:736253 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein more ... CTD PMID:27553716 Calcimycin increases expression ISO RGD:736253 6480464 Calcimycin results in increased expression of HDC mRNA CTD PMID:17191106 carbachol affects response to substance ISO RGD:10706 6480464 HDC protein affects the susceptibility to Carbachol CTD PMID:12893847 carbon nanotube increases expression ISO RGD:10706 6480464 Nanotubes, Carbon results in increased expression of HDC mRNA CTD PMID:25620056 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of HDC mRNA CTD PMID:19483382 clofibrate multiple interactions ISO RGD:10706 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HDC mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HDC mRNA] CTD PMID:17585979 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HDC mRNA CTD PMID:17602206 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of HDC mRNA CTD PMID:24386269 cocaine affects response to substance ISO RGD:10706 6480464 HDC gene mutant form affects the susceptibility to Cocaine CTD PMID:17072589 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of HDC mRNA CTD PMID:23640034 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Toluene 2 more ... CTD PMID:15054596 , PMID:18360087 dexamethasone multiple interactions ISO RGD:736253 6480464 Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein] CTD PMID:27553716 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of HDC mRNA CTD PMID:17075268 dexamethasone decreases activity EXP 6480464 Dexamethasone results in decreased activity of HDC protein CTD PMID:17075268 dichloroacetic acid increases expression ISO RGD:10706 6480464 Dichloroacetic Acid results in increased expression of HDC mRNA CTD PMID:28962523 dichlorvos increases activity EXP 6480464 Dichlorvos results in increased activity of HDC protein CTD PMID:119426 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of HDC mRNA CTD PMID:15890375 diethylstilbestrol decreases expression ISO RGD:10706 6480464 Diethylstilbestrol results in decreased expression of HDC mRNA CTD PMID:15171707 more ... dorsomorphin multiple interactions ISO RGD:736253 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HDC mRNA CTD PMID:27188386 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of HDC mRNA CTD PMID:29391264 fipronil increases expression EXP 6480464 fipronil results in increased expression of HDC mRNA CTD PMID:23962444 furan increases expression EXP 6480464 furan results in increased expression of HDC mRNA CTD PMID:25539665 gamma-aminobutyric acid multiple interactions ISO RGD:10706 6480464 HDC protein affects the reaction [Methamphetamine results in decreased abundance of gamma-Aminobutyric Acid] CTD PMID:12421355 genistein decreases expression ISO RGD:10706 6480464 Genistein results in decreased expression of HDC mRNA CTD PMID:15289156 , PMID:22553218 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of HDC mRNA CTD PMID:15159207 histamine increases chemical synthesis EXP 6480464 HDC protein results in increased chemical synthesis of Histamine CTD PMID:17075268 histamine multiple interactions ISO RGD:736253 6480464 [troglitazone results in decreased expression of HDC mRNA] which results in decreased secretion of Histamine CTD PMID:11834241 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of HDC mRNA CTD PMID:21396975 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of HDC mRNA CTD PMID:19483382 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of HDC mRNA CTD PMID:11578147 lead diacetate decreases expression ISO RGD:10706 6480464 lead acetate results in decreased expression of HDC mRNA CTD PMID:22609695 LY294002 multiple interactions ISO RGD:736253 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA] CTD PMID:16849647 methamphetamine multiple interactions ISO RGD:10706 6480464 HDC protein affects the reaction [Methamphetamine results in decreased abundance of gamma-Aminobutyric Acid] CTD PMID:12421355 methamphetamine affects response to substance ISO RGD:10706 6480464 HDC protein affects the susceptibility to Methamphetamine CTD PMID:12421355 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of HDC mRNA CTD PMID:15890375 methimazole increases expression EXP 6480464 Methimazole results in increased expression of HDC mRNA CTD PMID:22504374 milnacipran increases expression ISO RGD:10706 6480464 milnacipran results in increased expression of HDC mRNA CTD PMID:21157932 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of HDC mRNA CTD PMID:28801915 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HDC mRNA, [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HDC mRNA CTD PMID:17602206 , PMID:18164116 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of HDC mRNA CTD PMID:15890375 nevirapine decreases expression EXP 6480464 Nevirapine metabolite results in decreased expression of HDC mRNA CTD PMID:23947594 nickel atom increases expression ISO RGD:10706 6480464 Nickel results in increased expression of HDC mRNA CTD PMID:19839048 nickel atom increases expression ISO RGD:736253 6480464 Nickel results in increased expression of HDC mRNA CTD PMID:23195993 more ... nickel atom affects response to substance ISO RGD:10706 6480464 HDC affects the susceptibility to Nickel CTD PMID:19839048 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of HDC mRNA CTD PMID:22110744 nilotinib decreases expression ISO RGD:736253 6480464 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in decreased expression of HDC mRNA CTD PMID:16849647 nilotinib multiple interactions ISO RGD:736253 6480464 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA] CTD PMID:16849647 nitroglycerin decreases expression EXP 6480464 Nitroglycerin results in decreased expression of HDC mRNA CTD PMID:12102619 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of HDC mRNA CTD PMID:19483382 omeprazole increases stability EXP 6480464 Omeprazole results in increased stability of HDC protein CTD PMID:12763636 omeprazole increases expression EXP 6480464 Omeprazole results in increased expression of HDC mRNA CTD PMID:12763636 omeprazole multiple interactions EXP 6480464 Omeprazole results in increased expression of and results in increased activity of HDC protein CTD PMID:12763636 paracetamol multiple interactions ISO RGD:10706 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HDC mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HDC mRNA] CTD PMID:17585979 paracetamol affects expression ISO RGD:10706 6480464 Acetaminophen affects the expression of HDC mRNA CTD PMID:17562736 Pentagastrin increases activity EXP 6480464 Pentagastrin results in increased activity of HDC protein CTD PMID:67049 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of HDC mRNA CTD PMID:16221955 , PMID:19162173 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of HDC mRNA CTD PMID:16221955 , PMID:19162173 perfluorooctanoic acid decreases expression ISO RGD:736253 6480464 perfluorooctanoic acid results in decreased expression of HDC mRNA CTD PMID:23978341 phorbol 13-acetate 12-myristate increases activity ISO RGD:736253 6480464 Tetradecanoylphorbol Acetate results in increased activity of HDC protein CTD PMID:10428506 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:736253 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein more ... CTD PMID:27553716 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of HDC mRNA CTD PMID:15890375 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of HDC mRNA CTD PMID:19483382 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of HDC mRNA CTD PMID:15890375 more ... pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of HDC mRNA CTD PMID:19162173 progesterone affects expression ISO RGD:10706 6480464 Progesterone affects the expression of HDC, Progesterone affects the expression of HDC mRNA CTD PMID:16794005 , PMID:17251523 quercetin decreases expression ISO RGD:736253 6480464 Quercetin results in decreased expression of HDC mRNA CTD PMID:17191019 , PMID:17191106 SB 431542 multiple interactions ISO RGD:736253 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HDC mRNA CTD PMID:27188386 silicon dioxide increases expression ISO RGD:10706 6480464 Silicon Dioxide results in increased expression of HDC mRNA CTD PMID:23221170 sodium arsenite increases expression ISO RGD:736253 6480464 sodium arsenite results in increased expression of HDC mRNA CTD PMID:29301061 sodium dichromate affects expression EXP 6480464 sodium bichromate affects the expression of HDC mRNA CTD PMID:22110744 succimer multiple interactions ISO RGD:10706 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of HDC mRNA CTD PMID:21641980 tebuconazole decreases expression ISO RGD:736253 6480464 tebuconazole results in decreased expression of HDC mRNA CTD PMID:30458266 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of HDC mRNA CTD PMID:31150632 theophylline affects response to substance ISO RGD:10706 6480464 HDC protein affects the susceptibility to Theophylline CTD PMID:12893847 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of HDC mRNA CTD PMID:19483382 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of HDC mRNA CTD PMID:23411599 titanium dioxide decreases expression ISO RGD:10706 6480464 titanium dioxide results in decreased expression of HDC mRNA CTD PMID:23557971 toluene 2,4-diisocyanate multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Toluene 2 more ... CTD PMID:15054596 more ... toluene 2,4-diisocyanate increases expression EXP 6480464 Toluene 2, 4-Diisocyanate results in increased expression of HDC mRNA CTD PMID:15054596 more ... toluene 2,4-diisocyanate increases activity EXP 6480464 Toluene 2, 4-Diisocyanate results in increased activity of HDC protein CTD PMID:18360087 topotecan increases expression EXP 6480464 Topotecan results in increased expression of HDC mRNA CTD PMID:25729387 trichloroethene increases expression ISO RGD:10706 6480464 Trichloroethylene results in increased expression of HDC mRNA CTD PMID:28973375 troglitazone decreases expression ISO RGD:736253 6480464 troglitazone results in decreased expression of HDC mRNA CTD PMID:11834241 troglitazone multiple interactions ISO RGD:736253 6480464 [troglitazone results in decreased expression of HDC mRNA] which results in decreased secretion of Histamine CTD PMID:11834241 tungsten decreases expression ISO RGD:10706 6480464 Tungsten results in decreased expression of HDC mRNA CTD PMID:30912803 valproic acid decreases expression ISO RGD:736253 6480464 Valproic Acid results in decreased expression of HDC mRNA CTD PMID:23179753 valproic acid increases methylation ISO RGD:736253 6480464 Valproic Acid results in increased methylation of HDC gene CTD PMID:29154799 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of HDC mRNA CTD PMID:23869203 vorinostat increases expression ISO RGD:736253 6480464 vorinostat results in increased expression of HDC mRNA CTD PMID:26272509 vorinostat multiple interactions ISO RGD:736253 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HDC mRNA CTD PMID:27188386
Gene-Chemical Interaction Annotations
