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Gene: Bub1b (BUB1 mitotic checkpoint serine/threonine kinase B) Rattus norvegicus
Symbol: Bub1b
Name: BUB1 mitotic checkpoint serine/threonine kinase B
Description: Predicted to have protein kinase activity. Predicted to be involved in meiotic sister chromatid cohesion, centromeric; protein localization to chromosome, centromeric region; and regulation of mitotic sister chromatid separation. Predicted to colocalize with kinetochore. Human ortholog(s) of this gene implicated in colorectal cancer and mosaic variegated aneuploidy syndrome 1. Orthologous to human BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B); PARTICIPATES IN cell cycle pathway, mitotic; mitotic spindle checkpoint pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BUB1B, mitotic checkpoint serine/threonine kinase; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog beta (yeast); budding uninhibited by benzimidazoles 1 homolog, beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); LOC362192; mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03110,367,949 - 110,420,471 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,367,939 - 110,420,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03116,912,599 - 116,965,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,063,018 - 105,116,145 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13104,974,011 - 104,978,578 (+)NCBI
Celera3104,480,144 - 104,532,190 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Bub1b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619791
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.