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Gene: Spg11 (SPG11 vesicle trafficking associated, spatacsin) Rattus norvegicus
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Symbol: Spg11
Name: SPG11 vesicle trafficking associated, spatacsin
Description: Predicted to be involved in several processes, including axon extension; phagosome-lysosome fusion involved in apoptotic cell clearance; and synaptic vesicle transport. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin); INTERACTS WITH vinclozolin; (-)-epigallocatechin 3-gallate (ortholog); 2-methylcholine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC311372; RGD1562529; similar to hypothetical protein FLJ21439; spastic paraplegia 11 (autosomal recessive); spatacsin; SPG11, spatacsin vesicle trafficking associated
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03113,999,600 - 114,064,438 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03120,539,553 - 120,604,712 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43108,839,055 - 108,905,008 (-)NCBIRGSC3.4rn4RGSC3.4
Celera3107,906,940 - 107,971,094 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Spg11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562529
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.