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Gene: Atf2 (activating transcription factor 2) Rattus norvegicus
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Symbol: Atf2
Name: activating transcription factor 2
Description: Exhibits cAMP response element binding activity; protein heterodimerization activity; and transcription factor binding activity. Involved in several processes, including amelogenesis; positive regulation of neuron apoptotic process; and regulation of transcription by RNA polymerase II. Localizes to the nucleus. Used to study hypertension and transient cerebral ischemia. Biomarker of glaucoma and transient cerebral ischemia. Orthologous to human ATF2 (activating transcription factor 2); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; influenza A pathway; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cAMP response element-binding protein CRE-BP1; cAMP-dependent transcription factor ATF-2; cyclic AMP-dependent transcription factor ATF-2; RATF2
Orthologs:
Homo sapiens (human) : ATF2 (activating transcription factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Atf2 (activating transcription factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf2 (activating transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF2 (activating transcription factor 2)
Canis lupus familiaris (dog) : ATF2 (activating transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf2 (activating transcription factor 2)
Sus scrofa (pig) : ATF2 (activating transcription factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0360,721,137 - 60,795,951 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0367,199,880 - 67,274,694 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4356,403,676 - 56,496,473 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1356,323,607 - 56,392,845 (-)NCBI
Celera358,247,269 - 58,321,865 (-)NCBICelera
Cytogenetic Map3q23NCBI
RH 3.4 Map5689.89RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Atf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621862
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.