Wipf1 (WAS/WASL interacting protein family, member 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Wipf1 (WAS/WASL interacting protein family, member 1) Rattus norvegicus
Analyze
Symbol: Wipf1
Name: WAS/WASL interacting protein family, member 1
RGD ID: 620887
Description: Predicted to enable SH3 domain binding activity and protein folding chaperone. Involved in actin cytoskeleton organization and positive regulation of protein export from nucleus. Located in actin filament. Orthologous to human WIPF1 (WAS/WASL interacting protein family member 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC108350583; translation initiation factor IF-2-like; WAS/WASL-interacting protein family member 1; WASP interacting protein; WASP-interacting protein; Waspip; Wip; Wiskott-Aldrich syndrome protein interacting protein; wiskott-Aldrich syndrome protein-interacting protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,721,486 - 78,824,199 (-)NCBIGRCr8
mRatBN7.2358,314,521 - 58,416,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl358,314,542 - 58,372,742 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx361,708,219 - 61,766,593 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0370,291,875 - 70,350,246 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0368,056,896 - 68,115,269 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0360,150,001 - 60,207,125 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl360,150,021 - 60,166,013 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0366,633,154 - 66,690,278 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4355,944,490 - 56,003,310 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1355,840,874 - 55,899,682 (-)NCBI
Celera357,842,394 - 57,900,610 (-)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carmustine  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
cytarabine  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
L-methionine  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
phenylmercury acetate  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
succimer  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. SPIN90/WISH interacts with PSD-95 and regulates dendritic spinogenesis via an N-WASP-independent mechanism. Lee S, etal., EMBO J. 2006 Oct 18;25(20):4983-95. Epub 2006 Sep 21.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. The rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation. Vetterkind S, etal., J Biol Chem 2002 Jan 4;277(1):87-95.
12. Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome. Volkman BF, etal., Cell 2002 Nov 15;111(4):565-76.
Additional References at PubMed
PMID:12147689   PMID:15489334   PMID:17229736   PMID:19798448   PMID:22966049  


Genomics

Comparative Map Data
Wipf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,721,486 - 78,824,199 (-)NCBIGRCr8
mRatBN7.2358,314,521 - 58,416,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl358,314,542 - 58,372,742 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx361,708,219 - 61,766,593 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0370,291,875 - 70,350,246 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0368,056,896 - 68,115,269 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0360,150,001 - 60,207,125 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl360,150,021 - 60,166,013 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0366,633,154 - 66,690,278 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4355,944,490 - 56,003,310 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1355,840,874 - 55,899,682 (-)NCBI
Celera357,842,394 - 57,900,610 (-)NCBICelera
Cytogenetic Map3q23NCBI
WIPF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382174,559,574 - 174,682,913 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2174,559,572 - 174,682,916 (-)EnsemblGRCh38hg38GRCh38
GRCh372175,424,302 - 175,547,641 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362175,132,548 - 175,255,873 (-)NCBINCBI36Build 36hg18NCBI36
Build 342175,249,808 - 175,324,811NCBI
Celera2169,037,733 - 169,161,112 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2167,305,224 - 167,428,467 (-)NCBIHuRef
CHM1_12175,430,425 - 175,553,733 (-)NCBICHM1_1
T2T-CHM13v2.02175,048,279 - 175,171,613 (-)NCBIT2T-CHM13v2.0
Wipf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39273,259,954 - 73,359,831 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl273,259,954 - 73,360,078 (-)EnsemblGRCm39 Ensembl
GRCm38273,429,610 - 73,529,487 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl273,429,610 - 73,529,734 (-)EnsemblGRCm38mm10GRCm38
MGSCv37273,267,674 - 73,367,467 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36273,230,456 - 73,330,249 (-)NCBIMGSCv36mm8
Celera275,116,177 - 75,216,066 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map243.68NCBI
Wipf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955449760,382 - 831,007 (+)NCBIChiLan1.0ChiLan1.0
WIPF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21377,223,785 - 77,347,483 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B77,238,760 - 77,362,431 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B61,837,128 - 61,960,468 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B179,290,685 - 179,316,694 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B179,290,685 - 179,316,695 (-)Ensemblpanpan1.1panPan2
WIPF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13618,574,298 - 18,653,255 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3618,576,813 - 18,697,103 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3618,583,586 - 18,706,041 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03618,710,269 - 18,832,843 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3618,710,269 - 18,832,790 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13618,787,537 - 18,909,829 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03618,785,832 - 18,908,163 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03618,896,780 - 19,019,287 (-)NCBIUU_Cfam_GSD_1.0
Wipf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303135,759,301 - 135,874,065 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365094,314,376 - 4,427,960 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WIPF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11580,521,032 - 80,646,462 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21589,758,529 - 89,797,790 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WIPF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11060,067,384 - 60,188,234 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1060,067,015 - 60,142,823 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040139,407,277 - 139,526,553 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wipf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478711,787,295 - 11,822,523 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478711,787,384 - 11,908,727 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wipf1
789 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:498
Count of miRNA genes:242
Interacting mature miRNAs:318
Transcripts:ENSRNOT00000024922
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat

Markers in Region
RH142360  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2358,314,165 - 58,314,327 (+)MAPPERmRatBN7.2
Rnor_6.0360,149,646 - 60,149,807NCBIRnor6.0
Rnor_5.0366,632,799 - 66,632,960UniSTSRnor5.0
RGSC_v3.4355,944,135 - 55,944,296UniSTSRGSC3.4
Celera357,842,039 - 57,842,200UniSTS
Cytogenetic Map3q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 16 22 14 19 14 1 1 30 22 31 11 1
Low 27 35 27 27 7 10 44 13 10 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000024922   ⟹   ENSRNOP00000024922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,314,542 - 58,372,742 (-)Ensembl
Rnor_6.0 Ensembl360,150,021 - 60,166,013 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109439   ⟹   ENSRNOP00000082687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,319,190 - 58,330,691 (-)Ensembl
RefSeq Acc Id: NM_057192   ⟹   NP_476540
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,722,042 - 78,780,277 (-)NCBI
mRatBN7.2358,314,521 - 58,372,742 (-)NCBI
Rnor_6.0360,150,001 - 60,207,125 (-)NCBI
Rnor_5.0366,633,154 - 66,690,278 (-)NCBI
RGSC_v3.4355,944,490 - 56,003,310 (-)RGD
Celera357,842,394 - 57,900,610 (-)RGD
Sequence:
RefSeq Acc Id: XM_039104135   ⟹   XP_038960063
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,721,486 - 78,824,199 (-)NCBI
mRatBN7.2358,314,521 - 58,416,668 (-)NCBI
RefSeq Acc Id: XM_039104136   ⟹   XP_038960064
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,721,486 - 78,824,198 (-)NCBI
mRatBN7.2358,314,521 - 58,416,666 (-)NCBI
RefSeq Acc Id: XM_039104137   ⟹   XP_038960065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,721,486 - 78,785,282 (-)NCBI
mRatBN7.2358,314,521 - 58,377,742 (-)NCBI
RefSeq Acc Id: XM_039104138   ⟹   XP_038960066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,721,486 - 78,750,762 (-)NCBI
mRatBN7.2358,314,521 - 58,343,381 (-)NCBI
RefSeq Acc Id: NP_476540   ⟸   NM_057192
- UniProtKB: Q8VDA4 (UniProtKB/Swiss-Prot),   Q6IN36 (UniProtKB/Swiss-Prot),   R9PXW1 (UniProtKB/TrEMBL),   A6HM96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024922   ⟸   ENSRNOT00000024922
RefSeq Acc Id: XP_038960063   ⟸   XM_039104135
- Peptide Label: isoform X1
- UniProtKB: Q8VDA4 (UniProtKB/Swiss-Prot),   Q6IN36 (UniProtKB/Swiss-Prot),   R9PXW1 (UniProtKB/TrEMBL),   A6HM96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960064   ⟸   XM_039104136
- Peptide Label: isoform X1
- UniProtKB: Q8VDA4 (UniProtKB/Swiss-Prot),   Q6IN36 (UniProtKB/Swiss-Prot),   R9PXW1 (UniProtKB/TrEMBL),   A6HM96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960065   ⟸   XM_039104137
- Peptide Label: isoform X1
- UniProtKB: Q8VDA4 (UniProtKB/Swiss-Prot),   Q6IN36 (UniProtKB/Swiss-Prot),   R9PXW1 (UniProtKB/TrEMBL),   A6HM96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960066   ⟸   XM_039104138
- Peptide Label: isoform X1
- UniProtKB: Q8VDA4 (UniProtKB/Swiss-Prot),   Q6IN36 (UniProtKB/Swiss-Prot),   R9PXW1 (UniProtKB/TrEMBL),   A6HM96 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000082687   ⟸   ENSRNOT00000109439
Protein Domains
WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IN36-F1-model_v2 AlphaFold Q6IN36 1-487 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620887 AgrOrtholog
BioCyc Gene G2FUF-49369 BioCyc
Ensembl Genes ENSRNOG00000018406 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055023131 UniProtKB/Swiss-Prot
  ENSRNOG00060015184 UniProtKB/Swiss-Prot
  ENSRNOG00065017440 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024922 ENTREZGENE
  ENSRNOT00000024922.7 UniProtKB/TrEMBL
  ENSRNOT00000109439.1 UniProtKB/TrEMBL
  ENSRNOT00055039758 UniProtKB/Swiss-Prot
  ENSRNOT00060026063 UniProtKB/Swiss-Prot
  ENSRNOT00065029144 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7100751 IMAGE-MGC_LOAD
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117538 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91527 IMAGE-MGC_LOAD
NCBI Gene 117538 ENTREZGENE
PANTHER OS06G0326200 PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WAS/WASL-INTERACTING PROTEIN FAMILY MEMBER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Wipf1 PhenoGen
PROSITE WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018406 RatGTEx
  ENSRNOG00055023131 RatGTEx
  ENSRNOG00060015184 RatGTEx
  ENSRNOG00065017440 RatGTEx
SMART WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6G7Q9_RAT UniProtKB/TrEMBL
  A6HM96 ENTREZGENE, UniProtKB/TrEMBL
  Q6IN36 ENTREZGENE
  Q8VDA4 ENTREZGENE
  R9PXW1 ENTREZGENE, UniProtKB/TrEMBL
  WIPF1_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q8VDA4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Wipf1  WAS/WASL interacting protein family, member 1  LOC108350583  translation initiation factor IF-2-like  Data merged from RGD:11498189 737654 PROVISIONAL
2016-08-02 LOC108350583  translation initiation factor IF-2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-25 Wipf1  WAS/WASL interacting protein family, member 1  Waspip  Wiskott-Aldrich syndrome protein interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Waspip  Wiskott-Aldrich syndrome protein interacting protein      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Waspip  Wiskott-Aldrich syndrome protein interacting protein      Symbol and Name status set to provisional 70820 PROVISIONAL